Data for ST001515
Metabolite structure | All data | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
10-heptadecenoate (17:1n7) | 1.67 | 1.15 | 1.29 | 0.28 | 1.21 | 0.85 | 2.54 | 0.88 | 1.67 | 0.50 | 1.19 | 0.99 | 1.75 | 0.84 | 0.93 | 2.36 | 1.05 | 1.60 | |
10-nonadecenoate (19:1n9) | 1.47 | 1.35 | 1.44 | 0.31 | 1.33 | 0.83 | 2.03 | 0.95 | 1.56 | 0.49 | 1.22 | 0.91 | 1.40 | 0.81 | 0.83 | 2.00 | 0.95 | 1.37 | |
10-undecenoate (11:1n1) | 1.12 | 0.78 | 1.02 | 0.61 | 0.97 | 0.86 | 1.18 | 0.85 | 1.11 | 0.88 | 1.06 | 1.01 | 1.28 | 0.93 | 0.94 | 1.67 | 1.07 | 1.07 | |
11beta-hydroxyandrosterone glucuronide | 1.05 | 1.02 | 0.90 | 1.07 | 0.88 | 0.96 | 1.44 | 1.28 | 1.21 | 1.24 | 1.20 | 1.47 | 1.40 | 1.31 | 1.34 | 0.87 | 1.39 | 1.36 | |
12,13-DiHOME | 0.94 | 1.14 | 0.82 | 0.45 | 0.89 | 0.77 | 1.14 | 1.10 | 0.95 | 0.54 | 0.89 | 0.87 | 1.03 | 1.15 | 0.83 | 1.02 | 0.74 | 0.97 | |
1,2,3-benzenetriol sulfate (2) | 0.93 | 5.95 | 1.50 | 0.53 | 1.04 | 2.31 | 0.50 | 5.79 | 0.49 | 0.35 | 0.31 | 1.44 | 0.58 | 7.20 | 0.67 | 0.53 | 1.10 | 0.80 | |
13-HODE + 9-HODE | 1.25 | 1.03 | 0.98 | 0.35 | 1.15 | 0.89 | 1.39 | 1.11 | 0.99 | 0.69 | 0.97 | 0.98 | 1.40 | 0.86 | 0.66 | 1.09 | 0.87 | 1.00 | |
(14 or 15)-methylpalmitate (a17:0 or i17:0) | 1.41 | 1.25 | 1.36 | 0.51 | 1.26 | 0.89 | 1.88 | 0.97 | 1.49 | 0.60 | 1.08 | 0.95 | 1.38 | 0.92 | 0.94 | 1.79 | 1.03 | 1.43 | |
1,5-anhydroglucitol (1,5-AG) | 1.15 | 1.11 | 0.97 | 1.09 | 0.86 | 1.13 | 1.15 | 1.04 | 0.99 | 1.16 | 0.94 | 1.14 | 0.99 | 0.98 | 1.01 | 1.00 | 0.95 | 0.95 | |
16a-hydroxy DHEA 3-sulfate | 0.97 | 1.25 | 1.17 | 1.16 | 1.13 | 1.27 | 1.74 | 1.68 | 1.32 | 1.52 | 1.53 | 1.61 | 1.40 | 1.60 | 1.48 | 1.50 | 1.47 | 1.21 | |
16-hydroxypalmitate | 1.14 | 1.08 | 1.12 | 0.57 | 0.98 | 0.91 | 1.22 | 1.02 | 1.20 | 0.74 | 1.09 | 1.02 | 1.11 | 0.87 | 0.91 | 1.37 | 0.98 | 0.96 | |
(16 or 17)-methylstearate (a19:0 or i19:0) | 1.34 | 1.35 | 1.49 | 0.54 | 1.46 | 0.88 | 1.72 | 1.01 | 1.48 | 0.67 | 1.26 | 0.91 | 1.21 | 0.94 | 0.95 | 1.56 | 1.12 | 1.35 | |
1-carboxyethylphenylalanine | 1.22 | 0.78 | 0.75 | 1.03 | 0.74 | 1.27 | 1.21 | 0.70 | 0.79 | 0.99 | 0.84 | 1.37 | 1.29 | 1.67 | 1.51 | 0.93 | 1.27 | 1.49 | |
1-carboxyethylvaline | 1.05 | 0.63 | 0.54 | 0.85 | 0.59 | 1.09 | 0.95 | 0.57 | 0.59 | 0.72 | 0.54 | 1.03 | 0.98 | 1.46 | 1.27 | 0.78 | 1.01 | 1.20 | |
1H-indole-7-acetic acid | 0.64 | 0.47 | 0.56 | 0.57 | 0.79 | 0.70 | 0.72 | 0.67 | 0.84 | 0.53 | 0.97 | 0.79 | 0.90 | 1.04 | 0.84 | 0.69 | 0.70 | 0.86 | |
1-linoleoyl-GPA (18:2)* | 1.03 | 0.89 | 0.78 | 0.56 | 0.68 | 0.96 | 1.01 | 0.88 | 0.77 | 0.61 | 0.79 | 1.08 | 1.05 | 0.96 | 1.00 | 0.80 | 0.96 | 1.37 | |
1-linoleoyl-GPG (18:2)* | 1.12 | 1.13 | 0.77 | 1.22 | 0.74 | 0.88 | 1.14 | 1.02 | 0.79 | 1.16 | 0.77 | 0.94 | 0.95 | 1.40 | 0.95 | 1.04 | 0.99 | 1.25 | |
1-palmitoyl-GPG (16:0)* | 1.03 | 0.89 | 0.55 | 1.08 | 0.61 | 0.68 | 1.00 | 0.71 | 0.68 | 0.84 | 0.53 | 0.63 | 0.69 | 0.80 | 0.78 | 0.73 | 0.68 | 1.24 | |
1-stearoyl-GPS (18:0)* | 0.84 | 0.79 | 0.70 | 1.83 | 0.34 | 0.43 | 0.47 | 0.37 | 0.65 | 0.93 | 0.36 | 0.49 | 0.71 | 0.56 | 0.58 | 0.35 | 0.39 | 0.38 | |
21-hydroxypregnenolone disulfate | 1.02 | 1.10 | 0.91 | 1.08 | 0.97 | 0.99 | 1.24 | 1.06 | 0.97 | 1.27 | 1.05 | 1.23 | 1.11 | 1.05 | 1.09 | 0.97 | 1.14 | 1.05 | |
2,3-dihydroxy-2-methylbutyrate | 0.73 | 0.52 | 0.52 | 0.76 | 0.54 | 0.85 | 0.61 | 0.66 | 0.58 | 0.77 | 0.55 | 1.10 | 0.71 | 0.70 | 0.70 | 0.60 | 0.68 | 0.95 | |
2,3-dihydroxy-5-methylthio-4-pentenoate (DMTPA)* | 0.99 | 0.85 | 0.96 | 0.95 | 0.91 | 0.96 | 1.08 | 0.86 | 0.95 | 1.03 | 1.01 | 1.09 | 1.17 | 1.29 | 1.14 | 1.10 | 1.18 | 1.19 | |
2,3-diphosphoglycerate | 0.27 | 0.03 | 0.08 | 0.03 | 0.03 | 0.08 | 1.65 | 0.03 | 0.03 | 0.20 | 0.11 | 0.03 | 0.03 | 0.08 | 0.03 | 3.78 | 0.68 | 1.24 | |
2,6-dihydroxybenzoic acid | 0.86 | 1.25 | 0.57 | 0.76 | 0.57 | 1.45 | 1.20 | 1.42 | 0.67 | 0.91 | 0.71 | 1.66 | 1.16 | 2.56 | 1.41 | 0.87 | 1.37 | 1.51 | |
2-acetamidophenol sulfate | 0.62 | 1.33 | 0.61 | 0.33 | 1.05 | 1.30 | 0.63 | 1.51 | 0.62 | 0.32 | 1.27 | 1.14 | 0.63 | 2.54 | 0.79 | 0.39 | 1.90 | 1.44 | |
2-aminophenol sulfate | 0.79 | 1.49 | 0.63 | 0.37 | 1.31 | 1.73 | 1.06 | 1.80 | 0.78 | 0.47 | 1.58 | 1.72 | 0.93 | 3.08 | 1.11 | 0.48 | 2.63 | 1.52 | |
2-hydroxy-3-methylvalerate | 1.06 | 1.22 | 1.26 | 0.71 | 1.19 | 1.00 | 1.04 | 1.07 | 1.28 | 0.75 | 1.21 | 1.02 | 1.19 | 1.16 | 1.23 | 0.99 | 1.09 | 1.11 | |
2-hydroxyacetaminophen sulfate* | 0.02 | 0.14 | 0.21 | 0.43 | 0.27 | 0.02 | 0.46 | 0.59 | 0.66 | 0.27 | 0.74 | 0.17 | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | |
2-hydroxyarachidate* | 1.26 | 1.61 | 1.16 | 0.99 | 1.32 | 0.95 | 1.57 | 1.21 | 1.41 | 0.86 | 0.92 | 0.85 | 1.02 | 1.25 | 0.93 | 1.20 | 1.23 | 1.68 | |
2-hydroxybehenate | 1.08 | 1.33 | 1.17 | 0.86 | 1.20 | 0.92 | 1.21 | 1.15 | 1.23 | 0.90 | 1.01 | 0.97 | 1.02 | 1.08 | 0.93 | 1.17 | 0.97 | 1.31 | |
2-hydroxydecanoate | 1.21 | 1.11 | 0.96 | 0.52 | 0.98 | 1.26 | 0.88 | 1.04 | 0.87 | 0.53 | 0.91 | 1.13 | 1.17 | 1.33 | 1.01 | 1.13 | 1.08 | 1.55 | |
2-hydroxynervonate* | 1.22 | 1.41 | 1.24 | 0.75 | 1.39 | 0.91 | 1.35 | 1.13 | 1.34 | 0.87 | 1.08 | 0.90 | 1.06 | 1.12 | 0.94 | 1.36 | 1.07 | 1.44 | |
2-hydroxyoctanoate | 1.14 | 1.39 | 0.85 | 0.81 | 0.88 | 1.22 | 0.98 | 1.17 | 0.80 | 0.86 | 0.83 | 0.98 | 1.23 | 1.94 | 1.24 | 1.13 | 1.19 | 1.41 | |
2-hydroxypalmitate | 1.30 | 1.46 | 1.50 | 1.00 | 1.38 | 0.90 | 1.31 | 1.08 | 1.42 | 0.93 | 0.99 | 0.85 | 1.10 | 1.06 | 1.00 | 1.30 | 0.98 | 1.34 | |
2-hydroxyphenylacetate | 0.79 | 1.47 | 1.22 | 0.91 | 1.25 | 0.97 | 0.94 | 1.30 | 1.13 | 0.77 | 1.38 | 0.97 | 1.00 | 0.92 | 0.86 | 0.93 | 0.97 | 0.97 | |
2-hydroxyphytanate* | 1.54 | 1.19 | 1.14 | 1.29 | 0.91 | 1.11 | 1.52 | 1.05 | 1.16 | 1.02 | 0.73 | 1.00 | 1.23 | 1.21 | 1.10 | 1.46 | 0.87 | 1.78 | |
2-hydroxystearate | 1.15 | 1.32 | 1.32 | 0.97 | 1.31 | 0.86 | 1.18 | 1.09 | 1.40 | 0.97 | 1.00 | 0.89 | 1.05 | 1.08 | 1.03 | 1.20 | 1.03 | 1.29 | |
2-methoxyacetaminophen glucuronide* | 0.07 | 0.16 | 0.17 | 0.18 | 0.19 | 0.07 | 0.15 | 0.16 | 0.17 | 0.10 | 0.18 | 0.16 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | |
2-methoxyacetaminophen sulfate* | 0.36 | 0.36 | 0.43 | 0.42 | 0.42 | 0.36 | 0.41 | 0.45 | 0.44 | 0.36 | 0.47 | 0.38 | 0.36 | 0.36 | 0.36 | 0.36 | 0.36 | 0.36 | |
2-naphthol sulfate | 2.42 | 1.84 | 1.88 | 2.08 | 1.51 | 2.61 | 0.70 | 0.69 | 0.59 | 0.55 | 0.47 | 0.74 | 1.08 | 0.91 | 0.86 | 0.94 | 0.75 | 1.33 | |
(2 or 3)-decenoate (10:1n7 or n8) | 1.48 | 1.03 | 1.03 | 0.34 | 1.06 | 0.78 | 1.27 | 0.81 | 0.98 | 0.46 | 1.19 | 0.89 | 1.34 | 1.14 | 0.99 | 1.47 | 1.27 | 0.88 | |
3-(3-hydroxyphenyl)propionate | 0.94 | 1.20 | 1.08 | 0.55 | 1.15 | 1.16 | 0.62 | 1.17 | 0.71 | 0.51 | 0.66 | 1.24 | 0.76 | 0.82 | 0.72 | 0.58 | 1.22 | 0.93 | |
3-(4-hydroxyphenyl)lactate (HPLA) | 1.24 | 0.88 | 0.86 | 0.88 | 0.84 | 1.16 | 1.20 | 0.82 | 1.03 | 0.97 | 0.99 | 1.28 | 1.20 | 1.34 | 1.29 | 1.07 | 1.18 | 1.27 | |
3,4-methyleneheptanoate | 1.04 | 1.93 | 1.15 | 0.82 | 0.97 | 0.58 | 1.12 | 1.80 | 1.53 | 0.80 | 0.86 | 0.81 | 1.07 | 2.06 | 0.82 | 0.96 | 1.10 | 0.46 | |
3beta-hydroxy-5-cholestenoate | 1.45 | 1.13 | 1.05 | 1.10 | 0.99 | 0.89 | 1.58 | 1.08 | 1.31 | 1.12 | 0.94 | 0.89 | 1.16 | 1.12 | 1.02 | 1.37 | 1.02 | 1.27 | |
3-bromo-5-chloro-2,6-dihydroxybenzoic acid* | 1.09 | 1.11 | 0.99 | 1.09 | 1.02 | 0.95 | 1.26 | 1.16 | 1.26 | 1.30 | 1.09 | 1.11 | 0.90 | 0.86 | 0.91 | 0.88 | 0.81 | 0.94 | |
3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP) | 0.94 | 0.99 | 1.09 | 0.86 | 1.00 | 1.03 | 0.98 | 1.01 | 1.06 | 0.92 | 1.02 | 1.05 | 1.29 | 1.41 | 1.24 | 1.16 | 1.13 | 1.41 | |
3-carboxy-4-methyl-5-propyl-2-furanpropanoate (CMPF) | 2.02 | 1.58 | 1.81 | 1.80 | 1.62 | 1.90 | 1.78 | 1.68 | 1.67 | 1.86 | 1.17 | 1.81 | 4.07 | 4.18 | 3.98 | 3.88 | 3.39 | 4.08 | |
3-hydroxy-2-ethylpropionate | 1.02 | 0.97 | 1.10 | 0.70 | 0.98 | 0.92 | 1.05 | 0.89 | 1.14 | 0.78 | 1.05 | 1.09 | 1.27 | 1.26 | 1.24 | 1.36 | 1.18 | 1.20 | |
3-hydroxybutyroylglycine | 0.61 | 0.85 | 0.84 | 0.54 | 0.91 | 0.66 | 0.76 | 0.92 | 1.32 | 0.65 | 1.21 | 0.77 | 1.05 | 1.03 | 0.71 | 1.51 | 1.04 | 0.93 | |
3-hydroxydecanoate | 1.25 | 1.21 | 1.11 | 0.45 | 1.20 | 0.90 | 1.22 | 0.91 | 1.13 | 0.56 | 1.19 | 0.93 | 1.26 | 0.92 | 0.88 | 1.47 | 1.02 | 0.90 | |
3-hydroxyhexanoate | 0.93 | 1.44 | 1.30 | 0.48 | 1.45 | 0.80 | 1.04 | 1.10 | 1.23 | 0.66 | 1.35 | 0.88 | 1.14 | 1.09 | 0.87 | 1.48 | 1.12 | 1.10 | |
3-hydroxylaurate | 1.26 | 1.00 | 1.09 | 0.54 | 1.22 | 0.82 | 1.25 | 0.87 | 1.15 | 0.67 | 1.24 | 0.95 | 1.31 | 0.88 | 0.92 | 1.41 | 1.05 | 0.91 | |
3-hydroxyoctanoate | 1.08 | 1.51 | 1.14 | 0.43 | 1.13 | 0.85 | 1.08 | 1.09 | 1.12 | 0.61 | 1.13 | 0.89 | 1.19 | 1.01 | 0.90 | 1.51 | 1.08 | 0.95 | |
3-hydroxyoleate* | 1.32 | 0.80 | 1.20 | 0.60 | 1.11 | 0.90 | 1.62 | 0.90 | 1.15 | 0.57 | 1.04 | 0.91 | 1.15 | 0.99 | 0.96 | 1.46 | 0.96 | 1.14 | |
3-hydroxypyridine sulfate | 0.64 | 0.83 | 0.51 | 0.47 | 0.44 | 0.69 | 1.19 | 1.12 | 0.75 | 1.05 | 0.69 | 2.21 | 0.62 | 1.32 | 0.59 | 0.56 | 0.63 | 1.05 | |
3-indoleglyoxylic acid | 0.68 | 0.98 | 1.06 | 1.01 | 0.94 | 0.64 | 0.64 | 1.28 | 0.92 | 0.89 | 0.75 | 0.73 | 0.51 | 0.45 | 0.54 | 0.47 | 0.56 | 0.57 | |
3-indoxyl sulfate | 1.49 | 1.20 | 0.80 | 1.22 | 0.61 | 1.17 | 1.10 | 1.22 | 0.78 | 1.02 | 0.69 | 1.07 | 1.19 | 1.76 | 1.18 | 1.01 | 0.94 | 1.26 | |
3-methoxycatechol sulfate (1) | 1.17 | 3.20 | 1.18 | 0.44 | 0.77 | 1.19 | 0.62 | 2.49 | 0.61 | 0.30 | 0.67 | 1.09 | 0.75 | 3.53 | 1.01 | 0.40 | 1.54 | 0.75 | |
3-methyl-2-oxobutyrate | 1.08 | 1.16 | 1.02 | 0.85 | 0.88 | 1.00 | 1.02 | 1.10 | 1.14 | 0.93 | 1.07 | 0.97 | 1.09 | 1.03 | 1.02 | 1.12 | 1.03 | 0.94 | |
3-methyl-2-oxovalerate | 1.06 | 1.31 | 1.21 | 0.57 | 1.09 | 0.96 | 0.92 | 1.15 | 1.18 | 0.66 | 1.16 | 0.90 | 1.08 | 1.13 | 1.09 | 1.04 | 1.07 | 1.03 | |
3-(methylthio)acetaminophen sulfate* | 0.08 | 0.09 | 0.17 | 0.16 | 0.24 | 0.08 | 0.39 | 0.39 | 0.40 | 0.36 | 0.44 | 0.20 | 0.14 | 0.12 | 0.10 | 0.12 | 0.10 | 0.18 | |
3-methylxanthine | 0.69 | 0.63 | 0.65 | 0.63 | 0.65 | 0.75 | 0.67 | 0.63 | 0.63 | 0.63 | 0.63 | 1.17 | 0.67 | 0.63 | 0.63 | 0.66 | 0.63 | 0.98 | |
3-(N-acetyl-L-cystein-S-yl) acetaminophen | 0.03 | 0.17 | 0.13 | 0.12 | 0.13 | 0.03 | 0.24 | 0.18 | 0.22 | 0.10 | 0.21 | 0.16 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | |
3-phenylpropionate (hydrocinnamate) | 1.61 | 1.11 | 1.30 | 1.09 | 1.04 | 1.64 | 1.18 | 1.55 | 1.20 | 0.97 | 1.50 | 1.62 | 1.01 | 1.60 | 1.06 | 0.80 | 0.99 | 1.45 | |
4-acetamidobutanoate | 1.12 | 0.93 | 0.72 | 0.94 | 0.77 | 1.05 | 1.01 | 0.87 | 0.91 | 0.94 | 0.85 | 1.15 | 1.20 | 1.14 | 1.20 | 1.08 | 1.25 | 1.15 | |
4-acetamidophenylglucuronide | 0.00 | 0.13 | 0.10 | 0.28 | 0.11 | 0.01 | 0.19 | 0.23 | 0.21 | 0.10 | 0.24 | 0.13 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
4-acetaminophen sulfate | 0.01 | 0.34 | 0.15 | 3.53 | 0.14 | 0.06 | 3.26 | 4.33 | 4.37 | 1.62 | 4.84 | 1.46 | 0.02 | 0.01 | 0.01 | 0.02 | 0.01 | 0.06 | |
4-allylcatechol sulfate | 1.33 | 1.17 | 0.64 | 0.58 | 0.95 | 2.13 | 1.19 | 1.19 | 1.22 | 0.59 | 1.65 | 2.40 | 0.69 | 1.11 | 0.76 | 0.32 | 1.39 | 2.36 | |
4-allylphenol sulfate | 1.49 | 0.77 | 1.21 | 1.21 | 0.57 | 0.85 | 1.53 | 0.88 | 1.21 | 1.35 | 0.74 | 1.35 | 1.60 | 0.95 | 1.65 | 1.34 | 1.02 | 0.98 | |
4-ethylcatechol sulfate | 1.75 | 0.90 | 1.78 | 1.30 | 1.86 | 1.23 | 0.83 | 1.34 | 1.00 | 0.69 | 0.99 | 1.05 | 1.02 | 1.75 | 1.32 | 0.75 | 1.19 | 1.33 | |
4-ethylphenyl sulfate | 5.71 | 4.14 | 6.27 | 8.07 | 6.94 | 3.74 | 0.97 | 1.44 | 2.41 | 1.24 | 2.27 | 0.22 | 1.75 | 2.52 | 3.51 | 1.80 | 2.68 | 1.68 | |
4-hydroxychlorothalonil | 1.08 | 0.97 | 1.01 | 1.09 | 1.00 | 0.94 | 1.28 | 1.20 | 1.26 | 1.34 | 1.16 | 1.13 | 1.00 | 0.99 | 0.97 | 0.97 | 0.92 | 1.07 | |
4-hydroxyhippurate | 1.31 | 1.20 | 0.90 | 0.62 | 1.04 | 1.44 | 1.17 | 1.08 | 0.76 | 0.61 | 1.36 | 1.81 | 1.28 | 1.89 | 1.41 | 0.94 | 2.15 | 1.69 | |
4-hydroxyphenylacetate | 0.76 | 0.50 | 0.37 | 0.42 | 0.53 | 0.45 | 0.72 | 0.55 | 0.58 | 0.67 | 0.71 | 0.83 | 0.77 | 1.01 | 0.75 | 0.53 | 0.79 | 1.26 | |
4-hydroxyphenylpyruvate | 1.14 | 0.95 | 0.92 | 1.16 | 0.86 | 1.17 | 1.04 | 0.88 | 0.92 | 1.07 | 0.93 | 1.06 | 0.99 | 1.16 | 1.11 | 0.94 | 1.03 | 1.03 | |
4-methoxyphenol sulfate | 0.98 | 2.01 | 0.83 | 0.67 | 0.51 | 1.40 | 1.03 | 2.14 | 0.81 | 0.66 | 0.49 | 1.25 | 1.07 | 2.85 | 1.10 | 0.64 | 0.80 | 1.55 | |
4-methyl-2-oxopentanoate | 1.05 | 1.25 | 1.16 | 0.62 | 1.08 | 0.94 | 0.94 | 1.14 | 1.25 | 0.71 | 1.22 | 0.92 | 1.07 | 1.05 | 1.04 | 1.07 | 1.03 | 1.00 | |
4-methylbenzenesulfonate | 1.05 | 0.89 | 1.14 | 0.96 | 1.01 | 0.93 | 1.04 | 0.98 | 0.99 | 0.99 | 0.98 | 1.06 | 1.10 | 0.96 | 1.02 | 1.04 | 1.08 | 0.99 | |
4-methylcatechol sulfate | 1.02 | 2.22 | 0.88 | 0.73 | 0.71 | 1.47 | 0.83 | 3.02 | 1.01 | 0.73 | 0.95 | 1.46 | 1.02 | 3.38 | 1.09 | 0.80 | 1.24 | 1.78 | |
4-methylguaiacol sulfate | 0.78 | 2.73 | 0.60 | 0.52 | 0.52 | 1.06 | 0.78 | 3.46 | 0.97 | 0.59 | 0.73 | 1.21 | 0.97 | 4.31 | 0.94 | 0.80 | 0.87 | 1.41 | |
4-vinylphenol sulfate | 1.12 | 1.60 | 1.18 | 0.80 | 0.73 | 0.72 | 0.98 | 1.64 | 1.22 | 0.74 | 0.81 | 0.56 | 1.25 | 2.11 | 1.60 | 0.88 | 1.20 | 0.81 | |
5,6-dihydrothymine | 1.12 | 0.84 | 0.92 | 1.13 | 0.84 | 1.10 | 1.11 | 0.88 | 1.04 | 1.05 | 0.80 | 1.00 | 1.02 | 1.10 | 0.95 | 1.09 | 1.02 | 1.16 | |
5,6-dihydrouracil | 0.83 | 0.58 | 0.93 | 0.67 | 0.88 | 0.91 | 1.02 | 0.69 | 0.83 | 0.88 | 0.82 | 0.91 | 0.72 | 0.87 | 0.76 | 0.99 | 0.53 | 0.72 | |
5,6-dihydrouridine | 1.14 | 0.86 | 0.79 | 0.97 | 0.73 | 1.14 | 1.11 | 0.83 | 0.86 | 1.06 | 0.78 | 1.17 | 1.13 | 1.18 | 1.16 | 1.16 | 1.13 | 1.18 | |
5alpha-androstan-3alpha,17beta-diol monosulfate (1) | 1.16 | 0.95 | 0.67 | 1.02 | 0.72 | 1.23 | 1.88 | 1.08 | 0.99 | 1.79 | 0.77 | 2.09 | 1.33 | 1.38 | 1.16 | 1.46 | 1.15 | 1.24 | |
5alpha-androstan-3alpha,17beta-diol monosulfate (2) | 0.50 | 0.46 | 0.43 | 0.44 | 0.36 | 0.45 | 0.84 | 0.74 | 0.77 | 0.79 | 0.72 | 0.75 | 1.43 | 1.58 | 1.40 | 1.41 | 1.32 | 1.31 | |
5alpha-androstan-3beta,17alpha-diol disulfate | 0.71 | 0.61 | 0.56 | 0.77 | 0.53 | 0.72 | 1.16 | 1.08 | 0.93 | 1.16 | 0.89 | 1.23 | 1.06 | 1.35 | 1.06 | 1.04 | 1.19 | 0.89 | |
5alpha-androstan-3beta,17beta-diol disulfate | 1.37 | 1.27 | 1.20 | 1.43 | 1.11 | 1.48 | 1.61 | 1.34 | 1.18 | 1.73 | 0.99 | 1.79 | 1.59 | 1.85 | 1.65 | 1.57 | 1.58 | 1.53 | |
5alpha-androstan-3beta,17beta-diol monosulfate (2) | 0.70 | 0.58 | 0.50 | 0.65 | 0.46 | 0.68 | 1.03 | 0.59 | 0.49 | 1.00 | 0.45 | 1.12 | 0.81 | 0.80 | 0.79 | 0.89 | 0.80 | 0.78 | |
5alpha-pregnan-3beta,20alpha-diol disulfate | 4.72 | 1.24 | 2.57 | 4.44 | 2.10 | 4.09 | 2.89 | 3.53 | 3.61 | 3.36 | 2.94 | 2.55 | 1.50 | 2.05 | 1.77 | 1.57 | 2.61 | 1.24 | |
5alpha-pregnan-3beta,20alpha-diol monosulfate (2) | 4.25 | 0.88 | 1.83 | 4.94 | 1.38 | 3.19 | 2.52 | 3.19 | 3.20 | 2.90 | 2.26 | 2.35 | 1.42 | 1.80 | 1.37 | 1.68 | 2.40 | 1.18 | |
5alpha-pregnan-3beta,20beta-diol monosulfate (1) | 2.57 | 1.14 | 1.61 | 2.60 | 1.24 | 2.18 | 3.11 | 2.83 | 3.70 | 3.28 | 2.91 | 2.63 | 1.51 | 1.99 | 1.59 | 1.95 | 2.49 | 1.20 | |
5alpha-pregnan-diol disulfate | 0.76 | 0.45 | 0.56 | 1.08 | 0.57 | 0.78 | 1.15 | 1.17 | 1.44 | 1.48 | 1.10 | 0.87 | 0.47 | 0.64 | 0.48 | 0.57 | 0.97 | 0.37 | |
5-dodecenoate (12:1n7) | 1.42 | 0.81 | 1.07 | 0.34 | 1.10 | 0.88 | 1.73 | 0.85 | 1.35 | 0.60 | 1.28 | 1.16 | 1.41 | 0.75 | 0.88 | 1.54 | 0.96 | 0.94 | |
5-methyluridine (ribothymidine) | 1.09 | 1.07 | 1.03 | 0.99 | 1.01 | 1.05 | 0.97 | 0.92 | 0.94 | 0.91 | 0.94 | 0.97 | 1.05 | 1.05 | 1.07 | 1.02 | 1.09 | 1.04 | |
5-oxoproline | 1.16 | 0.73 | 0.64 | 1.23 | 0.60 | 1.16 | 1.19 | 0.73 | 0.79 | 1.03 | 0.77 | 1.18 | 1.18 | 1.16 | 1.15 | 1.15 | 1.15 | 1.19 | |
6-bromotryptophan | 1.20 | 0.81 | 0.69 | 1.20 | 0.60 | 1.11 | 1.15 | 0.93 | 0.81 | 1.23 | 0.74 | 1.13 | 1.09 | 1.15 | 1.10 | 1.04 | 1.09 | 1.08 | |
6-hydroxyindole sulfate | 1.48 | 1.26 | 0.78 | 1.17 | 0.62 | 1.17 | 1.06 | 1.28 | 0.76 | 0.96 | 0.68 | 1.03 | 1.23 | 1.95 | 1.18 | 1.05 | 0.97 | 1.30 | |
6-oxopiperidine-2-carboxylate | 1.25 | 1.10 | 0.85 | 1.55 | 0.86 | 1.26 | 1.08 | 0.77 | 0.87 | 1.04 | 0.85 | 1.26 | 1.14 | 0.92 | 1.05 | 1.13 | 1.02 | 1.14 | |
7-HOCA | 1.28 | 0.85 | 0.88 | 0.97 | 0.83 | 1.09 | 1.21 | 0.93 | 0.97 | 1.14 | 0.91 | 1.25 | 1.13 | 0.94 | 1.04 | 1.30 | 1.10 | 1.18 | |
9,10-DiHOME | 0.87 | 1.34 | 0.79 | 0.49 | 0.80 | 0.74 | 0.90 | 1.21 | 0.95 | 0.59 | 0.76 | 0.78 | 0.98 | 1.38 | 0.71 | 0.92 | 0.69 | 0.77 | |
9-hydroxystearate | 1.22 | 0.87 | 1.10 | 0.25 | 0.88 | 0.94 | 1.71 | 1.14 | 1.47 | 0.60 | 0.99 | 1.19 | 1.30 | 0.89 | 0.85 | 1.29 | 0.86 | 1.17 | |
acesulfame | 0.73 | 0.73 | 0.73 | 0.73 | 0.73 | 0.90 | 0.73 | 0.73 | 0.73 | 0.73 | 0.73 | 0.81 | 0.73 | 0.73 | 0.73 | 0.73 | 0.73 | 0.73 | |
acisoga | 0.85 | 0.56 | 0.52 | 0.79 | 0.55 | 0.88 | 0.96 | 0.61 | 0.69 | 0.92 | 0.67 | 1.27 | 1.01 | 1.10 | 1.09 | 0.99 | 1.16 | 1.15 | |
aconitate [cis or trans] | 1.04 | 1.02 | 1.11 | 0.78 | 1.06 | 0.95 | 1.02 | 0.94 | 1.07 | 0.79 | 0.98 | 1.02 | 1.08 | 0.97 | 1.07 | 1.02 | 1.02 | 1.10 | |
ADpSGEGDFXAEGGGVR* | 0.26 | 0.26 | 0.27 | 0.26 | 0.26 | 0.46 | 0.33 | 0.26 | 0.26 | 0.26 | 1.53 | 0.59 | 0.34 | 0.31 | 0.32 | 2.13 | 0.26 | 1.01 | |
adrenate (22:4n6) | 1.57 | 1.39 | 1.34 | 0.75 | 1.27 | 0.84 | 1.91 | 1.02 | 1.50 | 0.72 | 1.14 | 0.94 | 1.55 | 1.08 | 1.05 | 2.18 | 1.04 | 1.51 | |
ADSGEGDFXAEGGGVR* | 0.24 | 0.24 | 0.34 | 0.24 | 0.30 | 0.73 | 0.36 | 0.24 | 0.26 | 0.24 | 0.97 | 1.19 | 0.43 | 0.35 | 0.36 | 4.94 | 0.24 | 1.07 | |
alpha-hydroxycaproate | 1.10 | 0.51 | 0.61 | 0.64 | 0.48 | 0.80 | 0.79 | 0.41 | 0.62 | 0.58 | 0.69 | 0.62 | 0.43 | 0.74 | 0.62 | 0.45 | 0.49 | 0.81 | |
alpha-hydroxyisocaproate | 1.10 | 1.19 | 1.21 | 0.69 | 1.11 | 1.03 | 1.05 | 1.04 | 1.30 | 0.71 | 1.25 | 1.00 | 1.12 | 1.17 | 1.21 | 1.03 | 1.04 | 1.07 | |
androstenediol (3alpha, 17alpha) monosulfate (2) | 1.03 | 0.94 | 0.72 | 1.33 | 0.79 | 1.12 | 1.34 | 0.97 | 0.94 | 1.04 | 1.00 | 1.44 | 1.13 | 0.92 | 1.02 | 0.78 | 1.14 | 1.07 | |
androstenediol (3alpha, 17alpha) monosulfate (3) | 1.20 | 1.28 | 1.11 | 1.20 | 1.20 | 1.06 | 1.34 | 1.17 | 1.10 | 1.42 | 1.08 | 1.28 | 0.99 | 1.00 | 0.96 | 0.97 | 0.92 | 0.93 | |
androstenediol (3beta,17beta) disulfate (1) | 1.13 | 1.18 | 1.08 | 1.29 | 1.03 | 1.33 | 1.38 | 1.14 | 1.03 | 1.50 | 0.95 | 1.56 | 1.13 | 1.26 | 1.07 | 1.13 | 1.06 | 1.12 | |
androstenediol (3beta,17beta) disulfate (2) | 1.08 | 1.03 | 0.87 | 1.19 | 0.93 | 1.17 | 1.30 | 1.04 | 1.01 | 1.37 | 1.05 | 1.39 | 1.17 | 1.14 | 1.11 | 1.15 | 1.16 | 1.09 | |
androstenediol (3beta,17beta) monosulfate (1) | 1.06 | 1.13 | 0.88 | 1.13 | 0.87 | 1.11 | 1.49 | 1.12 | 1.01 | 1.59 | 0.96 | 1.57 | 1.20 | 1.14 | 1.05 | 1.30 | 1.10 | 1.14 | |
androstenediol (3beta,17beta) monosulfate (2) | 1.16 | 1.04 | 1.07 | 1.19 | 1.03 | 1.46 | 1.81 | 1.32 | 1.35 | 1.70 | 0.99 | 2.03 | 1.42 | 1.53 | 1.35 | 1.36 | 1.32 | 1.44 | |
andro steroid monosulfate C19H28O6S (1)* | 0.58 | 0.60 | 0.66 | 0.79 | 0.66 | 0.72 | 0.85 | 0.62 | 0.60 | 0.79 | 0.60 | 0.84 | 0.84 | 0.83 | 0.85 | 0.86 | 0.78 | 0.75 | |
androsterone glucuronide | 0.97 | 0.95 | 0.89 | 1.05 | 0.96 | 1.01 | 1.15 | 0.91 | 0.94 | 0.99 | 0.94 | 1.19 | 1.30 | 1.21 | 1.25 | 1.08 | 1.36 | 1.23 | |
androsterone sulfate | 1.15 | 0.96 | 0.82 | 1.13 | 0.85 | 1.15 | 1.66 | 1.00 | 0.92 | 1.65 | 0.82 | 1.73 | 1.43 | 1.40 | 1.35 | 1.42 | 1.35 | 1.32 | |
arachidate (20:0) | 1.14 | 1.48 | 1.25 | 0.93 | 1.18 | 0.92 | 1.23 | 1.12 | 1.15 | 0.88 | 0.97 | 0.89 | 1.11 | 1.18 | 1.00 | 1.24 | 1.03 | 1.27 | |
arachidonate (20:4n6) | 1.48 | 1.16 | 1.21 | 1.07 | 1.22 | 0.76 | 1.41 | 1.00 | 1.33 | 0.87 | 0.96 | 0.73 | 1.32 | 1.21 | 1.09 | 1.61 | 1.09 | 1.27 | |
behenate (22:0)* | 1.11 | 1.69 | 1.28 | 0.79 | 1.05 | 0.97 | 1.06 | 1.22 | 0.94 | 0.83 | 0.85 | 0.87 | 1.06 | 1.20 | 1.01 | 1.06 | 1.00 | 1.24 | |
benzoate | 0.97 | 1.01 | 0.91 | 1.00 | 1.02 | 1.02 | 1.08 | 0.98 | 0.96 | 1.00 | 1.17 | 1.07 | 0.99 | 0.91 | 1.08 | 1.16 | 1.16 | 1.09 | |
beta-citrylglutamate | 1.21 | 0.95 | 0.98 | 1.20 | 0.82 | 1.07 | 1.14 | 0.86 | 0.94 | 1.22 | 0.69 | 1.09 | 1.21 | 0.98 | 1.12 | 1.01 | 1.07 | 1.12 | |
beta-hydroxyisovalerate | 1.03 | 1.16 | 1.27 | 0.68 | 1.39 | 0.96 | 1.40 | 1.23 | 1.56 | 1.00 | 1.51 | 1.34 | 1.06 | 1.05 | 0.96 | 0.93 | 0.88 | 1.04 | |
bilirubin | 1.17 | 0.72 | 0.81 | 1.16 | 0.76 | 0.95 | 1.20 | 1.25 | 1.27 | 1.39 | 1.11 | 0.95 | 1.29 | 1.11 | 1.23 | 1.32 | 1.16 | 1.14 | |
bilirubin (E,E)* | 1.17 | 0.62 | 0.74 | 0.84 | 0.89 | 0.96 | 1.24 | 0.88 | 1.18 | 1.00 | 1.21 | 1.15 | 1.38 | 0.81 | 0.94 | 1.46 | 1.02 | 1.11 | |
branched chain 14:0 dicarboxylic acid | 1.13 | 1.16 | 0.90 | 0.91 | 0.66 | 1.47 | 0.90 | 1.47 | 0.99 | 0.78 | 1.21 | 1.41 | 1.06 | 1.21 | 0.86 | 0.91 | 1.29 | 1.40 | |
branched-chain fatty acid 18:0 (2) | 1.15 | 1.18 | 1.17 | 0.93 | 1.05 | 1.11 | 0.97 | 1.43 | 1.14 | 1.06 | 1.12 | 0.95 | 0.86 | 0.99 | 1.23 | 1.17 | 0.94 | 1.38 | |
branched-chain, straight-chain, or cyclopropyl 10:1 fatty ac... | 1.09 | 1.05 | 0.81 | 0.33 | 0.89 | 0.86 | 1.45 | 1.20 | 1.27 | 0.74 | 1.25 | 1.39 | 1.25 | 1.30 | 0.87 | 1.31 | 0.99 | 1.14 | |
branched-chain, straight-chain, or cyclopropyl 10:1 fatty ac... | 0.91 | 1.23 | 0.95 | 0.84 | 1.01 | 0.73 | 1.03 | 1.27 | 1.08 | 1.08 | 1.02 | 0.89 | 1.05 | 1.52 | 1.00 | 1.17 | 1.12 | 0.99 | |
branched-chain, straight-chain, or cyclopropyl 10:1 fatty ac... | 1.12 | 0.71 | 0.63 | 0.45 | 0.76 | 0.58 | 0.82 | 0.63 | 0.77 | 0.46 | 1.12 | 0.78 | 1.25 | 0.60 | 0.58 | 1.10 | 1.00 | 0.88 | |
branched-chain, straight-chain, or cyclopropyl 12:1 fatty ac... | 1.47 | 0.90 | 1.09 | 0.27 | 1.27 | 0.77 | 1.37 | 0.76 | 1.30 | 0.42 | 1.29 | 0.93 | 1.64 | 0.84 | 1.01 | 1.99 | 1.19 | 0.97 | |
butyrate (4:0) | 1.28 | 1.16 | 1.10 | 0.97 | 1.07 | 1.29 | 0.97 | 0.97 | 1.14 | 0.95 | 0.99 | 1.05 | 1.07 | 1.08 | 1.05 | 0.97 | 1.03 | 1.15 | |
butyrylglycine (C4) | 0.89 | 0.74 | 0.71 | 0.57 | 0.71 | 0.81 | 1.06 | 0.80 | 0.95 | 0.85 | 0.89 | 0.98 | 0.66 | 0.99 | 0.96 | 0.96 | 0.83 | 0.91 | |
caprate (10:0) | 1.16 | 1.12 | 1.08 | 0.58 | 0.93 | 0.93 | 1.28 | 1.13 | 1.18 | 0.73 | 1.08 | 1.11 | 1.16 | 1.02 | 0.92 | 1.11 | 0.96 | 1.06 | |
caproate (6:0) | 1.14 | 1.11 | 1.00 | 0.85 | 0.92 | 1.18 | 1.14 | 1.01 | 1.04 | 1.21 | 0.97 | 1.23 | 1.01 | 1.14 | 1.02 | 1.14 | 0.98 | 1.14 | |
catechol sulfate | 1.39 | 0.99 | 1.15 | 0.71 | 0.64 | 1.29 | 1.06 | 0.89 | 0.97 | 0.61 | 0.72 | 1.35 | 1.27 | 1.14 | 1.28 | 0.73 | 1.25 | 1.42 | |
C-glycosyltryptophan | 1.14 | 0.87 | 0.85 | 0.98 | 0.82 | 1.06 | 1.14 | 0.86 | 0.92 | 1.00 | 0.89 | 1.10 | 1.10 | 1.08 | 1.06 | 1.12 | 1.08 | 1.05 | |
chenodeoxycholate | 0.55 | 1.15 | 0.50 | 0.22 | 0.68 | 0.97 | 1.29 | 1.47 | 1.04 | 0.66 | 1.03 | 1.34 | 1.55 | 1.52 | 1.31 | 0.89 | 1.05 | 1.16 | |
cholate | 0.75 | 3.32 | 1.84 | 0.80 | 0.81 | 1.23 | 1.28 | 3.68 | 1.80 | 0.92 | 1.19 | 1.27 | 2.02 | 2.24 | 1.60 | 0.97 | 1.45 | 0.91 | |
cinnamoylglycine | 1.40 | 0.53 | 0.59 | 0.35 | 0.59 | 1.25 | 1.21 | 1.30 | 1.47 | 0.47 | 1.67 | 1.70 | 1.95 | 2.84 | 1.00 | 1.91 | 2.17 | 2.41 | |
cis-4-decenoate (10:1n6)* | 1.23 | 1.09 | 0.93 | 0.27 | 1.06 | 0.93 | 1.62 | 0.98 | 1.15 | 0.59 | 1.27 | 1.04 | 1.23 | 1.02 | 0.85 | 1.35 | 1.00 | 0.85 | |
citrate | 1.06 | 1.01 | 1.07 | 0.85 | 1.06 | 1.01 | 0.99 | 0.92 | 1.06 | 0.84 | 1.04 | 0.99 | 1.07 | 1.03 | 1.08 | 1.16 | 1.04 | 1.06 | |
cortisol | 0.89 | 1.08 | 1.16 | 1.40 | 1.24 | 0.93 | 0.96 | 0.96 | 1.07 | 0.81 | 1.20 | 1.05 | 1.06 | 0.92 | 1.00 | 0.53 | 1.09 | 0.99 | |
cortisone | 1.07 | 1.03 | 1.00 | 1.02 | 1.03 | 1.05 | 1.06 | 1.02 | 1.08 | 0.96 | 1.00 | 1.06 | 1.04 | 0.95 | 0.98 | 0.69 | 1.04 | 0.97 | |
cortolone glucuronide (1) | 1.04 | 1.04 | 0.88 | 0.87 | 0.82 | 0.95 | 1.19 | 0.99 | 1.01 | 1.05 | 0.94 | 1.16 | 1.17 | 1.15 | 1.07 | 0.92 | 1.09 | 1.09 | |
daidzein sulfate (2) | 0.24 | 0.28 | 0.27 | 0.14 | 0.19 | 0.21 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | |
dehydroepiandrosterone sulfate (DHEA-S) | 0.98 | 1.06 | 0.90 | 1.12 | 0.91 | 0.98 | 1.25 | 1.01 | 0.95 | 1.42 | 0.93 | 1.23 | 1.05 | 1.01 | 0.96 | 1.08 | 1.01 | 0.97 | |
delta-CEHC | 1.00 | 1.48 | 0.86 | 0.55 | 0.71 | 0.77 | 0.91 | 1.29 | 1.13 | 0.51 | 0.87 | 0.82 | 0.77 | 1.52 | 0.84 | 0.57 | 0.77 | 0.83 | |
deoxycholate | 1.36 | 0.72 | 0.93 | 0.51 | 0.46 | 1.46 | 1.21 | 1.23 | 1.14 | 0.56 | 1.15 | 1.39 | 2.33 | 2.30 | 2.58 | 1.27 | 1.99 | 2.08 | |
deoxycholic acid (12 or 24)-sulfate* | 1.15 | 0.46 | 0.98 | 1.20 | 0.31 | 0.89 | 1.54 | 1.45 | 1.50 | 1.42 | 1.51 | 1.55 | 1.08 | 0.88 | 1.24 | 0.87 | 1.05 | 1.20 | |
deoxycholic acid glucuronide | 0.90 | 0.90 | 0.70 | 0.86 | 0.50 | 1.07 | 1.90 | 1.85 | 1.49 | 1.87 | 1.45 | 2.25 | 1.32 | 1.18 | 1.43 | 1.18 | 1.43 | 1.37 | |
desmethylnaproxen | 0.69 | 0.69 | 0.69 | 0.69 | 0.69 | 0.69 | 0.69 | 0.69 | 0.69 | 0.69 | 0.69 | 0.72 | 0.86 | 0.69 | 0.72 | 0.73 | 0.72 | 0.69 | |
desmethylnaproxen sulfate | 0.54 | 0.41 | 0.39 | 0.44 | 0.39 | 0.63 | 0.62 | 0.44 | 0.43 | 0.50 | 0.44 | 0.96 | 0.56 | 0.39 | 0.45 | 0.45 | 0.45 | 0.42 | |
dihomolinoleate (20:2n6) | 1.45 | 1.44 | 1.47 | 0.41 | 1.35 | 0.82 | 2.06 | 1.01 | 1.52 | 0.60 | 1.25 | 0.89 | 1.39 | 0.89 | 0.86 | 2.12 | 0.97 | 1.37 | |
dihomolinolenate (20:3n3 or 3n6) | 1.69 | 1.26 | 1.19 | 1.12 | 1.18 | 0.89 | 1.88 | 1.08 | 1.47 | 0.96 | 1.09 | 0.89 | 1.33 | 1.03 | 0.94 | 1.71 | 0.94 | 1.28 | |
docosadienoate (22:2n6) | 1.38 | 1.32 | 1.30 | 0.58 | 1.25 | 0.90 | 1.78 | 0.98 | 1.38 | 0.77 | 1.11 | 0.92 | 1.36 | 0.98 | 0.93 | 1.91 | 1.04 | 1.47 | |
docosahexaenoate (DHA; 22:6n3) | 1.76 | 1.36 | 1.33 | 0.92 | 1.29 | 0.78 | 1.59 | 1.07 | 1.31 | 0.74 | 0.91 | 0.75 | 1.44 | 1.24 | 1.15 | 1.79 | 1.07 | 1.39 | |
docosapentaenoate (DPA; 22:5n3) | 1.72 | 1.30 | 1.38 | 0.73 | 1.21 | 0.76 | 2.46 | 1.05 | 1.68 | 0.72 | 1.22 | 0.90 | 1.68 | 1.09 | 1.02 | 2.43 | 1.05 | 1.53 | |
docosapentaenoate (n6 DPA; 22:5n6) | 1.70 | 1.28 | 1.30 | 0.94 | 1.32 | 0.91 | 1.53 | 1.02 | 1.37 | 0.77 | 1.02 | 0.82 | 1.26 | 1.18 | 0.99 | 1.64 | 1.02 | 1.20 | |
docosatrienoate (22:3n3) | 1.54 | 1.52 | 1.41 | 0.65 | 1.40 | 0.70 | 1.94 | 1.11 | 1.45 | 0.85 | 1.21 | 1.00 | 1.42 | 0.72 | 0.76 | 1.79 | 0.86 | 1.34 | |
dodecadienoate (12:2)* | 1.23 | 1.04 | 0.98 | 0.34 | 1.07 | 0.78 | 1.12 | 0.96 | 1.06 | 0.53 | 1.12 | 0.85 | 1.31 | 1.12 | 1.04 | 1.59 | 1.18 | 0.90 | |
dodecanedioate (C12) | 1.12 | 1.46 | 1.12 | 0.59 | 1.06 | 0.91 | 1.36 | 1.29 | 1.42 | 0.69 | 1.35 | 1.17 | 1.07 | 1.04 | 0.84 | 1.43 | 0.82 | 1.00 | |
dodecenedioate (C12:1-DC)* | 0.93 | 1.64 | 1.02 | 0.39 | 1.01 | 0.69 | 1.04 | 1.12 | 1.37 | 0.47 | 1.32 | 0.87 | 0.98 | 0.88 | 0.61 | 1.79 | 0.78 | 0.57 | |
dopamine 3-O-sulfate | 1.21 | 1.00 | 0.77 | 0.91 | 0.69 | 1.28 | 1.13 | 0.84 | 0.83 | 0.82 | 0.78 | 1.24 | 1.34 | 1.73 | 1.39 | 1.08 | 1.42 | 1.86 | |
DSGEGDFXAEGGGVR* | 0.27 | 0.25 | 0.36 | 0.24 | 0.31 | 1.13 | 0.45 | 0.24 | 0.27 | 0.24 | 1.45 | 1.67 | 0.52 | 0.34 | 0.38 | 4.38 | 0.24 | 1.21 | |
EDTA | 1.06 | 1.09 | 1.05 | 1.05 | 0.99 | 1.14 | 1.06 | 0.98 | 0.94 | 1.07 | 1.17 | 1.04 | 1.03 | 1.32 | 1.05 | 1.27 | 1.02 | 0.99 | |
eicosanedioate (C20-DC) | 1.12 | 0.98 | 1.10 | 0.90 | 0.85 | 0.87 | 1.11 | 0.98 | 1.11 | 0.98 | 0.93 | 0.93 | 1.17 | 1.13 | 1.20 | 1.14 | 1.07 | 1.07 | |
eicosapentaenoate (EPA; 20:5n3) | 1.64 | 1.13 | 1.16 | 0.93 | 1.02 | 0.79 | 2.20 | 1.06 | 1.41 | 0.84 | 1.06 | 0.90 | 1.76 | 1.21 | 1.19 | 2.19 | 1.11 | 1.54 | |
eicosenedioate (C20:1-DC)* | 0.84 | 0.96 | 0.89 | 0.81 | 0.74 | 0.92 | 1.34 | 1.30 | 1.22 | 1.30 | 1.27 | 1.31 | 0.98 | 0.98 | 1.00 | 0.98 | 1.02 | 0.99 | |
eicosenoate (20:1n9 or 1n11) | 1.40 | 1.48 | 1.54 | 0.30 | 1.35 | 0.86 | 1.94 | 0.94 | 1.45 | 0.53 | 1.18 | 0.86 | 1.38 | 0.79 | 0.78 | 2.06 | 0.91 | 1.30 | |
epiandrosterone sulfate | 1.17 | 0.98 | 0.83 | 1.20 | 0.82 | 1.15 | 1.58 | 1.04 | 0.92 | 1.63 | 0.80 | 1.61 | 1.45 | 1.45 | 1.41 | 1.46 | 1.38 | 1.33 | |
erucate (22:1n9) | 1.41 | 1.33 | 1.31 | 0.73 | 1.21 | 0.91 | 1.42 | 0.95 | 1.26 | 0.79 | 0.96 | 0.89 | 1.24 | 0.97 | 0.95 | 1.66 | 1.03 | 1.44 | |
etiocholanolone glucuronide | 1.17 | 0.89 | 0.71 | 0.96 | 0.79 | 1.21 | 1.43 | 0.88 | 1.00 | 0.99 | 1.14 | 1.46 | 1.32 | 1.23 | 1.20 | 0.99 | 1.26 | 1.30 | |
Fibrinopeptide B (1-13) | 0.40 | 0.40 | 0.41 | 0.40 | 0.40 | 1.00 | 0.47 | 0.40 | 0.40 | 0.40 | 0.67 | 0.61 | 0.42 | 0.41 | 0.40 | 3.27 | 0.40 | 0.67 | |
gamma-CEHC | 0.99 | 1.92 | 1.28 | 0.82 | 0.81 | 0.79 | 1.00 | 1.81 | 1.37 | 0.90 | 1.10 | 0.85 | 1.02 | 1.57 | 1.36 | 0.78 | 1.17 | 0.83 | |
gamma-glutamylleucine | 1.42 | 0.76 | 0.60 | 0.61 | 0.53 | 1.31 | 1.30 | 0.74 | 0.84 | 0.72 | 0.82 | 1.27 | 1.49 | 1.55 | 1.49 | 1.37 | 1.38 | 1.50 | |
gamma-glutamylphenylalanine | 1.38 | 0.70 | 0.67 | 0.68 | 0.62 | 1.24 | 1.41 | 0.79 | 0.84 | 0.79 | 0.85 | 1.40 | 1.42 | 1.55 | 1.38 | 1.32 | 1.28 | 1.45 | |
genistein sulfate* | 0.91 | 1.76 | 1.23 | 0.29 | 1.33 | 0.55 | 0.22 | 0.33 | 0.22 | 0.22 | 0.22 | 0.22 | 0.23 | 0.34 | 0.33 | 0.22 | 0.39 | 0.22 | |
glucuronide of piperine metabolite C17H21NO3 (4)* | 0.65 | 1.16 | 0.90 | 0.95 | 0.95 | 1.15 | 1.08 | 1.19 | 0.74 | 0.99 | 0.90 | 1.62 | 2.07 | 2.19 | 1.74 | 1.66 | 1.86 | 3.12 | |
glutamine conjugate of C6H10O2 (2)* | 0.73 | 2.35 | 1.59 | 0.24 | 1.74 | 0.70 | 0.88 | 1.28 | 1.53 | 0.43 | 2.14 | 0.78 | 1.12 | 0.76 | 0.71 | 2.35 | 0.96 | 0.93 | |
glycerol | 1.41 | 0.87 | 1.08 | 0.62 | 0.99 | 1.15 | 2.07 | 0.91 | 1.21 | 0.79 | 1.27 | 1.24 | 1.55 | 0.96 | 0.95 | 1.54 | 0.98 | 1.20 | |
glycine conjugate of C10H14O2 (1)* | 0.92 | 1.01 | 0.82 | 0.69 | 0.86 | 0.74 | 1.15 | 1.38 | 1.16 | 0.87 | 1.19 | 0.93 | 1.13 | 2.27 | 1.01 | 1.01 | 1.23 | 1.05 | |
glyco-beta-muricholate | 0.83 | 1.04 | 0.84 | 0.33 | 0.47 | 0.85 | 0.87 | 1.54 | 0.87 | 0.34 | 1.15 | 0.82 | 0.84 | 1.75 | 1.24 | 0.87 | 1.61 | 0.96 | |
glycochenodeoxycholate | 1.42 | 1.51 | 1.29 | 0.61 | 1.12 | 1.62 | 1.62 | 1.61 | 1.12 | 0.49 | 1.44 | 1.52 | 1.38 | 2.35 | 1.57 | 1.42 | 1.18 | 1.56 | |
glycochenodeoxycholate 3-sulfate | 1.51 | 2.14 | 1.34 | 0.86 | 1.16 | 1.53 | 1.23 | 1.72 | 0.75 | 0.77 | 1.17 | 1.02 | 0.89 | 1.42 | 0.79 | 1.08 | 1.20 | 1.10 | |
glycochenodeoxycholate glucuronide (1) | 0.91 | 1.25 | 0.57 | 0.69 | 0.34 | 0.85 | 2.56 | 2.70 | 1.78 | 2.37 | 1.82 | 2.80 | 1.05 | 1.92 | 1.33 | 0.87 | 1.24 | 1.19 | |
glycocholate | 1.73 | 2.41 | 2.26 | 1.06 | 1.17 | 2.10 | 1.40 | 1.93 | 1.03 | 0.45 | 1.51 | 1.55 | 1.22 | 2.25 | 1.20 | 1.26 | 1.02 | 1.52 | |
glycocholenate sulfate* | 1.00 | 0.94 | 0.64 | 1.71 | 0.50 | 0.93 | 1.53 | 1.43 | 1.19 | 2.03 | 1.11 | 1.43 | 0.99 | 0.90 | 0.95 | 1.06 | 1.03 | 0.92 | |
glycodeoxycholate | 1.63 | 1.47 | 1.12 | 0.56 | 0.99 | 1.57 | 1.50 | 1.52 | 1.26 | 0.36 | 1.55 | 1.33 | 1.79 | 3.94 | 2.55 | 1.95 | 1.99 | 2.14 | |
glycodeoxycholate 3-sulfate | 1.07 | 1.42 | 0.86 | 0.89 | 0.81 | 1.03 | 1.48 | 1.90 | 1.16 | 1.02 | 1.70 | 1.28 | 1.49 | 1.99 | 1.97 | 1.75 | 1.98 | 1.40 | |
glycohyocholate | 1.37 | 1.69 | 1.84 | 0.52 | 1.14 | 1.75 | 0.85 | 1.18 | 0.74 | 0.44 | 1.12 | 0.69 | 0.82 | 1.12 | 0.79 | 1.05 | 1.11 | 0.91 | |
glycolithocholate | 1.50 | 0.33 | 0.53 | 0.90 | 0.42 | 0.81 | 1.01 | 0.59 | 1.13 | 0.50 | 0.58 | 0.74 | 0.75 | 0.73 | 0.77 | 1.11 | 0.53 | 1.23 | |
glycolithocholate sulfate* | 1.40 | 1.37 | 0.73 | 1.46 | 0.46 | 1.16 | 1.24 | 1.55 | 0.95 | 1.12 | 0.95 | 1.12 | 1.11 | 1.50 | 1.16 | 1.34 | 0.89 | 1.17 | |
glycoursodeoxycholate | 1.89 | 1.99 | 2.19 | 0.68 | 2.08 | 2.13 | 2.95 | 2.40 | 1.93 | 0.84 | 3.02 | 2.06 | 1.39 | 2.40 | 1.97 | 1.59 | 1.55 | 1.57 | |
guaiacol sulfate | 1.39 | 1.29 | 1.13 | 0.75 | 0.73 | 1.38 | 1.20 | 0.81 | 0.92 | 0.60 | 0.67 | 1.36 | 1.42 | 1.23 | 1.43 | 0.87 | 1.27 | 1.39 | |
heptanoate (7:0) | 1.41 | 1.26 | 1.35 | 1.43 | 1.40 | 1.07 | 1.00 | 0.88 | 1.05 | 1.30 | 1.08 | 1.50 | 1.21 | 1.24 | 1.75 | 1.60 | 1.47 | 1.08 | |
hexadecadienoate (16:2n6) | 1.41 | 0.84 | 1.13 | 0.25 | 1.05 | 0.83 | 2.00 | 0.83 | 1.50 | 0.50 | 1.28 | 1.20 | 1.43 | 0.89 | 0.81 | 1.72 | 1.19 | 1.04 | |
hexadecanedioate (C16) | 1.04 | 1.33 | 1.13 | 0.60 | 0.95 | 0.89 | 1.43 | 1.43 | 1.62 | 0.99 | 1.49 | 1.40 | 1.09 | 0.99 | 0.89 | 1.58 | 0.98 | 0.97 | |
hexadecenedioate (C16:1-DC)* | 0.95 | 1.26 | 1.08 | 0.58 | 0.91 | 0.73 | 1.42 | 1.54 | 1.76 | 1.04 | 1.54 | 1.20 | 1.02 | 0.93 | 0.86 | 1.42 | 0.91 | 0.88 | |
hippurate | 1.55 | 0.84 | 1.22 | 0.55 | 0.84 | 1.18 | 1.16 | 0.93 | 1.02 | 0.52 | 1.10 | 1.21 | 1.38 | 1.19 | 1.35 | 0.80 | 1.15 | 1.29 | |
histidine | 1.17 | 0.82 | 0.80 | 0.73 | 0.77 | 1.16 | 1.18 | 0.81 | 0.98 | 0.79 | 0.93 | 1.16 | 1.03 | 1.02 | 1.04 | 0.98 | 1.01 | 1.05 | |
hydrochlorothiazide | 0.86 | 0.86 | 0.86 | 0.86 | 0.86 | 0.86 | 0.86 | 0.86 | 0.86 | 0.86 | 0.86 | 0.86 | 0.89 | 0.87 | 0.87 | 0.86 | 0.88 | 0.92 | |
hydroquinone sulfate | 0.62 | 0.98 | 0.40 | 0.48 | 0.59 | 1.09 | 0.56 | 0.90 | 0.43 | 0.44 | 0.57 | 1.30 | 0.88 | 2.33 | 0.77 | 0.99 | 0.99 | 1.56 | |
hyocholate | 0.72 | 1.36 | 0.81 | 0.66 | 0.68 | 0.91 | 0.94 | 1.25 | 0.82 | 1.02 | 0.99 | 0.88 | 1.08 | 1.02 | 1.06 | 0.92 | 1.05 | 0.83 | |
hypoxanthine | 1.28 | 1.02 | 1.07 | 1.00 | 0.91 | 1.16 | 1.32 | 0.87 | 0.88 | 1.13 | 1.05 | 1.20 | 1.20 | 0.69 | 0.82 | 0.99 | 0.84 | 0.97 | |
indoleacetate | 1.64 | 1.47 | 1.02 | 0.92 | 1.17 | 1.39 | 1.29 | 1.32 | 1.19 | 0.79 | 1.25 | 1.37 | 1.04 | 1.66 | 1.03 | 0.72 | 1.37 | 1.28 | |
indolelactate | 0.88 | 1.45 | 1.34 | 0.81 | 1.23 | 0.85 | 1.02 | 1.54 | 1.36 | 1.00 | 1.28 | 1.10 | 0.86 | 0.93 | 0.87 | 0.69 | 0.85 | 0.88 | |
indolepropionate | 1.08 | 1.80 | 0.93 | 0.86 | 0.61 | 1.80 | 0.88 | 2.14 | 0.77 | 0.88 | 0.78 | 2.20 | 0.91 | 2.16 | 0.87 | 0.76 | 1.21 | 1.50 | |
isobutyrylglycine (C4) | 0.90 | 0.76 | 0.92 | 0.74 | 0.87 | 0.87 | 1.07 | 0.84 | 1.00 | 1.01 | 1.04 | 1.03 | 0.86 | 1.22 | 1.04 | 0.90 | 0.88 | 1.00 | |
isoursodeoxycholate | 2.61 | 1.94 | 2.48 | 1.50 | 1.44 | 2.63 | 1.97 | 2.00 | 1.88 | 1.91 | 1.51 | 1.71 | 1.37 | 1.67 | 1.99 | 1.45 | 1.76 | 1.55 | |
isovalerate (C5) | 1.32 | 1.91 | 1.46 | 0.76 | 1.23 | 1.15 | 0.89 | 1.28 | 1.23 | 0.89 | 1.29 | 1.04 | 0.87 | 0.83 | 1.01 | 1.06 | 0.78 | 0.95 | |
isovalerylglycine | 0.69 | 0.77 | 0.83 | 0.86 | 0.73 | 0.79 | 0.68 | 0.57 | 0.72 | 0.68 | 0.87 | 0.82 | 0.79 | 0.96 | 0.84 | 0.63 | 0.81 | 0.94 | |
kynurenate | 0.91 | 1.20 | 1.20 | 0.41 | 1.16 | 0.81 | 0.92 | 1.00 | 1.25 | 0.48 | 1.20 | 0.86 | 1.09 | 0.96 | 1.06 | 0.80 | 0.99 | 1.03 | |
laurate (12:0) | 1.45 | 1.00 | 1.26 | 0.40 | 1.13 | 0.97 | 1.61 | 0.93 | 1.21 | 0.62 | 1.05 | 1.10 | 1.32 | 0.74 | 0.82 | 1.36 | 0.86 | 1.08 | |
linoleate (18:2n6) | 1.24 | 1.20 | 1.11 | 0.23 | 1.13 | 0.75 | 1.59 | 0.92 | 1.28 | 0.44 | 1.05 | 0.84 | 1.37 | 0.93 | 0.80 | 1.69 | 0.93 | 1.22 | |
linolenate (18:3n3 or 3n6) | 1.36 | 1.33 | 1.15 | 0.18 | 1.07 | 0.72 | 2.02 | 1.05 | 1.31 | 0.39 | 1.11 | 0.89 | 1.50 | 1.03 | 0.81 | 1.82 | 0.90 | 1.30 | |
linoleoyl ethanolamide | 1.26 | 1.35 | 1.14 | 0.56 | 1.02 | 0.87 | 1.70 | 1.06 | 1.29 | 0.71 | 1.00 | 0.82 | 1.05 | 0.94 | 0.67 | 1.37 | 0.82 | 1.21 | |
lithocholate sulfate (1) | 1.64 | 0.74 | 0.96 | 2.05 | 0.39 | 1.17 | 0.99 | 1.18 | 0.94 | 1.49 | 0.83 | 1.11 | 1.00 | 0.83 | 0.80 | 1.07 | 0.80 | 0.81 | |
malate | 1.12 | 0.97 | 1.03 | 1.01 | 1.06 | 1.02 | 1.04 | 0.82 | 0.99 | 0.87 | 0.92 | 0.97 | 1.19 | 1.04 | 1.09 | 1.13 | 1.10 | 1.09 | |
margarate (17:0) | 1.48 | 1.52 | 1.48 | 0.46 | 1.39 | 0.87 | 1.82 | 1.04 | 1.48 | 0.58 | 1.16 | 0.89 | 1.49 | 0.95 | 0.98 | 1.89 | 1.04 | 1.44 | |
metabolonic lactone sulfate | 1.24 | 0.97 | 0.86 | 1.12 | 0.82 | 1.09 | 1.38 | 1.18 | 1.14 | 1.46 | 1.09 | 1.36 | 1.13 | 1.19 | 1.12 | 1.12 | 1.07 | 1.12 | |
methyl-4-hydroxybenzoate sulfate | 2.80 | 6.30 | 6.97 | 4.09 | 3.16 | 7.94 | 2.64 | 1.82 | 2.01 | 0.91 | 0.92 | 0.57 | 1.34 | 1.37 | 1.36 | 0.93 | 1.23 | 2.61 | |
methyl glucopyranoside (alpha + beta) | 1.16 | 0.44 | 0.28 | 0.83 | 0.35 | 1.48 | 1.66 | 0.68 | 0.57 | 1.19 | 0.65 | 2.01 | 1.51 | 1.09 | 1.14 | 1.26 | 1.40 | 1.55 | |
myristate (14:0) | 1.49 | 1.10 | 1.22 | 0.33 | 1.06 | 0.89 | 2.15 | 0.88 | 1.36 | 0.48 | 1.04 | 0.95 | 1.50 | 0.79 | 0.86 | 1.78 | 0.87 | 1.39 | |
myristoleate (14:1n5) | 1.49 | 0.78 | 1.10 | 0.20 | 1.03 | 0.94 | 2.26 | 0.84 | 1.55 | 0.51 | 1.36 | 1.32 | 1.61 | 0.71 | 0.88 | 1.75 | 0.97 | 1.16 | |
N1-Methyl-2-pyridone-5-carboxamide | 1.17 | 1.30 | 0.64 | 1.02 | 0.61 | 1.04 | 1.12 | 1.11 | 0.72 | 0.97 | 0.69 | 1.11 | 1.07 | 1.25 | 1.14 | 1.06 | 1.13 | 1.03 | |
N6-carbamoylthreonyladenosine | 0.89 | 0.85 | 0.91 | 0.98 | 0.93 | 0.83 | 0.94 | 0.83 | 0.89 | 1.00 | 0.91 | 1.04 | 0.94 | 0.86 | 0.86 | 0.86 | 0.94 | 0.90 | |
N-acetyl-2-aminooctanoate* | 1.40 | 0.95 | 0.54 | 1.39 | 0.64 | 1.65 | 1.04 | 0.61 | 0.48 | 0.82 | 0.67 | 0.99 | 1.55 | 1.94 | 1.69 | 1.25 | 1.59 | 2.17 | |
N-acetylaspartate (NAA) | 1.11 | 0.98 | 0.95 | 0.94 | 0.93 | 1.02 | 0.99 | 0.92 | 0.98 | 0.89 | 1.00 | 0.93 | 1.06 | 0.95 | 1.09 | 1.00 | 1.09 | 1.00 | |
N-acetylleucine | 1.19 | 0.98 | 0.82 | 0.82 | 0.59 | 1.19 | 0.95 | 0.83 | 0.82 | 0.80 | 0.93 | 0.97 | 0.97 | 0.90 | 1.12 | 0.92 | 0.94 | 1.08 | |
N-acetylmethionine | 1.10 | 0.94 | 0.86 | 0.93 | 0.86 | 1.11 | 1.07 | 0.81 | 0.87 | 0.95 | 0.91 | 1.09 | 1.04 | 1.15 | 1.03 | 1.08 | 1.03 | 1.10 | |
N-acetylphenylalanine | 1.16 | 1.05 | 1.14 | 0.88 | 0.98 | 1.18 | 1.17 | 0.95 | 1.02 | 0.90 | 1.01 | 1.11 | 1.26 | 1.37 | 1.23 | 1.24 | 1.16 | 1.23 | |
N-acetylthreonine | 1.25 | 0.85 | 0.78 | 1.03 | 0.70 | 1.17 | 1.21 | 0.75 | 0.77 | 1.01 | 0.78 | 1.18 | 1.15 | 1.20 | 1.16 | 1.10 | 1.15 | 1.20 | |
N-acetylvaline | 1.17 | 0.86 | 0.90 | 0.91 | 0.74 | 1.11 | 1.16 | 0.91 | 0.90 | 0.96 | 0.86 | 1.08 | 1.13 | 1.11 | 1.08 | 1.20 | 1.12 | 1.10 | |
naproxen | 0.30 | 0.16 | 0.10 | 0.22 | 0.07 | 0.55 | 0.78 | 0.36 | 0.19 | 0.69 | 0.12 | 1.69 | 0.24 | 0.05 | 0.14 | 0.14 | 0.15 | 0.11 | |
nervonate (24:1n9)* | 1.32 | 1.60 | 1.37 | 0.70 | 1.17 | 1.02 | 1.31 | 1.05 | 1.05 | 0.87 | 0.95 | 0.94 | 1.26 | 1.06 | 1.09 | 1.42 | 1.06 | 1.55 | |
N-formylmethionine | 1.06 | 0.87 | 0.88 | 0.91 | 0.85 | 1.06 | 1.09 | 0.86 | 0.96 | 0.99 | 0.97 | 1.12 | 1.07 | 1.19 | 1.07 | 1.06 | 1.06 | 1.11 | |
nonadecanoate (19:0) | 1.35 | 1.50 | 1.51 | 0.75 | 1.34 | 0.94 | 1.47 | 1.08 | 1.31 | 0.78 | 1.06 | 0.90 | 1.22 | 1.08 | 0.99 | 1.52 | 1.04 | 1.40 | |
N-palmitoylglycine | 1.46 | 0.96 | 0.89 | 0.60 | 1.05 | 1.06 | 1.53 | 0.82 | 1.22 | 0.72 | 0.98 | 0.96 | 1.15 | 1.08 | 1.07 | 1.45 | 1.16 | 1.37 | |
N-palmitoylserine | 0.76 | 0.48 | 0.53 | 1.32 | 0.47 | 0.74 | 0.72 | 0.70 | 0.67 | 0.98 | 0.49 | 0.55 | 0.48 | 0.85 | 1.13 | 0.40 | 0.76 | 1.04 | |
octadecadienedioate (C18:2-DC)* | 0.85 | 3.52 | 0.98 | 0.51 | 1.18 | 0.76 | 1.19 | 4.37 | 1.40 | 0.98 | 2.02 | 1.30 | 1.11 | 5.08 | 0.98 | 1.08 | 2.28 | 0.89 | |
octadecanedioate (C18) | 1.11 | 1.05 | 1.10 | 0.56 | 0.95 | 0.81 | 1.14 | 1.05 | 1.33 | 0.83 | 1.26 | 0.99 | 1.15 | 1.09 | 1.01 | 1.37 | 0.97 | 0.96 | |
octadecenedioate (C18:1-DC)* | 0.97 | 1.52 | 1.01 | 0.55 | 0.93 | 0.87 | 1.22 | 1.64 | 1.31 | 0.92 | 1.40 | 1.29 | 1.09 | 1.63 | 1.04 | 1.29 | 1.17 | 1.11 | |
oleate/vaccenate (18:1) | 1.27 | 1.13 | 1.16 | 0.25 | 1.17 | 0.83 | 1.51 | 0.88 | 1.27 | 0.49 | 1.05 | 0.87 | 1.26 | 0.78 | 0.81 | 1.55 | 0.90 | 1.15 | |
oleoyl ethanolamide | 1.50 | 1.20 | 1.27 | 0.65 | 1.17 | 1.13 | 1.73 | 1.00 | 1.23 | 0.85 | 1.12 | 0.96 | 1.21 | 0.90 | 0.85 | 1.42 | 0.87 | 1.26 | |
O-sulfo-L-tyrosine | 1.25 | 0.66 | 0.67 | 0.90 | 0.66 | 1.23 | 1.34 | 0.71 | 0.83 | 1.02 | 0.80 | 1.29 | 1.29 | 1.36 | 1.21 | 1.26 | 1.28 | 1.33 | |
oxalate (ethanedioate) | 1.10 | 1.01 | 0.97 | 0.90 | 0.96 | 1.04 | 0.91 | 0.83 | 0.89 | 0.67 | 0.88 | 0.82 | 1.04 | 0.93 | 1.12 | 0.94 | 1.18 | 0.99 | |
palmitate (16:0) | 1.25 | 1.14 | 1.15 | 0.44 | 1.16 | 0.87 | 1.44 | 0.90 | 1.25 | 0.58 | 1.04 | 0.87 | 1.26 | 0.88 | 0.87 | 1.48 | 0.92 | 1.20 | |
palmitoleate (16:1n7) | 1.84 | 0.99 | 1.31 | 0.22 | 1.20 | 0.95 | 3.07 | 0.87 | 1.84 | 0.55 | 1.36 | 1.21 | 1.80 | 0.79 | 0.87 | 2.43 | 1.04 | 1.62 | |
palmitoyl ethanolamide | 1.29 | 1.18 | 1.19 | 0.82 | 0.99 | 1.11 | 1.53 | 1.02 | 1.22 | 0.89 | 0.97 | 1.02 | 1.12 | 0.99 | 0.97 | 1.31 | 0.95 | 1.33 | |
pantothenate (Vitamin B5) | 1.04 | 0.86 | 0.98 | 0.68 | 1.05 | 1.04 | 1.11 | 0.81 | 1.04 | 0.80 | 1.07 | 1.15 | 1.63 | 1.59 | 1.64 | 1.72 | 1.69 | 1.66 | |
p-cresol sulfate | 1.42 | 1.11 | 0.84 | 1.35 | 0.60 | 1.16 | 0.93 | 0.94 | 0.79 | 0.96 | 0.68 | 0.86 | 1.27 | 1.55 | 1.15 | 1.19 | 1.01 | 1.27 | |
pentadecanoate (15:0) | 1.37 | 1.23 | 1.24 | 0.68 | 1.16 | 0.96 | 1.64 | 0.96 | 1.28 | 0.72 | 0.98 | 0.90 | 1.31 | 0.99 | 1.01 | 1.57 | 0.96 | 1.38 | |
perfluorooctanesulfonate (PFOS) | 0.95 | 1.32 | 1.12 | 1.24 | 1.24 | 1.04 | 1.46 | 1.41 | 1.38 | 1.42 | 0.89 | 1.15 | 0.94 | 0.95 | 1.15 | 1.00 | 0.95 | 1.25 | |
phenol sulfate | 1.38 | 1.54 | 0.79 | 1.35 | 0.75 | 1.15 | 1.30 | 1.54 | 0.79 | 1.40 | 0.86 | 1.10 | 2.06 | 3.29 | 2.08 | 2.11 | 1.52 | 1.42 | |
phenylacetate | 1.59 | 1.23 | 0.83 | 1.23 | 0.75 | 1.05 | 3.87 | 4.27 | 4.09 | 5.20 | 3.82 | 4.37 | 0.90 | 1.32 | 0.82 | 0.96 | 0.73 | 0.75 | |
phenylacetylglutamine | 1.45 | 1.21 | 0.88 | 1.17 | 0.77 | 1.03 | 1.04 | 1.03 | 0.84 | 0.89 | 0.84 | 0.95 | 1.30 | 1.75 | 1.14 | 1.28 | 0.91 | 1.26 | |
phenylalanyltryptophan | 1.27 | 0.87 | 0.65 | 0.87 | 0.61 | 1.12 | 1.21 | 0.88 | 0.87 | 0.92 | 0.74 | 1.18 | 1.36 | 1.23 | 1.29 | 1.52 | 1.26 | 1.21 | |
phenyllactate (PLA) | 0.98 | 1.09 | 1.13 | 0.75 | 1.08 | 0.97 | 1.17 | 1.22 | 1.34 | 1.04 | 1.28 | 1.23 | 1.09 | 1.15 | 1.14 | 0.99 | 1.09 | 1.07 | |
phytanate | 1.65 | 1.33 | 1.74 | 0.73 | 1.22 | 1.25 | 1.49 | 0.98 | 1.36 | 0.68 | 0.90 | 0.97 | 1.25 | 1.16 | 1.30 | 1.38 | 1.06 | 1.85 | |
pregnanediol-3-glucuronide | 1.85 | 1.05 | 1.19 | 2.36 | 0.96 | 1.81 | 2.61 | 2.55 | 2.58 | 2.86 | 2.30 | 2.57 | 1.63 | 1.82 | 1.35 | 1.75 | 2.23 | 1.34 | |
pregnen-diol disulfate* | 1.24 | 1.42 | 1.38 | 1.26 | 1.44 | 1.18 | 1.35 | 1.30 | 1.22 | 1.53 | 1.28 | 1.38 | 0.99 | 1.05 | 0.95 | 1.04 | 1.03 | 0.90 | |
pregnenediol sulfate (C21H34O5S)* | 1.10 | 1.46 | 1.01 | 1.40 | 1.04 | 0.98 | 1.29 | 1.24 | 1.07 | 1.30 | 1.05 | 1.18 | 1.20 | 1.04 | 1.10 | 1.00 | 1.19 | 1.05 | |
pregnenetriol disulfate* | 1.03 | 1.35 | 1.11 | 1.21 | 1.10 | 1.02 | 1.16 | 1.14 | 0.96 | 1.39 | 0.97 | 1.21 | 0.95 | 1.01 | 0.83 | 0.93 | 0.94 | 0.85 | |
pregnenetriol sulfate* | 1.01 | 1.23 | 0.86 | 1.35 | 0.88 | 0.94 | 1.19 | 0.96 | 0.88 | 1.19 | 0.89 | 1.15 | 1.14 | 1.01 | 1.01 | 0.98 | 1.13 | 0.98 | |
pregnenolone sulfate | 1.11 | 1.19 | 0.82 | 2.96 | 0.85 | 0.94 | 1.35 | 1.08 | 0.93 | 1.75 | 0.92 | 1.21 | 1.21 | 0.90 | 1.14 | 0.89 | 1.21 | 1.22 | |
propyl 4-hydroxybenzoate sulfate | 0.43 | 0.86 | 1.09 | 0.62 | 0.34 | 1.43 | 0.58 | 0.35 | 0.53 | 0.34 | 0.23 | 0.13 | 0.27 | 0.29 | 0.30 | 0.22 | 0.33 | 0.40 | |
pseudouridine | 1.07 | 0.87 | 0.83 | 0.95 | 0.80 | 1.03 | 1.08 | 0.86 | 0.86 | 1.00 | 0.89 | 1.10 | 1.08 | 1.13 | 1.09 | 1.09 | 1.09 | 1.09 | |
pyridoxate | 1.10 | 1.17 | 0.91 | 0.93 | 0.89 | 0.91 | 0.97 | 1.06 | 1.07 | 0.83 | 1.08 | 0.87 | 1.25 | 1.61 | 1.44 | 1.06 | 1.39 | 1.10 | |
stearate (18:0) | 1.25 | 1.32 | 1.25 | 0.66 | 1.27 | 0.91 | 1.37 | 1.03 | 1.28 | 0.72 | 1.08 | 0.91 | 1.18 | 1.00 | 0.94 | 1.40 | 1.01 | 1.22 | |
stearidonate (18:4n3) | 1.25 | 0.57 | 0.76 | 0.19 | 0.73 | 0.88 | 2.18 | 0.81 | 1.25 | 0.46 | 1.22 | 1.17 | 1.73 | 0.91 | 1.01 | 1.66 | 1.18 | 1.06 | |
sulfate* | 1.03 | 0.96 | 0.93 | 1.25 | 0.89 | 1.00 | 1.09 | 0.94 | 1.00 | 1.11 | 0.93 | 1.08 | 1.04 | 1.03 | 1.04 | 0.98 | 1.01 | 1.03 | |
sulfate of piperine metabolite C16H19NO3 (2)* | 0.84 | 1.34 | 0.96 | 0.93 | 1.05 | 1.29 | 1.07 | 1.31 | 0.79 | 1.00 | 1.04 | 1.52 | 1.63 | 1.73 | 1.22 | 1.28 | 1.41 | 2.28 | |
sulfate of piperine metabolite C16H19NO3 (3)* | 0.85 | 1.11 | 0.80 | 0.86 | 0.96 | 1.17 | 1.06 | 1.21 | 0.71 | 0.87 | 0.99 | 1.54 | 1.71 | 1.84 | 1.13 | 1.37 | 1.38 | 2.14 | |
sulfate of piperine metabolite C18H21NO3 (3)* | 0.77 | 0.88 | 0.78 | 0.63 | 0.87 | 0.80 | 0.81 | 0.86 | 0.74 | 0.64 | 0.99 | 0.89 | 1.26 | 1.25 | 1.18 | 1.22 | 1.15 | 1.35 | |
tartronate (hydroxymalonate) | 1.09 | 1.11 | 1.07 | 0.95 | 1.01 | 1.01 | 0.95 | 0.83 | 1.02 | 0.66 | 0.86 | 0.75 | 1.03 | 0.94 | 1.12 | 0.90 | 1.17 | 0.96 | |
taurochenodeoxycholate | 1.72 | 1.77 | 1.61 | 1.09 | 1.65 | 2.00 | 1.12 | 1.57 | 0.77 | 0.37 | 1.06 | 1.10 | 1.39 | 2.13 | 1.55 | 1.50 | 1.14 | 1.55 | |
taurocholate | 1.63 | 2.09 | 1.91 | 1.73 | 1.13 | 2.09 | 0.91 | 1.20 | 0.59 | 0.45 | 1.00 | 1.03 | 0.80 | 1.54 | 1.02 | 1.01 | 0.89 | 1.06 | |
taurocholenate sulfate* | 1.21 | 1.76 | 1.19 | 2.11 | 1.18 | 1.00 | 1.13 | 1.15 | 0.91 | 1.72 | 0.89 | 1.01 | 1.08 | 1.02 | 0.89 | 1.35 | 1.11 | 0.94 | |
taurodeoxycholate | 1.73 | 1.80 | 1.31 | 0.79 | 1.39 | 1.45 | 0.93 | 1.49 | 0.74 | 0.26 | 1.14 | 0.97 | 1.48 | 3.23 | 1.99 | 1.80 | 1.52 | 1.90 | |
taurolithocholate 3-sulfate | 1.52 | 2.45 | 1.35 | 1.38 | 1.05 | 1.04 | 1.07 | 1.77 | 0.84 | 0.81 | 0.99 | 0.67 | 1.05 | 1.93 | 1.07 | 1.62 | 1.01 | 1.05 | |
tetradecadienedioate (C14:2-DC)* | 0.84 | 0.79 | 0.85 | 0.26 | 0.90 | 0.48 | 0.92 | 0.85 | 1.44 | 0.57 | 1.55 | 0.73 | 0.87 | 0.53 | 0.60 | 1.55 | 0.83 | 0.74 | |
tetradecadienoate (14:2)* | 1.43 | 0.92 | 0.96 | 0.30 | 1.21 | 0.84 | 1.55 | 0.89 | 1.29 | 0.54 | 1.36 | 1.02 | 1.53 | 0.88 | 0.91 | 1.73 | 1.10 | 0.93 | |
tetradecanedioate (C14) | 1.00 | 1.28 | 1.07 | 0.66 | 0.89 | 0.81 | 1.41 | 1.46 | 1.54 | 0.97 | 1.44 | 1.33 | 1.03 | 0.91 | 0.90 | 1.50 | 0.93 | 0.96 | |
theophylline | 0.46 | 0.31 | 0.31 | 0.41 | 0.25 | 0.76 | 0.20 | 0.21 | 0.20 | 0.23 | 0.20 | 0.79 | 0.61 | 0.25 | 0.20 | 0.55 | 0.20 | 1.89 | |
thymol sulfate | 2.47 | 1.08 | 0.91 | 1.71 | 0.53 | 7.08 | 1.98 | 0.77 | 0.27 | 1.39 | 0.10 | 6.96 | 1.59 | 1.30 | 0.69 | 1.13 | 0.72 | 7.10 | |
thyroxine | 1.01 | 1.00 | 1.10 | 1.01 | 1.12 | 0.92 | 1.03 | 0.92 | 1.02 | 0.95 | 1.05 | 0.92 | 1.03 | 1.08 | 0.99 | 1.03 | 1.03 | 1.00 | |
trans-2-hexenoylglycine | 0.67 | 0.64 | 0.71 | 0.41 | 0.94 | 0.49 | 0.94 | 0.93 | 1.39 | 0.53 | 1.47 | 0.68 | 1.10 | 1.04 | 0.40 | 1.95 | 1.08 | 0.83 | |
tridecenedioate (C13:1-DC)* | 0.95 | 0.95 | 1.16 | 0.62 | 0.95 | 0.73 | 1.26 | 1.08 | 1.40 | 0.97 | 1.36 | 1.07 | 1.20 | 0.88 | 0.90 | 1.68 | 1.00 | 1.00 | |
undecanedioate (C11-DC) | 0.82 | 1.12 | 0.81 | 0.62 | 0.65 | 0.84 | 0.72 | 0.99 | 0.76 | 0.66 | 0.97 | 0.82 | 0.85 | 1.02 | 0.84 | 0.95 | 0.90 | 0.74 | |
urate | 1.07 | 0.98 | 0.86 | 1.02 | 0.78 | 1.03 | 1.09 | 0.92 | 0.92 | 1.08 | 0.85 | 1.10 | 1.11 | 1.16 | 1.09 | 1.09 | 1.06 | 1.08 | |
uridine | 1.08 | 0.97 | 1.13 | 0.69 | 1.18 | 1.00 | 1.00 | 0.98 | 1.12 | 0.70 | 1.08 | 1.02 | 1.01 | 0.96 | 0.95 | 0.99 | 0.97 | 0.95 | |
ursodeoxycholate | 1.15 | 0.88 | 1.01 | 0.41 | 0.78 | 1.52 | 1.61 | 1.39 | 1.38 | 0.72 | 1.39 | 1.60 | 1.53 | 1.99 | 1.96 | 0.84 | 1.69 | 1.33 | |
vanillylmandelate (VMA) | 1.03 | 0.85 | 0.80 | 0.95 | 0.83 | 0.91 | 1.16 | 0.78 | 0.90 | 1.05 | 1.07 | 0.97 | 1.16 | 1.23 | 1.01 | 1.05 | 1.03 | 1.06 |
Factors:
F1 | Group:High-Dose | TIMEPOINT:-0.5HR |
F2 | Group:High-Dose | TIMEPOINT:+23HR POST INFUSION |
F3 | Group:High-Dose | TIMEPOINT:+47HR POST INFUSION |
F4 | Group:High-Dose | TIMEPOINT:+4HR POST INFUSION |
F5 | Group:High-Dose | TIMEPOINT:+71HR POST INFUSION |
F6 | Group:High-Dose | TIMEPOINT:BASELINE |
F7 | Group:Low-Dose | TIMEPOINT:-0.5HR |
F8 | Group:Low-Dose | TIMEPOINT:+23HR POST INFUSION |
F9 | Group:Low-Dose | TIMEPOINT:+47HR POST INFUSION |
F10 | Group:Low-Dose | TIMEPOINT:+4HR POST INFUSION |
F11 | Group:Low-Dose | TIMEPOINT:+71HR POST INFUSION |
F12 | Group:Low-Dose | TIMEPOINT:BASELINE |
F13 | Group:Placebo | TIMEPOINT:-0.5HR |
F14 | Group:Placebo | TIMEPOINT:+23HR POST INFUSION |
F15 | Group:Placebo | TIMEPOINT:+47HR POST INFUSION |
F16 | Group:Placebo | TIMEPOINT:+4HR POST INFUSION |
F17 | Group:Placebo | TIMEPOINT:+71HR POST INFUSION |
F18 | Group:Placebo | TIMEPOINT:BASELINE |