Metabolomics Workbench : NIH Data Repository : Analyze Studies

Data for ST004163

(Analysis AN006908): Average values per metabolite and experimental factor (Units:normalized peak area)

Metabolite structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12	F13	F14	F15	F16	F17
1-O-Palmitoyl-Cer(d18:1/18:0)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
24-Hydroxycholesterol	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
24-Hydroxycholesterol(d7)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
3-O-SulfoLacCer(d18:1/18:0)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
4-beta-Hydroxycholesterol	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
7-keto-Cholesterol	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CE(16:1)	0.32	0.50	-	0.62	0.28	0.56	-	0.35	0.50	0.86	0.43	0.66	0.57	-	0.43	0.68	-
CE(18:1)	1.65	2.70	-	1.57	1.38	2.14	-	2.04	2.54	2.22	2.39	2.57	2.34	-	2.11	2.35	-
CE(18:1(d7))	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CE(18:2)	1.89	3.55	-	3.13	1.70	2.98	-	2.17	3.40	5.87	2.48	4.10	3.73	-	2.47	3.75	-
CE(20:4)	5.72	10.91	0.63	10.83	4.94	10.22	2.06	6.73	10.35	19.42	7.38	12.30	10.39	1.02	7.91	12.78	0.84
CE(20:5)	0.68	1.72	-	2.06	0.59	1.85	-	0.89	1.71	3.50	0.87	2.02	1.80	-	0.92	2.17	-
CE(22:6)	4.95	5.22	-	6.99	3.64	7.83	-	5.12	6.06	14.81	5.43	7.25	5.84	-	6.49	7.28	-
CE HETE	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CE HODE	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CE HpODE	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CE oxoHETE	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CE oxoODE	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Cer(d18:0/16:0)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Cer(d18:0/18:0)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Cer(d18:0/24:0)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Cer(d18:0/24:1)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Cer(d18:1/16:0)	47.91	19.32	1.22	21.99	53.12	20.05	2.04	64.54	17.59	26.01	54.19	18.68	18.21	1.44	44.29	27.06	1.25
Cer(d18:1/16:0(d7))	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Cer(d18:1/18:0)	13.91	4.31	0.05	4.54	16.23	5.38	0.07	15.40	2.55	5.77	15.90	3.60	3.46	0.06	13.67	5.73	0.06
Cer(d18:1/24:0)	12.51	14.52	0.15	3.54	15.61	7.85	0.13	18.78	9.83	1.81	10.43	12.69	12.16	0.10	20.27	9.74	0.11
Cer(d18:1/24:1)	52.87	20.96	0.84	20.54	52.47	20.20	0.94	71.84	23.73	19.49	54.81	20.75	19.18	0.93	44.32	21.66	1.47
Cholesterol	13.41	6.58	1.08	8.66	13.49	7.78	1.08	17.02	5.48	11.22	12.81	6.22	7.02	1.04	11.32	10.23	0.83
Cholesterol(d7)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Cholesteryl hexoside	0.12	0.46	0.34	0.77	0.08	0.49	2.45	0.23	0.42	2.55	0.15	0.46	0.37	1.07	0.08	1.17	0.34
Coenzyme Q10	0.01	0.01	0.01	0.01	0.00	0.01	0.01	0.01	0.01	0.02	0.01	0.01	0.01	0.01	0.00	0.02	0.01
DG(15:0/18:1(d7))	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DG(16:0_18:1)	10.76	8.82	0.27	8.78	14.11	8.82	0.34	15.42	6.65	12.40	9.29	7.91	7.66	0.28	9.85	14.28	0.28
DG(16:0_20:4)	0.12	0.34	0.14	0.44	0.18	0.47	0.15	0.16	0.26	0.48	0.13	0.28	0.29	0.11	0.11	0.37	0.07
DG(18:0_18:1)	2.51	1.11	0.01	0.76	1.94	0.85	0.02	2.80	0.63	1.20	2.18	0.86	0.81	0.02	2.42	1.57	0.02
DG(18:0_20:4)	0.35	1.05	0.46	0.67	0.44	1.06	0.43	0.58	0.73	0.82	0.46	0.76	0.70	0.37	0.34	0.74	0.32
DG(18:0_22:6)	0.07	-	0.00	-	0.09	-	0.01	0.10	-	-	0.08	-	-	0.00	0.08	-	0.00
DG(18:1/18:1)	8.02	6.45	0.15	5.21	11.14	5.24	0.37	12.80	5.91	7.42	8.03	5.55	5.27	0.25	7.52	9.22	0.29
DG(18:1_20:4)	0.08	0.28	0.22	0.30	0.12	0.33	0.21	0.11	0.20	0.31	0.08	0.22	0.21	0.19	0.07	0.24	0.17
GB3(d18:1/16:0)	0.15	0.66	0.16	1.05	0.34	1.27	0.26	0.15	0.50	1.97	0.14	0.68	0.75	0.16	0.17	2.16	0.12
GB3(d18:1/18:0)	0.04	0.12	0.01	0.22	0.09	0.32	0.03	0.02	0.07	0.36	0.04	0.12	0.13	0.02	0.04	0.31	0.02
GB3(d18:1/18:0(d3))	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GB3(d18:1/24:0)	0.02	0.21	-	0.14	0.07	0.25	-	0.02	0.17	0.13	0.03	0.25	0.26	-	0.06	0.25	-
GB3(d18:1/24:1)	0.13	0.50	0.09	1.21	0.32	1.32	0.16	0.18	0.53	1.70	0.15	0.57	0.67	0.09	0.17	1.69	0.13
GlcCer(d18:1/16:0(d3))	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
GlcCer(d18:1(d5)/18:0)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Glucosylsphingosine(d5)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HexCer(d18:1/12:0)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HexCer(d18:1/16:0)	42.08	10.80	0.88	3.46	18.61	5.02	1.02	35.11	7.13	5.01	27.56	7.31	7.50	0.78	15.40	7.44	0.52
HexCer(d18:1/18:0)	10.30	1.87	0.07	0.60	4.29	0.99	0.12	6.17	0.79	0.85	6.57	1.15	1.21	0.08	3.51	1.05	0.05
HexCer(d18:1/22:0)	13.36	2.46	0.11	0.55	4.41	0.92	0.12	11.52	1.47	0.59	10.20	1.72	1.83	0.09	4.70	1.04	0.06
HexCer(d18:1/24:0)	13.00	2.90	0.14	0.52	5.58	1.19	0.12	9.33	1.64	0.45	7.34	2.26	2.41	0.09	5.62	1.13	0.06
HexCer(d18:1/24:1)	27.16	4.17	0.61	1.65	10.88	2.19	0.75	25.17	3.32	1.89	16.90	3.11	3.25	0.63	6.79	2.27	0.73
Hexosylsphingosine	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LacCer(d18:1/16:0)	0.82	0.70	0.13	0.51	0.97	0.69	0.16	0.81	0.55	0.69	0.68	0.62	0.69	0.14	0.69	0.83	0.08
LacCer(d18:1/17:0)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LacCer(d18:1/18:0)	0.10	0.07	0.00	0.06	0.15	0.09	0.00	0.10	0.03	0.08	0.08	0.06	0.07	0.00	0.08	0.08	0.00
LacCer(d18:1/24:0)	0.05	0.05	0.00	0.02	0.08	0.05	0.00	0.06	0.04	0.01	0.04	0.06	0.07	0.00	0.06	0.04	0.00
LacCer(d18:1/24:1)	0.19	0.09	0.01	0.10	0.27	0.14	0.01	0.27	0.10	0.12	0.15	0.11	0.12	0.01	0.13	0.12	0.01
Lactosylsphingosine	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LPC(16:0)	1.56	0.93	0.02	1.20	1.25	1.16	0.03	1.45	0.68	1.38	1.37	0.88	0.86	0.03	1.30	1.46	0.02
LPC(16:1)	0.26	0.19	0.01	0.11	0.26	0.14	0.00	0.29	0.14	0.14	0.17	0.13	0.13	0.00	0.22	0.22	0.00
LPC(18:0)	0.42	0.61	0.00	0.72	0.27	0.79	0.00	0.33	0.54	0.79	0.44	0.65	0.68	0.00	0.36	0.78	0.00
LPC(18:1)	1.36	0.93	0.02	0.73	1.22	0.78	0.03	1.69	0.71	0.78	1.26	0.69	0.69	0.03	1.20	1.12	0.03
LPC(18:1(d7))	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LPC(20:4)	0.01	0.07	0.01	0.05	0.02	0.07	0.01	0.02	0.07	0.05	0.02	0.06	0.06	0.00	0.01	0.05	0.00
LPC(22:6)	0.01	0.04	-	0.02	0.01	0.03	-	0.01	0.04	0.02	0.01	0.03	0.03	-	0.01	0.03	-
LPC(24:0)	0.09	0.01	-	0.00	0.05	0.01	-	0.07	0.00	0.01	0.05	0.01	0.01	-	0.06	0.01	-
LPC(24:1)	0.04	0.01	0.00	0.00	0.03	0.00	0.00	0.05	0.00	0.01	0.03	0.01	0.01	-	0.03	0.01	-
LPC(26:0)	0.02	0.00	-	0.00	0.01	0.00	-	0.01	0.00	0.00	0.01	0.00	0.00	-	0.01	0.00	-
LPC(26:1)	0.01	0.00	-	0.00	0.01	0.00	-	0.01	0.00	0.00	0.01	0.00	0.00	-	0.01	0.00	-
lyso-GB3	0.24	0.10	-	-	0.21	0.09	-	0.20	0.09	-	0.22	0.10	0.07	-	0.15	0.10	-
lyso-GB3-d7	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
lyso-GB4	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MG(16:0)	161.10	109.59	47.86	-	182.06	105.43	44.35	160.99	105.79	-	195.22	110.19	120.91	52.25	185.93	125.47	52.88
MG(16:1)	0.28	-	-	-	0.23	-	-	0.32	-	-	0.21	-	-	-	0.25	-	-
MG(18:0)	655.36	687.93	158.80	-	702.09	672.60	171.12	667.66	654.19	-	723.74	625.72	671.14	153.21	724.77	726.32	155.19
MG(18:1)	9.23	9.82	4.41	0.72	9.61	5.08	5.34	9.26	9.16	0.64	10.32	8.94	8.52	4.62	9.88	5.50	3.86
MG(18:1(d7))	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MG(20:4)	-	-	-	0.30	-	0.65	-	-	-	0.32	-	-	-	-	-	0.25	-
N-Oleoylethanolamine	0.00	-	-	0.00	0.00	0.00	-	0.00	-	0.00	0.00	-	-	-	0.00	0.00	-
N-Palmitoyl-O-phosphocholineserine	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Palmitoylethanolamine	-	0.00	-	-	-	0.00	-	-	0.00	-	-	0.00	0.00	-	-	0.00	-
PC(15:0/18:1(d7))	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PC(16:0/5:0(CHO))	0.00	0.00	-	0.01	0.00	0.01	-	0.00	0.00	0.01	0.00	0.01	0.01	-	0.00	0.01	-
PC(16:0/9:0(CHO))	0.02	0.10	0.00	0.06	0.02	0.08	0.00	0.03	0.06	0.09	0.03	0.09	0.10	0.00	0.02	0.10	0.00
PC(16:0/9:0(COOH))	0.00	0.01	0.00	0.01	0.00	0.01	0.00	0.00	0.01	0.01	0.00	0.01	0.01	0.00	0.00	0.01	0.00
PC(18:0/20:4(OH[S]))	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PC(18:0/20:4(OOH[S]))	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PC(34:1)	9.06	10.36	3.06	11.74	8.92	10.70	2.85	9.54	9.46	12.18	8.83	9.75	9.02	2.93	8.44	11.88	2.87
PC(36:1)	5.19	4.58	0.15	4.28	4.44	4.33	0.12	5.16	3.46	5.43	5.38	4.06	3.93	0.14	4.75	5.78	0.16
PC(36:2)	9.46	10.72	0.99	11.15	9.61	10.46	1.05	10.33	9.14	12.30	9.82	9.91	9.30	1.19	8.99	12.42	1.50
PC(36:4)	1.14	2.66	0.96	3.97	1.19	3.57	0.88	1.20	2.59	3.83	1.50	2.72	2.72	0.82	0.99	2.91	0.57
PC(38:4)	0.25	0.68	0.05	1.01	0.25	0.98	0.03	0.27	0.66	0.94	0.34	0.69	0.70	0.03	0.25	0.66	0.03
PC(38:6)	0.56	1.16	-	1.02	0.62	1.15	-	0.80	1.09	1.15	0.73	1.13	1.21	-	0.46	1.19	-
PC(40:5)	0.02	-	-	0.33	0.02	0.37	-	0.02	-	0.35	0.03	-	-	-	0.02	0.33	-
PC(40:6)	0.17	0.39	-	0.35	0.15	0.41	-	0.18	0.35	0.39	0.23	0.37	0.39	-	0.16	0.38	-
PC(O-16:0/0:0)	0.01	0.01	0.00	0.01	0.01	0.01	0.00	0.01	0.01	0.01	0.01	0.01	0.01	0.00	0.01	0.01	0.00
PC(O-16:0/2:0)	0.04	0.04	0.00	0.03	0.04	0.03	0.01	0.05	0.03	0.04	0.04	0.03	0.03	0.00	0.04	0.04	0.00
PC(O-18:0/2:0)	0.01	0.01	-	0.01	0.00	0.01	-	0.01	0.01	0.01	0.01	0.01	0.01	-	0.01	0.01	-
PE(15:0/18:1(d7))	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PE(18:0/20:4(OH[S]))	-	0.05	-	-	-	0.06	-	-	0.06	-	-	0.06	0.04	-	-	0.04	-
PE(18:0/20:4(OOH[S]))	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PE(34:1)	44.20	66.55	3.74	62.04	40.63	59.70	3.89	54.86	57.41	73.41	35.53	61.73	58.62	4.07	37.32	81.16	5.12
PE(36:1)	39.45	48.90	1.15	46.08	29.83	45.22	1.13	37.32	32.33	57.61	34.62	42.76	42.47	1.32	34.08	66.18	1.95
PE(36:2)	79.36	85.94	3.38	96.44	73.44	90.85	4.28	87.16	76.12	105.56	73.27	81.61	81.12	4.84	59.04	100.40	7.38
PE(36:4)	2.84	7.95	1.47	12.33	2.48	10.73	1.59	3.45	8.27	12.96	2.31	8.31	8.69	1.25	2.39	10.56	0.83
PE(38:4)	9.52	28.40	2.95	45.34	7.16	42.95	2.54	7.67	23.32	52.67	7.99	26.94	27.24	2.08	8.99	42.46	1.61
PE(38:5)	7.91	17.72	1.67	33.86	7.46	26.94	1.72	8.68	18.30	32.46	7.32	18.16	18.58	1.62	6.31	22.19	1.68
PE(38:6)	2.85	7.07	-	8.51	2.14	6.96	-	2.99	6.93	9.13	2.44	6.67	6.74	-	2.38	8.79	-
PE(40:4)	1.38	2.86	1.13	9.64	1.11	5.04	0.62	1.33	2.23	10.53	1.18	2.42	2.62	0.71	1.21	9.72	0.67
PE(40:5)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PE(40:6)	5.70	13.76	0.78	14.80	3.83	14.34	0.51	4.04	8.64	21.14	4.57	11.52	12.57	0.60	5.24	23.75	0.66
PE(40:7)	5.30	11.58	-	14.15	4.87	12.02	-	5.54	10.35	14.82	4.90	10.59	11.12	-	4.13	13.43	-
Sitosteryl hexoside	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SM(d18:1/16:0)	13.08	11.36	3.54	14.86	14.40	13.55	3.84	16.01	10.56	16.35	13.77	10.96	10.38	3.61	11.27	14.94	3.73
SM(d18:1/18:0)	2.60	1.88	0.19	2.57	3.78	2.89	0.17	2.71	1.28	2.95	2.88	1.95	1.78	0.18	2.15	2.34	0.17
SM(d18:1/24:0)	1.54	0.63	0.07	0.66	1.83	0.76	0.04	1.92	0.52	0.51	1.37	0.69	0.71	0.04	1.32	0.62	0.04
SM(d18:1/24:1)	5.80	2.99	0.71	4.92	7.65	4.52	0.53	9.19	3.23	4.96	6.83	3.01	3.13	0.68	4.13	4.17	1.12
SM(d18:1(d9)/18:1)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Sphinganine	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Sphinganine 1-phosphate	0.02	-	-	0.01	0.03	0.01	-	0.05	-	0.01	0.02	-	-	-	0.02	0.01	-
Sphingosine	-	0.45	-	0.31	-	0.41	-	-	0.49	0.45	-	0.44	0.42	-	-	0.51	-
Sphingosine 1-phosphate	0.02	0.02	-	0.03	0.04	0.03	-	0.03	0.02	0.04	0.01	0.03	0.03	-	0.01	0.07	-
Sphingosine 1-phosphate-d7	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Sphingosine 1-phosphocholine	0.00	-	-	-	0.00	-	-	0.00	-	-	0.00	-	-	-	0.00	-	-
Sphingosine(d17:1)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TG(15:0/18:1(d7)/15:0)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TG(18:0_36:2)	0.05	0.03	-	0.04	0.03	0.03	-	0.03	0.03	0.03	0.06	0.03	0.03	-	0.05	0.04	-
TG(18:1_34:2)	0.14	0.19	0.07	1.15	0.13	0.49	0.10	0.17	0.34	0.94	0.21	0.25	0.26	0.11	0.14	0.64	0.11
TG(18:1_34:3)	0.01	0.02	0.02	0.16	0.01	0.05	0.04	0.01	0.03	0.12	0.01	0.02	0.03	0.04	0.01	0.05	0.04
TG(20:4_32:1)	0.00	0.01	-	0.04	0.00	0.02	-	0.00	0.01	0.04	0.00	0.01	0.01	-	0.00	0.02	-
TG(20:4_34:2)	0.00	0.00	-	0.03	0.00	0.01	-	0.00	0.00	0.03	0.00	0.00	0.00	-	0.00	0.01	-
TG(20:4_34:3)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TG(20:4_36:0)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TG(20:4_36:2)	0.00	0.00	-	0.03	0.00	0.01	-	0.00	0.01	0.02	0.00	0.00	0.00	-	0.00	0.01	-
TG(20:4_36:3)	0.00	-	-	0.01	0.00	0.01	-	0.00	-	0.01	0.00	-	-	-	0.00	0.01	-
TG(22:6_36:2)	0.00	0.00	-	0.01	0.00	0.01	-	0.00	0.00	0.01	0.00	0.00	0.00	-	0.00	0.01	-
TG(22:6_38:1)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TG(22:6_38:2)	0.00	-	-	-	0.00	-	-	0.00	-	-	-	-	-	-	0.00	-	-

Factors:

F1	Genotype:GBA1 KO \| Treatment:none \| Sample type:lysosome \| Sample source:HEK293
F2	Genotype:GBA1 KO \| Treatment:none \| Sample type:whole cell lysate \| Sample source:HEK293
F3	Genotype:GBA1 KO \| Treatment:none \| Sample type:whole cell lysate \| Sample source:iMG
F4	Genotype:GBA1-p.E326K \| Treatment:imiglucerase \| Sample type:whole cell lysate \| Sample source:HEK293
F5	Genotype:GBA1-p.E326K \| Treatment:none \| Sample type:lysosome \| Sample source:HEK293
F6	Genotype:GBA1-p.E326K \| Treatment:none \| Sample type:whole cell lysate \| Sample source:HEK293
F7	Genotype:GBA1-p.E326K \| Treatment:none \| Sample type:whole cell lysate \| Sample source:iMG
F8	Genotype:GBA1-p.L444P \| Treatment:none \| Sample type:lysosome \| Sample source:HEK293
F9	Genotype:GBA1-p.L444P \| Treatment:none \| Sample type:whole cell lysate \| Sample source:HEK293
F10	Genotype:NA \| Treatment:NA \| Sample type:whole cell lysate \| Sample source:HEK293
F11	Genotype:NA \| Treatment:none \| Sample type:lysosome \| Sample source:HEK293
F12	Genotype:NA \| Treatment:none \| Sample type:whole cell lysate \| Sample source:HEK293
F13	Genotype:NA \| Treatment:none \| Sample type:whole cell lysate \| Sample source:HEK294
F14	Genotype:NA \| Treatment:none \| Sample type:whole cell lysate \| Sample source:iMG
F15	Genotype:WT \| Treatment:none \| Sample type:lysosome \| Sample source:HEK293
F16	Genotype:WT \| Treatment:none \| Sample type:whole cell lysate \| Sample source:HEK293
F17	Genotype:WT \| Treatment:none \| Sample type:whole cell lysate \| Sample source:iMG