Data for ST003604
| Metabolite structure | All data | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1-4-beta-D-Xylan | 954922.00 | 659470.62 | 242651.00 | 258406.25 | 256791.25 | 332501.75 | 438988.50 | 288020.25 | 907178.50 | 550276.00 | |
| 2/3-Phospho-D-glycerate | 79151.75 | 85926.12 | 331866.50 | 21593.25 | 115394.75 | 68778.50 | 82234.00 | 26162.50 | 78246.75 | 57015.50 | |
| 2-Hydroxyglutarate/Citramalate | 1100484.00 | 550835.00 | 473019.25 | 126611.25 | 487269.50 | 632962.75 | 414720.50 | 161221.25 | 653755.50 | 433292.00 | |
| 2-Oxoglutaramate | 19843.75 | 27927.62 | 53134.75 | 14054.00 | 31392.25 | 35132.75 | 39871.00 | 29470.25 | 27752.50 | 26202.00 | |
| 2-Oxoglutarate | 1236939.00 | 551929.25 | 108357.00 | 68735.00 | 200557.00 | 214591.25 | 476100.25 | 98379.75 | 452853.25 | 348076.75 | |
| 2-Oxoglutarate 13C5 | 24281.50 | 26286.00 | 23141.25 | 23604.00 | 25544.25 | 26351.50 | 46862.75 | 20166.00 | 26941.00 | 34915.50 | |
| 3-Phosphonooxypyruvate | 219281.75 | 212352.12 | 245155.50 | 101862.25 | 235740.50 | 205237.00 | 199178.50 | 171673.50 | 204918.75 | 174176.75 | |
| 3-Sulfino-L-alanine | 17442.75 | 15662.75 | 36561.75 | 11124.50 | 18595.75 | 22542.50 | 18117.00 | 19174.25 | 26192.00 | 18461.00 | |
| 4-Pyridoxate | 30809.75 | 23291.00 | 55552.00 | 3634.67 | 47771.25 | 44080.00 | 22526.75 | 6613.25 | 26918.50 | 28481.75 | |
| 5-L-Glutamyl-taurine | 9957.33 | 32360.75 | 248421.25 | 77654.75 | 6754.00 | 8269.75 | 99695.75 | 94325.75 | 11789.50 | 6840.75 | |
| Adenine 13C5 | - | 1961.00 | 33618.75 | 9562.67 | 56052.50 | 82866.25 | 40886.50 | 45794.50 | 122228.25 | 128414.25 | |
| Adenosine 13C5 | 5918.00 | 3803.50 | 5103.67 | - | 3823.00 | 7917.50 | 2821.50 | 3088.00 | 5179.33 | 63232.67 | |
| ADP | 383589.50 | 194376.38 | 39437.75 | 40253.25 | 212300.50 | 107093.25 | 97380.50 | 77737.25 | 211081.50 | 154948.75 | |
| ADP 13C10 | 552.00 | - | - | 408.00 | 4886.50 | 7089.00 | 1687.67 | 5771.25 | 13192.00 | 18413.25 | |
| ADP-D-ribose | 83494.50 | 45662.25 | 47115.50 | 21843.67 | 145943.25 | 148108.00 | 21223.25 | 46153.75 | 88744.75 | 46196.50 | |
| a-Linolenic acid (Octadecatrienoic acid) | 12454.25 | 11544.62 | 26552.00 | 4472.00 | 67869.50 | 48440.00 | 14742.50 | 7014.25 | 19774.00 | 14038.00 | |
| alpha-D-Glucosamine 1-phosphate | 102015.25 | 96028.38 | 104789.25 | 22700.75 | 84389.75 | 80440.50 | 84249.50 | 72399.75 | 103591.25 | 57983.75 | |
| alpha-D-Ribose 1-phosphate | 681808.75 | 922124.00 | 1282322.25 | 93119.50 | 2830397.25 | 3059185.75 | 541932.00 | 290463.00 | 1152137.50 | 532296.75 | |
| AMP 13C10 | - | 345.00 | 10983.75 | 2231.50 | 143528.75 | 159194.00 | 51042.75 | 99005.50 | 116765.75 | 207483.50 | |
| Arachidonic acid (Eicosatetraenoic acid) | 494198.00 | 808576.62 | 501662.75 | 166582.25 | 2266835.50 | 2145438.00 | 585588.75 | 239577.25 | 612004.50 | 604410.00 | |
| Ascorbate | 326192.75 | 257026.00 | 38530.75 | 4661.00 | 42711.25 | 154587.75 | 76420.75 | 5065.25 | 119748.00 | 195679.25 | |
| beta-L-Arabinose 1-phosphate | 681808.75 | 922124.00 | 1282322.25 | 93119.50 | 2830397.25 | 3059185.75 | 541932.00 | 290463.00 | 1152137.50 | 532296.75 | |
| Citrate | 2551981.25 | 1100748.62 | 1708328.25 | 241183.75 | 16413037.25 | 2248826.75 | 240193.50 | 174293.25 | 412679.50 | 230753.00 | |
| Citrate 13C1 | - | 2680.00 | 15465.33 | 2092.00 | 2653.00 | 8198.00 | 3725.67 | 3478.33 | 3899.25 | 1920.75 | |
| Citrate 13C2 | 19611.25 | 9102.00 | 57094.25 | 7976.00 | 79718.00 | 13882.50 | 7904.00 | 5419.75 | 13787.75 | 9728.25 | |
| Citrate 13C3 | 1787.50 | 4988.67 | 33697.00 | 3651.50 | 12485.67 | 4342.00 | 3458.67 | 2473.00 | 2959.50 | 3974.25 | |
| Citrate 13C4 | 5104.33 | 3281.50 | 37852.00 | 4947.50 | 59474.75 | 9993.75 | 5041.50 | 8350.75 | 4283.67 | 4807.50 | |
| CMP-N-acetylneuraminate | 63093.75 | 47818.50 | 20525.25 | 2500.50 | 52448.75 | 73019.50 | 14103.50 | 6414.75 | 42039.50 | 52585.75 | |
| D-Arabitol | 18844.25 | 15537.00 | 908559.00 | 184194.00 | 74844.25 | 80673.50 | 1245159.25 | 1146948.50 | 232956.00 | 554713.50 | |
| Dehydroascorbate | 96613.00 | 52866.12 | 59199.75 | 54875.00 | 355508.25 | 88175.25 | 97407.50 | 89442.50 | 55123.75 | 83169.50 | |
| D-Erythrose 4-phosphate | 5952.00 | 5377.33 | 13763.00 | 1721.00 | 11529.75 | 52251.25 | 8351.50 | 6061.50 | 3655.00 | 2397.50 | |
| D-Glucono-1-5-lactone 6-phosphate | 7381.75 | 9383.38 | 29118.00 | 7641.00 | 33382.75 | 114657.00 | 5559.50 | 3173.50 | 6430.50 | 8099.25 | |
| D-Glucose | 173359.50 | 112349.50 | 258425.00 | 115512.75 | 297864.00 | 254314.00 | 124515.25 | 125410.00 | 147678.50 | 216194.00 | |
| D-Glyceraldehyde 3-phosphate/Glycerone phosphate | 125732.25 | 132879.00 | 410794.50 | 125749.75 | 753210.00 | 1179678.00 | 154955.50 | 124416.75 | 125509.50 | 137602.25 | |
| Dihomo-gamma-linolenic acid ((8Z-11Z-14Z)-Icosatrienoic acid... | 156146.75 | 198501.62 | 146369.25 | 41805.75 | 542298.25 | 492735.25 | 155547.75 | 58501.25 | 174759.75 | 176876.50 | |
| Diphosphate | 6780813.25 | 8001743.50 | 8335797.00 | 5399434.00 | 11844823.50 | 8761499.50 | 8516689.50 | 6473645.25 | 11213001.25 | 8374071.50 | |
| Docosahexaenoic acid | 672529.50 | 823718.50 | 515415.75 | 140886.25 | 1341956.50 | 1109058.50 | 677842.25 | 260471.75 | 661317.25 | 591615.50 | |
| Docosapentaenoic acid ((7Z-10Z-13Z-16Z-19Z)-Docosa-7-10-13-1... | 541715.50 | 853475.50 | 313629.25 | 140574.00 | 1207230.50 | 1116366.25 | 569134.00 | 246139.25 | 572897.75 | 562703.25 | |
| Dodecanoic acid (lauric acid) | 1106260.75 | 1014272.12 | 1194334.25 | 1032639.50 | 1331040.00 | 1521798.25 | 975980.75 | 1000065.25 | 1004767.50 | 973248.00 | |
| D-Ribose | 17508.75 | 16693.88 | 21753.00 | 16133.25 | 31444.00 | 25875.75 | 18546.50 | 16438.50 | 18764.00 | 40284.25 | |
| Eicosapentaenoic acid | 134694.50 | 220063.25 | 104204.25 | 49924.00 | 312613.25 | 262293.00 | 216771.00 | 80841.50 | 106995.75 | 162619.00 | |
| Ethanolamine phosphate | 7974081.75 | 6182298.38 | 7907737.00 | 1615252.50 | 8005722.00 | 8857657.00 | 4726536.25 | 4042020.25 | 6364226.25 | 5531295.00 | |
| Fructose bisphosphate 13C6 | 629536.00 | 776995.75 | 870280.75 | 735426.50 | 680968.50 | 980473.25 | 838404.00 | 378891.25 | 798724.75 | 889905.75 | |
| Fumarate | 529847.50 | 254713.88 | 363964.00 | 176150.50 | 148142.00 | 222952.50 | 444669.75 | 188671.75 | 280816.25 | 1252299.00 | |
| Fumarate 13C4 | 368.00 | 2444.67 | 32336.25 | 4298.00 | 2027.00 | 2592.00 | 26918.75 | 16150.00 | 3469.67 | 23484.75 | |
| gamma-L-Glutamyl-L-cysteine | 116423.25 | 71387.88 | 57210.50 | 10282.75 | 133175.50 | 74630.25 | 73572.25 | 25560.50 | 100689.25 | 83005.75 | |
| Glutathione 13C10 | 67074.25 | 35093.12 | 494812.00 | 30626.00 | 271404.00 | 225691.50 | 27975.25 | 24853.00 | 37378.33 | 25592.00 | |
| Glycerol 3-phosphate | 162277.75 | 386539.25 | 874614.75 | 277085.50 | 382062.25 | 419017.25 | 535895.25 | 521138.00 | 284013.00 | 316338.50 | |
| Heptanoic acid | 431371.50 | 401678.50 | 441614.75 | 452617.00 | 424583.25 | 437297.25 | 414029.50 | 367045.25 | 370766.25 | 405093.25 | |
| Hexadecanoic acid (palmitic acid) | 28092047.50 | 26132198.75 | 28387567.50 | 23762345.00 | 26391307.50 | 28043815.00 | 25217542.50 | 25156342.50 | 25429100.00 | 24453782.50 | |
| Hexadecenoic acid (Palmitoleic acid) | 677154.75 | 553558.50 | 1714238.50 | 440874.75 | 1945245.50 | 1495089.75 | 751384.75 | 484287.75 | 836727.75 | 597567.25 | |
| Hexanoic acid (caproate) | 179956.50 | 194528.88 | 187553.75 | 185640.25 | 196460.25 | 210260.75 | 241479.25 | 227305.00 | 184966.00 | 200364.25 | |
| IMP | 313235.00 | 687427.00 | 1711805.75 | 110394.75 | 1225868.25 | 2093768.00 | 1123141.25 | 212882.00 | 418304.50 | 749202.50 | |
| Itaconate 13C3 | 5630524.00 | 4956003.75 | 4977117.75 | 2943512.75 | 5074574.25 | 2778319.25 | 5912647.00 | 5693624.25 | 3794845.00 | 3961023.75 | |
| Itaconate 13C4 | 226998.00 | 208681.50 | 233534.75 | 128078.25 | 234032.00 | 157132.75 | 288144.50 | 276657.00 | 214195.00 | 250590.00 | |
| Itaconate 13C5 | 54944.50 | 50028.62 | 52286.75 | 56548.00 | 61838.50 | 68811.25 | 71092.00 | 66921.00 | 77473.50 | 92228.00 | |
| Lactate | 5232869.50 | 10268102.38 | 31540400.00 | 2716650.50 | 11403110.75 | 14007906.00 | 16147345.25 | 3774739.50 | 6489791.50 | 12480643.00 | |
| L-Arabinose | 17508.75 | 16693.88 | 21753.00 | 16133.25 | 31444.00 | 25875.75 | 18546.50 | 16438.50 | 18764.00 | 40284.25 | |
| L-Cysteate | 67846.75 | 93264.12 | 75357.25 | 82992.75 | 83032.25 | 74496.25 | 86542.00 | 91552.75 | 90740.00 | 89320.25 | |
| Linoleic acid ((9Z,12Z)-Octadecadienoic acid) | 432545.50 | 313947.12 | 578548.50 | 121573.50 | 823472.25 | 769010.75 | 360485.75 | 170039.75 | 399199.00 | 301770.50 | |
| L-Selenomethionine | 25512.50 | 18903.25 | 13722.25 | 28993.50 | 17399.75 | 6598.75 | 5310.00 | 10684.75 | 17086.25 | 14418.50 | |
| Malate | 4021240.75 | 5160483.88 | 7193678.00 | 3214244.50 | 2558196.25 | 4267770.50 | 8390844.00 | 2974368.75 | 4828549.25 | 9215204.75 | |
| Malate 13C4 | - | - | 411449.75 | 76567.75 | 7101.25 | 25686.25 | 430469.25 | 155428.25 | 63987.25 | 341837.25 | |
| Maltose | 5215.75 | 4905.00 | 187071.00 | 5965.00 | 11101.00 | 10988.50 | 9289.50 | 9638.50 | 5330.75 | 8590.25 | |
| Mannitol | 3033257.75 | 93374.62 | 218683.00 | 142624.75 | 414225.00 | 343577.25 | 128656.00 | 497233.50 | 321360.75 | 6293877.50 | |
| N-Acetylneuraminate | 2295167.00 | 2025984.12 | 321754.75 | 41921.75 | 1885095.25 | 3667162.25 | 708995.00 | 568142.50 | 1616883.25 | 3292995.50 | |
| N-Glycoloyl-neuraminate | 124649.25 | 72314.38 | 15184.00 | 10843.67 | 80917.50 | 151523.25 | 29901.50 | 70893.75 | 106790.00 | 148958.75 | |
| N-Methylethanolamine phosphate | 88666.25 | 35347.75 | 126611.75 | 9761.00 | 95403.00 | 97404.50 | 28346.75 | 33388.50 | 38307.75 | 30446.00 | |
| Nonanoic acid (pelargonic acid) | 2154956.50 | 2100816.00 | 2340958.75 | 2106833.75 | 2378028.00 | 2452480.00 | 2147818.50 | 2094437.25 | 2099235.50 | 2165844.75 | |
| Octadecanoic acid (stearic acid) | 8836398.75 | 7662026.50 | 9630523.50 | 7158296.00 | 7652096.25 | 8558724.50 | 7443752.00 | 8333266.75 | 8710715.00 | 8196525.75 | |
| Octadecenoic acid (Oleic acid) | 4116530.50 | 2757920.25 | 6196023.50 | 1392432.50 | 8451136.00 | 7068715.50 | 3061403.50 | 2007558.75 | 4214603.75 | 2553419.75 | |
| Octanoic acid (caprylic acid) | 959973.00 | 848767.62 | 940031.50 | 916330.50 | 930918.00 | 885916.75 | 927684.00 | 787958.00 | 804332.50 | 925230.50 | |
| Pantothenol | 6069.25 | 6508.88 | 64983.00 | 1791.25 | 15445.00 | 8166.00 | 37054.00 | 11100.50 | 10127.50 | 7839.50 | |
| Phosphate | 76785857.50 | 84032992.50 | 91622027.50 | 58854187.50 | 114526007.50 | 99429042.50 | 85845285.00 | 62901370.00 | 104899235.00 | 89902077.50 | |
| Phosphoglycerate 13C3 | 22477.00 | 10541.86 | 23485.50 | 2910.00 | 53314.00 | 33105.25 | 4775.25 | 2017.00 | 25738.75 | 14434.25 | |
| Pyruvate | 514267.25 | 397798.50 | 901147.75 | 343060.50 | 350473.75 | 435881.25 | 1065339.50 | 476943.75 | 269150.25 | 375300.50 | |
| Ribose phosphate 13C5 | 4871.00 | 4219.00 | 25153.75 | 4760.33 | 116860.00 | 147127.75 | 96909.50 | 35403.50 | 88652.00 | 77234.00 | |
| (S)(+)-Allantoin | 40830.75 | 27533.00 | 40095.50 | 11655.33 | 79437.75 | 55379.50 | 25141.50 | 20353.75 | 41061.00 | 27504.75 | |
| Sedoheptulose 1-phosphate | 56856.50 | 99732.75 | 719424.50 | 83939.00 | 500408.75 | 835013.00 | 127200.75 | 39963.00 | 66784.00 | 112715.75 | |
| Sedoheptulose 1-phosphate 13C7 | 197198.25 | 185062.38 | 162534.00 | 56728.50 | 439712.25 | 381249.25 | 167483.50 | 145097.25 | 236096.25 | 195604.00 | |
| sn-glycero-3-Phosphoethanolamine | 797072.00 | 330819.75 | 1897029.50 | 138720.50 | 2196186.50 | 1859707.00 | 209937.25 | 149677.75 | 417181.75 | 248059.00 | |
| Sphingosine 1-phosphate | 9312.00 | 5829.75 | 16132.00 | 1897.33 | 13652.50 | 12431.75 | 6912.75 | 3897.25 | 7502.00 | 6608.75 | |
| Succinate | 1432715.00 | 796525.88 | 981295.75 | 148296.50 | 2701133.50 | 1903759.00 | 692266.00 | 365170.25 | 1436578.25 | 573290.50 | |
| Succinate 13C4 | 32893.25 | 28050.62 | 44727.00 | 33118.67 | 55011.25 | 42150.25 | 31503.00 | 30304.00 | 23419.00 | 33007.75 | |
| Taurine | 30655850.00 | 24394991.25 | 26529252.50 | 12307757.25 | 21029925.00 | 22880510.00 | 19701937.50 | 19055371.25 | 16978496.25 | 14534305.00 | |
| Tetradecanoic acid (myristic acid) | 2645446.00 | 2530895.50 | 3199882.25 | 2341343.25 | 3110157.50 | 2793795.50 | 2695916.75 | 2274642.50 | 2543727.75 | 2544490.75 | |
| Tetradecenoic acid (myristoleic acid) | 93822.75 | 79763.88 | 121958.75 | 58694.00 | 146896.00 | 117442.50 | 80400.00 | 58067.75 | 79173.75 | 71748.50 | |
| Thymine | 116752.75 | 115547.25 | 121047.25 | 101350.00 | 113787.50 | 118059.25 | 117752.00 | 107698.75 | 126120.50 | 113093.75 | |
| trans-4-Hydroxy-L-proline | 279503.50 | 198784.62 | 367127.75 | 74972.25 | 386522.75 | 346415.75 | 232850.50 | 159141.75 | 267929.75 | 204237.75 | |
| UDP-glucose | 101609.25 | 52566.38 | 114903.75 | 9360.50 | 67383.50 | 130378.75 | 43143.75 | 20955.75 | 85007.50 | 94404.00 | |
| UDP-N-acetyl-D-glucosamine | 162610.50 | 90769.75 | 125527.00 | 10879.25 | 141190.75 | 204090.25 | 67322.00 | 33498.75 | 125761.00 | 93901.25 | |
| UMP | 1186694.25 | 604695.12 | 1184784.00 | 60953.75 | 1376010.00 | 2214806.75 | 755515.75 | 432903.25 | 1258823.50 | 727935.75 | |
| Uracil | 136937.75 | 148786.38 | 364760.25 | 112897.25 | 175412.00 | 560212.50 | 150608.50 | 131459.00 | 142786.50 | 120119.25 | |
| Xanthine | 296234.75 | 314755.12 | 564858.25 | 39532.50 | 584091.50 | 604962.00 | 550817.75 | 158584.25 | 347590.00 | 238216.50 |
Factors:
| F1 | time (h):0 | Dead E coli treatment:no | inhibitor:none | | genotype:RagA GTP mutant |
| F2 | time (h):0 | Dead E coli treatment:no | inhibitor:none | | genotype:WT |
| F3 | time (h):18 | Dead E coli treatment:yes | inhibitor:150 nM concanamycin A | | genotype:WT |
| F4 | time (h):18 | Dead E coli treatment:yes | inhibitor:50 nM bafilomycin A1 | | genotype:WT |
| F5 | time (h):18 | Dead E coli treatment:yes | inhibitor:none | | genotype:RagA GTP mutant |
| F6 | time (h):18 | Dead E coli treatment:yes | inhibitor:none | | genotype:WT |
| F7 | time (h):6 | Dead E coli treatment:yes | inhibitor:150 nM concanamycin A | | genotype:WT |
| F8 | time (h):6 | Dead E coli treatment:yes | inhibitor:50 nM bafilomycin A1 | | genotype:WT |
| F9 | time (h):6 | Dead E coli treatment:yes | inhibitor:none | | genotype:RagA GTP mutant |
| F10 | time (h):6 | Dead E coli treatment:yes | inhibitor:none | | genotype:WT |
