Data for ST003737
| Metabolite structure | All data | F1 | F2 | F3 | F4 |
|---|---|---|---|---|---|
| 1,3-15N2-Uric acid | 4471638.26 | 4577184.82 | 4355949.07 | 4365628.12 | |
| 13C10,15N5-Adenosine | 120328930.43 | 121834234.75 | 109241664.97 | 116784963.97 | |
| 13C3-Thiamine | 58887544.16 | 63473681.04 | 56911965.67 | 62763235.03 | |
| 13C5-Hypoxanthine | 16962406.64 | 17406298.23 | 15632057.56 | 16406728.27 | |
| 13C5-Xanthosine | 5397868.51 | 6600667.19 | 4738455.00 | 5584161.76 | |
| 15N4-Inosine | 28738895.61 | 29574546.23 | 27147325.88 | 28527279.62 | |
| 1-Methylhistidine | 1757172.17 | 1538864.27 | 1994894.46 | 1551048.17 | |
| 1-Methylnicotinamide | 16511829.55 | 19017686.68 | 20773973.36 | 16660363.48 | |
| 1-Methylxanthine | - | - | - | - | |
| 1-Methylxanthosine | - | - | - | - | |
| 2-Aminobenzoic acid | - | - | - | - | |
| 3-Hydroxybutyric acid | - | - | - | - | |
| 3-Hydroxykynurenine | - | - | - | - | |
| 3-Hydroxy-N6,N6,N6-Trimethyllysine | 3412678.49 | 4242105.83 | 4192238.13 | 5419486.40 | |
| 3-Hydroxytyrosol | 5436529.12 | 5353070.93 | 6500093.63 | 5085630.33 | |
| 3-Methoxytyrosine | - | - | - | - | |
| 3-Methylxanthine | - | - | - | - | |
| 3-Methylxanthosine | - | - | - | - | |
| 4-Hydroxyproline | - | - | - | - | |
| 4-Trimethylammoniobutanal | 15116062.63 | 14008704.44 | 14095845.39 | 12393394.40 | |
| 5-Glutamylalanine | - | - | - | - | |
| 5-Hydroxyindoleacetic acid | - | - | - | - | |
| 5-Hydroxytryptophan | 1964063.06 | 2150167.07 | 1515780.65 | 1499158.10 | |
| 5^-Methylthioadenosine | 57111567.62 | 55612676.77 | 66102881.09 | 63572591.92 | |
| 6-Aminouracil | - | - | - | - | |
| 6C13-Phenylalanine | 141954301.85 | 144205571.42 | 132881780.58 | 144231624.23 | |
| 6C13-Tyrosine | 24218170.50 | 24618470.73 | 23861917.34 | 26695969.74 | |
| 7-alpha-Hydroxy-3-oxo-4-cholestenoate | - | - | - | - | |
| 7-Methylguanine | - | - | - | - | |
| 7-Methylguanosine | - | - | - | - | |
| 7-Methylxanthine | - | - | - | - | |
| 7-Methylxanthosine | - | - | - | - | |
| 8-Hydroxy-deoxyguanosine | - | - | - | - | |
| 8-Hydroxyguanosine | 2802605.53 | 2477759.95 | 2212480.46 | 2001833.80 | |
| 8-Oxo-deoxyguanosine-13C,15N2 | - | - | - | - | |
| 9-Hexadecenoylcarnitine | 789820.77 | 740583.74 | 749228.65 | 1156753.76 | |
| Acetylcarnitine | 46784235.26 | 48043296.07 | 69876384.90 | 61760068.94 | |
| Acetylcarnitine-d3 | 448298606.75 | 456049096.40 | 423920851.87 | 442971658.83 | |
| Adenine | - | - | - | - | |
| Adenosine | 35398684.09 | 46492384.53 | 41123148.24 | 48622952.48 | |
| Adenosine diphosphate ribose | - | - | - | - | |
| Adenosylcobalamin | - | - | - | - | |
| AICA-riboside | - | - | - | - | |
| Alanine | 22805977.17 | 21597120.56 | 23320198.02 | 22336611.33 | |
| Alanine-d4 | 25434968.09 | 25206665.84 | 23272580.56 | 25345422.72 | |
| alpha-Tocopherol | 4354921.29 | 4758288.32 | 6241760.69 | 6620984.09 | |
| Arabitol | 47528966.18 | 53574653.61 | 43171278.89 | 43636350.29 | |
| Arginine | 141381235.82 | 134241929.00 | 130236140.88 | 122745367.31 | |
| Arginine-d4C13 | 184287376.60 | 188036520.70 | 184679255.80 | 192723628.98 | |
| Ascorbate | - | - | - | - | |
| Asparagine | 5944278.46 | 5850139.04 | 5670081.28 | 5721463.04 | |
| Aspartic acid | 59593952.19 | 64213088.30 | 56865914.54 | 65134998.51 | |
| Aspartic acid-d3 | 35196207.67 | 34800000.34 | 32676896.57 | 35372485.48 | |
| Asymmetric dimethylarginine | 24376391.31 | 23520942.36 | 29102317.32 | 30669348.65 | |
| Betaine | - | - | - | - | |
| Betaine-d11 | 30456752.57 | 30428905.21 | 26918940.81 | 28606859.67 | |
| Bilirubin | - | - | - | - | |
| Butyrobetaine | 18986163.49 | 21536577.09 | 24518325.64 | 27378559.73 | |
| Butyrylcarnitine | 45249663.55 | 33568350.03 | 53692538.21 | 39653961.51 | |
| Butyrylcarnitine-d3 | 252604617.27 | 250456008.90 | 228845094.58 | 247465031.00 | |
| Cadaverine | - | - | - | - | |
| cADPRibose | - | - | - | - | |
| Caffeine | - | - | - | - | |
| Capsaicin | - | - | - | - | |
| Carnitine | 48796054.14 | 49544873.54 | 56535643.04 | 57830497.29 | |
| Carnitine-d9 | 82268391.50 | 82653400.64 | 76301309.25 | 80596970.59 | |
| Choline | 236160767.13 | 228263577.18 | 252279726.03 | 239439684.00 | |
| Citrulline | - | - | - | - | |
| Citrulline-d2 | 7435662.93 | 7859154.18 | 6953866.22 | 7870018.53 | |
| Cotinine | - | - | - | - | |
| Creatine | 68768216.01 | 66586975.21 | 82212885.30 | 83202202.15 | |
| Creatinine | - | - | - | - | |
| Creatinine-d3 | - | - | - | - | |
| Curcumin | - | - | - | - | |
| Cyanocobalamin | - | - | - | - | |
| Cystathionine | - | - | - | - | |
| Cysteine | - | - | - | - | |
| Cysteinylglycine | 8374061.28 | 8772520.38 | 8357351.64 | 8572448.41 | |
| Cystine | - | - | - | - | |
| Cytosine | - | - | - | - | |
| Decanoylcarnitine | - | - | - | - | |
| Demethoxycurcumin | - | - | - | - | |
| Deoxyadenosine | - | - | - | - | |
| Deoxyguanosine | - | - | - | - | |
| Deoxyinosine | - | - | - | - | |
| Dimethylethanolamine | 11286068.54 | 10881265.78 | 9604867.20 | 11639355.54 | |
| Dimethylglycine | 15761211.51 | 15359160.49 | 20382223.35 | 16877538.91 | |
| DNL201 | - | - | - | - | |
| Dodecanoylcarnitine | 277279.50 | 386922.38 | 367797.74 | 521789.52 | |
| Dopa | - | - | - | - | |
| Dopamine | 7139424.94 | 7394193.48 | 5674917.89 | 5892022.76 | |
| Dopamine 3-o-sulfate | - | - | - | - | |
| Dopamine 4-o-sulfate | - | - | - | - | |
| Epinephrine | 9619672.94 | 9058272.80 | 8791092.05 | 8914811.70 | |
| Ergothioneine | - | - | - | - | |
| Ethanolamine | 1309628.32 | 1235225.61 | 1836540.95 | 1965292.39 | |
| Formylanthranilic acid | - | - | - | - | |
| gamma-Aminobutyric acid | 1091807.11 | 802465.39 | 1999878.84 | 1463990.32 | |
| Gamma-Glutamylcysteine | - | - | - | - | |
| Glucosamine | - | - | - | - | |
| Glucose | - | - | - | - | |
| Glutamic acid | 132643090.92 | 134304590.52 | 149013376.25 | 149100962.98 | |
| Glutamic acid-d3 | 16530876.05 | 15842779.33 | 13404111.41 | 16381321.34 | |
| Glutamine | 76259007.31 | 71862540.73 | 74608289.58 | 68150001.11 | |
| Glutathione | 55045872.76 | 49509292.52 | 78348946.79 | 54573050.40 | |
| Glutathione disulfide | - | - | - | - | |
| Glutathione-(glycine-13C2,15N) | - | - | - | - | |
| Glycerophosphocholine | 110563613.62 | 82820481.92 | 141596573.43 | 95663600.74 | |
| Glycine | 1819742.45 | 1549951.79 | 1831897.68 | 1521155.82 | |
| Guanine | 13260558.51 | 14294523.14 | 12899236.80 | 12366648.19 | |
| Guanosine | - | - | - | - | |
| Hexanoylcarnitine | 4643027.38 | 3618217.34 | 4278453.72 | 3779230.61 | |
| Histamine | - | - | - | - | |
| Histidine | 54465301.52 | 52018747.84 | 53619870.65 | 50797556.19 | |
| Homocysteine | 29081612.07 | 29386774.21 | 27066941.00 | 29839404.48 | |
| Homoserine | 21382504.55 | 19790424.98 | 20509165.07 | 19508386.51 | |
| Hydroxybutyrylcarnitine | 22162457.98 | 21812153.21 | 28995381.30 | 24409184.59 | |
| Hydroxyhexanoylcarnitine | - | - | - | - | |
| Hydroxyisovaleroyl carnitine | 23852465.58 | 21573984.48 | 33461340.52 | 25235096.68 | |
| Hydroxypropionylcarnitine | - | - | - | - | |
| Hypoxanthine | 2786683.30 | 2811406.32 | 3951769.28 | 2975687.47 | |
| Imidazoleacetic acid | 5364608.33 | 5253382.31 | 5540828.14 | 7897964.07 | |
| Indole | - | - | - | - | |
| Inosine | 7275933.83 | 8694120.48 | 8700912.40 | 7770728.42 | |
| Isovalerylcarnitine | 40018876.41 | 35673392.28 | 44434837.97 | 35782993.53 | |
| Isovalerylcarnitine-d9 | 342735902.15 | 346130908.40 | 315157097.52 | 333307948.82 | |
| Kynurenic acid | - | - | - | - | |
| Kynurenine | - | - | - | - | |
| Leucine | 102603717.63 | 99279504.84 | 93837410.97 | 95208013.61 | |
| Leucine-d3 | 138934815.88 | 140075560.32 | 132150866.55 | 140716839.95 | |
| Linoleyl carnitine | 1057678.77 | 815068.55 | 1349008.09 | 1459396.47 | |
| LPC(18:1(d7)) | 250402914.75 | 250665368.63 | 241982633.48 | 259433745.05 | |
| Lysine | 17388535.38 | 16637392.40 | 16424574.91 | 15595429.62 | |
| Mannitol | - | - | - | - | |
| Mannose | 19929533.89 | 17397474.13 | 14205200.65 | 13706908.84 | |
| Melatonin | 2691401.50 | 1566548.38 | 3407829.29 | 1987053.80 | |
| Methionine | 6382003.06 | 5798372.91 | 6695313.73 | 6161080.01 | |
| Methionine-d3 | 50541388.42 | 50704480.42 | 48538422.13 | 51874363.81 | |
| Methionine S-oxide | 4082828.46 | 3990039.25 | 3091697.22 | 3497371.90 | |
| Methylcobalamin | - | - | - | - | |
| Myristoylcarnitine | - | - | - | - | |
| Myristoylcarnitine-d9 | 66435102.23 | 68793409.31 | 70503301.49 | 67271085.73 | |
| N15C13-Glycine | 5932451.78 | 5943118.77 | 5291059.37 | 5839700.81 | |
| N1-Acetylspermidine | 8767300.79 | 6187341.17 | 13983258.31 | 7095481.39 | |
| N1-Acetylspermidine-d6 | - | - | - | - | |
| N1-Acetylspermine | - | - | - | - | |
| N1-N12-Diacetylspermine | - | - | - | - | |
| N1-N8-Diacetylspermidine | - | - | - | - | |
| N1-N8-Diacetylspermidine-d6 | - | - | - | - | |
| N6,N6,N6-Trimethyllysine | 11388760.16 | 12233314.38 | 12464845.90 | 14592333.87 | |
| N-Acetylalanine | - | - | - | - | |
| N-Acetylaspartic acid | 26522037.39 | 25078130.27 | 26045672.27 | 26251249.17 | |
| N-Acetylcysteine | - | - | - | - | |
| N-Acetylglutamic acid | - | - | - | - | |
| N-Acetylneuraminic acid | 8682120.74 | 7374375.06 | 6314543.89 | 4751195.15 | |
| N-Acetylputrescine | 487229.23 | 344774.79 | 615610.04 | 310615.74 | |
| N-Acetylserine | 6906565.38 | 6642093.30 | 9692078.52 | 8104476.07 | |
| NAD | 606784.89 | 580191.50 | 798922.84 | 816160.80 | |
| N-Alpha-acetyllysine | - | - | - | - | |
| Niacinamide | 57261344.09 | 50008459.82 | 66888397.37 | 49642708.44 | |
| Niacinamide-d4 | 382924653.30 | 391558064.28 | 375707814.75 | 392060993.03 | |
| Nicotinamide mononucleotide | - | - | - | - | |
| Nicotinamide riboside | - | - | - | - | |
| Nicotinic acid | - | - | - | - | |
| Nitrotyrosine | - | - | - | - | |
| N,N^-Bis(gamma-glutamyl)cystine | - | - | - | - | |
| Nonanoylcarnitine | - | - | - | - | |
| Norepinephrine | - | - | - | - | |
| Octanoylcarnitine | 1343324.32 | 1637649.16 | 1331546.05 | 1310871.47 | |
| Octanoylcarnitine-d3 | 183759329.28 | 187681947.08 | 165573244.05 | 174873029.33 | |
| Ornithine | 1369624.04 | 1013558.88 | 1691719.60 | 1317972.07 | |
| Ornithine-d2 | 15282286.36 | 14880748.95 | 15368280.54 | 15554369.60 | |
| Palmitoylcarnitine | 550585.66 | 573876.24 | 685580.73 | 854824.64 | |
| Palmitoylcarnitine-d3 | 30420743.16 | 30700026.70 | 30514847.24 | 31687627.53 | |
| Paraxanthine | - | - | - | - | |
| Phenylalanine | 94588326.00 | 91370134.94 | 88325682.61 | 85694035.30 | |
| Piperanine | - | - | - | - | |
| Piperine | - | - | - | - | |
| Pipernonaline | - | - | - | - | |
| Piperyline | - | - | - | - | |
| Proline | 14136130.41 | 12005736.73 | 13194208.41 | 12418593.95 | |
| Propionylcarnitine | 58466751.63 | 64388589.51 | 82007976.86 | 75704025.87 | |
| Propionylcartinine-d3 | 178186569.90 | 179119936.88 | 164654976.60 | 174546071.13 | |
| Putrescine | - | - | - | - | |
| Pyridoxamine | 14973900.45 | 15489364.12 | 11628665.56 | 12480112.81 | |
| Pyroglutamic acid | 254177437.17 | 232517706.52 | 233930840.22 | 204838234.78 | |
| S-Adenosylhomocysteine | 881879.12 | 874991.18 | 1407591.97 | 1033282.43 | |
| S-Adenosylmethionine | 11023790.85 | 10531551.23 | 17244857.41 | 13634130.92 | |
| Sarcosine | 20173620.11 | 18975551.86 | 20992820.48 | 19529089.84 | |
| Serine | 12056210.74 | 11935983.73 | 10413909.49 | 10720430.95 | |
| Serotonin | - | - | - | - | |
| Spermidine | - | - | - | - | |
| Spermine | - | - | - | - | |
| Stearoylcarnitine | - | - | - | - | |
| Sucrose | 16173511.36 | 16606858.15 | 14269459.19 | 13507499.62 | |
| Taurine | 47773323.42 | 47367114.57 | 49024788.94 | 58031413.43 | |
| Tetrahydrocurcumin | - | - | - | - | |
| Theobromine | - | - | - | - | |
| Theophylline | - | - | - | - | |
| Thiamine | 35915610.52 | 34969987.56 | 37186963.03 | 32052190.99 | |
| Threonine | 12556697.07 | 11276955.98 | 11635485.96 | 11015882.24 | |
| Trigonelline | - | - | - | - | |
| Trimethylamine-d9 N-oxide | 155032762.48 | 156631674.97 | 142157458.40 | 151055812.68 | |
| Trimethylamine-N-oxide | 7222757.93 | 7089939.34 | 6560242.46 | 7005222.91 | |
| Tryptophan | 6465561.59 | 5719550.97 | 5365019.35 | 5588825.18 | |
| Tyrosine | 6831285.34 | 6389975.09 | 6969017.27 | 6705512.59 | |
| Uracil | - | - | - | - | |
| Ureidopropionic acid | - | - | - | - | |
| Uric acid | - | - | - | - | |
| Uridine | - | - | - | - | |
| Valerobetaine | - | - | - | - | |
| Valerobetaine-d9 | 63755220.67 | 65076222.16 | 58161365.47 | 62111315.95 | |
| Valine | 5871934.41 | 5447165.37 | 6417051.25 | 7433173.20 | |
| Valine-d8 | 47773323.42 | 47367114.57 | 49024788.94 | 58031413.43 | |
| Xanthine | 2901229.16 | 2781002.63 | 2604124.32 | 2603008.27 | |
| Xanthosine | 7119616.36 | 7596448.32 | 6197057.45 | 6061007.19 |
Factors:
| F1 | genotype:PILRAKO | treatment:LPS |
| F2 | genotype:PILRAKO | treatment:Vehicle |
| F3 | genotype:WT | treatment:LPS |
| F4 | genotype:WT | treatment:Vehicle |
