Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST002098)

(Analysis AN003428)

Metabolite	Structure	F1	F2	F3	F4	F5	F6
Hypoxanthine	ME510786	5.43	0.08	0.15	0.10	0.13	0.12
3-Phenylpropionylglycine	ME510735	1.43	1.24	1.57	0.84	0.63	0.29
Biotin	ME510761	0.93	0.88	1.63	1.64	0.57	0.35
L-Kynurenine	ME510738	0.50	1.71	1.20	1.10	0.87	0.62
Indole-3-propionic acid	ME510756	0.61	1.85	1.34	1.31	0.45	0.43
Hippuric acid	ME510752	0.83	1.57	1.32	1.28	0.69	0.31
Pyrogallol	ME510795	0.86	1.43	1.30	1.22	0.80	0.39
Tryptamine	ME510768	0.01	0.83	0.12	0.27	2.81	1.96
Taurohyodeoxycholic acid	ME510798	0.23	0.41	0.55	0.64	2.35	1.82
Taurolithocholic acid	ME510797	0.22	0.59	0.61	0.74	2.04	1.81
Trimethylamine N-oxide	ME510740	1.46	0.52	0.55	1.34	1.46	0.67
Betaine	ME510765	0.35	0.89	0.57	0.55	1.32	2.33
L-Glutamate	ME510750	0.31	1.13	0.56	0.67	1.50	1.83
Uracil	ME510791	1.17	0.44	0.45	0.27	2.07	1.59
Sphinganine	ME510781	0.88	0.55	0.40	0.36	1.96	1.84
Stearic acid	ME510800	0.99	0.29	0.42	0.31	2.07	1.94
Phosphoenolpyruvic acid	ME510796	0.79	0.55	0.81	0.75	1.32	1.79
L-Methionine	ME510746	0.92	0.66	0.66	0.55	1.32	1.88
L-Glutamine	ME510805	0.86	0.46	0.66	0.52	1.40	2.10
L-Histidine	ME510745	0.82	0.52	0.72	0.54	1.39	2.01
L-Lysine	ME510770	0.76	0.53	0.71	0.57	1.34	2.08
Aminoadipic acid	ME510801	0.63	1.03	0.67	0.71	1.66	1.30
Normetanephrine	ME510737	0.55	1.05	0.74	0.70	1.63	1.33
Alanine	ME510790	0.74	0.77	0.77	0.63	1.51	1.58
Sarcosine	ME510757	0.83	0.70	0.77	0.58	1.50	1.63
L-Proline	ME510744	0.83	0.82	0.74	0.74	1.36	1.52
L-Homoserine	ME510731	0.74	0.89	0.75	0.71	1.35	1.57
L-Threonine	ME510748	0.67	0.87	0.76	0.72	1.44	1.54
Putrescine	ME510771	0.70	0.94	0.68	0.73	1.43	1.52
Dopamine	ME510759	1.21	0.76	0.60	0.55	1.38	1.50
Taurine	ME510783	1.28	0.47	0.62	0.50	1.56	1.57
Palmitoyl-l-carnitine	ME510777	0.78	0.51	0.74	0.46	1.76	1.75
2,4-Diaminobutyric acid	ME510729	1.00	0.64	0.73	0.57	1.57	1.48
2-Aminoimidazole	ME510732	0.88	0.82	0.51	0.60	1.73	1.45
Arachidonic acid	ME510799	0.96	0.50	0.56	0.59	1.74	1.64
Spermidine	ME510787	0.92	0.72	0.63	0.52	1.75	1.47
Isonicotinic acid	ME510760	0.99	0.59	0.60	0.54	1.78	1.50
Nicotinic acid	ME510739	0.94	0.64	0.53	0.52	1.84	1.53
Creatinine	ME510774	1.31	0.70	0.72	0.61	1.65	1.00
Deoxycytidine	ME510758	1.15	0.64	0.75	0.74	1.68	1.04
5-aminosalicylic acid	ME510775	1.23	0.72	0.80	0.65	1.43	1.17
Choline	ME510784	1.14	0.73	0.69	0.58	1.59	1.27
L-Cysteic acid	ME510743	1.51	0.66	0.86	0.70	1.13	1.14
Pipecolic acid	ME510804	1.37	0.77	0.76	0.69	1.14	1.26
Pyroglutamic acid	ME510803	1.21	0.77	0.88	0.70	1.08	1.36
5-Methylcytidine	ME510741	1.50	0.80	0.80	0.66	1.33	0.90
Cytidine	ME510763	1.67	0.51	0.82	0.58	1.43	0.99
Hexanoylcarnitine	ME510776	1.28	0.73	1.06	0.99	0.89	1.05
Cytosine	ME510789	1.51	0.74	0.96	1.02	0.84	0.93
Histamine	ME510767	1.51	0.74	0.96	1.02	0.84	0.93
2-Methylhippuric acid	ME510794	1.22	0.96	1.11	0.86	1.13	0.72
Serotonin	ME510772	1.13	1.17	1.01	0.91	1.00	0.78
L-Norleucine	ME510734	0.74	1.07	1.06	1.09	0.97	1.06
L-Phenylalanine	ME510749	0.70	1.19	1.13	1.22	0.88	0.88
L-Leucine	ME510747	0.66	1.20	1.09	1.13	0.88	1.04
Isoleucine	ME510730	0.64	1.21	1.13	1.12	0.86	1.05
Trans-4-Hydroxy-L-proline	ME510755	0.62	1.22	1.13	1.14	0.84	1.05
N-Acetylglutamine	ME510764	1.04	1.12	0.63	0.76	1.10	1.36
Acetylcarnitine	ME510780	1.03	0.55	1.00	0.93	1.15	1.34
Guanidineacetic acid	ME510742	0.84	0.85	0.93	0.84	1.30	1.24
L-Valine	ME510751	0.84	0.86	0.92	0.83	1.28	1.25
Norvaline	ME510802	0.85	0.86	0.92	0.83	1.29	1.25
L-Carnitine hydrochloride	ME510773	0.93	0.79	0.95	1.08	1.12	1.13
6-Aminocaproic acid	ME510753	1.10	0.79	0.84	0.85	1.33	1.08
Creatine	ME510785	1.06	0.84	0.91	0.83	1.27	1.09
3-Guanidinopropionic acid?	ME510778	1.13	0.83	0.87	0.95	1.20	1.02
Acetylcholine	ME510733	1.04	0.86	0.85	1.04	1.17	1.04
Indole-3-acetic acid	ME510766	0.57	1.16	0.96	0.86	1.28	1.17
Daidzein	ME510779	0.78	0.85	1.20	0.87	1.32	0.98
L-Citrulline	ME510736	0.83	1.01	0.89	1.06	1.24	0.98
5-Hydroxy-L-tryptophan	ME510782	0.90	1.09	1.13	0.92	1.04	0.93
Tryptophan	ME510792	0.77	1.16	1.05	0.87	1.23	0.92
Indolepyruvic acid	ME510793	0.43	1.47	0.77	0.79	1.20	1.34
L-Ornithine	ME510806	0.33	1.01	0.77	1.42	1.40	1.06
Beta-Sitosterol	ME510754	2.28	0.12	0.43	0.39	1.60	1.18
L-Arginine	ME510769	3.04	0.65	0.61	0.79	0.49	0.43
Adenosine	ME510762	3.18	0.59	0.94	0.24	0.59	0.46
Inosine	ME510788	3.63	0.52	0.90	0.24	0.40	0.31

Factors:

F1	Treatment:3 times per week with 4 consecutive respectively intraperitoneal injection (10 mL/kg of olive oil)
F2	Treatment:3 times per week with 4 consecutive respectively intraperitoneal injection with 10% CCl4 (10 mL/kg of olive oil)
F3	Treatment:3 times per week with 4 consecutive respectively intraperitoneal injection with 1% CCl4 (10 mL/kg of olive oil)
F4	Treatment:3 times per week with 4 consecutive respectively intraperitoneal injection with 5% CCl4 (10 mL/kg of olive oil)
F5	Treatment:Only intraperitoneally (i.p) injected with 1% CCl4 (10 mL/kg, dissolved in olive oil) at the 12th injection. During the previous 11 times they were treated the same as the healthy controls with an equal volume of olive oil.
F6	Treatment:Only intraperitoneally (i.p) injected with 5% CCl4 (10 mL/kg, dissolved in olive oil) at the 12th injection. During the previous 11 times they were treated the same as the healthy controls with an equal volume of olive oil.

Data matrix