Metabolomics Workbench : NIH Data Repository : Analyze Studies

Data for ST003297

(Analysis AN005401): Average values per metabolite and experimental factor (Units:uM)

Metabolite structure	F1	F2	F3	F4	F5
1,3-BPG	21.56	96.71	3.02	1.00	48.61
2-2-Dimethyl Succinic acid	7.76	9.51	21.37	21.00	18.60
2,3-BPG	17.30	137.96	0.28	0.29	0.24
2/3-Phosphoglyceric acid	1.26	1.92	0.66	0.72	1.45
2-3-Pyridinedicarboxylic acid	379.24	514.65	3280.36	485.08	-
2-Aminoadipic acid	1.14	1.83	1.38	1.36	2.95
2-Deoxyadenosine	-	0.04	8.42	8.45	12.64
2-Deoxyadenosine 5-diphosphate	88.67	4.55	339.05	502.96	506.09
2-Deoxyadenosine 5-monophosphate	0.02	0.09	-	-	-
2-Deoxyadenosine 5-triphosphate	12.71	12.27	12.18	11.97	11.81
2-Deoxycytidine	1.09	1.42	12.57	12.54	19.65
2-Deoxycytidine 5-diphosphate	72.70	66.13	0.29	0.30	13.49
2-Deoxycytidine 5-monophosphate	0.23	0.25	-	-	-
2-Deoxyguanosine	-	0.01	0.97	0.75	0.87
2-Deoxyinosine	437.91	1426.27	283.80	465.97	748.31
2-Deoxy-ribose	-	0.18	-	-	0.37
2-Deoxyribose 5-phosphate	0.48	0.49	0.00	-	-
2-Deoxyuridine	0.03	0.01	0.26	0.14	0.42
2-Deoxyuridine 5-triphosphate	2.02	1.97	2.24	2.20	2.15
2-Isopropylmalic acid	1.64	2.59	3.14	2.89	4.70
4-Hydroxyglutamic acid	3255.18	6127.67	9126.54	7276.31	21086.17
4-Hydroxyphenyl-pyruvic acid	13.98	19.49	68.05	38.75	8.47
4-Pyridoxic acid	314.52	591.26	2932.79	2624.13	2810.38
5-Deoxy-5-(methylthio)adenosine	4.55	4.51	2.67	2.74	2.65
5-Hydroxy-3-indoleacetic acid	23.36	14.43	34.08	28.67	3.08
5-Methylcytosine	126.56	189.15	0.85	0.41	3.31
Acetoacetate	-	-	-	-	-
Aceto-acetyl CoA Isovaleryl-CoA	4652.14	5096.70	731.42	2349.38	830.98
Acetyl-CoA	2.31	2.61	0.98	1.01	0.95
Adenine	0.27	0.25	0.28	0.36	0.36
Adenosine	2.14	2.75	0.15	0.14	0.01
Adenosine 3-5-cyclic monophosphate	0.05	0.10	0.19	0.19	0.18
Adenosine 5-diphosphate	179.83	157.10	0.32	0.17	0.03
Adenosine 5-monophosphate	431.25	379.86	-	-	-
Adenosine 5-triphosphate	452.15	320.32	97.94	38.96	7.44
Adenylosuccinic acid	8544.79	9592.77	1429.03	923.84	1444.22
Adipic acid	0.55	0.68	2.91	2.88	2.21
AICAR	-	0.02	0.41	0.36	0.33
AICAR-P	259.48	328.68	16.53	81.96	18.75
Alanine/Sarcosine	605.82	596.90	354.17	293.11	36.11
Allantoin	159.46	384.55	899.05	1029.73	702.73
alpha-D-Glucose-1-phosphate	1.36	1.71	0.01	0.01	-
alpha-D(+)Mannose 1-phosphate	1.70	2.91	0.21	0.20	0.19
alpha-Ketoglutaric acid	14.06	14.66	18.01	15.59	10.56
Arabinose-5-phosphate	0.95	2.12	0.19	-	-
Arginine	-	0.51	-	-	72.73
Asparagine	7.25	5.74	0.89	0.30	0.01
Aspartic Acid	27.60	54.88	11.90	7.23	2.98
beta-Nicotinamide adenine dinucleotide	43.62	36.70	-	-	-
b-Hydroxy Butyric acid	289.81	37.34	69.48	197.28	9.73
Butyryl-CoA Isobutyryl-CoA	2598.83	1855.64	1196.75	2148.59	3328.01
Carnitine	0.04	0.08	-	-	-
Carnosine	1.40	1.40	1.25	1.25	1.38
cis-Aconitic acid	14.50	11.28	4.78	4.05	0.08
Citramalic acid	6.51	5.33	1.46	1.42	1.67
Citric acid / Isocitric acid	95.15	61.05	108.86	69.06	31.49
Citrulline	70.63	48.97	56.38	33.77	0.02
Coenzyme A	8.16	10.22	10.62	8.02	10.80
Creatine	755.00	907.20	19.74	14.81	23.49
Creatine phosphate	29.82	59.32	343.72	150.10	275.32
Creatinine	2.89	4.43	2.23	2.40	3.27
Cystathionine	0.11	0.09	1.94	-	-
Cystine	0.07	0.05	2.57	2.91	10.23
Cytidine	0.30	0.50	0.01	0.01	0.18
Cytidine 5-diphosphate	54.63	50.14	-	-	-
Cytidine 5-monophosphate	7.78	9.63	-	-	-
Cytidine 5-triphosphate	43.94	33.04	20.02	3.53	0.12
Cytosine	0.52	0.56	0.01	0.01	0.01
Deoxycytidine 5-triphosphate	1.42	1.39	1.12	0.76	0.72
Deoxythymidine 5-triphosphate	8.75	8.12	3.55	3.18	3.06
Dihydroorotic acid	4.84	8.21	3.13	1.78	1.46
Dihydroxyacetone phosphate	76.18	141.60	3.96	3.83	5.53
Disaccharide	0.32	2.21	10.89	12.42	12.53
Erythro-Dihydrosphingosine	9110.68	10184.15	1803.44	198.22	2494.15
Erythrose 4-phosphate	0.22	0.23	-	-	-
Flavin adenine dinucleotide	1.10	1.10	1.07	1.08	1.10
Fructose 1,6-biphosphate	21.72	56.93	0.53	0.93	0.43
Fructose 6-phosphate	2.84	4.73	-	-	-
Galactonic acid	2.28	5.79	1.33	1.31	1.48
Galactosamine	999.06	1200.09	274.46	232.38	44.31
gamma-Glu-Cys	1.92	2.37	0.04	0.04	0.01
Gluconic acid	0.54	1.51	0.69	0.73	0.95
Glucose 6-phosphate	16.51	21.22	0.20	0.13	0.12
Glutamic acid	289.19	355.25	158.88	109.34	56.08
Glutamine	615.91	782.11	317.54	333.71	737.01
Glutathione (oxidized)	3.88	6.35	0.82	0.45	0.23
Glutathione (reduced)	261.91	362.13	2.08	1.40	4.07
Glyceraldehyde 3-phosphate	0.00	0.00	0.00	0.00	0.00
Glyceric acid	1.07	1.91	13.06	11.47	14.16
Guanine	1.65	2.35	0.08	0.10	0.07
Guanosine	1.51	3.09	0.20	0.20	0.20
Guanosine 5-diphosphate	26.37	24.34	0.63	0.84	1.08
Guanosine 5-triphosphate	463.04	335.71	136.09	66.93	3.99
Hexoses	394.64	777.82	5155.43	5380.77	7860.91
Histidine	66.26	56.92	43.15	41.74	48.74
Homocitrate	46.62	119.65	415.02	438.53	617.83
Homocysteine	4.20	25.99	283.36	328.05	24.27
Homocystine	0.05	0.06	0.05	0.04	0.04
Homoserine	39.83	46.90	15.61	22.15	20.43
Hydroxyglutaric acid	0.68	0.93	1.31	1.07	1.40
Hypotaurine	13.90	26.25	-	-	-
Hypoxanthine	284.62	395.66	41.88	10.44	721.26
Inosine	14.36	17.30	0.54	0.53	0.55
Inosine 5-diphosphate	79.36	71.15	2.06	1.26	0.20
Inosine 5-monophosphate	3.39	3.87	2.38	2.39	2.42
Inosine 5-triphosphate	153.14	102.51	42.37	24.27	16.76
Isoleucine	224.61	206.36	396.95	341.36	645.59
Isopentenyl pyrophosphate	2280.16	1404.06	4603.56	12091.83	647.63
Isopentyl acetate	20.11	13.01	19.08	9.11	3.46
Itaconic acid	-	-	-	-	-
Ketovaleric acid	100.07	105.12	504.80	474.44	296.02
Kynurenine	1.37	1.18	2.19	2.43	2.54
Lactic acid	692.52	814.77	2754.58	2296.82	473.85
Leucine	229.80	214.50	396.92	361.73	692.32
Maleic acid	0.92	0.07	0.66	0.01	0.01
Malic acid	12.67	29.23	15.90	10.11	6.10
Malonic acid	3.79	0.44	2.87	1.56	1.01
Malonyl-CoA Hydroxybutyryl-CoA	1064.26	817.08	226.97	692.68	74.88
Methionine	93.98	95.35	108.84	95.45	148.29
m-Hydroxybenzoic acid	1277.37	1443.22	1609.98	63.06	30384.88
N-Acetyl-alpha-D-glucosamine 1-phosphate	3165.82	1633.68	104.36	29.08	41.45
N-Acetylaspartic acid	0.96	0.64	0.50	0.86	0.29
N-Acetyl-D-glucosamine 6-phosphate	764.11	1317.80	16.99	13.46	2.67
N-Acetylglutamic acid	0.96	0.97	0.04	0.04	0.03
N-Acetylneuraminic acid	22.27	14.78	11.71	10.66	12.45
N-Carbamoyl-DL-aspartic acid	487.65	1395.34	114.44	88.66	41.51
N-Carbamyl-L-glutamic acid	0.02	0.04	0.09	0.08	0.14
N-Formyl-L-Tyrosine	405.81	343.74	172.84	125.04	1049.00
Nicotinamide	166.64	148.09	538.10	719.44	6603.50
Nicotinic acid	1191.39	646.25	788.18	767.49	224.18
Nicotinic acid mononucleotide	1012.89	649.01	3870.95	463.99	22.97
o-Hydroxybenzoic acid	32.75	37.97	44.29	39.02	34.56
O-Hydroxy hippuric acid	10298.34	8686.17	186.76	2417.40	-
O-Phospho-L-Serine	0.72	0.76	0.01	0.01	0.01
O-Phosphorylethanolamine	18.74	20.44	23.23	23.20	23.04
Orotic acid	0.49	0.92	0.07	0.08	-
O-Succinyl-L-homoserine	1442.00	2930.70	421.17	971.93	980.44
Pantothenic acid	15.14	14.68	18.73	17.13	25.17
Pentose Alcohol	0.20	0.26	1.57	1.10	0.96
Pentoses	0.85	2.46	89.71	91.61	129.80
Phenylalanine	146.67	127.91	244.79	224.25	354.28
Phenylpyruvic acid	29.21	30.75	125.81	91.91	30.10
Phosphoenolpyruvic acid	-	-	0.02	0.02	-
p-Hydroxybenzoic acid	3192.58	3666.15	10743.32	15628.45	924.79
Proline	166.39	121.00	26.06	13.82	21.03
Propionyl- CoA	923.48	124.27	728.54	330.08	72.93
Pyridoxal	0.08	0.11	0.88	0.64	0.29
Pyridoxal 5 phosphate	10.14	11.49	4.97	5.75	8.07
Pyridoxamine	6.41	5.94	5.93	5.85	5.65
Pyridoxine	1.43	2.01	15.95	14.78	21.77
Pyroglutamic acid	85.83	131.24	869.66	786.25	1089.51
Pyruvic acid	24.83	52.29	175.88	272.93	853.89
Quinic acid	-	-	0.01	2.34	0.07
Riboflavin	0.97	1.10	8.72	8.53	10.65
Ribose 5-phosphate	1.04	2.05	1.08	0.94	0.91
Ribulose 5-phosphate	1.66	2.76	0.13	0.03	-
S-5-Adenosyl-L-homocysteine	9.77	10.46	3.17	3.09	3.08
Salicylic Acid	3.14	3.65	4.25	3.75	3.32
Sedoheptulose-7-phosphate	1.17	1.17	-	-	-
Serine	96.35	103.47	29.98	26.01	59.24
Succinic acid	6.21	8.87	32.58	29.65	39.20
Taurine	281.16	420.86	7.94	3.76	14.66
Taurocholic acid	3.29	4.19	34.55	34.99	46.87
Thiamine	26.76	27.59	42.02	40.65	44.28
Threonine	478.17	457.44	130.59	110.95	112.84
Thymidine	0.07	0.09	0.45	0.30	0.65
Thymidine 5-diphosphate	1.86	1.74	-	-	-
Thymidine 5-monophosphate	2.19	2.41	2.39	2.40	2.41
Thymine	0.01	0.01	0.12	0.10	0.07
trans-4-Hydroxy-L-proline	1.58	1.78	0.37	0.39	0.05
trans-Aconitic acid	17.87	18.18	17.82	17.40	8.91
Tryptophan	173.35	136.87	155.99	135.80	211.28
Tyrosine	184.01	162.25	235.77	211.34	308.65
UDP-Glucose / UDP-Galactose	94.86	105.33	1.77	1.76	1.79
UDP-Glucuronic Acid	14.57	21.45	-	-	-
UDP-NAc Glucosamine	7474435.72	2365938.83	49.65	12.11	0.56
Uracil	0.27	0.30	2.30	1.94	1.84
Uric acid	18.77	24.62	136.75	110.88	81.27
Uridine	2.25	4.44	0.89	0.62	0.88
Uridine 5-diphosphate	28.14	26.79	-	-	-
Uridine 5-monophosphate	20.49	28.43	1.91	1.92	1.89
Uridine 5-triphosphate	447.11	308.06	391.97	85.61	0.44
Valine	218.18	182.60	229.60	209.78	332.32
Xanthine	3.45	3.96	1.02	2.15	22.82
Xanthosine	0.11	0.15	0.29	0.30	0.23
Xylulose-5-phosphate	0.68	1.45	0.15	0.06	-

Factors:

F1	Sample source:Cell lysate \| Genotype:PD-L1 KO
F2	Sample source:Cell lysate \| Genotype:Wild-type
F3	Sample source:Conditioned media \| Genotype:PD-L1 KO
F4	Sample source:Conditioned media \| Genotype:Wild-type
F5	Sample source:Culture media \| Genotype:N/A