Data for ST003203
| Metabolite structure | All data | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1-Met-His | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| 3-Met-His | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.01 | 0.00 | 0.00 | |
| 5-AVA | 0.02 | 0.01 | 0.01 | 0.01 | 0.02 | 0.01 | 0.04 | 0.02 | 0.01 | 0.02 | 0.01 | 0.01 | |
| AABA | 0.50 | 0.49 | 0.52 | 0.50 | 0.55 | 0.54 | 0.50 | 0.52 | 0.49 | 0.58 | 0.52 | 0.54 | |
| Ac-Orn | - | - | - | - | - | - | - | - | - | - | - | - | |
| ADMA | 0.05 | 0.04 | 0.07 | 0.05 | 0.05 | 0.05 | 0.04 | 0.06 | 0.03 | 0.05 | 0.06 | 0.07 | |
| Ala | 5.58 | 4.47 | 8.79 | 2.20 | 7.12 | 4.65 | 4.27 | 4.63 | 2.36 | 10.80 | 3.18 | 3.42 | |
| alpha-AAA | - | - | - | 0.02 | 0.01 | 0.05 | - | 0.00 | 0.00 | 0.01 | - | 0.01 | |
| Anserine | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.04 | 0.01 | 0.01 | |
| Arg | 0.66 | 0.45 | 0.98 | 0.41 | 0.59 | 0.40 | 0.40 | 0.40 | 0.30 | 0.69 | 0.19 | 0.23 | |
| Asn | 0.48 | 0.44 | 0.75 | 0.35 | 0.56 | 0.54 | 0.56 | 0.70 | 0.30 | 0.70 | 0.45 | 0.65 | |
| Asp | 2.73 | 2.10 | 4.09 | 2.02 | 3.36 | 2.45 | 3.54 | 2.64 | 1.73 | 3.24 | 2.21 | 2.34 | |
| BABA | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | |
| Betaine | 0.24 | 0.79 | 0.45 | 0.44 | 0.40 | 0.67 | 0.47 | 0.26 | 0.28 | 0.37 | 0.42 | 0.43 | |
| c4-OH-Pro | - | - | - | - | - | 0.00 | - | 0.01 | - | - | 0.00 | - | |
| Carnosine | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.08 | |
| Cit | 1.25 | 1.02 | 1.79 | 0.81 | 0.93 | 0.65 | 1.17 | 0.77 | 0.51 | 0.87 | 0.55 | 0.71 | |
| Creatinine | 2.35 | 1.68 | 2.82 | 2.00 | 2.67 | 2.54 | 2.21 | 2.69 | 2.20 | 3.13 | 2.24 | 2.38 | |
| Cys | 0.04 | 0.04 | 0.07 | 0.03 | 0.03 | 0.03 | 0.04 | 0.07 | 0.02 | 0.04 | 0.03 | 0.03 | |
| Cystine | 0.00 | 0.00 | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.00 | 0.01 | 0.00 | 0.00 | |
| DOPA | 0.11 | 0.11 | 0.11 | 0.11 | 0.11 | 0.11 | 0.11 | 0.12 | 0.10 | 0.10 | 0.11 | 0.13 | |
| Gln | 1.81 | 0.82 | 3.98 | 1.55 | 3.83 | 2.22 | 1.81 | 3.52 | 1.91 | 3.16 | 1.82 | 2.57 | |
| Glu | 6.23 | 3.54 | 8.15 | 4.29 | 6.80 | 5.90 | 5.25 | 6.16 | 3.91 | 6.88 | 4.20 | 5.60 | |
| Gly | 4.35 | 3.74 | 8.12 | 5.17 | 5.48 | 3.15 | 4.37 | 4.47 | 6.95 | 4.53 | 5.17 | 3.65 | |
| HArg | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.00 | 0.01 | 0.00 | 0.00 | |
| HCys | 0.11 | 0.11 | 0.12 | 0.13 | 0.11 | 0.10 | 0.13 | 0.10 | 0.21 | 0.11 | 0.11 | 0.10 | |
| His | 0.26 | 0.22 | 0.35 | 0.29 | 0.31 | 0.27 | 0.25 | 0.25 | 0.25 | 0.27 | 0.24 | 0.23 | |
| Ile | 0.84 | 0.77 | 1.30 | 0.69 | 0.95 | 0.59 | 1.20 | 0.89 | 0.65 | 0.80 | 0.68 | 0.77 | |
| Kynurenine | 0.17 | 0.18 | 0.18 | 0.19 | 0.19 | 0.17 | 0.17 | 0.18 | 0.16 | 0.19 | 0.19 | 0.16 | |
| Leu | 1.76 | 1.57 | 1.95 | 1.37 | 1.81 | 1.32 | 1.99 | 1.63 | 1.22 | 1.77 | 1.52 | 1.63 | |
| Lys | - | - | - | - | - | - | - | - | - | - | - | - | |
| Met | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 | 0.71 | 0.71 | 0.71 | 0.70 | 0.70 | 0.70 | 0.71 | |
| Met-SO | 0.17 | 0.15 | 0.20 | 0.15 | 0.18 | 0.16 | 0.18 | 0.17 | 0.15 | 0.18 | 0.16 | 0.19 | |
| Nitro-Tyr | - | 0.01 | - | - | - | - | - | - | - | - | 0.01 | - | |
| Orn | 0.13 | 1.47 | 1.56 | 0.26 | 0.22 | - | 0.09 | 0.10 | - | 0.02 | 0.13 | - | |
| PAG | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | 0.01 | 0.01 | 0.01 | |
| Phe | 0.36 | 0.17 | 0.52 | 0.18 | 0.41 | 0.29 | 0.34 | 0.23 | 0.06 | 0.61 | 0.11 | 0.17 | |
| PheAlaBetaine | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| Pro | 1.92 | 1.85 | 2.57 | 1.57 | 2.16 | 1.63 | 2.39 | 1.98 | 1.13 | 2.26 | 1.48 | 1.81 | |
| ProBetaine | 0.11 | 0.11 | 0.12 | 0.13 | 0.11 | 0.11 | 0.12 | 0.12 | 0.15 | 0.13 | 0.11 | 0.11 | |
| Sarcosine | 0.10 | 0.11 | 0.12 | 0.10 | 0.15 | 0.10 | 0.12 | 0.14 | 0.10 | 0.15 | 0.11 | 0.13 | |
| SDMA | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| Ser | 4.50 | 4.18 | 8.28 | 3.22 | 4.38 | 2.80 | 5.59 | 3.69 | 2.04 | 3.86 | 2.39 | 2.81 | |
| t4-OH-Pro | 0.15 | 0.13 | 0.18 | 0.12 | 0.17 | 0.22 | 0.14 | 0.19 | 0.14 | 0.24 | 0.18 | 0.18 | |
| Taurine | 8.89 | 2.37 | 12.88 | 6.28 | 13.16 | 9.24 | 5.70 | 11.37 | 7.37 | 16.09 | 7.62 | 8.87 | |
| Thr | 1.08 | 0.90 | 1.88 | 0.71 | 1.13 | 0.63 | 1.30 | 1.02 | 0.44 | 1.08 | 0.62 | 0.82 | |
| TMAO | 0.07 | 0.07 | 0.06 | 0.07 | 0.09 | 0.06 | 0.09 | 0.09 | 0.09 | 0.09 | 0.08 | 0.09 | |
| Trigonelline | 0.04 | 0.04 | 0.06 | 0.07 | 0.06 | 0.08 | 0.06 | 0.05 | 0.05 | 0.05 | 0.07 | 0.07 | |
| Trp | 0.12 | 0.06 | 0.24 | 0.12 | 0.13 | 0.08 | 0.12 | 0.10 | 0.05 | 0.16 | 0.07 | 0.11 | |
| TrpBetaine | 0.03 | 0.02 | 0.04 | 0.02 | 0.03 | 0.03 | 0.03 | 0.02 | 0.03 | 0.02 | 0.03 | 0.03 | |
| Tyr | 0.80 | 0.67 | 1.12 | 0.56 | 0.83 | 0.52 | 0.99 | 0.73 | 0.36 | 0.80 | 0.49 | 0.62 | |
| Val | 1.02 | 0.65 | 1.72 | 0.54 | 1.36 | 0.58 | 1.38 | 0.94 | 0.23 | 1.31 | 0.69 | 0.76 |
Factors:
| F1 | Study Arm:1 | Timepoint:Week 10 | PZC (< 660 ug/L):N |
| F2 | Study Arm:1 | Timepoint:Week 10 | PZC (< 660 ug/L):Y |
| F3 | Study Arm:1 | Timepoint:Week 18 | PZC (< 660 ug/L):N |
| F4 | Study Arm:1 | Timepoint:Week 18 | PZC (< 660 ug/L):Y |
| F5 | Study Arm:1 | Timepoint:Week 2 | PZC (< 660 ug/L):N |
| F6 | Study Arm:1 | Timepoint:Week 2 | PZC (< 660 ug/L):Y |
| F7 | Study Arm:2 | Timepoint:Week 10 | PZC (< 660 ug/L):N |
| F8 | Study Arm:2 | Timepoint:Week 10 | PZC (< 660 ug/L):Y |
| F9 | Study Arm:2 | Timepoint:Week 18 | PZC (< 660 ug/L):N |
| F10 | Study Arm:2 | Timepoint:Week 18 | PZC (< 660 ug/L):Y |
| F11 | Study Arm:2 | Timepoint:Week 2 | PZC (< 660 ug/L):N |
| F12 | Study Arm:2 | Timepoint:Week 2 | PZC (< 660 ug/L):Y |