Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST002123)

(Analysis AN003476)

Metabolite	Structure	F1	F2
succinyl-CoA	ME516425	1.39	0.61
Glyceric acid 1,3-biphosphate	ME516602	1.39	0.61
inosine	ME516533	1.39	0.61
oxaloacetate	ME516475	1.37	0.63
Thiamine monophosphate	ME516488	1.38	0.62
L-2-Hydroxyglutaric acid	ME516604	1.38	0.62
sn-glycerol-3-phosphate	ME516512	1.38	0.62
CDP-choline	ME516561	1.40	0.60
dephospho-CoA	ME516419	1.41	0.59
valine	ME516343	1.42	0.58
FAD	ME516498	1.42	0.58
N-carbamoyl-L-aspartate	ME516368	1.42	0.58
D-glucosamine-1-phosphate	ME516433	1.44	0.56
ADP	ME516551	1.43	0.57
UDP-N-acetyl-glucosamine	ME516570	1.43	0.57
UDP-D-glucose	ME516566	1.33	0.67
thiamine	ME516494	1.33	0.67
fructose-6-phosphate	ME516449	1.33	0.67
hypoxanthine	ME516581	1.33	0.67
pyruvate	ME516465	1.31	0.69
cytidine	ME516521	1.32	0.68
arginine	ME516366	1.32	0.68
ATP	ME516563	1.32	0.68
xanthine	ME516582	1.36	0.64
glycine	ME516336	1.36	0.64
phenylpyruvate	ME516413	1.36	0.64
anthranilate	ME516500	1.34	0.66
dAMP	ME516538	1.34	0.66
CDP-ethanolamine	ME516555	1.35	0.65
isocitrate	ME516483	1.35	0.65
S-adenosyl-L-homoCysteine	ME516405	1.26	0.74
UMP	ME516537	1.30	0.70
D-erythrose-4-phosphate	ME516442	1.30	0.70
DL-Pipecolic acid	ME516333	1.30	0.70
N-acetyl-glutamine	ME516373	1.29	0.71
Ng,NG-dimethyl-L-arginine	ME516375	1.28	0.72
N-acetyl-glutamate	ME516374	1.28	0.72
CTP	ME516559	1.28	0.72
AMP	ME516541	1.28	0.72
CMP	ME516536	1.28	0.72
acetoacetate	ME516468	1.71	0.29
shikimate	ME516480	1.76	0.24
octulose-1,8-bisphosphate (OBP)	ME516460	1.74	0.26
ADP-D-glucose	ME516568	1.74	0.26
N-acetyl-glucosamine-1-phosphate	ME516453	1.74	0.26
hexose-phosphate	ME516446	1.87	0.13
ribose-phosphate	ME516444	1.85	0.15
2-Hydroxy-2-methylbutanedioic acid	ME516479	1.82	0.18
Sedoheptulose 1,7-bisphosphate (SBP)	ME516458	1.79	0.21
propionyl-CoA	ME516422	1.48	0.52
malate	ME516477	1.48	0.52
Methionine sulfoxide	ME516362	1.48	0.52
D-Glyceraldehyde 3-phosphate	ME516436	1.45	0.55
a-ketoglutarate	ME516478	1.47	0.53
citrate	ME516484	1.46	0.54
5-methoxytryptophan	ME516378	1.50	0.50
dihydroxy-acetone-phosphate	ME516435	1.51	0.49
N-Acetylornithine	ME516365	1.51	0.49
IMP	ME516542	1.55	0.45
homocysteine	ME516353	1.54	0.46
aconitate	ME516481	1.54	0.46
2-deoxyglucose-6-phosphate	ME516462	1.54	0.46
2-Isopropylmalic acid	ME516482	1.54	0.46
trehalose-6-Phosphate	ME516461	1.53	0.47
D-sedoheptulose-1-7-phosphate	ME516452	1.53	0.47
glutathione disulfide	ME516391	1.53	0.47
glycolate	ME516464	1.68	0.32
2-oxobutanoate	ME516467	1.68	0.32
Beta-N-Acetylglucosamine	ME516431	1.68	0.32
Uric acid	ME516580	1.65	0.35
GMP	ME516543	1.66	0.34
acetyl-CoA	ME516421	1.66	0.34
glutathione	ME516495	1.66	0.34
xanthosine	ME516583	1.63	0.37
Citraconic acid	ME516474	1.61	0.39
glucosamine	ME516430	1.61	0.39
fumarate	ME516469	1.58	0.42
UDP-D-glucuronate	ME516567	1.59	0.41
Hydroxyisocaproic acid	ME516476	1.59	0.41
glucose-6-phosphate	ME516448	1.59	0.41
D-gluconate	ME516441	1.59	0.41
D-glucosamine-6-phosphate	ME516432	1.59	0.41
octulose-monophosphate (O8P-O1P)	ME516454	1.60	0.40
glucose-1-phosphate	ME516447	1.60	0.40
glyoxylate	ME516463	1.60	0.40
serine	ME516340	0.16	1.84
UTP	ME516560	0.27	1.73
N-Acetylputrescine	ME516399	1.02	0.98
3-hydroxybutyryl-CoA	ME516427	1.02	0.98
Cholesterol sulfate	ME516515	1.02	0.98
NAD+	ME516508	1.03	0.97
carnitine	ME516361	1.03	0.97
dCTP	ME516556	1.03	0.97
Phosphorylcholine	ME516517	1.04	0.96
dimethylglycine	ME516339	1.04	0.96
pantothenate	ME516502	1.04	0.96
Glycerophosphocholine	ME516511	1.05	0.95
purine	ME516579	1.05	0.95
homoserine	ME516345	1.07	0.93
2-Aminooctanoic acid	ME516360	1.07	0.93
cysteine	ME516346	1.07	0.93
UDP	ME516549	1.06	0.94
5^-Methylthioadenosine	ME516403	1.06	0.94
proline	ME516342	1.06	0.94
ethanolamine	ME516519	1.10	0.90
2-dehydro-D-gluconate	ME516440	1.09	0.91
histidine	ME516359	1.09	0.91
glucono-D-lactone	ME516437	0.95	1.05
tryptophan	ME516376	0.94	1.06
N6-Acetyl-L-lysine	ME516371	0.94	1.06
taurine	ME516520	0.94	1.06
succinyl-CoA-methylmalonyl-CoA	ME516428	1.00	1.00
deoxyinosine	ME516532	1.00	1.00
creatine	ME516347	1.00	1.00
3-phosphoglycerate	ME516439	1.00	1.00
coenzyme A	ME516420	1.00	1.00
Taurodeoxycholic acid	ME516516	0.99	1.01
4-aminobutyrate	ME516338	0.99	1.01
glutamine	ME516355	0.99	1.01
Kynurenic acid	ME516416	0.98	1.02
phenylalanine	ME516363	0.98	1.02
adenosine	ME516524	0.96	1.04
dCDP	ME516546	0.96	1.04
deoxyguanosine	ME516523	0.97	1.03
Diiodothyronine	ME516382	0.97	1.03
folate	ME516497	1.13	0.87
thymine	ME516572	1.12	0.88
Methylcysteine	ME516352	1.12	0.88
2-oxo-4-methylthiobutanoate	ME516411	1.12	0.88
Cystine	ME516379	1.12	0.88
uridine	ME516531	1.17	0.83
Phenyllactic acid	ME516414	1.14	0.86
betaine aldehyde	ME516396	1.14	0.86
deoxyadenosine	ME516522	1.14	0.86
alanine	ME516337	1.16	0.84
dCMP	ME516534	1.16	0.84
nicotinamide	ME516490	1.15	0.85
succinate	ME516472	1.15	0.85
asparagine	ME516350	1.19	0.81
N-Acetyl-L-alanine	ME516386	1.20	0.80
1-methylnicotinamide	ME516506	1.20	0.80
7-methylguanosine	ME516526	1.20	0.80
threonine	ME516344	1.23	0.77
phosphoenolpyruvate	ME516486	1.23	0.77
1-Methyladenosine	ME516525	1.23	0.77
glycerate	ME516434	1.23	0.77
Acetyllysine	ME516372	1.24	0.76
Thiamine pyrophosphate	ME516503	1.24	0.76
dGTP	ME516564	1.21	0.79
Fructose 1,6-bisphosphate	ME516455	1.22	0.78
aspartate	ME516351	1.22	0.78
Carbamoyl phosphate	ME516507	1.22	0.78
FMN	ME516504	0.89	1.11
acetylphosphate	ME516518	0.89	1.11
Alpha-ketoisovaleric acid	ME516471	0.89	1.11
Shikimate 3-phosphate	ME516418	0.90	1.10
NADH	ME516509	0.90	1.10
IDP	ME516553	0.90	1.10
dTTP	ME516558	0.90	1.10
histidinol	ME516334	0.90	1.10
dGDP	ME516552	0.92	1.08
dGMP	ME516540	0.92	1.08
Methylmalonic acid	ME516473	0.91	1.09
dihydroorotate	ME516387	0.91	1.09
methionine	ME516358	0.91	1.09
Geranyl-PP	ME516587	0.87	1.13
Xanthurenic acid	ME516417	0.88	1.12
betaine	ME516332	0.88	1.12
dTDP	ME516547	0.88	1.12
acadesine	ME516401	0.85	1.15
p-hydroxybenzoate	ME516592	0.86	1.14
glutamate	ME516357	0.86	1.14
myo-inositol	ME516438	0.86	1.14
6-phospho-D-glucono-1,5-lactone	ME516445	0.71	1.29
deoxyuridine	ME516529	0.70	1.30
NADPH	ME516408	0.70	1.30
sucrose	ME516456	0.74	1.26
quinolinate	ME516590	0.74	1.26
L-Acetylcarnitine	ME516586	0.74	1.26
cyclic bis(3->5) dimeric GMP	ME516603	0.74	1.26
3-hydroxy-3-methylglutaryl-CoA	ME516429	0.74	1.26
butyryl-CoA	ME516426	0.74	1.26
Indoleacrylic acid	ME516591	0.75	1.25
3-methylphenylacetic acid	ME516600	0.75	1.25
Imidazole	ME516394	0.75	1.25
allantoate	ME516389	0.73	1.27
dUMP	ME516544	0.73	1.27
Pyrophosphate	ME516510	0.72	1.28
Flavone	ME516585	0.72	1.28
hydroxyphenylpyruvate	ME516415	0.72	1.28
6-phospho-D-gluconate	ME516451	0.81	1.19
NADP+	ME516407	0.82	1.18
Kynurenine	ME516400	0.82	1.18
GTP	ME516565	0.82	1.18
hydroxyproline	ME516348	0.82	1.18
sarcosine	ME516383	0.83	1.17
choline	ME516397	0.83	1.17
indole	ME516398	0.83	1.17
lysine	ME516354	0.84	1.16
Hydroxyphenylacetic acid	ME516412	0.84	1.16
Indole-3-carboxylic acid	ME516589	0.84	1.16
3-Methylthiopropionate	ME516410	0.79	1.21
leucine-isoleucine	ME516393	0.79	1.21
tyrosine	ME516369	0.80	1.20
S-Adenosylmethioninamine	ME516404	0.80	1.20
p-aminobenzoate	ME516598	0.80	1.20
guanine	ME516574	0.80	1.20
lipoate	ME516489	0.80	1.20
Pyroglutamic acid	ME516385	0.78	1.22
OMP	ME516578	0.78	1.22
5-Methyl-tetrahydrofolate	ME516596	0.78	1.22
dTMP	ME516535	0.78	1.22
2,3-dihydroxybenzoic acid	ME516594	0.76	1.24
uracil	ME516576	0.76	1.24
homocysteic acid	ME516390	0.77	1.23
3-phospho-serine	ME516370	0.77	1.23
Guanosine diphosphate	ME516569	0.77	1.23
Urea	ME516584	0.63	1.37
allantoin	ME516601	0.63	1.37
glutathione disulfide-1	ME516392	0.63	1.37
riboflavin	ME516496	0.62	1.38
orotate	ME516577	0.62	1.38
O-acetyl-L-serine	ME516356	0.62	1.38
Guanidoacetic acid	ME516384	0.62	1.38
dATP	ME516562	0.62	1.38
Deoxycholic acid	ME516513	0.62	1.38
2,3-Diphosphoglyceric acid	ME516450	0.61	1.39
2-Ketohexanoic acid	ME516597	0.60	1.40
Maleic acid	ME516470	0.60	1.40
Nicotinamide ribotide	ME516539	0.65	1.35
5-phosphoribosyl-1-pyrophosphate	ME516459	0.65	1.35
Farnesyl pyrophosphate	ME516588	0.65	1.35
S-adenosyl-L-methionine	ME516406	0.64	1.36
D-glucarate	ME516443	0.64	1.36
citrulline	ME516367	0.64	1.36
Deoxyribose 5-phosphate	ME516528	0.64	1.36
GDP	ME516554	0.68	1.32
S-ribosyl-L-homocysteine	ME516402	0.67	1.33
spermidine	ME516335	0.67	1.33
Imidazoleacetic acid	ME516395	0.67	1.33
Atrolactic acid	ME516593	0.67	1.33
1-Methyl-Histidine	ME516364	0.67	1.33
7,8-dihydrofolate	ME516381	0.67	1.33
thymidine	ME516530	0.66	1.34
Ascorbic acid	ME516501	0.66	1.34
cytosine	ME516571	0.66	1.34
Cholic acid	ME516514	0.49	1.51
spermine	ME516409	0.50	1.50
Pyridoxamine	ME516491	0.50	1.50
aminoimidazole carboxamide riboNucleotides	ME516595	0.50	1.50
malonyl-CoA	ME516424	0.50	1.50
pyridoxine	ME516492	0.53	1.47
prephenate	ME516485	0.51	1.49
Xanthylic acid	ME516527	0.52	1.48
guanosine	ME516575	0.52	1.48
Cellobiose	ME516457	0.52	1.48
Citric acid	ME516487	0.52	1.48
cystathionine	ME516377	0.58	1.42
ornithine	ME516349	0.56	1.44
biotin	ME516493	0.56	1.44
lactate	ME516466	0.56	1.44
acetoacetyl-CoA	ME516423	0.54	1.46
Cyclic AMP	ME516545	0.55	1.45
nicotinate	ME516499	0.36	1.64
creatinine	ME516341	0.47	1.53
Phenylpropiolic acid	ME516599	0.46	1.54
CDP	ME516548	0.46	1.54
L-arginino-succinate	ME516380	0.46	1.54
Adenosine phosphosulfate	ME516550	0.41	1.59
dUTP	ME516557	0.40	1.60
Aminoadipic acid	ME516388	0.44	1.56
4-Pyridoxic acid	ME516505	0.43	1.57
adenine	ME516573	0.42	1.58

Factors:

F1	Genotype:Mutant \| Treatment:5 FU 2 weeks \| Batch:1f \| Source_Name[gating]:Lin– Scal1+ c-Kit+ (LSK)
F2	Genotype:Wild-type \| Treatment:5 FU 2 weeks \| Batch:1f \| Source_Name[gating]:Lin– Scal1+ c-Kit+ (LSK)

Data matrix