Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST000566)

Reversed phase POSITIVE ION MODE (Analysis AN000870)

Metabolite	Structure	F1	F2	F3	F4	F5	F6
Lys Asn Pro	ME167939	1.07	1.28	0.81	0.72	NA	1.04
Mycalamide A	ME167904	0.82	1.41	1.81	0.81	NA	0.16
3-O-Methyl-myo-inositol	ME167893	1.20	1.15	1.01	1.39	NA	0.23
PE(21:0/20:1(11Z))	ME167945	0.92	1.00	0.87	0.89	NA	1.32
b-Glucose	ME167849	1.02	1.02	1.00	1.01	NA	0.94
8E-Heptadecenedioic acid	ME167903	1.16	1.16	1.00	0.99	NA	0.64
cis-Caryophyllene	ME167909	0.69	0.71	1.30	0.89	NA	1.51
Corey PG-Lactone Diol + 6.739769	ME167899	1.36	1.12	0.57	0.96	NA	0.89
Creatinine	ME167867	1.03	1.00	1.06	1.04	NA	0.88
Tiletamine	ME167869	0.93	1.20	0.92	1.23	NA	0.71
Heptanoic acid, 2-amino-, (R)-; (R)-2-Aminoheptanoic acid	ME167870	1.04	1.02	1.02	1.04	NA	0.87
4-Oxoproline	ME167881	1.02	0.92	0.92	0.86	NA	1.27
(+)-12a-Hydroxyerythynone	ME167839	1.10	1.07	1.02	1.05	NA	0.74
5,7,3^,5^-Tetrahydroxy-3,6,8,4^-tetramethoxyflavone 3^-glucoside	ME167834	1.03	1.21	0.98	1.09	NA	0.67
Urea	ME167860	0.99	1.02	1.14	1.11	NA	0.74
Levobunolol glucuronide	ME167853	1.24	1.08	0.84	1.13	NA	0.66
Metipranolol	ME167900	1.29	1.12	0.79	0.93	NA	0.78
Allodeoxycholic Acid	ME167925	1.04	1.34	0.81	1.03	NA	0.71
N-Hydroxymethylnicotinamide	ME167887	0.82	1.28	1.20	1.38	NA	0.36
Scyphostatin A	ME167916	0.90	1.30	1.00	1.20	NA	0.58
2-Amino-3-methyl-1-butanol	ME167857	1.08	1.09	0.96	1.02	NA	0.83
3^-Methoxy-E,E-dienoestrol	ME167942	0.91	1.11	0.83	1.02	NA	1.12
2-Iodophenol	ME167819	1.01	1.01	1.00	1.02	NA	0.95
Trans-2, 3, 4-Trimethoxycinnamate	ME167947	0.81	1.01	1.60	1.59	NA	0.11
3-ketosphingosine	ME167931	1.09	1.42	0.81	0.94	NA	0.65
HBA	ME167855	1.16	1.18	0.62	0.92	NA	1.03
N-Oleoyl-L-Serine	ME167913	1.14	1.33	0.87	1.12	NA	0.48
DL-?-Leucine	ME167886	1.11	1.10	0.88	0.98	NA	0.89
Diethyl Oxalpropionate	ME167890	1.30	1.78	0.80	0.84	NA	0.10
N6-Acetyl-N6-hydroxy-L-lysine	ME167864	1.35	1.03	0.99	1.16	NA	0.42
Valdecoxib	ME167827	1.04	1.12	1.05	1.07	NA	0.71
Corey PG-Lactone Diol	ME167898	1.26	1.15	0.79	0.99	NA	0.73
Glycerophospho-N-Arachidonoyl Ethanolamine	ME167919	0.83	1.11	1.24	1.29	NA	0.58
Gly Pro	ME167854	0.98	0.89	0.91	0.95	NA	1.29
Cetraxate	ME167837	1.01	1.01	1.01	1.02	NA	0.96
Indoleacrylic acid	ME167892	0.96	0.93	0.96	0.99	NA	1.17
L-Glutamic acid dibutyl ester	ME167897	1.21	1.28	1.04	1.01	NA	0.39
Senecivernine	ME167841	1.05	1.05	0.95	1.02	NA	0.91
Ursodeoxycholic acid 3-sulfate	ME167896	1.52	1.86	0.40	0.87	NA	0.10
(Z)-N-(2-hydroxyethyl)hexadec-7-enamide	ME167927	0.92	1.27	0.87	1.05	NA	0.86
3-(Pyrazol-1-yl)-L-alanine	ME167824	1.02	0.92	1.00	0.99	NA	1.08
Uric acid	ME167877	1.03	1.00	1.05	1.07	NA	0.85
Hippuric acid	ME167895	1.15	1.03	1.03	1.17	NA	0.61
L-Valine	ME167859	1.06	1.13	0.88	0.93	NA	0.97
Phe Gly Trp	ME167950	0.99	0.33	0.58	0.92	NA	2.25
DL-2-Aminooctanoic acid	ME167876	1.05	1.01	1.10	1.12	NA	0.72
o-Methyldopamine (3-methoxytyramine)	ME167891	1.09	1.06	1.05	0.99	NA	0.80
Tetrahydropalmatine	ME167856	1.06	1.28	0.84	0.98	NA	0.77
Myxothiazol Z	ME167851	1.05	0.89	1.12	1.03	NA	0.93
5,7,4^-Trihydroxyflavanone 7-sulfate	ME167826	1.01	1.13	0.98	1.04	NA	0.82
THTC	ME167879	0.98	0.96	0.96	0.96	NA	1.14
N,N-Diethylglycine	ME167889	0.99	0.85	1.24	1.15	NA	0.82
3-Methyl-L-histidine	ME167829	1.01	1.04	1.22	1.00	NA	0.73
6-methyltetrahydropterin	ME167868	0.88	0.79	0.92	0.72	NA	1.72
Celiprolol	ME167940	1.40	1.40	0.61	0.84	NA	0.60
Desmethylmianserin glucuronide	ME167843	1.02	1.14	1.06	1.13	NA	0.63
Caproic acid + 1.6348685	ME167884	0.93	0.88	1.20	1.12	NA	0.92
N2-Succinylglutamic acid	ME167937	1.13	0.60	1.37	1.04	NA	0.92
5-Methylcytidine	ME167836	0.90	0.79	0.91	1.01	NA	1.43
Azaserine	ME167934	1.08	0.93	1.02	1.14	NA	0.84
1-L-Leucyl-L-Proline	ME167885	1.06	1.13	1.04	1.11	NA	0.64
DL-pipecolic acid	ME167878	1.13	1.20	0.89	1.01	NA	0.71
Trp Phe	ME167865	1.07	1.12	1.06	1.23	NA	0.52
Uridine	ME167875	1.10	0.88	1.08	1.09	NA	0.87
methyl-10-hydroperoxy-8E,12Z,15Z-octadecatrienoate	ME167905	1.13	1.29	0.81	1.02	NA	0.68
N-palmitoyl serine	ME167908	1.15	1.23	0.84	1.17	NA	0.56
AMPA	ME167832	0.97	1.13	0.67	0.98	NA	1.21
Lysine	ME167817	1.18	0.92	1.00	1.33	NA	0.58
7-hydroxy-5-heptynoic acid	ME167812	1.04	1.04	1.00	1.00	NA	0.91
3-Isochromanone	ME167915	1.00	1.01	1.03	1.02	NA	0.94
5-Formiminotetrahydrofolic acid	ME167845	1.04	1.18	1.00	1.09	NA	0.67
L-Glutamic acid n-butyl ester + 1.5990624	ME167883	1.13	1.20	0.97	1.04	NA	0.62
1-Methyladenosine	ME167938	0.66	1.07	1.26	1.80	NA	0.33
C17 Sphinganine	ME167906	1.02	0.98	1.03	1.04	NA	0.93
AFMK	ME167894	1.04	1.15	1.10	1.33	NA	0.38
L-Arginine	ME167825	0.97	0.93	0.92	1.00	NA	1.18
Quinaprilat	ME167852	0.97	0.98	0.91	0.94	NA	1.20
S-(2-Methylpropionyl)-dihydrolipoamide-E	ME167872	1.28	0.98	0.81	0.84	NA	1.04
Caproic acid	ME167882	0.94	0.88	1.22	1.09	NA	0.93
Phe Phe Thr	ME167850	1.07	1.06	1.04	1.10	NA	0.73
Benzenamine sulfate	ME167813	0.83	0.51	1.14	1.32	NA	1.32
3-Butynoate	ME167842	1.11	0.94	0.77	1.07	NA	1.10
L-Glutamic acid n-butyl ester	ME167880	1.13	1.19	0.97	1.04	NA	0.62
(E)-2-Methylglutaconic acid	ME167846	0.98	1.02	0.94	1.15	NA	0.92
3?,11?-Dihydroxy-12-oxo-5?-cholan-24-oic Acid	ME167949	0.73	0.95	1.12	1.02	NA	1.24
Symmetric Dimethylarginine	ME167871	1.05	1.05	1.00	1.04	NA	0.86
2-Oxo-10-methylthiodecanoic acid	ME167862	0.94	0.99	0.95	0.99	NA	1.15
Isobutyronitrile	ME167866	0.97	0.96	0.88	0.89	NA	1.30
Tetrahydrocorticosterone	ME167907	1.19	1.38	0.67	0.88	NA	0.77
3-Pyridylacetic acid	ME167863	1.23	1.33	1.00	0.93	NA	0.43
LysoPE(0:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))	ME167917	0.89	1.09	1.21	1.34	NA	0.51
10-Deoxymethynolide	ME167901	1.17	1.23	0.86	0.91	NA	0.76
2S-amino-3-oxo-butanoic acid	ME167873	1.26	1.54	0.79	0.97	NA	0.31
2-oxo-3-methylvaleric acid	ME167874	1.09	1.22	0.88	1.12	NA	0.65
DL-?-Lipoic Acid	ME167946	1.02	0.98	1.09	1.02	NA	0.90
Fexofenadine	ME167922	1.02	1.21	0.92	1.14	NA	0.69
13S-hydroperoxy-9Z,11E,14Z-octadecatrienoic acid	ME167948	0.83	1.30	0.83	1.64	NA	0.42
edetate	ME167831	1.02	1.05	0.97	1.02	NA	0.93
1,6-Anhydro-?-D-glucose	ME167847	1.06	1.07	0.93	1.05	NA	0.88
N-Acetylputrescine	ME167814	1.10	1.07	0.93	0.91	NA	0.95

Factors:

F1	group:Old-Curcumin \| Time point:Post
F2	group:Old-Curcumin \| Time point:Pre
F3	group:Old-Placebo \| Time point:Post
F4	group:Old-Placebo \| Time point:Pre
F5	group:young \| Time point:Baseline
F6	group:young \| Time point:Pre

Data matrix