Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST000567)

HILIC NEGATIVE ION MODE (Analysis AN000871)

Metabolite	Structure	F1	F2	F3	F4	F5	F6
3-O-Demethylamorphigenin	ME168176	4.50	0.00	0.00	0.00	0.00	NA
2beta,7alpha,12alpha-Trihydroxy-3-oxo-5beta-cholan-24-oic Acid	ME168110	2.18	1.27	0.31	0.29	0.64	NA
PE(P-16:0/20:5(5Z,8Z,11Z,14Z,17Z))	ME168118	0.73	0.65	1.84	1.40	0.56	NA
PS(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/19:1(9Z))	ME168172	0.91	0.83	1.95	1.14	0.29	NA
Methionine	ME168112	1.07	1.18	1.59	1.18	0.00	NA
Trp His Glu	ME168109	0.88	1.47	1.96	0.57	0.10	NA
6-dehydrotestosterone 17-glucosiduronic acid	ME168066	0.86	1.24	1.81	0.77	0.34	NA
6-dehydrotestosterone 17-glucosiduronic acid - 3.373496	ME168108	0.79	1.35	1.81	0.73	0.33	NA
3?,7?,12?-Trihydroxy-24-methyl-5?-cholest-23-en-26-oic acid	ME168051	1.16	1.15	0.66	1.82	0.21	NA
Coformycin	ME168093	1.05	1.61	0.92	0.85	0.47	NA
Lactic acid	ME168098	1.24	1.57	1.03	0.53	0.48	NA
Met His Asn	ME168180	1.49	1.51	0.98	0.74	0.12	NA
1,9-dideoxyforskolin	ME168004	1.41	1.44	0.63	1.12	0.27	NA
Euparin	ME168069	1.27	1.54	0.90	0.95	0.21	NA
(S)-3-Hydroxybutyric acid	ME168071	1.31	1.49	0.84	0.98	0.25	NA
3b,16a-Dihydroxyandrostenone sulfate - 1.2323091	ME168062	1.37	1.30	1.08	1.10	0.07	NA
5-Acetylamino-6-amino-3-methyluracil	ME168104	1.17	1.33	1.13	1.00	0.30	NA
Glutaconic acid	ME168083	1.13	1.34	1.17	1.00	0.30	NA
3-Methylxanthine	ME168078	1.21	1.39	0.86	0.99	0.46	NA
Met Trp Met	ME168003	1.26	1.22	1.04	0.89	0.52	NA
13Z-hexadecenoic acid	ME168027	1.01	1.09	0.82	1.53	0.56	NA
15-hydroxy-pentacosanoic acid	ME168002	0.89	0.99	1.26	1.39	0.53	NA
26-hydroxy-hexacosanoic acid	ME167991	0.88	0.99	1.25	1.37	0.57	NA
Ascorbate 2-sulfate	ME167956	0.90	0.97	1.34	1.39	0.47	NA
MG(0:0/24:0/0:0)	ME168031	0.84	0.99	1.32	1.43	0.50	NA
Eicosanedioic acid	ME168164	0.94	1.11	1.01	1.30	0.65	NA
5?-Cholestane-3?,7?,12?,24,26-pentol	ME168030	0.86	1.11	1.15	1.24	0.68	NA
4-Sulfobenzyl alcohol	ME167962	0.86	1.08	1.22	1.31	0.57	NA
p-cresol	ME167961	0.89	1.06	1.19	1.30	0.59	NA
AFMK	ME168123	1.07	1.22	1.09	1.38	0.23	NA
Paraxanthine	ME168068	1.05	1.26	1.08	1.32	0.26	NA
2-Hydroxy-3-(4-methoxyethylphenoxy)-propanoic acid	ME168064	0.94	1.03	1.33	1.44	0.32	NA
Phenyl beta-D-glucopyranoside	ME168075	1.00	1.07	1.36	1.38	0.24	NA
Tyr Met Val	ME168158	0.96	1.48	0.63	0.98	0.86	NA
YM-201636	ME168016	1.23	1.43	0.71	0.82	0.68	NA
2Z-dodecenoic acid	ME168029	1.34	1.27	0.74	0.75	0.78	NA
9E,12Z,15Z-octadecatrienoic acid	ME168024	1.19	1.20	0.79	0.81	0.93	NA
PS(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/21:0)	ME168124	1.20	1.30	0.79	0.75	0.86	NA
3-keto valeric acid	ME168092	0.97	1.18	1.29	0.74	0.80	NA
Methyl oleate	ME167996	1.02	1.01	1.37	0.80	0.80	NA
Asp Glu His	ME168014	1.18	1.22	0.76	1.04	0.72	NA
13Z-octadecenoic acid	ME168009	1.11	1.25	0.95	1.00	0.62	NA
7-keto-stearic acid	ME168058	1.04	1.18	0.95	1.10	0.71	NA
3-oxohexacosanoic acid	ME167994	1.04	1.12	0.98	1.05	0.78	NA
MG(0:0/22:1(13Z)/0:0)	ME168023	1.02	1.15	1.02	1.05	0.75	NA
1?,25-dihydroxy-11?-(2-hydroxyethyl)vitamin D3 / 1?,25-dihydroxy-11?-(2-hydroxyethyl)cholecalciferol	ME168034	1.09	1.19	0.90	0.91	0.86	NA
PI(20:2(11Z,14Z)/18:2(9Z,12Z))	ME168113	1.08	1.17	0.97	0.89	0.84	NA
PI(22:4(7Z,10Z,13Z,16Z)/18:3(6Z,9Z,12Z))	ME168114	1.08	1.19	0.94	0.90	0.84	NA
2Z,13E-Octadecadienyl acetate	ME167992	1.01	1.26	0.90	0.94	0.84	NA
Proscillaridin A	ME168032	1.01	1.24	0.90	1.01	0.81	NA
17-oxo-20Z-hexacosenoic acid	ME168007	1.10	1.23	0.92	0.92	0.77	NA
6E,9E-octadecadienoic acid	ME168017	1.10	1.24	0.87	0.96	0.77	NA
7,11,14-Eicosatrienoic acid	ME167997	1.06	1.15	0.91	1.00	0.84	NA
Mestanolone	ME168008	1.07	1.18	0.90	0.97	0.83	NA
Stearic acid	ME167999	1.07	1.17	0.93	0.96	0.84	NA
1?-hydroxy-23,24,25,26,27-pentanorvitamin D3 / 1?-hydroxy-23,24,25,26,27-pentanorcholecalciferol	ME168000	1.05	1.19	0.92	1.02	0.79	NA
8-Prenylafzelechin 5-methyl ether	ME168020	1.04	1.18	0.93	1.04	0.78	NA
2,4-dimethyl-tetradecanoic acid	ME168021	1.08	1.19	0.92	0.98	0.78	NA
8,12,16,19-docosatetraenoic acid	ME167990	1.06	1.22	0.93	1.00	0.75	NA
5-Acetylamino-6-formylamino-3-methyluracil	ME168079	0.87	1.19	1.15	1.08	0.71	NA
1-Deacetoxy-1-Oxo-3,7-Dideacetylkhivorin	ME168045	1.03	0.89	1.10	1.12	0.88	NA
Neoabietic acid	ME168015	0.96	1.06	1.05	1.21	0.74	NA
2,4.6-Trichloroanisole	ME167952	1.02	1.03	1.06	1.15	0.74	NA
MID42238:(6R)-1?,25-dihydroxyvitamin D3 6,19-sulfur dioxide adduct / (6R)-1?,25-dihydroxycholecalcif	ME167969	0.97	1.04	1.12	1.13	0.76	NA
Deoxyribose 5-phosphate	ME168084	0.98	1.04	1.14	1.03	0.82	NA
PE(22:5(7Z,10Z,13Z,16Z,19Z)/P-18:1(11Z))	ME168116	1.02	1.02	1.16	1.06	0.75	NA
PE(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/P-18:1(9Z))	ME168115	1.05	1.08	1.08	1.06	0.72	NA
Uridine	ME168091	1.06	1.04	1.07	1.05	0.76	NA
PE(18:3(9Z,12Z,15Z)/20:3(8Z,11Z,14Z))	ME168119	1.04	1.12	1.05	0.97	0.80	NA
2,4,5-Trichlorophenoxyacetic Acid, Isooctyl Ester	ME168138	1.06	1.06	1.00	1.01	0.85	NA
5,6-Dihydrouridine	ME168080	1.08	1.04	1.04	1.02	0.80	NA
8,11,14-Docosatriynoic acid	ME168006	1.01	1.06	0.96	1.12	0.84	NA
Creatinine	ME168111	1.02	1.01	1.07	1.09	0.81	NA
Hydroxyibuprofen	ME168061	1.01	1.02	1.04	1.06	0.87	NA
Sophoracoumestan A	ME168095	1.17	1.01	1.32	1.08	0.42	NA
19-Hydroxy-8-O-methyltetrangulol	ME168100	1.15	1.03	1.19	1.06	0.56	NA
Fagomine	ME168145	1.18	0.96	1.17	1.05	0.64	NA
Hippuric acid	ME168103	1.15	0.96	1.02	1.18	0.69	NA
Tauropine	ME168097	1.15	1.04	1.07	1.09	0.65	NA
6-deoxoteasterone	ME168160	1.06	1.15	1.09	1.10	0.59	NA
NVP-BEZ235	ME168011	1.04	1.19	1.09	1.12	0.54	NA
2-Hydroxyethanesulfonate	ME168082	1.04	0.99	1.15	1.22	0.62	NA
PS(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/19:0)	ME168122	1.03	1.07	1.23	1.12	0.55	NA
(23S)-23,24,25-trihydroxyvitamin D3 / (23S)-23,24,25-trihydroxycholecalciferol - 1.2433269	ME168063	0.81	0.84	1.15	1.09	1.19	NA
Hydroquinone	ME167953	0.92	0.83	1.25	1.01	1.04	NA
3b,16a-Dihydroxyandrostenone sulfate	ME167984	0.82	0.79	1.17	1.31	1.00	NA
MG(24:1(15Z)/0:0/0:0)	ME168055	0.88	0.88	1.28	1.27	0.77	NA
7?,12?-Dihydroxy-5?-cholan-24-oic Acid	ME168065	1.24	1.12	0.74	0.67	1.15	NA
MID42262:(24R)-25-fluoro-1?,24-dihydroxy-24-methylvitamin D3 / (24R)-25-fluoro-1?,24-dihydroxy-24-me	ME167970	1.05	1.22	0.70	0.72	1.22	NA
(23S)-23,24,25-trihydroxyvitamin D3 / (23S)-23,24,25-trihydroxycholecalciferol	ME168059	0.87	0.87	1.03	0.92	1.34	NA
5,11,14-Eicosatrienoic acid, 8,9-dihydroxy-; 8,9-Dihydroxy-5,11,14-eicosatrienoic acid	ME168057	0.93	0.85	0.98	0.87	1.39	NA
16,16-dimethyl-PGA1	ME168054	1.02	0.98	0.82	0.88	1.28	NA
PI(18:1(9Z)/18:2(9Z,12Z))	ME168117	0.99	1.01	0.87	0.81	1.29	NA
MID42315:1?,25-dihydroxy-26,27-dimethyl-22-oxavitamin D3 / 1?,25-dihydroxy-26,27-dimethyl-22-oxachol	ME168041	0.97	1.02	0.92	0.91	1.18	NA
Dehydro-L-(+)-ascorbic acid dimer	ME168128	0.93	0.91	1.00	1.01	1.17	NA
His His Cys	ME168149	0.90	0.94	0.96	1.03	1.19	NA
2-Butanone, 4-[6-(sulfooxy)-2-naphthalenyl]-	ME168173	1.01	0.91	0.96	0.94	1.19	NA
Arg Arg Phe	ME168126	0.98	0.89	0.93	0.95	1.27	NA
5-?-Hydroxybutyl Hydantoin	ME168144	0.93	0.96	0.97	0.91	1.23	NA
Epoxomicin	ME168139	0.94	0.91	0.97	0.93	1.26	NA
Arg Arg Lys	ME168162	1.15	0.96	0.97	0.76	1.13	NA
DG(22:5(4Z,7Z,10Z,13Z,16Z)/22:1(13Z)/0:0)	ME168042	0.98	1.09	0.94	0.88	1.08	NA
26,27-diethyl-1?,25-dihydroxy-23-oxavitamin D3 / 26,27-diethyl-1?,25-dihydroxy-23-oxacholecalciferol	ME168033	1.00	1.11	0.86	0.84	1.16	NA
Furmecyclox	ME168157	1.02	1.15	0.89	0.80	1.09	NA
Tryptophan	ME168129	0.99	0.98	0.98	0.98	1.08	NA
9-Hydroxyphenanthrene	ME168141	0.99	0.98	1.03	0.98	1.03	NA
Indole	ME168130	0.99	1.01	1.01	0.95	1.04	NA
(3a,5b)-24-oxo-24-[(2-sulfoethyl)amino]cholan-3-yl-b-D-Glucopyranosiduronic acid	ME168134	1.11	1.00	0.86	0.94	1.07	NA
Diphenylmethylphosphine	ME168132	1.02	1.01	0.86	1.03	1.06	NA
Tauroursodeoxycholic acid	ME168106	0.45	0.30	1.74	1.38	1.39	NA
Laurencione diacetate	ME168177	0.14	0.38	0.76	0.75	3.14	NA
Asp Asn - 1.0590627	ME168156	0.48	0.51	1.12	0.56	2.45	NA
Norbixin	ME168178	0.31	0.27	0.99	0.96	2.67	NA
Epicatechin 3-O-beta-D-glucopyranoside	ME168148	0.48	0.42	0.75	0.96	2.53	NA
AMCC - 3.3688588	ME168107	0.34	0.60	0.56	0.88	2.73	NA
Arg Leu Tyr	ME168182	0.51	0.47	0.62	0.70	2.79	NA
Scillaren A	ME168147	0.49	0.55	0.64	0.75	2.67	NA
16-Feruloyloxypalmitate	ME168184	0.86	0.81	0.50	0.54	2.27	NA
MID42391:26,27-diethyl-1?,25-dihydroxy-20,21-didehydro-23-oxavitamin D3 / 26,27-diethyl-1?,25-dihydr	ME168060	0.88	1.12	0.57	0.77	1.61	NA
pregnenolone sulfate	ME167971	0.68	0.66	0.72	0.85	2.15	NA
AMCC	ME168105	0.61	0.82	0.67	0.84	2.11	NA
N-acetyl-LTE4	ME168168	0.55	0.81	0.69	0.94	2.07	NA
Scandoside methyl ester	ME167988	0.59	0.67	0.78	1.19	1.88	NA
Prasterone sulfate	ME167975	0.62	0.67	0.82	0.99	1.99	NA
5?-Androstan-3?-ol-17-one sulfate	ME167981	0.70	0.78	0.82	0.92	1.84	NA
4-Ketonostoxanthin 3-sulfate	ME168151	0.64	0.77	0.80	0.94	1.92	NA
Marinobufagenin	ME167982	0.68	0.72	0.83	0.94	1.90	NA
Asp Asn	ME168154	0.66	0.66	0.95	1.09	1.75	NA
cyclo-Dopa-glucuronylglucoside	ME167973	0.69	0.79	0.85	1.02	1.72	NA
Pregnanolone sulfate	ME167979	0.68	0.79	0.89	0.97	1.74	NA
Deoxycholic acid glycine conjugate	ME168171	0.88	0.59	0.76	0.87	1.95	NA
12-hydroxy-10-octadecynoic acid	ME168048	0.81	0.77	0.63	0.94	1.88	NA
Methylprednisone	ME168155	0.89	0.84	0.69	0.84	1.75	NA
SC-514	ME168175	0.91	0.84	0.63	0.95	1.67	NA
2-Carboxy-2-hydroxy-8-carboxychromene	ME168143	0.62	0.77	1.04	0.61	2.02	NA
C16-OH Sulfatide	ME167986	0.69	0.99	1.00	0.69	1.65	NA
Lys Met His	ME167987	0.81	0.78	1.01	0.78	1.67	NA

Factors:

F1	groups:Old-Curcumin \| Time point:Post
F2	groups:Old-Curcumin \| Time point:Pre
F3	groups:Old-Placebo \| Time point:Post
F4	groups:Old-Placebo \| Time point:Pre
F5	groups:young \| Time point:Baseline
F6	groups:young \| Time point:Pre

Data matrix