Data for ST000282    Perform sample normalization    Run cluster analysis

(Analysis AN000449): Average values per metabolite and experimental factor (Units:Peak area)

Metabolite structureAll dataF1F2F3F4F5F6F7F8F9F10F11F12F13F14
2 or 3-phosphoglycerate_13C_1 ME087081 128.37 738.33 22.07 - - 357.30 837.18 462.25 790.40 326.44 466.09 - 1219.39 677.69
2 or 3-phosphoglycerate_13C_2 ME087082 460.53 - 1598.95 - 736.32 - 5485.60 - 435.52 - 1090.08 991.72 875.46 645.22
2 or 3-phosphoglycerate_13C_3 ME087083 2519.60 1673.03 1677.84 1545.60 - 1760.37 113092.75 42171.06 5351.91 1639.39 31559.43 8948.18 9539.74 2107.86
2 or 3-phosphoglycerate_2PG/3PG ME087080 103214.45 35188.93 86524.73 53821.13 238443.91 135127.87 37876.98 24628.06 146997.82 21825.66 18841.81 12978.80 99701.59 31018.40
3-Glycerophosphate ME087146 12391.26 4570.27 8902.62 4215.56 22664.44 9460.75 31766.88 33607.08 64497.73 80384.04 8523.00 4510.50 19380.74 8139.29
3-Glycerophosphate_13C_1 ME087147 1249.60 515.15 121.78 285.57 676.11 347.09 16250.86 890.48 613.11 2544.07 4665.90 2104.53 380.60 239.43
3-Glycerophosphate_13C_2 ME087148 - - - - - - - 137.22 - - - - - -
3-Glycerophosphate_13C_3 ME087149 - - - - - - - - - - - - - -
3-phosphoglyceraldehyde ME087135 11343.46 6670.17 2545.15 5968.83 16957.86 4299.17 2396.00 2247.71 6017.24 3005.04 1971.52 1095.08 2752.17 1578.31
3-phosphoglyceraldehyde_13C_1 ME087136 - - - - - - 33515.57 3038.71 - 946.22 28781.99 15828.67 1108.44 -
3-phosphoglyceraldehyde_13C_2 ME087137 - - - - - - - - - - - - - -
3-phosphoglyceraldehyde_13C_3 ME087138 - - - - - - 1952.17 5133.32 - 960.33 1871.62 1317.69 - -
6-Phosphogluconate ME087084 4160.10 5790.40 8030.98 10304.80 62055.27 8279.15 21320.16 4801.68 30785.03 4526.32 3841.24 2913.77 6784.51 4013.61
6-Phosphogluconate_13C_1 ME087085 - - - - - - - - 585.69 - - - - -
6-Phosphogluconate_13C_2 ME087086 - - - - 1184.68 - - - 862.99 - - - - -
6-Phosphogluconate_13C_3 ME087087 3.91 5.45 - - - - 20.05 4.52 - 4.26 - - - -
6-Phosphogluconate_13C_4 ME087088 0.85 1.19 - - - - 4.37 1571.89 4.75 0.93 - - - -
6-Phosphogluconate_13C_5 ME087089 9595.95 3303.80 - - 12744.48 - 2905.08 - 2464.17 - - - - -
6-Phosphogluconate_13C_6 ME087090 - - - - - - 5230.14 8358.50 - 1263.03 - - - -
Acetyl-CoA ME087091 2639.43 2907.22 1404.16 1170.02 10009.94 1977.53 2925.27 - 3873.53 10063.19 - - 1861.36 1265.54
Acetyl-CoA_13C_1 ME087092 - - - - 77.11 - - - 1228.57 - - - - -
Acetyl-CoA_13C_2 ME087093 - - - - - - 1511.89 - - - - - - -
Adenosine diphosphate_13C_1 ME087095 314.06 1043.95 1381.19 1136.58 3390.16 1412.13 803.63 4083.71 742.69 2433.33 337.86 - 879.77 457.47
Adenosine diphosphate_13C_2 ME087096 664.19 1068.59 615.11 985.07 1184.60 1437.29 3438.23 14029.62 650.05 2487.29 950.34 592.00 567.96 44.77
Adenosine diphosphate_13C_3 ME087097 - - - - - - 2193.45 13258.28 - 1353.07 911.97 - - -
Adenosine diphosphate_13C_4 ME087098 - - - - - - 2478.89 16893.74 - - - - - -
Adenosine diphosphate_13C_5 ME087099 - 928.27 4970.92 2183.70 - - 36319.72 405096.44 2345.88 11776.80 8933.26 4138.79 2974.89 -
Adenosine monophosphate_13C_1 ME087101 960.53 220.98 1966.72 488.43 1911.15 332.55 990.54 710.06 707.42 1099.36 957.57 101.86 330.10 110.94
Adenosine monophosphate_13C_2 ME087102 742.56 - 716.50 236.41 - - 762.26 2928.49 - 769.24 - - - -
Adenosine monophosphate_13C_3 ME087103 2281.15 1061.81 - - - - - 3734.09 2034.92 2407.23 - 1.51 - -
Adenosine monophosphate_13C_4 ME087104 - - - - - - 2.11 5735.90 - - 2.67 1.90 - -
Adenosine monophosphate_13C_5 ME087105 - - 1647.58 - - - 4862.06 123786.83 - 2003.69 2620.59 1996.14 - -
Adenosine triphosphate_13C_1 ME087112 - - 5124.23 335.23 - - 4844.43 5745.74 8285.37 1763.74 1758.86 379.38 4773.12 2272.83
Adenosine triphosphate_13C_2 ME087113 - - - 572.03 5432.46 6570.93 26140.87 17595.27 3029.98 1715.63 3763.32 1749.29 608.78 668.33
Adenosine triphosphate_13C_3 ME087114 4522.22 2710.61 1828.79 198.15 3562.11 2190.41 16746.40 19549.21 1821.24 921.01 2219.54 834.85 1333.09 762.20
Adenosine triphosphate_13C_4 ME087115 3583.37 1089.46 - 349.37 1476.43 794.94 10315.00 23222.39 1178.42 1126.18 1831.69 275.76 943.40 -
Adenosine triphosphate_13C_5 ME087116 4478.43 5455.62 6402.15 3458.07 1176.91 2585.11 295326.77 477969.54 6095.05 10460.58 30569.94 8287.61 18436.42 1702.71
ADP ME098373 192024.31 555865.17 142676.62 129776.29 332738.83 152596.20 64769.02 53091.93 127919.79 90286.59 36921.51 25508.99 45800.11 32560.94
AMP ME098372 103141.04 228885.09 43897.71 96393.83 73785.84 28996.47 12280.24 14554.30 21167.25 50649.05 7770.36 8995.89 14197.73 7874.64
Aspartate ME087106 548614.91 558462.39 334121.45 244325.42 392472.58 299744.10 856203.22 590574.08 337445.37 109941.24 28946.04 25213.41 33679.09 14837.25
Aspartate_13C_1 ME087107 - 39902.15 - - - - 8186.42 63329.49 - - 137.11 925.12 - -
Aspartate_13C_2 ME087108 128905.29 115926.91 42163.24 26878.29 32549.90 25250.51 40920.42 174808.67 97737.50 13259.61 3264.77 3740.44 7593.98 3698.99
Aspartate_13C_3 ME087109 64565.23 44428.53 32156.66 22299.97 33338.51 40036.16 46168.99 107896.43 141341.47 10424.67 5944.08 7001.07 13262.90 6634.86
Aspartate_13C_4 ME087110 333240.00 281764.93 136978.50 85403.72 206459.07 140738.33 1773.36 28715.75 494205.18 33076.95 1912.69 2337.05 28735.24 7881.26
ATP ME098374 3248579.73 1716871.02 852465.32 302203.57 2245329.93 1239552.38 463727.38 105649.84 980267.90 79055.52 120000.61 105575.25 358489.25 120044.09
Citrate or Isocitrate ME087117 878647.32 796921.50 1544122.93 1722315.40 1594920.90 1376227.09 1236310.69 1177438.28 1041281.09 1133463.19 1340522.99 1005508.46 977599.41 680143.00
Citrate or Isocitrate_13C_1 ME087118 88104.22 63146.26 62646.52 77895.44 15977.75 29924.81 13480.01 61755.61 33101.08 70023.31 19553.71 31997.38 55996.85 29806.27
Citrate or Isocitrate_13C_2 ME087119 169170.73 109615.11 131254.46 163593.95 83854.75 73488.04 164986.45 594901.86 99673.13 100974.04 236117.91 212028.14 120376.79 70010.04
Citrate or Isocitrate_13C_3 ME087120 92434.18 48663.79 60996.92 79466.55 78309.59 99395.49 24614.43 194675.14 99573.44 72091.93 66333.41 66689.63 205459.20 81345.90
Citrate or Isocitrate_13C_4 ME087121 394377.25 276944.83 349804.76 396105.54 519979.71 393742.60 40503.88 228734.78 345584.46 168047.81 93841.56 119105.80 249302.41 117248.96
Citrate or Isocitrate_13C_5 ME087122 50091.65 52883.58 49490.55 73069.49 71558.53 122448.56 15856.07 102853.99 142166.03 80404.85 47168.22 40785.69 590536.73 173159.10
Citrate or Isocitrate_13C_6 ME087123 8934.74 7212.49 12430.06 14254.48 29399.63 14115.34 13671.93 39068.68 16970.49 15827.75 17371.61 20873.42 21319.84 10835.77
Erythrose 4-phosphate ME087124 73818.27 - - 1923.77 53757.80 14832.13 - - 21891.74 - 3410.59 - - -
Erythrose 4-phosphate_13C_1 ME087125 - - - - 797.36 - - - - - - - - -
Erythrose 4-phosphate_13C_2 ME087126 - - 1938.26 - 1788.70 2141.03 2182.07 - 1539.29 4752.33 1190.39 1558.25 3028.84 2392.71
Erythrose 4-phosphate_13C_3 ME087127 - - - - - - 2867.69 2645.99 - - 1073.74 - - -
Erythrose 4-phosphate_13C_4 ME087128 - - - - - - - 1704.43 - - - - - -
Fructose 1,6-bisphosphate ME087027 176741.30 117378.39 71879.30 54633.81 219237.21 58899.20 33490.66 17119.20 90792.30 21792.26 13842.85 21170.16 37778.14 16893.49
Fructose 1,6-bisphosphate_13C_1 ME087129 1570.75 - - 1128.19 3194.54 600.91 80.30 540.96 389.04 - - - 422.24 -
Fructose 1,6-bisphosphate_13C_2 ME087130 1046.40 219.68 203.35 - - 392.89 284.97 - 335.50 - - - 105.97 -
Fructose 1,6-bisphosphate_13C_3 ME087131 - - - - - - 5459.63 485.18 - - 15.98 - - -
Fructose 1,6-bisphosphate_13C_4 ME087132 - - - 20.57 - - - - - 7.45 4.07 - - 5.87
Fructose 1,6-bisphosphate_13C_5 ME087133 - 3.45 2.08 1.03 7.30 - 1675.73 3343.79 3.21 0.16 - - 1.35 0.16
Fructose 1,6-bisphosphate_13C_6 ME087134 - 1639.55 4036.25 3057.21 2245.69 - 49151.17 76246.66 4854.75 7434.61 3768.82 - 4931.21 791.78
Glucose 6-phosphate or fructose-6-phosph... ME087139 98107.73 62624.03 78674.94 122910.29 197283.77 47583.61 27129.26 - 92379.79 21633.13 14578.68 13180.75 89171.05 20254.58
Glucose 6-phosphate or fructose-6-phosph... ME087140 2041.30 - 7802.74 1726.28 5337.61 658.69 197.13 - 3366.74 1849.88 2153.15 - 2275.28 2079.77
Glucose 6-phosphate or fructose-6-phosph... ME087141 803.44 962.44 - 2782.55 - - 947.29 5377.64 959.12 25022.24 2853.68 - 3670.13 1123.11
Glucose 6-phosphate or fructose-6-phosph... ME087142 - - - - - - 1404.31 - - 323.34 846.76 11.03 - -
Glucose 6-phosphate or fructose-6-phosph... ME087143 - - 21.81 - - 10.52 - - - - - 1490.69 - -
Glucose 6-phosphate or fructose-6-phosph... ME087144 2.43 1.50 1.92 - 4.04 0.46 2677.12 2.55 3.08 - 1164.76 978.74 3.69 1.29
Glucose 6-phosphate or fructose-6-phosph... ME087145 1248.57 2207.66 2160.07 - 4204.95 5268.17 72588.37 49468.37 4772.35 2886.76 33975.41 25363.23 2812.11 3117.58
Glutamate ME087150 1340134.03 1119188.67 1023551.97 819593.72 931399.86 766262.69 2747894.38 3702796.00 698649.82 944738.63 297179.63 244224.35 220797.70 178275.35
Glutamate_13C_1 ME087151 147853.16 129335.43 64237.27 38525.58 22486.98 17204.54 10841.44 187034.56 40319.83 164084.14 4737.17 3369.74 12549.84 9415.98
Glutamate_13C_2 ME087152 130146.91 96194.11 51049.62 39397.91 31799.02 29638.93 131778.06 1022554.76 57875.15 120125.61 30183.79 34966.57 17332.09 12602.63
Glutamate_13C_3 ME087153 491315.46 356413.24 243871.10 170921.00 230789.56 186131.69 15865.19 296277.32 291226.94 314819.69 7369.93 12422.56 58965.56 34684.60
Glutamate_13C_4 ME087154 40753.54 26116.95 22594.91 16039.90 42514.27 32691.63 6644.50 251734.14 58472.58 63921.14 4551.10 6978.65 - -
Glutamate_13C_5 ME087155 1491341.82 974685.84 990455.69 622575.49 1823719.47 1304054.81 4684.99 102975.44 2168848.62 1817869.50 3941.22 9069.17 261932.57 117599.99
Lactate ME087156 4447090.79 2950885.11 2907753.44 2010316.36 5563364.34 2512931.32 2251236.25 2545937.83 3709644.68 8187650.25 1864467.24 1763617.35 4331207.59 1853392.11
Lactate_13C_1 ME087157 6543.75 5447.02 25836.77 14292.76 - 1944.55 22146.00 36681.00 2139.59 - 29915.27 15110.32 4433.82 2997.12
Lactate_13C_2 ME087158 2344.38 1915.86 4002.21 - - 2224.95 28600.12 240526.20 1191.17 13837.91 31819.53 21029.50 9341.64 1467.35
Lactate_13C_3 ME087159 25420.65 15834.79 37537.71 25318.19 8206.99 6047.17 1425578.81 12758209.21 9495.55 89247.23 1287747.65 910071.49 27320.65 5628.84
Malate ME087028 716778.92 545310.98 776032.80 781070.71 965394.44 666555.25 973489.80 838119.08 324785.80 272505.41 1019920.42 680861.76 129370.15 400814.22
Malate_13C_1 ME087160 94804.73 69546.17 25500.40 38994.58 23391.05 12194.30 11124.36 85812.13 27238.05 18814.31 35126.76 48993.12 96783.54 53015.10
Malate_13C_2 ME087161 170912.99 114057.13 95790.58 91194.59 79738.39 66953.44 47269.89 251071.58 81137.14 62262.36 161017.98 107887.04 37150.60 92430.50
Malate_13C_3 ME087162 58822.62 57769.70 26195.87 27696.41 51032.77 39889.36 37073.80 132447.56 125356.59 30750.04 129374.13 107822.04 29761.80 87723.94
Malate_13C_4 ME087163 447550.13 282715.79 269293.68 220033.49 545894.78 302468.93 15125.17 55890.42 465409.77 193997.48 23201.58 32396.11 484222.28 254659.13
Malonyl-CoA ME087164 1.39 1.14 1.74 1.63 1.99 1.64 1.56 1.83 1.61 1.40 1.23 1.34 1.53 1.02
Malonyl-CoA_13C_1 ME087165 2798.16 - - - - - - - - - - - - -
Malonyl-CoA_13C_2 ME087166 - - - - - - - - - - - - - -
Malonyl-CoA_13C_3 ME087167 - - - - - - - - - - - - - -
Nicotinamide Adenine Dinucleotide oxidiz... ME087029 69566.47 70999.40 56727.30 46571.48 59189.72 38081.04 38623.29 - 72293.97 44997.10 37043.28 18072.27 120376.75 50476.54
Nicotinamide Adenine Dinucleotide oxidiz... ME087168 1401.20 1016.54 1797.63 - - 1185.17 242.01 - 531.00 1617.95 590.89 329.59 888.81 543.64
Nicotinamide Adenine Dinucleotide oxidiz... ME087169 21.33 297.76 65.04 - 98.51 243.79 3432.87 2274.38 1072.95 1195.02 3433.98 1395.79 632.46 754.87
Nicotinamide Adenine Dinucleotide oxidiz... ME087170 - 304.84 - - - - 1128.23 - - 1071.33 2095.60 1231.41 274.72 -
Nicotinamide Adenine Dinucleotide oxidiz... ME087171 - - - - - - - 1832.69 - - 1385.35 971.37 - -
Nicotinamide Adenine Dinucleotide oxidiz... ME087172 - - - - - - 19250.28 13574.72 - - 27926.80 19495.52 - -
Nicotinamide Adenine Dinucleotide reduce... ME087030 154976.16 14805.27 9660.00 2107.40 139652.23 25057.51 9261.56 - 18668.83 8172.66 1359.91 1266.62 3775.29 -
Nicotinamide Adenine Dinucleotide reduce... ME087173 111.36 634.16 - - 1364.11 2289.71 330.14 2260.77 1462.09 570.94 - - - -
Nicotinamide Adenine Dinucleotide reduce... ME087174 - 174.01 - - 1568.17 - - - - - - - - -
Nicotinamide Adenine Dinucleotide reduce... ME087175 1658.50 - - - 774.75 - 41.90 1744.58 - - - - - -
Nicotinamide Adenine Dinucleotide reduce... ME087176 - - - - - - 9.68 1940.73 - - - - - -
Nicotinamide Adenine Dinucleotide reduce... ME087177 - - - - - - 5502.05 1880.13 - - - - - -
Phosphoenolpyruvate ME087033 26161.19 15276.17 48883.76 52802.78 71738.36 71377.78 14412.10 - 58696.65 4113.03 13420.88 10894.77 68183.58 18427.89
Phosphoenolpyruvate_13C_1 ME087178 - - 56.46 - 1309.64 - 753.49 - - - - - - 153.35
Phosphoenolpyruvate_13C_2 ME087179 - - 654.71 - 868.97 - 1566.83 1975.62 - - 1347.78 805.21 711.27 -
Phosphoenolpyruvate_13C_3 ME087180 - - - - - - 42170.75 3567.35 1646.05 - 30825.73 18372.51 1299.83 -
Ribose-5-phosphate or xylulose 5-phospha... ME087181 19268.94 16465.27 42222.94 40138.01 80771.20 34807.21 14659.09 1596.62 125612.84 12976.37 3872.61 1446.42 25730.62 25455.35
Ribose-5-phosphate or xylulose 5-phospha... ME087182 - 265.28 1584.17 1078.26 2733.17 400.27 1082.14 - 563.32 328.62 - - 378.99 310.89
Ribose-5-phosphate or xylulose 5-phospha... ME087183 988.68 - - 445.91 - - 9938.31 - 2046.21 1093.69 - - - -
Ribose-5-phosphate or xylulose 5-phospha... ME087184 - - - - - - - 0.92 - - 1805.42 0.83 - -
Ribose-5-phosphate or xylulose 5-phospha... ME087185 - - - - - - - 0.22 - - - 0.20 - -
Ribose-5-phosphate or xylulose 5-phospha... ME087186 - - - - - - 66213.43 12662.64 - - 13178.94 12565.29 - -
Sedoheptulose 7-phosphate ME087187 15999.74 10482.09 30375.00 22250.96 55852.63 23152.14 7419.08 5794.15 58538.87 53609.95 4359.95 3287.67 42101.19 26672.16
Sedoheptulose 7-phosphate_13C_1 ME087188 55.30 315.59 - 178.55 891.18 - - - 379.98 - - - - 542.35
Sedoheptulose 7-phosphate_13C_2 ME087189 - - - - 3883.40 - 4879.15 - 1008.53 2729.42 1848.89 - - -
Sedoheptulose 7-phosphate_13C_3 ME087190 - - 1.43 - - - 1879.68 6.60 - - - 3.74 - -
Sedoheptulose 7-phosphate_13C_4 ME087191 - - 3215.58 - 2589.73 - 5972.90 3559.80 1785.46 - 2730.53 2673.89 - 7.73
Sedoheptulose 7-phosphate_13C_5 ME087192 - - - - - - 8286.94 - - - 3494.43 1863.94 - 884.70
Sedoheptulose 7-phosphate_13C_6 ME087193 - - - - - - 3136.40 6406.75 - - - 904.43 - -
Sedoheptulose 7-phosphate_13C_7 ME087194 - - - - - - 26498.58 29099.98 - - 12244.44 8381.99 - -
Sucrose ME087034 145515.25 117764.52 185267.72 89236.56 186140.06 176208.53 216857.09 256950.60 199220.28 382620.17 124734.92 136887.84 58983.82 106549.74
Sucrose_13C_1 ME087195 16062.42 9894.75 3619.82 3947.22 4963.79 4714.43 4366.80 17794.50 14915.12 15165.43 15396.13 9720.53 55398.82 16469.63
Sucrose_13C_2 ME087196 - - - - - - - - - - - - - -
Sucrose_13C_3 ME087197 - - - - - - - - - - - - - -
Sucrose_13C_4 ME087198 37320.35 22125.37 7765.94 17970.34 17555.79 11287.46 - 2756.01 19180.55 88263.14 - - 27565.41 14811.91

Factors:

F1Cell line:MCF10A  | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F2Cell line:MCF10A  | 13C Label:Glutamine | RhoC overexpression:yes | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F3Cell line:MDA-MB-231 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F4Cell line:MDA-MB-231 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:yes
F5Cell line:MDA-MB-231 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:yes | RhoC drug:no
F6Cell line:MDA-MB-231 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:yes | RhoC knockdown:no | RhoC drug:no
F7Cell line:SUM149 | 13C Label:Glucose | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F8Cell line:SUM149 | 13C Label:Glucose | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:yes
F9Cell line:SUM149 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F10Cell line:SUM149 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:yes
F11Cell line:SUM190 | 13C Label:Glucose | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F12Cell line:SUM190 | 13C Label:Glucose | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:yes | RhoC drug:no
F13Cell line:SUM190 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F14Cell line:SUM190 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:yes | RhoC drug:no
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