Clustering data with hclust algorithm for (Study ST002035)
(Analysis AN003309)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Phosphocreatine | ME471837 | 0.04 | 0.13 | 0.23 | 0.48 | 0.07 | 4.87 | 0.02 | 0.08 | 2.89 | 0.22 | 0.52 | 3.29 |
| gamma-L-Glutamylputrescine | ME471826 | 2.51 | 1.52 | 0.94 | 1.34 | 2.54 | 0.47 | 0.63 | 0.32 | 0.19 | 0.27 | 0.40 | 0.16 |
| Adenosine | ME471802 | 0.52 | 2.89 | 0.50 | 1.36 | 0.74 | 0.50 | 0.54 | 1.65 | 0.89 | 1.11 | 0.51 | 0.72 |
| ADP-D-ribose | ME471818 | 1.78 | 1.69 | 0.72 | 0.96 | 1.45 | 0.23 | 1.67 | 1.25 | 0.36 | 0.64 | 0.68 | 0.29 |
| Pantetheine 4--phosphate | ME471842 | 1.55 | 1.20 | 0.68 | 0.75 | 1.83 | 0.30 | 2.03 | 1.23 | 0.43 | 0.61 | 0.75 | 0.41 |
| AMP | ME471801 | 1.08 | 1.57 | 1.08 | 1.41 | 0.91 | 0.49 | 0.81 | 1.30 | 0.59 | 1.21 | 0.93 | 0.41 |
| GMP | ME471804 | 1.12 | 1.37 | 1.15 | 1.60 | 0.91 | 0.51 | 1.21 | 1.01 | 0.47 | 0.77 | 1.24 | 0.41 |
| UMP | ME471810 | 1.27 | 1.20 | 1.16 | 1.67 | 0.68 | 0.41 | 1.10 | 1.34 | 0.39 | 1.18 | 1.08 | 0.26 |
| 6-Hydroxykynurenic acid | ME471848 | 1.69 | 1.01 | 1.10 | 1.02 | 1.05 | 1.03 | 0.74 | 0.90 | 0.42 | 0.65 | 1.75 | 0.32 |
| Putrescine | ME471833 | 1.16 | 1.21 | 0.91 | 1.75 | 1.39 | 0.87 | 0.86 | 0.94 | 0.72 | 0.61 | 1.03 | 0.38 |
| Sphingosine | ME471855 | 1.46 | 1.07 | 1.06 | 1.80 | 1.12 | 0.69 | 0.84 | 0.75 | 0.60 | 0.69 | 1.31 | 0.43 |
| Carnosine | ME471836 | 1.84 | 1.23 | 1.08 | 1.38 | 1.61 | 0.91 | 0.67 | 0.77 | 0.53 | 0.58 | 0.69 | 0.53 |
| Indole-3-acetate | ME471846 | 1.42 | 1.04 | 1.09 | 1.24 | 1.65 | 0.97 | 0.78 | 0.70 | 0.71 | 0.67 | 1.05 | 0.53 |
| Indole-3-acetaldehyde | ME471845 | 0.69 | 0.48 | 0.84 | 0.90 | 0.37 | 0.80 | 1.53 | 0.98 | 1.11 | 1.62 | 1.67 | 1.04 |
| Tetradecenoyl Carnitine (acyl-C14:1) | ME471873 | 0.91 | 0.74 | 0.78 | 0.40 | 1.26 | 0.72 | 0.46 | 2.58 | 1.00 | 0.79 | 1.10 | 1.32 |
| acyl-C18:2 (Linoleoyl-CoA) | ME471878 | 0.70 | 0.46 | 0.92 | 0.17 | 0.72 | 1.53 | 0.41 | 1.40 | 1.92 | 0.88 | 1.57 | 1.64 |
| O-Decenoyl-L-carnitine (acyl-C10:1) | ME471869 | 0.74 | 0.65 | 1.24 | 0.57 | 0.97 | 0.65 | 0.53 | 1.82 | 1.19 | 0.99 | 1.48 | 1.26 |
| O-dodecanoyl-carnitine (acyl-C12) | ME471870 | 0.94 | 0.57 | 0.69 | 0.44 | 1.07 | 0.95 | 0.52 | 2.09 | 1.11 | 0.80 | 1.40 | 1.56 |
| O-dodecenoyl-carnitine (acyl-C12:1) | ME471871 | 0.85 | 0.63 | 0.84 | 0.52 | 0.91 | 0.94 | 0.47 | 2.03 | 1.25 | 0.89 | 1.27 | 1.57 |
| Hexadecenoyl-carnitine (acyl-C16:1) | ME471875 | 0.95 | 0.58 | 0.85 | 0.33 | 1.21 | 1.12 | 0.45 | 1.63 | 1.25 | 0.81 | 1.34 | 1.65 |
| O-tetradecanoyl-L-carnitine (acyl-C14) | ME471872 | 0.99 | 0.54 | 0.80 | 0.38 | 1.03 | 1.08 | 0.73 | 1.53 | 1.19 | 0.75 | 1.48 | 1.66 |
| acyl-C18:2-OH | ME471879 | 1.22 | 0.73 | 0.69 | 0.32 | 1.13 | 0.96 | 0.86 | 1.63 | 1.44 | 0.69 | 1.28 | 1.17 |
| O-octadecenoyl-L-carnitine (acyl-C18:1) | ME471877 | 0.97 | 0.72 | 0.75 | 0.26 | 1.13 | 1.20 | 0.51 | 1.33 | 1.44 | 0.76 | 1.73 | 1.35 |
| L-Palmitoylcarnitine (acyl-C16) | ME471874 | 0.81 | 0.53 | 0.71 | 0.31 | 1.39 | 1.14 | 0.67 | 1.43 | 1.26 | 0.67 | 1.74 | 1.51 |
| Octadecanoyl-L-carnitine (acyl-C18) | ME471876 | 0.93 | 0.54 | 0.73 | 0.48 | 1.43 | 1.18 | 0.60 | 1.28 | 1.25 | 0.83 | 1.61 | 1.23 |
| NAD+ | ME471820 | 0.51 | 0.54 | 1.13 | 0.90 | 0.73 | 1.44 | 0.44 | 0.99 | 1.50 | 1.60 | 1.00 | 1.39 |
| Ectoine | ME471853 | 0.83 | 0.49 | 0.86 | 0.41 | 1.52 | 1.46 | 1.23 | 0.98 | 0.91 | 0.62 | 1.32 | 1.44 |
| NADH | ME471821 | 0.89 | 0.31 | 0.72 | 0.36 | 1.59 | 1.46 | 0.99 | 0.95 | 1.24 | 0.72 | 1.59 | 1.29 |
| Indoxyl | ME471847 | 0.92 | 0.57 | 0.78 | 0.84 | 1.25 | 1.04 | 1.57 | 1.29 | 0.77 | 0.85 | 1.36 | 0.64 |
| Allantoate | ME471814 | 0.89 | 0.67 | 1.03 | 0.89 | 0.99 | 1.05 | 1.51 | 0.82 | 0.61 | 0.84 | 1.67 | 0.95 |
| Ornithine | ME471830 | 0.88 | 0.71 | 0.95 | 0.78 | 1.53 | 1.07 | 1.32 | 0.84 | 0.70 | 0.78 | 1.50 | 0.84 |
| Xanthine | ME471813 | 1.00 | 0.64 | 0.90 | 0.64 | 1.56 | 1.16 | 1.10 | 0.85 | 0.85 | 0.64 | 1.55 | 1.11 |
| Argininosuccinate | ME471832 | 0.78 | 0.99 | 0.90 | 0.40 | 1.18 | 1.18 | 1.04 | 0.66 | 1.24 | 1.07 | 0.98 | 1.77 |
| Nicotinamide | ME471817 | 1.29 | 1.32 | 0.77 | 0.86 | 1.44 | 0.70 | 1.22 | 1.17 | 0.80 | 0.78 | 0.82 | 0.75 |
| propionyl-carnitine (acyl-C3) | ME471860 | 1.28 | 1.35 | 1.03 | 1.35 | 0.78 | 0.68 | 1.00 | 1.15 | 0.82 | 0.98 | 0.78 | 0.70 |
| acyl-C4-OH | ME471862 | 0.90 | 1.58 | 0.98 | 1.36 | 0.74 | 0.69 | 0.98 | 1.02 | 0.71 | 1.02 | 0.98 | 0.96 |
| acyl-C5:1 | ME471864 | 0.93 | 1.34 | 0.99 | 1.27 | 0.81 | 0.77 | 0.86 | 1.02 | 1.00 | 1.19 | 0.83 | 0.98 |
| butanoyl-l-carnitine (acyl-C4) | ME471861 | 0.94 | 0.91 | 1.12 | 1.33 | 0.66 | 0.95 | 0.71 | 0.98 | 1.08 | 1.27 | 0.97 | 1.12 |
| L-aspartate | ME471786 | 0.81 | 0.68 | 1.03 | 1.45 | 0.63 | 0.75 | 1.04 | 0.87 | 1.16 | 1.34 | 1.08 | 1.25 |
| Spermidine | ME471834 | 0.83 | 0.90 | 0.93 | 1.59 | 1.16 | 0.75 | 0.95 | 0.88 | 1.03 | 0.79 | 1.20 | 0.98 |
| 6-Phospho-D-gluconate | ME471822 | 0.98 | 0.84 | 1.08 | 1.26 | 0.93 | 0.94 | 0.94 | 1.12 | 0.82 | 0.93 | 1.33 | 0.74 |
| acetyl-carnitine (acyl-C2) | ME471859 | 0.95 | 0.94 | 0.98 | 1.36 | 0.89 | 0.84 | 1.06 | 1.01 | 0.83 | 1.14 | 0.98 | 1.00 |
| Dimethylglycine | ME471827 | 1.34 | 0.75 | 1.04 | 0.88 | 1.20 | 1.30 | 0.91 | 1.04 | 0.64 | 0.61 | 1.14 | 1.10 |
| N-Acetylornithine | ME471839 | 1.28 | 0.97 | 1.03 | 1.06 | 1.40 | 1.45 | 0.75 | 0.71 | 0.75 | 0.85 | 0.73 | 0.97 |
| Anthranilate | ME471849 | 0.86 | 0.62 | 1.00 | 0.70 | 0.91 | 1.42 | 1.01 | 1.01 | 1.16 | 0.86 | 1.15 | 1.42 |
| S-Adenosyl-L-homocysteine | ME471828 | 1.19 | 0.82 | 0.84 | 0.62 | 1.29 | 0.82 | 1.18 | 1.00 | 0.98 | 0.71 | 1.36 | 1.24 |
| g-Oxalo-crotonate | ME471851 | 0.99 | 0.79 | 0.87 | 0.66 | 0.91 | 0.99 | 1.41 | 0.88 | 0.97 | 0.79 | 1.40 | 1.42 |
| L-methionine | ME471793 | 1.04 | 0.66 | 0.96 | 0.74 | 0.95 | 0.99 | 1.20 | 1.00 | 1.04 | 0.83 | 1.35 | 1.30 |
| Adenine | ME471803 | 1.00 | 1.26 | 0.73 | 0.97 | 1.11 | 0.73 | 0.77 | 1.36 | 1.16 | 1.01 | 0.90 | 1.04 |
| L-tyrosine | ME471799 | 1.33 | 0.72 | 0.82 | 1.10 | 1.25 | 0.87 | 1.09 | 0.89 | 0.97 | 0.88 | 1.00 | 1.09 |
| L-leucine/isoleucine | ME471791 | 1.14 | 0.91 | 0.98 | 0.98 | 1.24 | 1.05 | 0.93 | 0.88 | 0.99 | 0.85 | 1.05 | 1.01 |
| L-phenylalanine | ME471794 | 1.30 | 0.91 | 0.97 | 1.00 | 1.42 | 0.97 | 0.88 | 0.89 | 0.85 | 0.80 | 1.06 | 0.91 |
| Indole | ME471844 | 1.07 | 0.91 | 0.93 | 0.95 | 1.47 | 0.84 | 1.05 | 1.00 | 0.92 | 0.79 | 1.16 | 0.86 |
| L-lysine | ME471792 | 0.93 | 0.92 | 0.86 | 0.90 | 1.36 | 0.96 | 1.05 | 1.05 | 0.93 | 1.05 | 1.08 | 0.89 |
| Hypotaurine | ME471843 | 1.43 | 0.99 | 0.88 | 1.16 | 1.18 | 0.92 | 0.92 | 0.97 | 0.88 | 0.80 | 1.08 | 0.73 |
| Homocarnosine | ME471835 | 1.27 | 1.04 | 1.05 | 1.02 | 1.49 | 0.93 | 0.78 | 1.02 | 0.82 | 0.90 | 0.85 | 0.72 |
| Cys-Gly | ME471825 | 1.08 | 1.11 | 1.14 | 1.30 | 1.22 | 1.12 | 0.81 | 0.76 | 0.96 | 0.89 | 0.82 | 0.72 |
| Glutathione | ME471823 | 1.14 | 1.05 | 1.06 | 1.17 | 1.28 | 1.11 | 0.81 | 0.87 | 0.80 | 0.89 | 0.98 | 0.76 |
| Cytidine | ME471807 | 1.13 | 1.15 | 0.93 | 0.71 | 1.41 | 1.08 | 0.69 | 0.85 | 1.01 | 1.06 | 0.89 | 1.11 |
| Flavin mononucleotide | ME471819 | 0.87 | 0.77 | 1.01 | 0.64 | 1.38 | 1.08 | 0.90 | 1.07 | 1.10 | 0.87 | 1.27 | 1.08 |
| Hypoxanthine | ME471812 | 0.97 | 0.75 | 0.97 | 0.64 | 1.25 | 1.07 | 1.02 | 1.04 | 1.16 | 0.85 | 1.11 | 1.26 |
| L-proline | ME471795 | 1.11 | 0.77 | 0.92 | 0.79 | 1.23 | 1.08 | 0.98 | 0.92 | 1.07 | 0.83 | 1.22 | 1.12 |
| L-Adrenaline | ME471852 | 0.97 | 0.83 | 1.00 | 1.03 | 0.83 | 0.80 | 1.04 | 1.13 | 1.16 | 1.15 | 1.09 | 0.99 |
| Guanidinoacetate | ME471840 | 1.07 | 0.63 | 0.80 | 0.91 | 0.93 | 0.90 | 1.14 | 1.21 | 1.08 | 1.01 | 1.30 | 1.04 |
| L-serine | ME471796 | 1.05 | 0.66 | 1.06 | 0.88 | 0.95 | 0.87 | 1.04 | 1.14 | 1.15 | 0.96 | 1.26 | 1.02 |
| Guanine | ME471806 | 0.82 | 1.05 | 0.99 | 0.82 | 1.06 | 0.98 | 1.00 | 1.05 | 1.05 | 0.96 | 1.12 | 1.14 |
| L-threonine | ME471797 | 0.88 | 0.86 | 0.91 | 0.85 | 1.03 | 1.01 | 1.07 | 1.08 | 1.12 | 0.98 | 1.19 | 1.06 |
| Choline | ME471857 | 0.90 | 0.69 | 0.95 | 0.86 | 1.08 | 1.04 | 1.06 | 0.97 | 1.10 | 0.93 | 1.29 | 1.19 |
| L-glutamate | ME471787 | 0.88 | 0.77 | 0.97 | 0.82 | 0.98 | 1.09 | 1.03 | 0.96 | 1.09 | 1.05 | 1.10 | 1.36 |
| glycine | ME471789 | 0.98 | 0.81 | 1.09 | 0.99 | 0.94 | 1.07 | 1.05 | 0.88 | 0.96 | 0.90 | 1.33 | 0.99 |
| L-tryptophan | ME471798 | 1.06 | 0.87 | 0.93 | 0.98 | 1.12 | 0.87 | 1.07 | 1.12 | 0.97 | 0.84 | 1.21 | 0.95 |
| L-valine | ME471800 | 1.03 | 0.78 | 0.93 | 0.97 | 1.15 | 0.96 | 1.05 | 1.04 | 1.01 | 0.87 | 1.21 | 1.00 |
| L-Citrulline | ME471831 | 1.31 | 0.69 | 0.97 | 0.83 | 1.08 | 1.20 | 0.95 | 0.92 | 1.07 | 0.95 | 0.92 | 1.15 |
| L-arginine | ME471784 | 1.06 | 1.08 | 0.82 | 0.94 | 1.15 | 0.87 | 0.91 | 1.10 | 1.10 | 1.00 | 0.99 | 1.01 |
| 5-Hydroxyisourate | ME471815 | 0.94 | 0.87 | 0.91 | 0.98 | 1.12 | 1.03 | 0.86 | 1.12 | 1.10 | 1.03 | 1.06 | 0.99 |
| Creatinine | ME471838 | 1.01 | 0.96 | 0.94 | 0.78 | 1.23 | 1.10 | 0.89 | 1.09 | 1.10 | 0.98 | 0.96 | 0.96 |
| L-Carnitine | ME471858 | 1.09 | 0.88 | 0.94 | 0.85 | 1.09 | 1.04 | 0.83 | 1.08 | 1.18 | 1.14 | 0.89 | 1.05 |
| 5-Oxoproline | ME471824 | 1.08 | 0.90 | 0.90 | 0.91 | 1.16 | 1.06 | 0.83 | 1.03 | 1.14 | 1.09 | 0.93 | 0.99 |
| L-glutamine | ME471788 | 1.11 | 0.92 | 0.89 | 0.93 | 1.17 | 1.07 | 0.84 | 1.07 | 1.12 | 1.07 | 0.92 | 0.90 |
| Picolinic acid | ME471850 | 0.82 | 1.01 | 1.05 | 0.98 | 1.13 | 1.08 | 0.97 | 1.01 | 1.01 | 1.00 | 1.01 | 0.91 |
| S-Adenosyl-L-methionine | ME471829 | 0.85 | 0.98 | 1.00 | 0.95 | 1.22 | 1.04 | 0.94 | 1.03 | 1.04 | 1.07 | 0.96 | 0.91 |
| Thymidine | ME471809 | 0.86 | 0.88 | 0.97 | 0.99 | 1.17 | 1.17 | 0.97 | 0.91 | 1.01 | 0.93 | 1.01 | 1.16 |
| L-alanine | ME471783 | 0.93 | 0.86 | 1.03 | 0.81 | 1.07 | 1.18 | 0.93 | 1.01 | 1.10 | 1.01 | 1.02 | 1.09 |
| L-asparagine | ME471785 | 1.03 | 0.83 | 1.07 | 0.94 | 1.06 | 1.08 | 0.94 | 0.93 | 1.05 | 1.09 | 0.95 | 1.06 |
| 5-6-Dihydrouracil | ME471841 | 0.98 | 1.02 | 0.93 | 0.86 | 1.19 | 1.23 | 0.68 | 1.13 | 1.02 | 0.93 | 0.96 | 1.10 |
| Cytosine | ME471808 | 1.16 | 1.12 | 0.93 | 0.91 | 1.19 | 1.08 | 0.76 | 0.90 | 0.97 | 0.99 | 0.88 | 1.12 |
| N-Methylethanolamine phosphate | ME471854 | 1.09 | 1.12 | 0.96 | 1.00 | 1.05 | 1.11 | 0.85 | 0.90 | 1.07 | 0.94 | 0.90 | 1.04 |
| L-histidine | ME471790 | 1.06 | 0.70 | 0.88 | 0.76 | 1.23 | 1.01 | 0.94 | 1.17 | 1.22 | 1.05 | 1.08 | 0.92 |
| acyl-C5-OH | ME471865 | 0.87 | 0.80 | 0.86 | 0.92 | 1.00 | 0.98 | 1.00 | 1.11 | 1.30 | 1.08 | 1.00 | 1.17 |
| Pyridoxamine 5^-phosphate | ME471816 | 0.90 | 0.84 | 1.03 | 0.72 | 1.24 | 1.09 | 0.95 | 1.02 | 1.25 | 1.09 | 0.88 | 1.06 |
| Guanosine | ME471805 | 0.98 | 0.89 | 1.04 | 0.79 | 0.98 | 1.06 | 0.88 | 1.11 | 1.18 | 1.03 | 0.92 | 1.23 |
| Inosine | ME471811 | 0.97 | 0.76 | 0.97 | 0.66 | 1.17 | 1.00 | 0.88 | 1.13 | 1.29 | 1.04 | 0.95 | 1.29 |
| acyl-C4-DC | ME471863 | 0.97 | 0.90 | 0.87 | 0.90 | 0.86 | 1.36 | 0.68 | 1.30 | 1.03 | 1.40 | 0.72 | 1.03 |
| Acetylcholine | ME471856 | 0.95 | 0.67 | 0.73 | 0.86 | 0.89 | 0.90 | 0.88 | 1.10 | 1.44 | 1.30 | 0.99 | 1.49 |
| acyl-C20:4 | ME471880 | 0.85 | 0.51 | 1.23 | 0.50 | 0.94 | 1.34 | 0.42 | 1.43 | 1.64 | 1.12 | 1.07 | 1.10 |
| octenoyl-l-carnitine (acyl-C8:1) | ME471868 | 0.87 | 0.72 | 1.07 | 0.63 | 1.27 | 0.88 | 0.74 | 1.30 | 1.32 | 0.93 | 1.07 | 1.32 |
| hexanoyl-L-carnitine (acyl-C6) | ME471866 | 0.85 | 0.80 | 0.97 | 0.75 | 0.99 | 1.32 | 0.50 | 1.22 | 1.23 | 1.10 | 1.07 | 1.31 |
| L-octanoylcarnitine (acyl-C8) | ME471867 | 0.81 | 0.75 | 0.92 | 0.69 | 1.00 | 1.10 | 0.46 | 1.62 | 1.07 | 1.17 | 1.13 | 1.35 |
Factors:
| F1 | Treatment:IV iron | Radiation Dose:Gy10 |
| F2 | Treatment:IV iron | Radiation Dose:Gy11 |
| F3 | Treatment:IV iron | Radiation Dose:Gy7 |
| F4 | Treatment:IV iron | Radiation Dose:Gy8 |
| F5 | Treatment:IV iron | Radiation Dose:Gy9 |
| F6 | Treatment:IV iron | Radiation Dose:no irradiated |
| F7 | Treatment:Saline | Radiation Dose:Gy10 |
| F8 | Treatment:Saline | Radiation Dose:Gy11 |
| F9 | Treatment:Saline | Radiation Dose:Gy7 |
| F10 | Treatment:Saline | Radiation Dose:Gy8 |
| F11 | Treatment:Saline | Radiation Dose:Gy9 |
| F12 | Treatment:Saline | Radiation Dose:no irradiated |