Data for ST003634   

(Analysis AN005967): Average values per metabolite and experimental factor (Units:nmoles/mg dry residue protein)

Metabolite structureAll dataF1F2F3F4F5F6F7F8F9F10F11F12F13F14F15F16F17F18
Acetic acid (Ace-2_1H)
0.99 0.75 0.78 0.77 2.17 1.39 0.65 0.88 1.24 3.53 1.04 0.86 1.05 0.99 1.66 0.95 1.23 1.09
Alanine (Ala13C-B_1H)
- 8.18 14.10 - 7.35 16.88 - 9.53 11.96 - 2.90 3.32 - 3.23 3.24 - 4.50 2.30
Alanine (Ala-3_1D 1H-13C-HSQC)
- 11.31 16.73 - 8.99 19.45 - 11.58 15.26 - 3.45 4.25 - 2.95 4.33 - 4.34 3.98
Alanine (Ala-3_1H)
14.86 3.79 2.79 13.00 3.54 3.22 13.44 4.61 2.96 7.47 3.40 1.94 7.37 3.90 1.90 7.50 3.20 2.00
AMP (AMP-3^_1D 1H-13C-HSQC)
- 4.21 6.36 - 3.60 8.46 - 6.31 8.83 - 1.68 5.82 - 3.92 5.95 - 3.36 4.93
AMP (AMP-3^_1H)
21.13 16.11 11.73 18.08 10.70 11.68 16.54 13.34 20.95 27.70 25.54 13.19 19.96 15.48 12.49 22.00 16.80 16.76
Aspartic acid (Asp-3_1H)
23.07 18.41 2.28 19.71 16.46 3.22 17.62 15.91 2.56 21.10 18.35 - 18.91 18.86 - 19.73 18.18 -
ATP (ATP-3^13C-A_1H)
- - 68.54 - - 74.23 - - 71.35 - - 43.08 - - 35.00 - - 33.70
ATP (ATP-4^_1D 1H-13C-HSQC)
- 24.07 24.37 - 18.51 27.08 - 22.53 33.67 - 27.75 36.94 - 25.22 37.52 - 28.02 40.30
ATP (ATP-4^_1H)
53.87 24.60 10.54 43.01 22.51 29.47 48.52 18.13 38.38 64.74 22.88 17.04 60.60 45.64 42.32 64.05 37.24 36.78
AXP (AXP-1^ 13C-B_1H)
- 1.20 6.48 - 1.34 5.94 - 2.83 6.39 - 1.42 6.38 - 1.54 5.36 - 2.07 5.39
AXP (AXP-1^_1D 1H-13C-HSQC)
- 6.42 11.72 - 5.36 16.60 - 10.11 16.01 - 4.42 16.19 - 7.19 14.28 - 4.68 15.45
AXP (AXP-1^_1H)
34.00 25.30 20.20 29.70 22.51 22.27 27.73 21.06 26.23 38.43 30.06 20.16 34.14 29.97 21.41 33.76 26.40 21.62
AXP (AXP-2_1H)
21.50 18.51 13.61 21.18 17.19 16.15 18.41 14.50 20.66 25.88 21.69 19.38 23.51 23.91 19.59 23.80 19.00 18.69
AXP (AXP-8_1H)
34.01 30.15 23.35 30.94 26.33 28.19 28.69 24.53 31.53 43.25 34.37 26.60 37.64 34.56 28.26 37.96 30.34 28.61
Choline (Choline_1H)
1.75 1.60 2.41 1.61 1.49 2.58 1.73 1.53 2.55 0.58 0.15 - 0.38 0.25 - 0.07 - 0.30
Choline phosphate (P-Choline_1H)
68.52 54.92 62.05 55.85 47.58 65.76 55.46 45.54 72.82 100.44 85.82 109.33 88.42 87.07 115.03 89.42 82.66 113.20
Creatine (Creatine-A_1H)
38.47 33.47 21.60 34.77 29.40 25.62 34.58 28.88 24.56 28.04 22.31 16.11 24.47 23.56 17.02 25.22 20.34 16.66
Creatinine (Creatinine-P-A_1H)
8.10 7.05 7.06 7.25 6.88 7.76 8.65 5.83 9.12 2.70 2.20 2.10 2.37 2.75 2.80 2.59 2.77 2.58
Cysteine-Glutathione (Cys-GSH_1H)
50.61 42.09 29.20 43.23 40.36 30.57 46.35 41.27 30.40 48.83 41.18 27.65 43.80 40.20 28.11 45.25 37.02 28.62
Formic acid (Formate_1H)
5.89 6.12 5.22 5.98 6.07 6.49 6.58 5.39 6.65 6.37 5.81 6.31 5.93 5.88 5.38 5.83 5.79 5.97
Fumaric acid (Fumarate_1H)
0.89 0.71 0.19 0.86 0.74 0.17 0.69 0.70 0.24 0.67 0.51 0.07 0.63 0.52 - 0.67 0.53 -
Glucose (aGlc-1 13C-A_1H)
- 21.52 10.30 - 17.81 8.45 - 17.36 14.68 - 30.37 17.72 - 45.55 22.83 - 27.26 21.62
Glucose (aGlc-1_1D 1H-13C-HSQC)
- 49.73 31.18 - 44.06 31.64 - 49.47 42.41 - 66.53 50.03 - 104.38 56.55 - 61.57 49.89
Glucose (aGlc-1_1H)
23.40 - - 21.41 - - 20.27 1.56 - 34.43 1.15 - 35.68 1.75 1.64 29.37 2.92 -
Glutamic acid (Glu-3a_1D 1H-13C-HSQC)
- 0.96 5.32 - 1.37 7.53 - 2.19 8.23 - 3.78 22.26 - 2.96 17.36 - 2.76 17.23
Glutamic acid (Glu-4_1D 1H-13C-HSQC)
- 5.77 6.98 - 3.77 8.17 - 5.48 7.40 - 19.46 44.71 - 20.35 42.39 - 21.12 42.68
Glutamic acid (Glu-4_1H)
174.60 152.80 37.69 158.46 146.64 42.43 156.55 140.02 48.50 188.72 140.65 20.65 169.78 153.51 22.24 177.49 149.22 25.49
Glutathione (GSH-4_1D 1H-13C-HSQC)
- - - - - - - - - - - 10.77 - - 10.45 - 2.19 12.10
Glutathione (GSH-8_1H)
35.33 30.70 20.00 30.05 27.57 22.57 33.84 28.78 23.80 39.58 30.30 16.80 29.40 25.17 16.69 32.27 26.25 17.66
Glycine (Gly_1H)
73.12 65.08 90.17 65.55 61.53 98.52 72.54 72.05 101.56 116.98 98.79 128.31 104.32 101.84 132.45 107.07 91.28 124.18
GpC (GPC_1H)
2.53 1.76 16.14 2.11 1.38 16.15 2.24 1.37 17.28 3.79 1.40 13.53 4.59 1.64 15.70 3.77 2.14 13.21
GTP (GTP-1^ 13C-A_1H)
- - 1.82 - - 1.00 - - 2.12 - - 4.33 - - 3.27 - - 2.51
GTP (GTP_1D 1H-13C-HSQC)
- - 4.89 - - 6.28 - - 7.91 - - 10.21 - - 13.81 - 2.00 11.58
GTP (GTP_1H)
6.11 5.12 3.04 6.51 5.58 5.20 6.00 5.10 4.37 4.10 3.48 2.96 3.44 3.23 2.84 4.31 3.17 3.12
Histidine (His-5_1H)
7.38 6.98 6.36 6.67 7.18 6.56 7.49 7.91 6.71 6.69 7.25 8.85 5.61 6.95 8.72 6.31 6.18 5.72
Inosine (Inosine_1H)
2.17 1.68 3.49 2.04 2.18 4.21 2.16 1.86 5.18 2.79 1.37 5.36 1.99 1.48 5.30 1.92 1.87 5.54
Isoleucine (Ile-B_1H)
14.57 12.71 15.39 12.46 11.96 16.43 13.03 12.08 18.74 24.96 21.27 19.22 21.93 22.20 19.57 22.79 19.55 19.53
Lactic acid (Lac13C-A_1H)
- 39.44 31.29 - 34.26 37.02 - 36.34 41.75 - 30.26 28.45 - 30.06 29.00 - 29.06 27.17
Lactic acid (Lac-2_1D 1H-13C-HSQC)
- 27.54 12.88 - 24.94 17.07 - 24.23 21.27 - 23.17 12.61 - 20.45 10.12 - 21.56 11.08
Lactic acid (Lac-2_1H)
26.20 - - 24.49 - - 23.25 - - 21.38 - - 19.15 - - 19.81 - -
Lactic acid/Threonine (Lac-3/Thr_1D 1H-13C-HSQC)
- 39.44 31.29 - 34.26 37.02 - 36.34 41.75 - 30.26 28.45 - 30.06 29.00 - 29.06 27.17
Lactic acid/Threonine (Lac-3/Thr_1H)
115.66 65.50 97.94 100.81 62.87 107.39 104.03 65.30 112.06 147.23 94.36 97.49 123.72 100.59 96.70 131.55 90.92 95.71
Leucine (Leu_1H)
24.83 20.28 23.60 19.97 20.05 25.96 23.82 18.19 25.59 40.89 32.71 27.79 33.09 36.43 32.64 36.13 32.47 30.62
Methionine (Met_1H)
8.68 7.01 7.80 7.30 6.84 8.87 7.82 6.67 9.60 14.21 12.00 10.32 12.03 11.70 11.12 12.79 11.52 10.83
Myo-Inositol (m-Ins-2_1H)
111.20 101.43 114.04 98.55 99.06 127.23 103.80 101.25 131.05 54.89 51.08 55.49 50.88 53.60 57.61 51.10 47.41 59.93
NAD (NAD+-A1^_1H)
4.76 4.85 4.69 4.61 4.51 4.85 4.45 4.61 3.94 6.16 4.92 4.85 4.69 4.62 4.51 4.46 4.94 5.11
NAD (NAD+-N1^ 13C-B_1H)
- - 1.11 - - 1.46 - - 1.74 - - 1.12 - - 1.60 - - 1.53
NAD (NAD+-N1^_1D 1H-13C-HSQC)
- - 6.95 - - 8.00 - - 8.53 - 1.32 7.90 - 1.08 5.71 - 1.28 8.17
NAD (NAD+-N1^_1H)
4.94 5.09 3.03 5.09 4.55 3.11 5.06 4.62 3.68 6.19 5.45 4.37 5.11 4.79 2.80 5.32 4.92 3.29
NAD (NAD+-N2_1H)
4.56 4.44 4.91 4.70 4.54 4.85 5.19 4.62 5.20 5.89 5.44 5.19 5.36 4.48 4.23 4.90 4.72 5.06
NAD (NAD+-N6_1H)
4.30 4.81 4.86 4.48 4.63 5.10 5.05 4.59 5.51 6.44 5.45 5.49 5.60 4.67 4.40 4.67 4.80 5.34
NADP (NADP+-N2_1H)
0.84 0.65 0.60 0.79 0.60 0.67 0.94 0.58 0.70 0.92 0.54 0.54 0.70 0.58 0.72 0.61 0.55 0.51
NADP (NADP+-N6_1H)
0.74 0.70 0.50 0.94 0.63 0.74 0.95 0.69 0.90 0.81 0.63 0.75 0.79 0.69 0.35 0.69 0.49 0.53
Phenylalanine (Phe-3,5_1H)
8.65 7.64 8.62 7.52 7.40 9.29 8.04 6.83 10.38 15.54 13.27 12.07 13.47 13.23 12.44 13.75 13.17 12.57
Serine (Ser-2_1H)
70.15 41.36 59.23 40.45 35.42 66.37 50.87 46.36 73.10 85.12 60.57 41.84 65.87 60.92 45.65 65.78 60.57 45.87
Serine (Ser-3_1H)
85.70 58.94 76.39 60.52 63.39 96.61 68.83 62.87 108.82 95.09 67.54 51.57 77.78 67.40 56.50 78.42 66.15 54.84
Taurine (Tau-2 (NCH2)_1H)
68.15 59.16 52.82 61.51 59.01 62.71 60.99 57.75 61.47 33.11 35.66 29.35 33.41 25.05 30.92 35.24 32.68 34.47
Threonine (Thr_1H)
63.63 56.72 74.38 61.12 50.16 89.27 64.88 53.60 91.12 95.94 76.65 79.81 84.08 74.04 78.23 86.53 72.15 77.31
Tryptophan (Trp-4_1H)
1.23 0.98 1.13 0.72 0.88 1.30 1.13 1.07 1.15 1.82 1.50 1.88 1.69 1.31 1.60 2.00 1.27 1.52
Tyrosine (Tyr-3,5_1H)
7.39 6.04 7.59 6.33 6.13 8.60 6.65 6.68 8.80 13.93 11.85 10.41 11.55 11.46 10.29 12.01 11.04 9.81
UDP-glucose (UDP-Glc_1H)
3.57 2.84 2.08 3.92 2.63 2.24 3.96 2.36 3.80 4.56 3.63 3.65 3.01 2.39 3.23 4.08 3.24 4.06
UDP-N-acetylgalactosamine (UDP-GalNAc_1H)
1.79 1.98 0.55 2.02 2.31 1.09 1.70 2.35 1.06 1.93 3.12 1.30 1.76 2.53 1.78 2.37 3.16 1.36
UXP (UXP-1^ 13C-A_1H)
- 0.93 3.87 - - 3.65 - - 4.47 - 2.47 8.22 - 3.25 7.55 - 4.81 7.43
UXP (UXP-1^_1D 1H-13C-HSQC)
- 7.38 16.70 - 5.97 17.24 - 7.14 19.67 - 10.75 24.65 - 12.40 19.66 - 8.55 22.49
UXP (UXP-1^_1H)
19.85 13.50 11.97 19.65 13.43 14.07 16.76 13.09 17.03 19.57 14.11 9.84 21.83 16.96 11.76 20.07 14.92 11.78
UXP (UXP-5^_1H)
12.41 17.33 12.69 10.08 12.55 11.90 11.40 13.40 13.61 10.49 9.28 10.97 12.57 13.12 11.64 10.45 10.65 11.07
Valine (Val-B_1H)
15.97 13.59 18.34 12.70 12.55 20.69 14.15 12.96 21.51 28.53 23.94 23.59 24.89 25.32 24.37 25.93 23.88 24.04

Factors:

F1Genotype:P2/AP1/AP2 KO1_Gr4 | Treatment:U12C glucose | Treatment duration:30 mins
F2Genotype:P2/AP1/AP2 KO1_Gr5 | Treatment:U13C glucose | Treatment duration:30 mins
F3Genotype:P2/AP1/AP2 KO1_Gr6 | Treatment:U13C glucose | Treatment duration:5 hrs
F4Genotype:P2/AP1/AP2 KO2_Gr4 | Treatment:U12C glucose | Treatment duration:30 mins
F5Genotype:P2/AP1/AP2 KO2_Gr5 | Treatment:U13C glucose | Treatment duration:30 mins
F6Genotype:P2/AP1/AP2 KO2_Gr6 | Treatment:U13C glucose | Treatment duration:5 hrs
F7Genotype:P2/AP1/AP2 KO3_Gr4 | Treatment:U12C glucose | Treatment duration:30 mins
F8Genotype:P2/AP1/AP2 KO3_Gr5 | Treatment:U13C glucose | Treatment duration:30 mins
F9Genotype:P2/AP1/AP2 KO3_Gr6 | Treatment:U13C glucose | Treatment duration:5 hrs
F10Genotype:Wildtype1_Gr1 | Treatment:U12C glucose | Treatment duration:30 mins
F11Genotype:Wildtype1_Gr2 | Treatment:U13C glucose | Treatment duration:30 mins
F12Genotype:Wildtype1-Gr3 | Treatment:U13C glucose | Treatment duration:5 hrs
F13Genotype:Wildtype2_Gr1 | Treatment:U12C glucose | Treatment duration:30 mins
F14Genotype:Wildtype2_Gr2 | Treatment:U13C glucose | Treatment duration:30 mins
F15Genotype:Wildtype2-Gr3 | Treatment:U13C glucose | Treatment duration:5 hrs
F16Genotype:Wildtype3_Gr1 | Treatment:U12C glucose | Treatment duration:30 mins
F17Genotype:Wildtype3_Gr2 | Treatment:U13C glucose | Treatment duration:30 mins
F18Genotype:Wildtype3-Gr3 | Treatment:U13C glucose | Treatment duration:5 hrs
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