Clustering data with hclust algorithm for (Study ST001507)
(Analysis AN002498)Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
---|---|---|---|---|---|---|---|---|---|
IMP | ME361781 | 1.31 | 0.45 | 0.98 | 0.43 | 1.89 | 0.72 | 1.65 | 0.63 |
3-hydroxybutyric acid | ME361604 | 1.62 | 0.47 | 1.54 | 0.40 | 1.51 | 0.61 | 1.30 | 0.59 |
acetyl-cysteine | ME361747 | 1.80 | 0.43 | 1.42 | 0.42 | 0.98 | 0.75 | 1.36 | 0.58 |
Adenosine + 3 | ME361826 | 0.46 | 0.72 | 0.43 | 1.02 | 0.91 | 1.77 | 0.61 | 2.08 |
Hydroxyproline | ME361874 | 0.50 | 0.90 | 0.64 | 0.94 | 0.75 | 1.74 | 0.78 | 1.74 |
Hydroxyproline + 1 | ME361875 | 0.34 | 0.94 | 0.55 | 0.98 | 0.67 | 1.82 | 0.66 | 2.01 |
Palmitic acid+3 | ME361709 | 0.52 | 0.60 | 0.48 | 0.74 | 1.10 | 2.10 | 0.77 | 1.25 |
5-Oxoproline (pyroglutamic Acid) +1 | ME361818 | 0.31 | 0.89 | 0.33 | 0.64 | 1.17 | 1.80 | 1.18 | 1.69 |
Glycerate | ME361773 | 0.40 | 0.94 | 0.46 | 0.98 | 1.01 | 1.72 | 1.12 | 1.38 |
Lactate+1 | ME361691 | 0.43 | 1.43 | 0.44 | 1.24 | 0.67 | 1.79 | 0.63 | 1.36 |
acetyl-aspartate (N) | ME361744 | 0.78 | 1.53 | 0.63 | 1.08 | 0.68 | 1.38 | 0.66 | 1.23 |
Alanine+1 | ME361620 | 0.55 | 1.57 | 0.52 | 1.19 | 0.62 | 1.45 | 0.62 | 1.45 |
Cystathionine | ME361763 | 0.52 | 1.22 | 0.62 | 1.47 | 0.47 | 1.32 | 0.93 | 1.41 |
Glutamate +1 | ME361670 | 0.72 | 1.15 | 0.81 | 1.25 | 0.56 | 1.16 | 0.64 | 1.68 |
aKG +5 | ME361618 | 0.49 | 1.12 | 0.67 | 0.48 | 0.49 | 1.46 | 1.02 | 0.84 |
CDP | ME361757 | 0.47 | 0.97 | 0.39 | 1.10 | 0.61 | 1.91 | 0.78 | 0.95 |
Arginine | ME361624 | 0.75 | 0.72 | 0.93 | 1.19 | 0.82 | 0.70 | 2.00 | 0.88 |
Hydroxyproline + 2 | ME361876 | 1.18 | 0.69 | 1.34 | 0.96 | 0.50 | 1.62 | 1.50 | 0.56 |
G6P + 2 | ME361657 | 0.70 | 1.70 | 1.21 | 1.25 | 0.55 | 1.25 | 0.71 | 0.59 |
NADPH | ME361705 | 1.18 | 1.52 | 0.80 | 0.99 | 0.46 | 1.44 | 0.73 | 0.85 |
Sedoheptulose-7-phosphate (D) + 1 | ME361879 | 0.78 | 1.39 | 0.92 | 1.03 | 0.88 | 1.35 | 0.98 | 0.66 |
ATP | ME361635 | 0.93 | 1.20 | 0.96 | 1.00 | 0.80 | 1.49 | 0.90 | 0.71 |
Guanine | ME361775 | 0.98 | 1.19 | 0.90 | 0.94 | 0.77 | 1.33 | 1.03 | 0.85 |
NADH | ME361703 | 0.86 | 1.26 | 1.08 | 0.53 | 0.61 | 0.91 | 1.21 | 0.51 |
S-Adenosyl-L-methionine | ME361803 | 1.27 | 1.04 | 1.27 | 1.09 | 0.91 | 0.72 | 0.96 | 0.75 |
Serotonin (nv) | ME361892 | 1.28 | 0.99 | 1.42 | 1.39 | 0.66 | 0.67 | 0.87 | 0.69 |
Fructose | ME361645 | 1.16 | 0.88 | 1.35 | 0.83 | 1.13 | 0.96 | 1.01 | 0.69 |
dihydroxyacetone phosphate (DHAP) | ME361890 | 1.17 | 1.07 | 1.21 | 1.06 | 0.72 | 1.04 | 1.13 | 0.57 |
Fructose-6-phosphate + 1 | ME361650 | 0.94 | 1.27 | 1.43 | 0.99 | 0.90 | 0.94 | 1.00 | 0.48 |
G6P + 1 | ME361656 | 1.05 | 1.24 | 1.51 | 1.02 | 0.84 | 0.88 | 1.00 | 0.46 |
Fructose-6-phosphate | ME361648 | 1.13 | 1.04 | 1.48 | 0.89 | 1.04 | 0.84 | 1.13 | 0.47 |
G6P | ME361655 | 1.17 | 1.10 | 1.61 | 0.92 | 0.93 | 0.76 | 1.08 | 0.44 |
Myristoyl-carnitine | ME361895 | 1.08 | 0.78 | 1.79 | 0.84 | 0.96 | 0.91 | 0.70 | 0.95 |
Palmitoyl-carnitine | ME361896 | 0.84 | 0.95 | 1.49 | 1.28 | 0.78 | 0.91 | 0.66 | 1.08 |
acetyl-glutamine | ME361748 | 1.08 | 0.80 | 0.89 | 0.83 | 1.70 | 0.84 | 0.85 | 1.15 |
3-hydroxybutyric acid+1 | ME361605 | 1.39 | 0.64 | 1.31 | 0.46 | 1.27 | 1.05 | 1.01 | 0.90 |
Ascorbic Acid | ME361752 | 1.58 | 0.78 | 1.27 | 0.59 | 1.00 | 1.13 | 0.78 | 0.85 |
Glutamine | ME361675 | 1.35 | 0.64 | 1.39 | 0.63 | 1.34 | 0.67 | 1.43 | 0.58 |
Argininosuccinate | ME361829 | 1.16 | 0.78 | 1.14 | 0.84 | 1.13 | 0.83 | 1.51 | 0.63 |
Sedoheptulose-7-phosphate (D) | ME361878 | 1.14 | 0.90 | 1.30 | 0.74 | 1.24 | 0.89 | 1.32 | 0.48 |
2-Hydroxyglutarate | ME361743 | 1.00 | 0.60 | 1.21 | 0.74 | 1.15 | 0.79 | 1.57 | 0.95 |
Aspartate | ME361630 | 1.19 | 0.52 | 1.19 | 0.88 | 1.10 | 0.75 | 1.35 | 1.03 |
Urate | ME361814 | 1.36 | 0.75 | 1.18 | 0.95 | 0.99 | 0.59 | 1.45 | 0.72 |
Homocysteine | ME361779 | 1.36 | 0.61 | 1.57 | 0.88 | 1.08 | 0.49 | 1.29 | 0.72 |
Glutamate | ME361669 | 1.27 | 0.65 | 1.40 | 0.95 | 0.98 | 0.71 | 1.13 | 0.92 |
Pyroglutamate | ME361799 | 1.24 | 0.68 | 1.40 | 0.86 | 1.09 | 0.69 | 1.25 | 0.81 |
Acetyl CoA | ME361609 | 1.07 | 0.81 | 1.03 | 0.69 | 1.02 | 1.39 | 1.31 | 0.68 |
Acetyl CoA+1 | ME361610 | 1.05 | 0.81 | 1.02 | 0.70 | 0.99 | 1.47 | 1.32 | 0.64 |
cis-aconitate | ME361840 | 1.34 | 0.68 | 0.84 | 0.86 | 1.17 | 1.00 | 1.27 | 0.85 |
Citrate | ME361637 | 1.27 | 0.78 | 0.85 | 0.89 | 0.96 | 1.14 | 1.16 | 0.95 |
Trehalose | ME361809 | 1.11 | 0.88 | 0.83 | 0.56 | 1.26 | 1.27 | 1.20 | 0.90 |
Glucose | ME361662 | 1.09 | 0.85 | 0.95 | 0.59 | 1.47 | 1.14 | 1.25 | 0.68 |
Ribose | ME361800 | 1.13 | 0.91 | 1.00 | 0.61 | 1.41 | 1.13 | 1.20 | 0.65 |
Guanosine | ME361776 | 1.06 | 0.77 | 0.84 | 0.82 | 1.46 | 1.07 | 1.21 | 0.79 |
Guanosine + 1 | ME361777 | 1.11 | 0.72 | 0.81 | 0.79 | 1.54 | 1.08 | 1.26 | 0.72 |
Malate | ME361696 | 1.44 | 0.70 | 1.16 | 0.66 | 1.22 | 0.77 | 1.24 | 0.83 |
Uridine | ME361815 | 1.07 | 0.57 | 1.24 | 0.72 | 1.46 | 0.84 | 1.17 | 0.95 |
hypoxanthine | ME361780 | 1.26 | 0.59 | 1.09 | 0.76 | 1.24 | 0.96 | 1.21 | 0.91 |
Ribose phosphate | ME361801 | 1.15 | 0.74 | 1.12 | 0.64 | 1.38 | 0.93 | 1.27 | 0.79 |
Succinic Acid | ME361732 | 1.07 | 0.76 | 1.00 | 0.63 | 1.41 | 0.95 | 1.34 | 0.87 |
Xanthine | ME361816 | 1.11 | 0.66 | 1.02 | 0.64 | 1.33 | 1.00 | 1.30 | 0.96 |
methyl-lysine (N) | ME361784 | 0.84 | 0.73 | 0.93 | 0.75 | 1.03 | 1.53 | 1.02 | 1.17 |
Docosahexaenoic acid | ME361767 | 0.93 | 0.80 | 1.02 | 0.64 | 1.11 | 1.40 | 0.92 | 1.19 |
S-Adenosyl-L-Homocysteine | ME361802 | 0.93 | 0.87 | 0.96 | 0.68 | 1.14 | 1.22 | 0.97 | 1.24 |
Methionine | ME361701 | 0.82 | 0.73 | 0.80 | 0.79 | 1.19 | 1.17 | 1.14 | 1.38 |
Adenosine + 2 | ME361825 | 0.86 | 0.65 | 0.85 | 0.87 | 1.32 | 1.25 | 1.02 | 1.20 |
Adenosine | ME361823 | 0.89 | 0.64 | 0.87 | 0.86 | 1.35 | 1.21 | 1.04 | 1.16 |
Adenosine + 1 | ME361824 | 0.89 | 0.64 | 0.88 | 0.86 | 1.33 | 1.22 | 1.04 | 1.17 |
Arachidonic acid | ME361751 | 0.82 | 0.78 | 0.99 | 0.82 | 1.13 | 1.29 | 1.01 | 1.17 |
acetyl-lysine | ME361749 | 0.83 | 0.81 | 0.94 | 0.94 | 1.10 | 1.21 | 1.07 | 1.11 |
Lysine | ME361695 | 0.91 | 0.85 | 0.97 | 0.90 | 1.05 | 1.12 | 1.11 | 1.10 |
Phenylalanine | ME361795 | 0.92 | 0.86 | 0.93 | 0.92 | 1.05 | 1.14 | 1.08 | 1.11 |
Allantoin | ME361886 | 0.76 | 0.85 | 0.90 | 0.97 | 1.03 | 1.35 | 1.08 | 1.06 |
AMP | ME361623 | 0.85 | 0.83 | 0.89 | 0.83 | 1.00 | 1.29 | 1.03 | 1.27 |
UMP | ME361813 | 0.83 | 0.93 | 0.84 | 0.82 | 1.05 | 1.33 | 0.99 | 1.21 |
Valine | ME361893 | 0.81 | 0.94 | 0.77 | 0.88 | 1.03 | 1.33 | 1.03 | 1.22 |
GMP | ME361774 | 0.85 | 0.88 | 0.85 | 0.79 | 1.03 | 1.35 | 1.09 | 1.17 |
CMP | ME361760 | 0.82 | 0.89 | 0.80 | 0.85 | 1.03 | 1.31 | 1.13 | 1.18 |
IsoLeucine | ME361689 | 0.86 | 0.90 | 0.79 | 0.87 | 1.02 | 1.24 | 1.14 | 1.17 |
Tryptophan | ME361741 | 0.86 | 0.90 | 0.83 | 0.87 | 1.01 | 1.21 | 1.13 | 1.18 |
Serine | ME361728 | 1.03 | 0.90 | 0.74 | 0.92 | 1.05 | 1.01 | 1.22 | 1.12 |
Threonine | ME361740 | 0.92 | 0.80 | 0.83 | 0.99 | 1.01 | 1.07 | 1.17 | 1.22 |
Leucine | ME361694 | 0.90 | 0.82 | 0.84 | 0.84 | 1.09 | 1.15 | 1.18 | 1.18 |
Fructose +1 | ME361646 | 0.96 | 0.77 | 0.81 | 0.73 | 1.26 | 1.11 | 1.22 | 1.15 |
Tyrosine | ME361810 | 0.93 | 0.85 | 0.82 | 0.75 | 1.18 | 1.13 | 1.18 | 1.17 |
Butyric acid | ME361754 | 0.92 | 0.82 | 0.96 | 0.84 | 1.24 | 1.01 | 1.16 | 1.06 |
nicotinamide | ME361786 | 0.95 | 0.90 | 0.88 | 0.83 | 1.20 | 1.14 | 1.06 | 1.06 |
aKG | ME361613 | 1.11 | 0.83 | 0.90 | 0.57 | 1.41 | 1.09 | 0.94 | 1.18 |
Glycerol | ME361891 | 0.85 | 0.89 | 0.88 | 0.67 | 1.47 | 1.19 | 1.12 | 0.96 |
Palmitoleic acid | ME361794 | 0.81 | 0.59 | 1.00 | 0.54 | 1.43 | 1.27 | 1.31 | 1.08 |
Succinyladenosine | ME361805 | 0.87 | 0.76 | 0.89 | 0.71 | 1.30 | 1.36 | 1.08 | 1.04 |
Linoleic acid | ME361782 | 0.92 | 0.71 | 1.01 | 0.56 | 1.48 | 1.26 | 0.98 | 1.11 |
Oleic acid | ME361789 | 0.93 | 0.71 | 1.06 | 0.66 | 1.38 | 1.15 | 1.11 | 1.02 |
Oleic acid + 1 | ME361790 | 0.92 | 0.69 | 1.07 | 0.66 | 1.40 | 1.15 | 1.11 | 1.02 |
Palmitic acid+2 | ME361708 | 0.91 | 0.65 | 0.98 | 0.61 | 1.27 | 1.32 | 1.11 | 1.17 |
Palmitic acid | ME361706 | 0.94 | 0.68 | 1.01 | 0.60 | 1.29 | 1.26 | 1.12 | 1.13 |
Palmitic acid+1 | ME361707 | 0.94 | 0.69 | 1.00 | 0.62 | 1.28 | 1.25 | 1.12 | 1.12 |
betaine | ME361753 | 1.01 | 1.07 | 1.34 | 0.91 | 1.06 | 0.98 | 0.72 | 0.92 |
acetyl-carnitine | ME361745 | 1.01 | 0.95 | 1.15 | 0.90 | 1.01 | 1.19 | 0.90 | 0.88 |
Butyryl-carnitine | ME361755 | 0.95 | 0.92 | 1.30 | 0.97 | 1.01 | 1.01 | 0.91 | 0.93 |
Alanine | ME361619 | 0.98 | 1.14 | 0.90 | 0.91 | 1.14 | 0.98 | 1.12 | 0.85 |
Taurine | ME361737 | 0.84 | 0.99 | 1.07 | 1.03 | 1.08 | 1.10 | 0.91 | 1.00 |
Taurine + 1 | ME361738 | 0.86 | 0.98 | 1.06 | 1.02 | 1.08 | 1.11 | 0.92 | 0.97 |
2-hydroxy isocapric acid | ME361742 | 0.82 | 0.93 | 1.03 | 1.03 | 1.00 | 1.13 | 1.05 | 1.00 |
Beta-hydroxyvaleric Acid | ME361888 | 0.81 | 0.80 | 1.08 | 1.08 | 1.00 | 1.14 | 1.13 | 0.97 |
Dodecanoic acid/Lauric acid | ME361768 | 1.01 | 0.95 | 1.02 | 0.78 | 1.10 | 1.02 | 1.07 | 1.05 |
UDP-GlcNAc | ME361812 | 0.92 | 0.93 | 0.99 | 0.76 | 1.05 | 1.15 | 1.18 | 1.03 |
GABA | ME361772 | 0.98 | 0.99 | 0.93 | 1.06 | 0.91 | 1.06 | 0.98 | 1.09 |
Glycine | ME361686 | 0.94 | 1.00 | 0.99 | 0.90 | 1.01 | 1.09 | 1.07 | 1.00 |
GSH | ME361863 | 1.07 | 0.99 | 1.02 | 0.91 | 0.99 | 1.06 | 1.03 | 0.94 |
GSH +1 | ME361864 | 1.03 | 1.01 | 0.98 | 0.91 | 0.96 | 1.11 | 0.99 | 1.01 |
aminoadipate | ME361887 | 0.86 | 0.94 | 1.24 | 0.80 | 0.68 | 0.90 | 1.32 | 1.23 |
Ornithine | ME361791 | 0.82 | 0.80 | 1.22 | 0.90 | 0.88 | 1.12 | 1.24 | 1.01 |
ornithine +1 | ME361792 | 0.80 | 0.81 | 1.24 | 0.91 | 0.86 | 1.13 | 1.23 | 1.01 |
Cytidine | ME361765 | 0.85 | 0.69 | 1.17 | 0.95 | 0.88 | 1.17 | 1.05 | 1.24 |
Propionyl-carnitine | ME361797 | 0.84 | 0.74 | 1.26 | 0.93 | 0.87 | 1.12 | 0.86 | 1.37 |
Myristic acid | ME361785 | 0.99 | 0.78 | 1.12 | 0.75 | 1.05 | 1.23 | 1.01 | 1.06 |
Stearic acid | ME361804 | 1.16 | 0.64 | 1.20 | 0.68 | 0.99 | 1.16 | 1.09 | 1.08 |
Lactate | ME361690 | 0.68 | 1.12 | 0.69 | 1.02 | 1.17 | 1.35 | 1.11 | 0.88 |
Oxypurinol | ME361793 | 0.64 | 0.92 | 0.62 | 0.81 | 1.40 | 1.41 | 1.29 | 0.94 |
ADP | ME361612 | 0.88 | 1.05 | 0.86 | 0.85 | 0.91 | 1.50 | 1.00 | 0.95 |
UDP | ME361811 | 0.77 | 0.95 | 0.82 | 1.00 | 0.99 | 1.53 | 0.96 | 0.97 |
Glucose +1 | ME361663 | 0.83 | 1.05 | 0.73 | 0.72 | 1.13 | 1.52 | 0.96 | 1.07 |
FAD | ME361771 | 0.92 | 1.04 | 0.81 | 0.79 | 1.06 | 1.37 | 0.95 | 1.06 |
NAD+ | ME361702 | 0.97 | 1.16 | 0.73 | 0.80 | 1.03 | 1.43 | 0.96 | 0.93 |
GSSG | ME361897 | 0.81 | 0.69 | 0.72 | 0.78 | 1.07 | 1.63 | 1.17 | 1.14 |
GSSG +1 | ME361898 | 0.73 | 0.65 | 0.66 | 0.77 | 0.97 | 1.59 | 1.06 | 1.13 |
Creatinine | ME361889 | 0.64 | 0.81 | 0.64 | 0.92 | 0.97 | 1.66 | 1.07 | 1.29 |
NADP+ | ME361704 | 0.70 | 0.89 | 0.67 | 0.70 | 1.03 | 1.68 | 1.10 | 1.24 |
Adenine | ME361750 | 0.56 | 0.90 | 0.69 | 0.96 | 1.10 | 1.46 | 1.13 | 1.21 |
Phosphocreatine | ME361796 | 0.73 | 0.89 | 0.68 | 1.01 | 0.85 | 1.52 | 1.20 | 1.10 |
Glycerol 3-phosphate | ME361685 | 0.73 | 0.94 | 0.57 | 1.10 | 0.80 | 1.30 | 1.24 | 1.32 |
Serine+1 | ME361729 | 0.95 | 0.99 | 0.54 | 0.93 | 0.98 | 1.13 | 1.18 | 1.30 |
nicotinamide N-oxide | ME361787 | 0.72 | 1.21 | 0.66 | 0.84 | 0.78 | 1.52 | 0.98 | 1.29 |
PEP | ME361714 | 0.62 | 1.21 | 0.77 | 0.93 | 0.72 | 1.56 | 0.95 | 1.21 |
Proline | ME361718 | 0.68 | 1.13 | 0.74 | 1.20 | 0.83 | 1.24 | 0.88 | 1.28 |
Asparagine | ME361625 | 0.67 | 1.17 | 0.73 | 1.23 | 0.73 | 1.30 | 0.84 | 1.31 |
Proline +1 | ME361719 | 0.65 | 1.17 | 0.70 | 1.21 | 0.80 | 1.28 | 0.85 | 1.32 |
carnitine | ME361756 | 0.82 | 1.17 | 0.81 | 1.02 | 0.89 | 1.45 | 0.73 | 1.11 |
Glutamine +1 | ME361676 | 0.83 | 1.15 | 0.85 | 1.03 | 0.82 | 1.24 | 0.88 | 1.19 |
Glycine+1 | ME361687 | 0.83 | 1.09 | 0.89 | 0.94 | 0.93 | 1.20 | 0.99 | 1.11 |
cAMP | ME361636 | 0.61 | 0.61 | 1.22 | 1.07 | 0.74 | 1.07 | 1.52 | 1.15 |
Ethanolamine phosphate | ME361770 | 0.77 | 0.67 | 1.02 | 1.57 | 0.74 | 0.92 | 1.05 | 1.26 |
Citrulline | ME361847 | 0.95 | 0.96 | 1.04 | 1.03 | 1.02 | 0.85 | 1.37 | 0.78 |
beta Alanine | ME361894 | 0.88 | 0.86 | 1.15 | 1.22 | 0.86 | 0.88 | 1.18 | 0.96 |
Creatine | ME361761 | 0.79 | 0.92 | 0.84 | 1.25 | 0.89 | 1.04 | 1.16 | 1.10 |
SuccinylCys | ME361806 | 0.44 | 0.44 | 0.67 | 0.99 | 1.20 | 1.33 | 1.24 | 1.54 |
5-Oxoproline (pyroglutamic Acid) | ME361817 | 0.62 | 0.64 | 0.64 | 0.54 | 1.74 | 1.14 | 1.76 | 0.98 |
Pyridoxal | ME361798 | 0.42 | 0.31 | 0.56 | 0.62 | 1.74 | 1.55 | 1.58 | 1.23 |
Fructose +2 | ME361647 | 0.67 | 0.55 | 0.65 | 0.35 | 1.51 | 0.81 | 1.25 | 1.40 |
gama-Glutamylcysteine | ME361854 | 0.98 | 0.63 | 0.81 | 0.57 | 1.21 | 1.06 | 1.46 | 1.30 |
Decanoic acid | ME361766 | 1.10 | 0.47 | 0.98 | 0.38 | 1.52 | 1.32 | 1.10 | 1.16 |
Octanoic acid | ME361788 | 1.06 | 0.45 | 0.99 | 0.43 | 1.42 | 1.50 | 0.99 | 1.18 |
Hexanoic acid | ME361778 | 0.73 | 0.69 | 0.73 | 0.58 | 1.40 | 1.31 | 1.28 | 1.28 |
Pyruvate | ME361724 | 0.64 | 0.74 | 0.53 | 0.53 | 1.78 | 1.40 | 1.23 | 1.19 |
Eicosapentaenoic acid | ME361769 | 0.70 | 0.70 | 0.71 | 0.43 | 1.75 | 1.31 | 1.28 | 1.18 |
Linolenic acid | ME361783 | 0.74 | 0.62 | 0.85 | 0.41 | 1.67 | 1.39 | 1.16 | 1.20 |
CTP | ME361762 | NA | 0.85 | 1.18 | 1.05 | NA | 0.97 | 0.98 | NA |
Glyceraldehyde 3-phosphate +1 | ME361682 | NA | 1.02 | 0.81 | 1.56 | 0.76 | 1.02 | 1.18 | NA |
GSH +8 | ME361872 | 0.71 | NA | 0.84 | 1.43 | 0.69 | NA | 0.74 | NA |
Thymidine | ME361808 | 0.57 | 0.47 | 1.21 | 2.04 | 0.42 | 0.42 | 1.33 | 0.99 |
GSSG +8 | ME361905 | 0.58 | 0.64 | 0.58 | 2.24 | 0.49 | 0.57 | 0.68 | 0.87 |
SuccinylGSH | ME361807 | 0.46 | 1.19 | 0.48 | 2.40 | 0.64 | 0.78 | 0.73 | 0.87 |
gama-Glutamylcysteine +1 | ME361855 | 0.48 | 0.60 | 0.30 | 0.44 | 0.74 | 1.49 | 0.99 | 2.74 |
GSSG +2 | ME361899 | 0.03 | 0.90 | 0.04 | 0.87 | 0.04 | 3.31 | 0.05 | 2.56 |
GSSG +3 | ME361900 | 0.03 | 0.66 | 0.02 | 0.59 | 0.02 | 2.53 | 0.03 | 2.07 |
Pyruvate+1 | ME361725 | 0.19 | 0.90 | 0.11 | 0.45 | 0.75 | 2.57 | 0.42 | 2.42 |
Pyruvate+2 | ME361726 | 0.08 | 0.54 | 0.07 | 0.21 | 0.14 | 1.94 | 0.05 | 1.93 |
Glucose +6 | ME361668 | NA | 0.54 | NA | 0.21 | NA | 1.51 | NA | 1.73 |
GSSG +4 | ME361901 | NA | 0.20 | 0.02 | 0.21 | NA | 1.82 | NA | 1.62 |
GSSG +5 | ME361902 | NA | 0.12 | NA | 0.14 | NA | 1.71 | NA | 1.57 |
Adenosine + 4 | ME361827 | NA | 0.18 | NA | 0.18 | NA | 0.51 | NA | 1.55 |
gama-Glutamylcysteine +4 | ME361858 | NA | NA | 0.29 | 0.41 | NA | 0.38 | NA | 2.26 |
gama-Glutamylcysteine +2 | ME361856 | NA | 0.40 | NA | 0.23 | NA | 1.06 | NA | 2.10 |
gama-Glutamylcysteine +3 | ME361857 | NA | 0.25 | NA | 0.19 | NA | 0.76 | NA | 2.22 |
Palmitic acid+4 | ME361710 | NA | 0.48 | NA | 0.22 | NA | 2.66 | NA | 0.45 |
Glycine+2 | ME361688 | 0.60 | 0.95 | NA | NA | NA | 1.71 | NA | 0.99 |
aKG +4 | ME361617 | NA | 0.67 | NA | 0.18 | NA | 2.06 | NA | 0.71 |
citrate +5 | ME361642 | NA | 0.88 | NA | 0.39 | NA | 1.88 | NA | 0.78 |
citrulline +3 | ME361850 | NA | 0.99 | NA | 1.54 | NA | 0.39 | NA | 0.90 |
citrulline +4 | ME361851 | NA | 0.66 | NA | 1.48 | NA | 0.50 | NA | 0.60 |
Argininosuccinate +5 | ME361835 | NA | 0.89 | 1.08 | 0.83 | NA | 1.23 | NA | 1.05 |
Sedoheptulose-7-phosphate (D) + 3 | ME361881 | NA | 1.18 | NA | 0.82 | 0.06 | 1.36 | NA | 0.56 |
3-hydroxybutyric acid+3 | ME361607 | NA | 1.20 | NA | 0.84 | NA | 1.17 | NA | 0.67 |
Glutamine +5 | ME361680 | 0.00 | 1.18 | 0.00 | 0.94 | NA | 1.18 | NA | 0.84 |
Asparagine+2 | ME361627 | NA | 1.13 | NA | 0.95 | NA | 1.13 | NA | 0.79 |
Glutamine +4 | ME361679 | NA | 1.08 | NA | 0.96 | NA | 1.11 | NA | 0.84 |
Glutamate +3 | ME361672 | NA | 0.93 | NA | 0.84 | NA | 0.90 | NA | 1.32 |
Proline +5 | ME361723 | NA | 1.05 | NA | 0.87 | NA | 0.89 | NA | 1.19 |
citrulline +5 | ME361852 | NA | 0.97 | NA | 1.07 | NA | 1.02 | NA | 0.93 |
Glutamate +4 | ME361673 | NA | 0.97 | NA | 1.04 | NA | 0.96 | NA | 1.03 |
Glutamate +5 | ME361674 | NA | 1.03 | NA | 0.99 | NA | 0.97 | NA | 1.01 |
Alanine+3 | ME361622 | NA | 1.11 | NA | 0.94 | NA | 0.96 | NA | 0.99 |
Proline +2 | ME361720 | NA | 1.11 | NA | 1.04 | NA | 0.82 | NA | 1.03 |
Proline +3 | ME361721 | NA | 1.10 | NA | 0.93 | NA | 0.86 | NA | 1.11 |
Proline +4 | ME361722 | NA | 1.09 | NA | 0.95 | NA | 0.88 | NA | 1.07 |
Succinic Acid + 4 | ME361736 | NA | 1.07 | NA | 0.68 | NA | 1.22 | NA | 1.04 |
cis-aconitate + 2 | ME361842 | NA | 0.94 | NA | 0.75 | NA | 1.15 | NA | 1.10 |
Succinic Acid + 2 | ME361734 | NA | 0.95 | NA | 0.72 | NA | 1.19 | NA | 1.14 |
cis-aconitate + 3 | ME361843 | NA | 1.03 | NA | 0.59 | NA | 1.10 | NA | 1.21 |
Succinic Acid + 3 | ME361735 | NA | 1.00 | NA | 0.64 | NA | 1.19 | NA | 1.17 |
Glutamine +2 | ME361677 | NA | 1.01 | NA | 0.90 | NA | 1.06 | NA | 1.03 |
glutamine +3 | ME361678 | NA | 1.02 | NA | 0.84 | NA | 1.10 | NA | 1.03 |
malate +4 | ME361700 | NA | 1.17 | NA | 0.74 | NA | 0.99 | NA | 1.09 |
malate +2 | ME361698 | NA | 1.02 | NA | 0.73 | NA | 1.04 | NA | 1.20 |
Alanine+2 | ME361621 | NA | 1.08 | NA | 0.77 | NA | 1.04 | NA | 1.10 |
malate +3 | ME361699 | NA | 1.08 | NA | 0.73 | NA | 1.02 | NA | 1.16 |
citrate +6 | ME361643 | NA | 0.74 | NA | 0.82 | NA | 1.16 | NA | 0.98 |
Lactate+3 | ME361693 | NA | 0.94 | NA | 0.91 | NA | 1.28 | NA | 0.87 |
3-hydroxybutyric acid+2 | ME361606 | NA | 0.89 | NA | 0.82 | NA | 1.30 | NA | 0.99 |
Lactate+2 | ME361692 | NA | 0.94 | NA | 0.80 | NA | 1.26 | NA | 0.99 |
5-Oxoproline (pyroglutamic Acid) +2 | ME361819 | 0.29 | 0.81 | 0.31 | 0.62 | NA | 1.48 | NA | 1.37 |
cis-aconitate + 1 | ME361841 | 0.25 | 1.06 | 0.17 | 0.98 | 0.20 | 1.48 | 0.18 | 1.29 |
3-hydroxybutyric acid+4 | ME361608 | NA | 1.31 | NA | 0.32 | NA | 1.34 | NA | 1.03 |
5-Oxoproline (pyroglutamic Acid) +4 | ME361821 | NA | 1.04 | 0.04 | 0.33 | NA | 1.70 | 0.05 | 1.04 |
citrate +3 | ME361640 | 0.00 | 0.96 | 0.00 | 0.66 | 0.00 | 1.58 | 0.01 | 1.20 |
citrate +4 | ME361641 | NA | 0.86 | NA | 0.50 | NA | 1.63 | NA | 1.01 |
Pyruvate+3 | ME361727 | NA | 0.79 | NA | 0.48 | NA | 1.52 | NA | 1.21 |
PEP+1 | ME361715 | NA | 0.40 | NA | 0.46 | NA | 1.00 | NA | 1.33 |
Aspartate + 4 | ME361634 | NA | 0.87 | NA | 0.73 | NA | 0.97 | NA | 1.43 |
Aspartate + 2 | ME361632 | NA | 0.78 | NA | 0.75 | NA | 0.98 | NA | 1.49 |
Aspartate + 3 | ME361633 | NA | 0.81 | NA | 0.70 | NA | 1.00 | NA | 1.49 |
Glucose +3 | ME361665 | NA | 0.95 | 0.00 | 0.64 | 0.00 | 1.67 | 0.00 | 1.47 |
GSH +2 | ME361866 | 0.00 | 0.90 | 0.00 | 0.70 | 0.00 | 1.45 | 0.00 | 1.66 |
aKG +2 | ME361615 | 0.01 | 0.98 | 0.02 | 0.47 | NA | 1.29 | 0.01 | 1.46 |
aKG +3 | ME361616 | NA | 0.94 | NA | 0.26 | NA | 1.23 | NA | 1.52 |
GSH +3 | ME361867 | 0.00 | 0.79 | 0.00 | 0.52 | NA | 1.31 | NA | 1.51 |
GSH +4 | ME361868 | NA | 0.72 | NA | 0.59 | NA | 1.21 | NA | 1.43 |
GSH +5 | ME361869 | NA | 0.75 | NA | 0.52 | NA | 1.20 | NA | 1.46 |
5-Oxoproline (pyroglutamic Acid) +3 | ME361820 | NA | 0.68 | NA | 0.39 | NA | 1.53 | NA | 1.40 |
Glucose +4 | ME361666 | NA | 0.75 | NA | 0.47 | NA | 1.39 | NA | 1.40 |
Glucose +5 | ME361667 | NA | 0.70 | NA | 0.40 | NA | 1.43 | NA | 1.48 |
Argininosuccinate +4 | ME361834 | NA | 1.90 | NA | 0.87 | NA | 0.45 | NA | 0.73 |
Asparagine+3 | ME361628 | NA | 1.50 | NA | 0.92 | NA | 0.42 | 0.46 | 0.72 |
Argininosuccinate +2 | ME361832 | 0.04 | 1.76 | 0.03 | 1.43 | 0.04 | 1.19 | 0.06 | 1.03 |
Argininosuccinate +3 | ME361833 | NA | 1.42 | NA | 1.04 | NA | 0.81 | 0.03 | 0.80 |
Fructose-6-phosphate + 3 | ME361649 | NA | 1.56 | NA | 0.85 | NA | 1.13 | NA | 0.34 |
G6P + 3 | ME361658 | NA | 1.41 | 0.05 | 1.02 | NA | 1.19 | 0.04 | 0.47 |
Acetyl CoA+2 | ME361611 | 0.32 | 1.33 | 0.35 | 1.25 | 0.42 | 2.88 | 0.60 | 0.81 |
Fructose-6-phosphate + 2 | ME361651 | 0.43 | 2.11 | 0.92 | 1.73 | 0.36 | 1.16 | 0.43 | 0.53 |
Sedoheptulose-7-phosphate (D) + 2 | ME361880 | 0.19 | 2.09 | 0.40 | 1.40 | 0.27 | 2.17 | 0.44 | 0.94 |
Argininosuccinate +1 | ME361830 | 0.47 | 1.88 | 0.42 | 1.63 | 0.45 | 1.44 | 0.64 | 1.03 |
citrulline +1 | ME361848 | 0.37 | 1.81 | 0.40 | 1.64 | 0.39 | 1.49 | 0.53 | 1.33 |
Asparagine+1 | ME361626 | 0.19 | 1.89 | 0.19 | 1.75 | 0.20 | 1.94 | 0.24 | 1.53 |
citrulline +2 | ME361849 | 0.14 | 1.93 | 0.19 | 2.08 | 0.21 | 1.48 | 0.35 | 1.56 |
Glutamate +2 | ME361671 | 0.00 | 1.70 | 0.01 | 1.88 | 0.01 | 1.78 | 0.01 | 2.54 |
citrate +2 | ME361639 | 0.02 | 1.61 | 0.02 | 1.43 | 0.02 | 2.45 | 0.03 | 1.90 |
aKG +1 | ME361614 | 0.43 | 1.46 | 0.25 | 0.57 | 0.59 | 1.91 | 0.28 | 2.44 |
Aspartate + 1 | ME361631 | 0.40 | 1.21 | 0.40 | 1.21 | 0.37 | 1.59 | 0.45 | 2.32 |
Glucose +2 | ME361664 | 0.25 | 1.44 | 0.24 | 0.98 | 0.35 | 2.37 | 0.32 | 2.00 |
citrate +1 | ME361638 | 0.40 | 1.50 | 0.24 | 1.28 | 0.30 | 2.14 | 0.38 | 1.72 |
malate +1 | ME361697 | 0.35 | 1.69 | 0.28 | 1.26 | 0.29 | 1.77 | 0.30 | 2.01 |
Succinic Acid + 1 | ME361733 | 0.28 | 1.58 | 0.27 | 1.17 | 0.38 | 1.99 | 0.36 | 1.92 |
Cysteine | ME361644 | 2.92 | 1.15 | 2.41 | 0.64 | 0.16 | 0.08 | 0.22 | 0.18 |
Cystine | ME361764 | 1.63 | 0.87 | 0.98 | 0.49 | NA | NA | 0.24 | 0.29 |
Serine+2 | ME361730 | 1.01 | 1.24 | 1.01 | NA | NA | NA | NA | 0.74 |
Factors:
F1 | Age:Old | Genotype:SIRT6-tg | Treatment:N/A |
F2 | Age:Old | Genotype:SIRT6-tg | Treatment:[U-13C]Lactate |
F3 | Age:Old | Genotype:Wild-type | Treatment:N/A |
F4 | Age:Old | Genotype:Wild-type | Treatment:[U-13C]Lactate |
F5 | Age:Young | Genotype:SIRT6-tg | Treatment:N/A |
F6 | Age:Young | Genotype:SIRT6-tg | Treatment:[U-13C]Lactate |
F7 | Age:Young | Genotype:Wild-type | Treatment:N/A |
F8 | Age:Young | Genotype:Wild-type | Treatment:[U-13C]Lactate |