Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST000876)

(Analysis AN001413)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12
Adenine	ME226355	5.04	0.61	0.60	0.50	0.84	0.99	0.63	0.43	0.75	0.50	1.13	0.48
Hippuric acid	ME226293	0.20	0.33	3.21	1.74	0.32	0.24	0.21	1.74	0.75	0.31	2.74	0.59
Guanosine	ME226329	0.33	2.82	0.78	0.45	0.30	0.49	1.20	0.39	4.27	0.67	0.28	0.51
Inosine	ME226312	0.59	1.68	0.55	0.41	0.53	1.05	1.17	1.16	2.94	1.27	0.57	0.54
Cytosine	ME226334	1.06	0.32	2.99	0.36	0.26	0.38	0.22	0.24	0.55	0.62	1.17	2.42
NAD	ME226349	3.65	0.13	0.55	0.26	0.44	3.70	0.28	1.30	0.40	0.40	1.14	0.37
UDP-Glucose	ME226310	2.96	0.28	0.62	0.35	0.58	3.00	0.26	1.35	0.51	NA	1.45	0.32
Allantoin	ME226299	1.89	0.58	0.78	0.73	0.60	2.36	0.56	1.12	0.21	0.88	1.08	1.11
AMP	ME226342	2.26	0.47	0.88	0.65	0.57	2.46	0.34	1.24	0.82	0.61	1.65	0.52
IMP	ME226341	1.80	0.76	1.14	0.51	0.72	2.58	0.44	1.07	0.98	0.68	1.41	0.46
Glutathione	ME226360	1.17	0.54	1.29	0.63	NA	1.50	0.79	NA	1.08	NA	NA	NA
Palmitoyl Carnitine	ME226337	0.12	0.99	1.19	1.39	1.82	0.19	1.81	1.52	1.25	0.47	1.43	0.40
Stearoyl Carnitine	ME226347	0.27	0.81	1.52	1.00	2.23	0.18	2.23	1.14	1.17	0.37	1.52	0.28
4-Pyridoxic Acid	ME226336	1.34	1.41	1.07	0.50	0.50	0.46	0.41	0.33	1.82	1.43	0.89	1.42
cAMP	ME226345	0.82	1.59	0.89	0.57	0.55	0.17	0.63	0.49	1.77	2.47	0.52	1.26
GABA	ME226315	0.99	0.70	0.88	1.23	0.96	1.16	0.60	0.70	0.86	2.68	0.72	0.76
Neopterin	ME226348	NA	0.79	0.23	1.05	0.37	1.33	1.50	0.85	0.44	1.46	1.08	1.45
Sorbitol	ME226281	0.87	0.55	0.66	0.93	0.66	1.14	0.64	0.64	0.74	0.63	0.84	2.35
S-5-Adenosyl-L-Methionine Chloride	ME226303	0.51	0.61	1.47	0.87	0.41	1.77	0.39	1.37	1.37	0.89	1.90	0.71
Homogentisic acid	ME226313	2.16	0.73	0.96	0.89	1.41	0.72	0.68	0.85	1.28	0.99	0.49	0.92
Chenodeoxycholic Acid	ME226284	1.69	1.65	0.75	0.82	0.55	1.13	0.77	0.96	1.33	0.79	0.63	0.96
Taurochenodeoxycholic Acid	ME226323	1.73	2.04	0.47	1.00	0.44	0.53	1.09	1.49	0.95	0.54	1.02	0.85
Glycocholic Acid	ME226320	1.27	1.83	0.73	0.85	0.52	0.74	1.07	1.41	0.88	0.71	0.76	1.11
Taurocholic Acid	ME226339	1.43	1.68	0.49	1.12	0.55	0.42	1.05	1.34	1.20	0.84	0.86	1.00
3-Hydroxyanthranilic acid	ME226325	1.06	NA	0.81	1.09	1.27	1.20	1.04	1.33	0.44	1.30	0.83	0.82
Serine	ME226271	0.80	0.74	0.72	1.02	1.61	1.11	1.34	1.33	1.45	1.41	0.60	0.43
Trimethylamine-N-Oxide	ME226298	0.88	0.78	1.15	0.89	1.90	0.64	1.00	1.15	0.93	1.39	0.60	0.84
Niacinamide	ME226324	0.96	0.91	1.11	1.21	0.93	0.93	1.32	1.67	0.69	0.46	1.23	0.79
Adenosine	ME226354	0.75	1.21	1.19	1.84	0.38	0.98	1.20	1.12	0.56	0.73	1.23	0.91
D-Ribose 5-phosphate	ME226327	1.20	0.71	1.32	2.02	0.83	0.86	1.10	0.95	0.81	0.55	1.31	0.67
DimethylGlycine	ME226308	0.90	0.76	1.52	0.94	1.68	0.61	1.09	0.53	1.29	0.72	1.05	0.96
Uracil	ME226309	1.24	0.80	1.28	1.34	1.37	0.55	0.76	0.58	1.68	1.10	0.49	0.90
Myristoyl Carnitine	ME226344	0.58	1.33	1.04	1.39	1.24	0.58	1.29	1.23	1.18	0.98	1.06	0.55
Cystathionine	ME226343	0.88	1.19	0.79	0.86	1.41	1.32	1.60	1.06	0.70	0.91	0.70	0.79
Sucrose	ME226297	0.85	0.96	1.08	0.82	0.76	1.57	0.66	0.74	1.26	1.02	1.21	1.03
Spermidine	ME226331	0.99	0.76	0.90	1.46	0.87	1.85	0.96	1.10	0.71	1.01	1.01	0.69
L-Glutamic Acid	ME226285	0.88	0.68	0.89	1.11	1.09	1.35	1.02	1.21	0.76	0.88	1.33	0.91
S-Adenosyl-L-Homocysteine	ME226346	0.91	0.71	1.00	1.23	0.86	1.63	0.99	1.13	0.89	0.80	1.38	0.74
5-Hydroxyindole-3-acetic acid	ME226333	1.15	0.65	1.51	1.08	0.82	0.87	0.61	1.09	1.23	0.77	0.86	1.19
Glycine	ME226261	0.89	0.86	0.92	0.69	1.37	0.97	0.99	1.30	1.24	0.99	1.07	0.85
Guanidinoacetic Acid	ME226301	0.98	0.92	1.47	0.71	1.44	0.67	0.85	1.22	1.26	0.89	1.16	0.72
Dodecanoyl Carnitine	ME226326	1.33	1.46	1.06	1.33	0.98	0.54	1.14	0.95	1.34	1.19	0.70	0.50
L-5-Hydroxytryptophan	ME226340	1.15	1.15	0.96	1.17	0.96	0.88	1.29	0.66	0.97	1.36	0.63	0.91
Acetoacetic acid	ME226259	1.58	1.27	1.00	1.03	1.04	0.59	1.10	0.75	1.31	1.31	0.55	0.74
Octanoylcarnitine	ME226319	1.56	1.23	1.03	1.05	1.01	0.59	1.02	0.82	1.14	1.28	0.61	0.83
Decanoylcarnitine	ME226321	1.29	1.12	1.04	0.98	1.01	0.68	1.05	1.00	1.18	1.21	0.70	0.88
Hexanoylcarnitine	ME226330	1.34	1.19	1.02	1.06	0.92	0.69	1.02	0.92	1.02	1.22	0.70	0.95
Kynurenic Acid	ME226338	1.39	0.91	1.31	1.21	0.87	0.84	0.83	0.72	0.63	0.98	0.97	1.17
2-Aminoisobutyric acid	ME226302	1.21	1.12	0.82	1.33	1.14	1.17	1.22	0.84	0.73	0.98	0.77	0.83
Creatine	ME226270	1.29	1.07	0.85	1.08	0.81	1.47	1.15	1.02	0.83	0.94	0.83	0.83
Xanthosine	ME226332	1.52	0.89	0.87	0.99	0.75	1.42	0.82	1.00	0.74	1.06	1.21	0.87
Ornithine	ME226275	1.18	1.20	0.87	1.08	1.00	1.08	0.93	0.98	0.67	0.98	1.29	0.87
Aspartate	ME226288	1.16	0.77	0.78	0.90	1.28	1.33	0.80	1.16	0.96	0.89	1.13	0.92
Glyceraldehyde	ME226263	1.14	1.01	0.93	0.91	0.97	1.44	0.86	0.95	0.91	0.87	1.23	0.89
Myoinositol	ME226290	0.91	0.93	0.98	1.15	0.98	1.26	0.80	0.91	0.80	1.24	1.13	0.96
Xanthine	ME226295	1.08	0.82	1.05	1.14	0.99	1.22	0.96	0.96	0.79	1.27	1.06	0.83
Hypoxanthine	ME226294	1.05	0.75	1.08	0.79	1.03	1.29	0.90	1.28	0.82	1.19	1.04	0.89
Taurine	ME226264	1.19	0.82	1.02	0.94	1.02	1.18	0.88	1.13	0.62	0.93	1.18	1.04
Carnosine	ME226318	1.50	1.15	0.85	0.92	0.74	0.97	1.14	0.80	0.92	0.95	1.10	0.98
Gamma-Glutamylcysteine	ME226287	0.96	1.14	0.86	0.86	0.79	1.22	0.77	0.98	0.98	0.98	1.09	1.19
Choline	ME226278	1.03	0.93	1.02	1.12	1.08	1.02	1.11	0.89	0.91	0.69	1.11	1.04
Betaine	ME226267	1.00	0.81	1.21	0.96	1.19	0.87	1.05	0.84	1.01	0.76	1.17	1.06
Phosphoethanolamine	ME226296	0.92	0.93	1.32	0.98	1.07	0.89	1.00	0.83	1.01	0.81	1.18	1.03
Normetanephrine	ME226353	1.09	0.97	1.04	1.11	0.80	0.75	1.02	0.72	1.01	1.09	1.07	1.17
Succinate	ME226291	1.04	1.11	1.02	0.94	1.01	0.79	0.89	0.87	0.92	0.90	1.08	1.21
3-OH-DL-KYNURENINE	ME226335	0.88	1.14	1.18	1.11	1.06	0.93	1.07	1.11	0.81	0.99	1.06	0.82
1-methylhistamine	ME226350	0.92	1.15	1.19	1.05	1.17	0.66	0.94	0.83	1.07	1.06	1.01	0.97
Creatinine	ME226272	0.88	0.97	1.12	0.94	1.01	0.78	1.04	1.12	1.10	1.07	0.95	1.01
Asymmetric dimethylarginine	ME226307	1.02	1.19	1.22	0.80	1.04	1.00	0.94	0.86	0.93	1.25	0.91	0.92
Proline	ME226260	0.90	1.36	1.31	0.80	0.89	1.15	0.76	0.92	0.97	1.00	1.08	0.93
Citrulline	ME226280	1.00	1.35	1.08	0.92	0.87	1.05	0.85	0.87	0.99	0.95	1.11	0.98
Valine	ME226258	1.02	1.26	1.14	1.08	0.98	1.07	0.99	0.91	0.91	0.91	1.05	0.84
Isobutyrylcarnitine	ME226317	1.07	1.22	1.07	0.73	0.79	1.04	1.00	1.19	0.98	1.23	0.82	0.93
deoxycytidine	ME226322	1.20	1.27	1.03	0.98	0.81	0.99	1.03	1.00	0.83	1.03	0.83	1.00
Propionylcarnitine	ME226311	1.19	1.27	1.03	0.91	0.76	0.99	1.04	1.10	0.86	1.12	0.75	0.99
Acetylcarnitine	ME226289	1.23	1.00	1.04	1.12	0.83	0.71	1.06	0.97	0.92	1.10	0.88	1.06
Carnitine	ME226273	1.14	0.89	1.02	0.88	0.87	1.03	1.01	1.10	0.99	1.09	0.84	1.07
Cytidine	ME226316	1.16	0.95	0.98	0.95	0.86	0.86	1.12	1.04	0.99	1.17	0.80	1.06
Isoleucine	ME226279	1.31	1.11	1.03	1.19	0.93	0.95	1.08	0.98	0.96	0.92	0.98	0.78
Arachidyl Carnitine	ME226352	1.11	1.14	1.00	0.92	0.96	0.94	1.25	0.94	0.97	1.05	0.97	0.87
Threonine	ME226266	1.16	1.08	1.07	1.03	0.97	0.96	1.11	0.94	0.84	0.93	1.08	0.92
L-Methionine	ME226286	1.20	1.01	1.11	0.97	1.15	1.14	0.87	0.88	0.98	0.88	1.09	0.86
Phenylalanine	ME226276	1.15	1.03	0.96	0.98	1.04	1.16	0.93	0.94	1.03	0.95	1.01	0.91
L-Kynurenine	ME226304	1.10	1.11	1.05	1.00	1.04	1.03	0.97	0.87	0.99	0.99	1.01	0.92
Histidine	ME226274	1.13	1.07	1.04	0.93	0.94	1.06	0.92	0.93	1.03	1.02	1.11	0.90
Tryptophan	ME226283	1.07	1.07	1.02	0.96	1.00	1.05	0.99	0.95	1.01	0.98	1.09	0.91
Cysteine	ME226277	1.11	1.00	1.06	0.97	0.91	1.05	0.96	1.02	0.98	0.99	0.97	0.99
Leucine	ME226268	1.10	1.10	1.06	0.94	0.98	1.11	1.01	1.04	1.02	1.03	0.91	0.84
Lysine	ME226262	1.05	1.09	1.01	1.03	0.96	1.10	0.97	1.07	0.98	1.01	0.95	0.89
Tyrosine	ME226265	0.96	1.15	0.97	0.96	0.95	0.93	0.94	0.96	1.09	1.21	1.06	0.91
Arginine	ME226269	1.05	1.07	1.00	0.89	0.94	0.95	0.97	0.99	1.24	1.01	0.98	0.96
Glutamine	ME226256	1.05	1.05	1.09	0.97	1.08	0.86	0.93	1.00	1.07	1.05	1.03	0.91
Pantothenic Acid	ME226314	0.95	0.91	0.80	0.91	1.07	1.08	1.02	1.09	0.93	1.00	0.82	1.21
Symmetric dimethylarginine	ME226306	0.92	0.84	0.91	0.93	1.09	1.06	1.00	1.18	1.09	1.12	0.87	0.99
Alanine	ME226257	0.91	1.01	0.93	0.95	1.05	1.03	0.85	1.13	0.98	1.06	1.09	1.00
Asparagine	ME226282	0.99	0.93	0.93	1.06	1.06	1.17	0.97	1.11	1.01	1.00	1.02	0.88
Aminodipic Acid	ME226305	1.04	1.48	1.55	0.72	1.01	0.98	1.00	0.81	0.90	0.94	0.98	0.79
Isovalerylcarnitine	ME226328	1.02	1.56	1.09	0.93	0.83	0.89	1.07	1.06	1.01	1.19	0.79	0.78
D-Glucuronic acid	ME226300	1.20	1.49	1.12	0.87	0.95	0.79	0.68	0.81	0.70	1.22	0.82	1.17
Hydroxyproline	ME226292	1.34	1.38	0.88	0.83	1.29	0.85	0.74	0.97	0.96	0.98	1.10	0.84

Factors:

F1	L-serine (mg/kg/day):100 \| time point (weeks):6
F2	L-serine (mg/kg/day):200 \| time point (weeks):52
F3	L-serine (mg/kg/day):200 \| time point (weeks):9
F4	L-serine (mg/kg/day):300 \| time point (weeks):12
F5	L-serine (mg/kg/day):400 \| time point (weeks):15
F6	L-serine (mg/kg/day):400 \| time point (weeks):18
F7	L-serine (mg/kg/day):400 \| time point (weeks):21
F8	L-serine (mg/kg/day):400 \| time point (weeks):30
F9	L-serine (mg/kg/day):400 \| time point (weeks):38
F10	L-serine (mg/kg/day):400 \| time point (weeks):44
F11	L-serine (mg/kg/day):50 \| time point (weeks):3
F12	L-serine (mg/kg/day):- \| time point (weeks):-

Data matrix