Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST002097)

Reversed phase POSITIVE ION MODE (Analysis AN003426)

Metabolite	Structure	F1	F2	F3	F4	F5	F6
Normetanephrine	ME510623	2.51	0.10	1.35	1.76	0.11	0.18
Gamma-Aminobutyric acid	ME510630	0.26	2.49	0.52	1.22	0.65	0.85
S-(5^-Adenosyl)-L-homocysteine	ME510680	1.99	0.43	1.02	0.59	0.90	1.08
Taurohyodeoxycholic acid	ME510695	2.08	0.24	0.65	0.47	1.43	1.14
Taurolithocholic acid	ME510694	1.97	0.35	0.63	0.44	1.42	1.19
Aminoadipic acid	ME510696	0.23	1.03	0.70	0.97	2.19	0.87
5-Methylcytidine	ME510627	0.84	1.00	0.40	0.93	0.79	2.06
Phosphoenolpyruvic acid	ME510693	0.84	0.95	0.46	0.95	0.66	2.15
L-Glutamate	ME510636	0.36	0.97	0.74	0.77	0.97	2.18
Sphinganine	ME510675	0.63	1.00	0.80	0.69	1.07	1.81
Hexanoylcarnitine	ME510670	1.37	0.58	1.97	0.87	0.87	0.33
Uridine 5^-monophosphate	ME510679	1.49	0.83	1.34	0.73	1.42	0.19
Adenylosuccinic acid	ME510669	1.00	0.77	1.14	0.97	1.73	0.38
Acetylcarnitine	ME510673	1.21	0.30	1.04	0.93	1.74	0.80
Palmitoyl-l-carnitine	ME510671	1.11	0.49	0.97	0.82	1.76	0.86
Taurine	ME510676	2.01	0.86	0.68	0.88	0.96	0.61
Thiamine	ME510685	1.89	0.91	0.80	0.97	0.75	0.68
3-Guanidinopropionic acid?	ME510672	1.48	1.19	1.14	1.17	0.63	0.38
N-Acetylglutamine	ME510657	1.42	0.90	1.15	1.12	0.80	0.62
Dephospho-CoA	ME510681	1.60	1.24	1.49	0.78	0.57	0.32
L-Ascorbic acid	ME510643	1.63	1.26	1.20	0.65	0.97	0.29
Betaine	ME510658	0.82	0.92	1.61	0.91	1.11	0.63
3-Phenylpropionylglycine	ME510621	0.94	1.21	1.43	1.15	0.78	0.50
L-Arginine	ME510661	0.78	1.23	1.29	1.14	1.08	0.47
N-Acetyl-L-methionine	ME510626	0.64	1.31	1.28	1.18	0.91	0.68
Isonicotinic acid	ME510648	1.24	0.74	0.92	0.94	1.04	1.12
Nicotinic acid	ME510625	1.24	0.74	0.92	0.94	1.04	1.12
5-aminosalicylic acid	ME510668	1.32	0.69	0.94	0.80	1.10	1.17
Dopamine	ME510647	1.23	0.72	0.96	0.84	1.03	1.22
Uracil	ME510690	1.24	1.08	0.84	0.63	1.27	0.94
2,4-Diaminobutyric acid	ME510615	1.19	0.77	1.01	0.73	1.38	0.93
L-Citrulline	ME510622	0.99	0.91	0.82	0.79	1.39	1.10
2-Deoxyadenosine	ME510650	1.45	0.62	1.17	0.81	1.02	0.93
Adenine	ME510692	1.50	0.55	1.24	0.90	1.17	0.63
Adenosine 5^-monophosphate	ME510674	1.38	0.90	1.09	0.89	1.16	0.58
Adenosine	ME510653	1.30	0.77	1.14	0.91	1.17	0.70
Biotin	ME510652	1.39	0.80	1.12	0.93	1.12	0.65
Inosine	ME510686	1.10	0.93	0.99	0.99	1.07	0.92
Pipecolic acid	ME510699	1.09	0.91	1.14	0.98	1.05	0.82
Pyroglutamic acid	ME510698	1.11	0.91	1.08	0.97	1.05	0.88
Reduced glutathione	ME510649	0.95	1.12	1.26	1.01	0.88	0.77
L-Carnitine hydrochloride	ME510666	1.14	0.97	1.22	1.10	1.07	0.49
2-Aminoimidazole	ME510618	0.90	0.98	1.07	1.12	1.25	0.68
Hippuric acid	ME510639	1.04	1.03	1.13	1.18	0.93	0.69
Spermidine	ME510684	0.97	1.21	1.17	1.05	1.11	0.50
5-Aminolevulinic acid	ME510667	1.01	1.11	1.04	1.15	1.08	0.62
6-Aminocaproic acid	ME510640	0.94	1.14	1.10	1.21	1.04	0.57
Creatine	ME510683	0.91	1.18	1.10	1.15	1.07	0.60
Inosine-5^-monophosphate	ME510655	1.28	0.99	0.91	1.24	1.16	0.43
Guanosine 5^-monophosphate	ME510688	1.17	1.01	0.93	0.93	1.40	0.57
Thymine	ME510663	1.09	0.81	0.96	1.07	1.40	0.68
Putrescine	ME510664	0.70	1.13	1.12	0.79	0.78	1.49
L-Methionine	ME510632	0.52	1.27	0.48	1.32	0.77	1.63
Indole-3-acetic acid	ME510659	0.36	1.27	1.06	1.10	0.93	1.28
Deoxycytidine	ME510646	0.48	1.29	0.71	1.44	0.98	1.10
Cytidine	ME510656	0.18	1.37	0.69	1.30	0.95	1.51
Cytosine	ME510687	0.28	1.44	0.79	1.31	0.93	1.24
Histamine	ME510660	0.29	1.45	0.76	1.31	0.94	1.25
Guanidineacetic acid	ME510628	0.67	1.26	0.97	1.14	0.92	1.04
L-Valine	ME510638	0.66	1.26	0.98	1.15	0.92	1.04
Norvaline	ME510697	0.66	1.26	0.98	1.15	0.92	1.04
Beta-Sitosterol	ME510641	0.91	1.11	0.94	1.04	0.97	1.03
Oxidized glutathione	ME510677	0.90	1.14	1.00	1.07	1.00	0.90
Tryptophan	ME510691	0.75	1.27	1.03	1.10	0.97	0.88
L-Ornithine	ME510701	0.79	1.14	1.06	1.25	0.84	0.92
L-Phenylalanine	ME510635	0.83	1.24	0.99	1.13	0.91	0.90
L-Norleucine	ME510620	0.85	1.16	1.02	1.14	0.92	0.91
Trans-4-Hydroxy-L-proline	ME510642	0.84	1.15	1.03	1.17	0.90	0.92
Isoleucine	ME510616	0.84	1.15	1.03	1.17	0.90	0.92
L-Leucine	ME510633	0.84	1.15	1.03	1.17	0.90	0.92
L-Kynurenine	ME510624	0.72	1.15	0.98	1.18	0.74	1.23
Serotonin	ME510665	0.68	0.97	0.95	1.05	0.96	1.38
his	ME510637	0.77	1.33	0.71	0.94	1.03	1.23
Choline	ME510682	1.10	1.06	0.70	0.95	0.91	1.27
L-Glutamine	ME510700	1.11	1.19	0.83	1.00	0.77	1.10
L-Lysine	ME510662	1.10	1.15	0.83	1.04	0.78	1.10
2^-Deoxycytidine 5^-monophosphate	ME510678	0.82	1.52	0.77	0.85	1.24	0.81
L-Homocysteine	ME510654	0.54	1.70	0.74	0.91	1.13	0.98
Pyridoxal	ME510629	0.61	1.53	0.76	1.46	0.81	0.84
L-Proline	ME510631	0.55	1.69	0.78	1.22	0.89	0.87
L-Homoserine	ME510617	0.54	1.61	0.72	1.15	0.87	1.11
L-Threonine	ME510634	0.57	1.58	0.73	1.18	0.85	1.10
Cytidine monophosphate	ME510651	0.52	1.40	0.90	1.12	1.11	0.94
Acetylcholine	ME510619	0.63	1.50	0.99	1.34	1.00	0.55
2-Deoxyguanosine	ME510645	0.83	1.44	0.93	1.19	0.97	0.64
Alanine	ME510689	0.78	1.46	0.93	1.11	0.99	0.73
Sarcosine	ME510644	0.76	1.51	0.91	1.10	1.01	0.71

Factors:

F1	Treatment:3 times per week with 4 consecutive respectively intraperitoneal injection (10 mL/kg of olive oil)
F2	Treatment:3 times per week with 4 consecutive respectively intraperitoneal injection with 10% CCl4 (10 mL/kg of olive oil)
F3	Treatment:3 times per week with 4 consecutive respectively intraperitoneal injection with 1% CCl4 (10 mL/kg of olive oil)
F4	Treatment:3 times per week with 4 consecutive respectively intraperitoneal injection with 5% CCl4 (10 mL/kg of olive oil)
F5	Treatment:Only intraperitoneally (i.p) injected with 1% CCl4 (10 mL/kg, dissolved in olive oil) at the 12th injection. During the previous 11 times they were treated the same as the healthy controls with an equal volume of olive oil.
F6	Treatment:Only intraperitoneally (i.p) injected with 5% CCl4 (10 mL/kg, dissolved in olive oil) at the 12th injection. During the previous 11 times they were treated the same as the healthy controls with an equal volume of olive oil.

Data matrix