Data for ST004223
| Metabolite structure | All data | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|---|
| CAR 14:0 | - | 0.01 | - | 0.01 | - | - | - | - | |
| CAR 16:0 | 0.02 | 0.03 | 0.01 | 0.02 | - | - | - | - | |
| CAR 16:1 | - | - | - | - | - | - | - | - | |
| CAR 18:0 | - | 0.01 | 0.01 | 0.01 | - | - | - | - | |
| CAR 18:1 | 0.01 | 0.02 | 0.01 | 0.01 | - | - | - | - | |
| CAR 20:1 | - | - | - | - | - | - | - | - | |
| CAR 20:4 | - | - | - | - | - | - | - | - | |
| HexCer 18:1;O2/18:0 | 0.62 | 0.70 | 0.47 | 0.58 | 5.79 | 5.51 | 5.60 | 4.83 | |
| HexCer 18:1;O2/18:0;O | 0.48 | 0.61 | 0.43 | 0.51 | 1.74 | 1.74 | 1.54 | 1.67 | |
| HexCer 18:1;O2/20:0 | 0.17 | 0.25 | 0.15 | 0.21 | 2.13 | 2.48 | 2.08 | 2.18 | |
| HexCer 18:1;O2/20:0;O | 0.74 | 1.22 | 0.73 | 0.97 | 2.22 | 2.76 | 2.27 | 2.65 | |
| HexCer 18:1;O2/21:0;O | 0.35 | 0.57 | 0.28 | 0.51 | 1.94 | 2.31 | 2.05 | 2.23 | |
| HexCer 18:1;O2/22:0 | 0.95 | 1.36 | 0.80 | 1.28 | 9.52 | 11.53 | 9.97 | 10.11 | |
| HexCer 18:1;O2/22:0;O | 4.76 | 7.72 | 4.77 | 6.37 | 17.79 | 22.73 | 19.28 | 22.25 | |
| HexCer 18:1;O2/22:1 | 0.44 | 0.65 | 0.38 | 0.75 | 2.27 | 3.00 | 2.50 | 2.72 | |
| HexCer 18:1;O2/22:2;O | 0.37 | 0.56 | 0.30 | 0.57 | 1.26 | 1.52 | 1.36 | 1.30 | |
| HexCer 18:1;O2/23:0, 18:1;O2/22:1;O | 1.56 | 2.23 | 1.49 | 2.13 | 7.29 | 8.04 | 7.97 | 6.96 | |
| HexCer 18:1;O2/23:0;O | 3.15 | 4.53 | 3.15 | 3.95 | 10.01 | 11.31 | 10.61 | 10.68 | |
| HexCer 18:1;O2/24:0 | 2.10 | 2.77 | 1.98 | 2.80 | 23.65 | 28.79 | 25.16 | 24.41 | |
| HexCer 18:1;O2/24:0;O | 3.40 | 4.83 | 3.52 | 4.21 | 16.68 | 20.85 | 17.74 | 19.22 | |
| HexCer 18:1;O2/24:1 | 7.74 | 11.62 | 7.55 | 11.91 | 50.29 | 63.54 | 54.68 | 55.67 | |
| HexCer 18:1;O2/24:1;O, 18:1;O2/25:0 | 3.28 | 5.59 | 3.70 | 5.25 | 9.96 | 13.32 | 11.09 | 12.69 | |
| HexCer 18:1;O2/24:2 | 0.49 | 0.78 | 0.49 | 0.91 | 2.29 | 3.07 | 2.61 | 2.35 | |
| HexCer 18:1;O2/25:1, 18:1;O2/24:2;O | 0.53 | 0.83 | 0.57 | 0.89 | 1.68 | 2.09 | 1.86 | 1.89 | |
| HexCer 18:1;O2/25:1;O, 18:1;O2/26:0 | 0.14 | 0.25 | 0.18 | 0.30 | - | - | - | - | |
| LPC 14:1 | 0.16 | 0.13 | 0.18 | 0.21 | - | - | - | - | |
| LPC 16:0 | 1.22 | 1.11 | 1.39 | 1.18 | 1.66 | 1.65 | 1.85 | 1.50 | |
| LPC 18:0 | 0.44 | 0.45 | 0.46 | 0.43 | 0.72 | 0.80 | 0.80 | 0.75 | |
| LPC 18:1 | 0.57 | 0.52 | 0.62 | 0.68 | 1.18 | 1.32 | 1.27 | 1.20 | |
| LPC 20:1 | - | - | - | - | 0.11 | 0.16 | 0.12 | 0.15 | |
| LPC 20:4 | 0.13 | 0.10 | 0.14 | 0.12 | - | - | - | - | |
| LPC 22:6 | 0.11 | 0.09 | 0.14 | 0.13 | 0.14 | 0.14 | 0.16 | 0.12 | |
| LPE 16:0 | 0.29 | 0.24 | 0.30 | 0.26 | 0.50 | 0.47 | 0.56 | 0.51 | |
| LPE 16:1 | 0.50 | 0.39 | 0.54 | 0.56 | 0.61 | 0.48 | 0.67 | 0.60 | |
| LPE 18:0 | 0.57 | 0.47 | 0.61 | 0.48 | 0.70 | 0.64 | 0.90 | 0.76 | |
| LPE 18:1 | 0.76 | 1.04 | 0.82 | 1.04 | 4.18 | 4.30 | 3.90 | 3.73 | |
| LPE 18:2 | - | - | - | - | 0.06 | 0.06 | 0.06 | 0.05 | |
| LPE 20:1 | 0.13 | 0.26 | 0.14 | 0.22 | 1.06 | 1.34 | 1.05 | 1.15 | |
| LPE 20:2 | - | - | - | - | 0.07 | 0.07 | 0.05 | 0.06 | |
| LPE 20:3 | 0.04 | 0.04 | 0.04 | 0.04 | 0.09 | 0.09 | 0.07 | 0.07 | |
| LPE 20:4 | 0.70 | 0.73 | 0.68 | 0.68 | 0.83 | 0.83 | 0.74 | 0.75 | |
| LPE 22:4 | 0.27 | 0.33 | 0.25 | 0.28 | 0.50 | 0.59 | 0.41 | 0.48 | |
| LPE 22:5 | - | - | - | - | 0.04 | 0.04 | 0.03 | 0.03 | |
| LPE 22:6 | 1.29 | 1.22 | 1.45 | 1.16 | 0.79 | 0.74 | 0.69 | 0.68 | |
| LPE P-16:0 | 0.23 | 0.17 | 0.21 | 0.19 | 0.66 | 0.55 | 0.82 | 0.70 | |
| LPE P-18:0 | - | - | - | - | 0.91 | 0.79 | 1.14 | 0.96 | |
| LPE P-18:1 | 0.36 | 0.35 | 0.38 | 0.49 | 2.35 | 2.13 | 2.60 | 2.43 | |
| PC 14:0/16:0 | 0.20 | 0.23 | 0.18 | 0.20 | 0.15 | 0.14 | 0.12 | 0.14 | |
| PC 16:0/16:0 | 9.87 | 10.32 | 10.52 | 9.37 | 4.89 | 4.68 | 4.45 | 5.21 | |
| PC 16:0/18:0 | 3.07 | 3.46 | 3.18 | 2.80 | 1.76 | 1.75 | 1.64 | 1.93 | |
| PC 16:0/18:1 | 24.35 | 26.07 | 24.07 | 25.48 | 31.47 | 32.77 | 30.54 | 32.53 | |
| PC 16:0/18:2 | 1.01 | 0.95 | 0.96 | 0.90 | 1.12 | 1.16 | 1.37 | 1.14 | |
| PC 16:0/22:6, 18:2/20:4 | 5.61 | 5.42 | 5.72 | 5.75 | 6.75 | 6.43 | 7.14 | 6.40 | |
| PC 16:1/16:0, 14:1/18:0 | 1.39 | 1.40 | 1.23 | 1.19 | 1.57 | 1.35 | 1.61 | 1.40 | |
| PC 18:0/18:0 | - | - | - | - | 0.19 | 0.21 | 0.19 | 0.22 | |
| PC 18:0/18:1 | 6.69 | 8.45 | 6.24 | 8.58 | 11.77 | 13.73 | 11.24 | 13.54 | |
| PC 18:0/18:2, 18:1/18:1 | 2.78 | 3.39 | 2.61 | 3.21 | 4.63 | 5.58 | 4.78 | 5.55 | |
| PC 18:0/20:1, P-18:1/22:6 | 0.05 | 0.08 | 0.04 | 0.09 | 0.44 | 0.57 | 0.42 | 0.61 | |
| PC 18:0/20:2, P-18:2/22:6 | 0.11 | 0.20 | 0.12 | 0.19 | 0.51 | 0.70 | 0.52 | 0.74 | |
| PC 18:0/20:3 | 0.14 | 0.16 | 0.14 | 0.13 | 0.15 | 0.18 | 0.15 | 0.16 | |
| PC 18:0/22:2, 20:0/20:2 | - | - | - | - | 0.33 | 0.48 | 0.33 | 0.50 | |
| PC 18:0/22:4, 20:0/20:4, 20:2/20:2 | 0.19 | 0.21 | 0.16 | 0.19 | 0.15 | 0.18 | 0.15 | 0.16 | |
| PC 18:0/22:5 | 0.22 | 0.23 | 0.18 | 0.22 | 0.23 | 0.28 | 0.23 | 0.28 | |
| PC 18:0/22:6 | 2.61 | 2.79 | 2.60 | 2.85 | 2.86 | 2.87 | 2.82 | 2.85 | |
| PC 18:1/18:2, 16:0/20:3 | 0.44 | 0.41 | 0.38 | 0.40 | 0.40 | 0.42 | 0.47 | 0.40 | |
| PC 18:1/20:4, 16:0/22:5 | 2.03 | 2.01 | 1.71 | 1.80 | 1.19 | 1.29 | 1.30 | 1.25 | |
| PC 18:1/22:6, 18:2/22:5 | 1.09 | 1.14 | 1.08 | 1.16 | 1.20 | 1.21 | 1.25 | 1.18 | |
| PC 18:2/18:2, 16:0/20:4 | 6.44 | 5.97 | 5.36 | 5.28 | 2.72 | 2.62 | 2.91 | 2.53 | |
| PC 18:2/20:2, 18:0/20:4 | 5.54 | 5.40 | 4.42 | 4.69 | 2.34 | 2.41 | 2.26 | 2.34 | |
| PC 18:2/22:6 | - | - | - | - | 0.10 | 0.11 | 0.16 | 0.11 | |
| PC 20:0/22:1 | - | - | - | - | 0.94 | 1.04 | 0.85 | 0.97 | |
| PC 20:0/22:2, 20:2/22:0 | - | - | - | - | 0.39 | 0.48 | 0.39 | 0.47 | |
| PC 22:6/22:6 | - | - | - | - | 0.50 | 0.43 | 0.46 | 0.40 | |
| PC O-16:0/18:0 | 0.18 | 0.18 | 0.18 | 0.14 | 0.17 | 0.15 | 0.16 | 0.16 | |
| PC O-16:0/20:0 | 0.94 | 1.08 | 0.73 | 0.81 | - | - | - | - | |
| PC O-18:0/18:1, P-18:0/18:0 | 0.24 | 0.26 | 0.19 | 0.20 | 0.83 | 0.86 | 0.77 | 0.90 | |
| PC P-14:0/16:0 | 0.63 | 0.66 | 0.53 | 0.66 | 0.29 | 0.26 | 0.25 | 0.29 | |
| PC P-16:0/18:0, P-18:0/16:0, O-18:1/16:0, O-16:0/18:1 | 0.73 | 0.72 | 0.57 | 0.66 | 1.53 | 1.57 | 1.41 | 1.60 | |
| PC P-18:0/18:1, P-18:1/18:0 | - | - | - | - | 0.60 | 0.69 | 0.59 | 0.76 | |
| PC P-18:0/20:0, P-16:0/22:0 | 0.13 | 0.15 | 0.12 | 0.12 | 0.32 | 0.38 | 0.34 | 0.38 | |
| PC P-18:1/20:1, P-16:1/22:1 | 0.24 | 0.24 | 0.21 | 0.20 | 0.25 | 0.29 | 0.23 | 0.29 | |
| PC P-20:1/22:6 | - | - | - | - | 0.21 | 0.24 | 0.19 | 0.24 | |
| PC P-21:1/22:5 | - | - | - | - | 0.17 | 0.19 | 0.17 | 0.20 | |
| PC P-21:1/22:6 | - | - | - | - | 0.08 | 0.07 | 0.08 | 0.07 | |
| SM 18:1;O2/16:0 | 0.25 | 0.23 | 0.20 | 0.18 | 1.19 | 1.05 | 0.88 | 0.89 | |
| SM 18:1;O2/18:0 | 4.54 | 4.29 | 4.03 | 3.91 | 4.05 | 3.79 | 3.87 | 3.76 | |
| SM 18:1;O2/18:1 | 0.65 | 0.61 | 0.47 | 0.58 | 0.29 | 0.28 | 0.23 | 0.28 | |
| SM 18:1;O2/20:0 | 0.24 | 0.26 | 0.27 | 0.25 | 0.84 | 0.80 | 0.74 | 0.81 | |
| SM 18:1;O2/20:1 | - | - | - | - | 0.07 | 0.07 | 0.05 | 0.07 | |
| SM 18:1;O2/21:0 | - | - | - | - | 0.07 | 0.06 | 0.07 | 0.06 | |
| SM 18:1;O2/21:1 | - | - | - | - | 0.66 | 0.68 | 0.68 | 0.72 | |
| SM 18:1;O2/22:0 | 0.10 | 0.10 | 0.09 | 0.11 | 1.72 | 1.73 | 1.67 | 1.70 | |
| SM 18:1;O2/23:0 | 0.06 | 0.05 | 0.06 | 0.04 | 0.48 | 0.41 | 0.46 | 0.41 | |
| SM 18:1;O2/23:1 | - | - | - | - | 0.22 | 0.20 | 0.20 | 0.20 | |
| SM 18:1;O2/24:0 | 0.06 | 0.07 | 0.07 | 0.07 | 1.94 | 1.99 | 1.93 | 1.84 | |
| SM 18:1;O2/24:1 | 0.64 | 0.77 | 0.60 | 0.86 | 8.21 | 8.72 | 8.65 | 8.44 | |
| SM 18:1;O2/24:2 | - | - | - | - | 0.56 | 0.64 | 0.52 | 0.49 |
Factors:
| F1 | Sample source:mouse cerebrum | genotype:Cre+ |
| F2 | Sample source:mouse cerebrum | genotype:Cre- |
| F3 | Sample source:mouse cerebrum | genotype:Trem2 KO/Cre+ |
| F4 | Sample source:mouse cerebrum | genotype:Trem2 KO/Cre- |
| F5 | Sample source:mouse spinal cord | genotype:Cre+ |
| F6 | Sample source:mouse spinal cord | genotype:Cre- |
| F7 | Sample source:mouse spinal cord | genotype:Trem2 KO/Cre+ |
| F8 | Sample source:mouse spinal cord | genotype:Trem2 KO/Cre- |