Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST001253)

(Analysis AN002079)

Metabolite	Structure	F1	F2	F3	F4
guanosine	ME293318	0.03	0.02	4.70	0.14
guanosine 5^- monophosphate (5^-GMP)	ME293319	0.08	0.08	2.63	1.31
serotonin	ME293253	1.90	0.21	2.30	0.31
trimethylamine N-oxide	ME293310	2.51	1.32	0.35	0.23
histamine	ME293210	2.18	0.97	0.84	0.41
imidazole propionate	ME293211	1.70	1.07	0.50	0.82
spermidine	ME293247	1.74	1.40	0.35	0.62
butyrylcarnitine (C4)	ME293289	1.85	1.40	0.56	0.44
1-methylnicotinamide	ME293277	1.80	1.20	0.66	0.56
methionine sulfone	ME293236	1.82	1.29	0.57	0.53
methyl indole-3-acetate	ME293356	2.80	0.58	0.91	0.30
S-methylmethionine	ME293239	2.56	0.36	1.07	0.53
trans-urocanate	ME293214	1.99	0.43	1.31	0.68
adenine	ME293314	1.66	0.74	1.39	0.58
pyridoxal	ME293284	1.64	0.60	1.42	0.68
formiminoglutamate	ME293209	1.09	2.42	0.24	0.27
S-methylcysteine sulfoxide	ME293238	1.68	2.00	0.23	0.25
guanidinosuccinate	ME293202	1.51	1.69	0.39	0.51
(N(1) + N(8))-acetylspermidine	ME293242	1.43	1.48	0.51	0.65
4-hydroxybutyrate (GHB)	ME293302	0.94	1.64	0.45	0.85
putrescine	ME293246	0.92	1.69	0.65	0.71
N1-Methyl-4-pyridone-3-carboxamide	ME293278	1.19	1.78	0.43	0.61
2-aminoheptanoate	ME293300	1.20	1.59	0.68	0.59
1-methyl-4-imidazoleacetate	ME293203	1.07	1.69	0.73	0.57
N-methyl-GABA	ME293188	1.11	1.70	0.63	0.60
N2,N2-dimethylguanosine	ME293320	0.26	2.21	0.45	0.80
cysteinylglycine disulfide	ME293193	0.68	1.99	0.82	0.51
N4-acetylcytidine	ME293329	0.64	2.11	0.38	0.70
uracil	ME293332	0.71	2.12	0.49	0.58
2^-O-methylcytidine	ME293322	0.42	1.90	0.63	0.85
N1-methyladenosine	ME293316	0.61	1.80	0.64	0.81
N1-methylinosine	ME293313	0.65	1.90	0.49	0.80
anserine	ME293207	0.18	0.60	0.61	2.05
cysteine	ME293233	0.26	0.81	0.55	1.86
N-alpha-acetylornithine	ME293266	0.34	0.92	0.81	1.58
carnosine	ME293208	0.34	0.61	0.79	1.84
thioproline	ME293351	0.44	0.67	0.88	1.68
N-acetylglucosaminylasparagine	ME293275	0.94	0.91	0.33	1.51
histidine betaine (hercynine)	ME293353	0.47	1.01	0.36	1.69
phosphate	ME293285	0.51	0.97	0.51	1.62
gamma-glutamyl-epsilon-lysine	ME293337	0.15	0.39	1.60	1.64
adenosine 5^-monophosphate (AMP)	ME293315	0.69	0.71	1.84	0.91
gamma-glutamylmethionine	ME293345	0.86	0.56	1.82	0.94
homostachydrine	ME293354	0.65	0.68	1.60	1.11
N-acetyl-aspartyl-glutamate (NAAG)	ME293187	0.56	0.80	1.57	1.08
cytidine 5^-monophosphate (5^-CMP)	ME293327	0.73	0.42	1.77	1.16
N-acetyl-3-methylhistidine	ME293213	0.59	0.50	1.87	1.13
cystathionine	ME293232	0.58	0.56	1.69	1.18
nicotinamide N-oxide	ME293280	0.60	0.53	1.77	1.15
glutarylcarnitine (C5-DC)	ME293225	0.70	1.61	0.84	0.79
homocitrulline	ME293264	0.90	1.57	0.92	0.65
3-methylcytidine	ME293323	0.64	1.34	1.14	0.86
choline phosphate	ME293305	0.71	1.42	1.08	0.79
dimethylarginine (SDMA + ADMA)	ME293262	0.73	1.48	0.71	0.96
cytosine	ME293328	0.58	1.49	0.97	0.88
gamma-glutamylglutamate	ME293339	0.66	1.32	0.84	1.04
7-methylguanine	ME293317	0.68	1.41	0.92	0.91
malonylcarnitine	ME293299	0.74	1.35	0.90	0.94
argininosuccinate	ME293260	0.37	1.35	0.77	1.24
glycerol 3-phosphate	ME293303	0.63	1.60	0.43	1.08
choline	ME293304	0.75	1.35	0.60	1.11
glycerophosphoserine	ME293308	0.65	1.44	0.52	1.15
nicotinate ribonucleoside	ME293281	0.41	1.29	0.44	1.46
glutathione, oxidized (GSSG)	ME293194	0.57	1.39	0.37	1.33
N6-carboxyethyllysine	ME293229	0.58	1.26	0.54	1.32
succinylcarnitine (C4-DC)	ME293286	0.69	1.22	0.51	1.31
N-trimethyl 5-aminovalerate	ME293227	1.03	1.25	0.67	0.98
phenylacetylglycine	ME293334	0.95	1.21	0.74	1.01
glycerophosphorylcholine (GPC)	ME293307	1.02	1.12	0.60	1.13
glutamate	ME293185	0.89	1.15	0.72	1.11
glycerophosphoethanolamine	ME293306	0.88	1.20	0.61	1.15
cysteine-glutathione disulfide	ME293192	0.67	1.03	0.85	1.26
methylphosphate	ME293311	1.16	0.76	0.73	1.25
adipoylcarnitine (C6-DC)	ME293294	0.95	0.92	0.76	1.24
ergothioneine	ME293352	0.93	0.81	0.68	1.38
N6,N6,N6-trimethyllysine	ME293228	0.83	0.89	0.71	1.37
1-methylhistamine	ME293204	1.48	1.00	1.20	0.59
S-1-pyrroline-5-carboxylate	ME293190	1.32	1.12	1.06	0.68
indolepropionate	ME293250	1.37	1.09	1.10	0.64
pyroglutamine	ME293189	1.37	1.10	1.12	0.63
isovalerylcarnitine (C5)	ME293219	1.47	0.88	1.08	0.76
kynurenine	ME293251	1.36	0.85	1.09	0.85
tiglylcarnitine (C5:1-DC)	ME293221	1.35	0.85	1.02	0.90
valine	ME293222	1.61	0.94	0.92	0.73
leucine	ME293220	1.52	0.95	0.96	0.76
picolinate	ME293252	1.56	0.90	0.94	0.78
gamma-glutamylleucine	ME293344	1.46	1.02	1.01	0.70
gamma-glutamylcitrulline	ME293338	1.38	1.04	0.94	0.78
isoleucine	ME293218	1.41	1.05	0.92	0.76
suberoylcarnitine (C8-DC)	ME293297	1.20	1.06	0.83	0.93
dimethyl sulfone	ME293350	1.36	1.35	0.81	0.61
4-guanidinobutanoate	ME293201	1.37	1.24	0.84	0.68
3-hydroxybutyrylcarnitine (1)	ME293291	1.42	1.19	0.82	0.70
indolelactate	ME293249	1.44	1.23	0.77	0.69
carboxyethyl-GABA	ME293184	1.23	1.32	0.69	0.79
pipecolate	ME293230	1.14	1.28	0.73	0.85
3-hydroxybutyrylcarnitine (2)	ME293292	1.22	1.20	0.93	0.75
gamma-glutamyltryptophan	ME293347	1.12	1.30	0.90	0.75
ornithine	ME293269	1.18	1.33	0.80	0.75
prolylglycine	ME293335	1.48	0.44	1.24	1.01
2-methylbutyrylcarnitine (C5)	ME293215	1.13	0.65	1.11	1.14
3-methylcrotonylglycine	ME293216	1.19	0.46	1.15	1.23
sarcosine	ME293198	0.73	0.98	1.62	0.80
hydroxymethylpyrimidine	ME293283	0.97	1.10	1.59	0.58
indolin-2-one	ME293355	0.91	1.10	1.48	0.68
gamma-glutamylhistidine	ME293342	0.99	0.87	1.48	0.82
propionylcarnitine (C3)	ME293290	0.96	0.77	1.61	0.84
carnitine	ME293287	1.15	0.80	1.32	0.87
5-methylthioadenosine (MTA)	ME293244	1.21	0.79	1.48	0.75
1-ribosyl-imidazoleacetate	ME293205	1.10	0.75	1.47	0.86
isobutyrylcarnitine (C4)	ME293217	1.11	0.83	1.43	0.81
argininate	ME293258	1.39	0.75	1.52	0.65
biotin	ME293276	1.21	0.96	1.43	0.64
dimethylglycine	ME293196	1.06	1.11	1.24	0.74
N-acetylputrescine	ME293245	1.06	1.23	1.19	0.66
3-ureidopropionate	ME293330	0.99	1.22	1.08	0.78
5-hydroxylysine	ME293224	1.03	1.12	1.06	0.85
citrulline	ME293261	1.09	1.11	0.96	0.88
urea	ME293273	1.23	0.74	1.18	0.96
gamma-glutamylvaline	ME293349	1.03	0.86	1.18	0.99
serine	ME293199	1.06	0.85	1.16	0.99
2-aminobutyrate	ME293191	1.03	0.89	1.25	0.92
trigonelline (N^-methylnicotinate)	ME293282	0.98	0.90	1.31	0.91
glutamine	ME293186	1.09	1.02	1.00	0.94
phenylalanine	ME293241	1.04	0.95	1.05	0.98
acetylcarnitine (C2)	ME293293	1.00	1.00	1.14	0.92
anthranilate	ME293248	1.08	1.01	1.18	0.85
4-acetamidobutanoate	ME293243	1.21	1.05	1.13	0.75
gamma-glutamylphenylalanine	ME293346	1.16	1.02	1.10	0.83
4-imidazoleacetate	ME293206	1.19	0.95	1.09	0.88
gamma-glutamylglutamine	ME293340	1.13	0.94	1.10	0.91
gamma-glutamylisoleucine	ME293343	1.11	0.92	1.19	0.88
tryptophan	ME293254	1.20	0.91	1.17	0.85
asparagine	ME293178	0.95	0.94	1.11	1.02
N-methylproline	ME293267	0.94	0.91	1.08	1.06
proline	ME293271	0.86	0.97	1.20	0.99
5-aminovalerate	ME293223	0.88	1.02	1.12	0.98
taurine	ME293240	0.82	1.04	1.08	1.03
creatinine	ME293183	0.77	0.98	1.01	1.15
5-methyl-2^-deoxycytidine	ME293324	0.93	0.84	0.98	1.18
cytidine	ME293326	0.95	0.81	1.03	1.17
deoxycarnitine	ME293288	0.95	0.87	1.01	1.13
lysine	ME293226	0.94	0.92	0.98	1.11
nicotinamide	ME293279	0.95	0.93	0.99	1.09
creatine	ME293182	0.76	1.12	1.02	1.04
pimeloylcarnitine/3-methyladipoylcarnitine (C7-DC)	ME293296	0.76	1.16	1.03	1.00
hydroxyasparagine	ME293180	0.84	1.23	0.99	0.92
N-acetylglucosamine/N-acetylgalactosamine	ME293274	0.80	1.27	0.97	0.92
aspartate	ME293179	0.93	1.14	0.91	0.99
2-hydroxyglutarate	ME293301	0.90	1.14	1.00	0.95
N-monomethylarginine	ME293268	0.91	1.16	0.95	0.95
hexanoylcarnitine (C6)	ME293295	0.82	1.14	1.18	0.89
N-acetyl-1-methylhistidine	ME293212	0.62	1.15	1.17	1.01
2^-deoxycytidine	ME293321	0.75	0.54	1.36	1.31
5-methylcytidine	ME293325	0.56	0.73	1.15	1.39
arginine	ME293259	0.62	0.72	1.08	1.41
5-methylthioribose	ME293231	0.52	0.59	1.36	1.40
homoarginine	ME293263	0.49	0.57	1.17	1.54
threonine	ME293200	0.94	0.81	1.25	1.04
gamma-glutamyltyrosine	ME293348	0.84	0.86	1.32	1.02
inosine 5^-monophosphate (IMP)	ME293312	0.86	0.86	1.29	1.03
betaine	ME293195	0.75	0.92	1.32	1.02
methionine sulfoxide	ME293237	0.83	0.99	1.34	0.91
stachydrine	ME293357	0.86	0.82	1.52	0.92
methionine	ME293235	0.85	0.77	1.48	0.99
uridine 5^-monophosphate (UMP)	ME293333	0.77	0.77	1.47	1.03
cysteine sulfinic acid	ME293234	0.96	0.63	1.35	1.11
N-acetylarginine	ME293265	0.82	0.67	1.42	1.12
3-methoxytyrosine	ME293255	0.63	0.80	1.32	1.19
beta-alanine	ME293331	0.54	0.93	1.25	1.18
gamma-glutamylglycine	ME293341	0.61	0.89	1.24	1.17
gamma-glutamyl-alpha-lysine	ME293336	0.68	0.77	1.21	1.25
pro-hydroxy-pro	ME293270	0.63	0.77	1.19	1.29
glycine	ME293197	0.76	0.87	1.14	1.16
N-acetylasparagine	ME293181	0.69	0.84	1.20	1.20
2-butenoylglycine	ME293298	0.84	0.72	1.12	1.25
phosphoethanolamine	ME293309	0.75	0.71	1.08	1.34
2-oxoarginine	ME293257	0.91	0.67	1.22	1.19
trans-4-hydroxyproline	ME293272	0.86	0.75	1.23	1.15
tyrosine	ME293256	0.87	0.82	1.19	1.11

Factors:

F1	diabetes:db/db \| time of day:ZT17
F2	diabetes:db/db \| time of day:ZT5
F3	diabetes:db/m \| time of day:ZT17
F4	diabetes:db/m \| time of day:ZT5

Data matrix