Clustering data with hclust algorithm for (Study ST002225)
(Analysis AN003634)Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cyclic AMP | ME538644 | 0.44 | 0.12 | 0.21 | 0.49 | 0.29 | 0.23 | 9.91 | 1.41 | 1.13 | 0.73 | 0.52 | 0.53 | 0.53 | 0.24 | 0.30 | 0.27 | 0.28 | 0.36 |
argininosuccinate | ME538607 | 1.05 | 0.22 | 1.05 | 0.12 | 0.14 | 0.17 | 1.09 | 1.76 | 5.64 | 0.16 | 0.29 | 0.14 | 0.12 | 0.06 | 0.10 | 0.11 | 0.11 | 0.17 |
N-acetylaspartate | ME538698 | 0.09 | 0.08 | 0.08 | 0.60 | 0.56 | 0.51 | 4.37 | 4.54 | 4.03 | 0.03 | 0.03 | 0.03 | 0.02 | 0.02 | 0.02 | 1.02 | 0.98 | 0.98 |
cystathionine | ME538645 | 0.09 | 0.05 | 0.07 | 0.18 | 0.13 | 0.10 | 4.69 | 4.78 | 5.30 | 0.02 | 0.04 | 0.02 | 0.05 | 0.06 | 0.04 | 0.75 | 0.68 | 0.47 |
N-acetylaspartylglutamate | ME538699 | 0.02 | 0.01 | 0.02 | 0.11 | 0.13 | 0.13 | 4.85 | 5.00 | 5.18 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.80 | 0.82 | 0.86 |
glycine | ME538677 | 0.45 | 0.07 | 0.22 | 0.45 | 0.07 | 0.06 | 5.34 | 4.19 | 3.50 | 0.27 | 0.16 | 0.04 | 0.74 | 0.54 | 0.49 | 0.61 | 0.43 | 0.38 |
phosphocreatine | ME538713 | 0.10 | 0.08 | 0.09 | 0.01 | 0.01 | 0.01 | 4.32 | 4.27 | 3.64 | 0.52 | 0.57 | 0.45 | 0.54 | 0.48 | 0.44 | 0.83 | 0.81 | 0.82 |
4-hydroxyproline | ME538598 | 0.22 | 0.08 | 0.23 | 0.25 | 0.08 | 0.11 | 5.17 | 3.21 | 2.68 | 0.55 | 0.44 | 0.40 | 0.68 | 0.44 | 0.58 | 1.13 | 0.87 | 0.86 |
N-acetylglutamate | ME538700 | 0.62 | 0.50 | 0.40 | 0.83 | 0.64 | 0.49 | 4.35 | 3.54 | 2.33 | 0.46 | 0.42 | 0.35 | 0.56 | 0.47 | 0.31 | 0.66 | 0.59 | 0.48 |
carnitine C5_m+4 | ME538631 | 2.68 | 1.15 | 0.10 | 3.41 | 0.95 | 0.07 | 0.18 | 1.08 | 0.24 | NA | 0.92 | 0.78 | NA | 0.86 | 0.61 | NA | 0.14 | 0.24 |
aconitate_m+2 | ME538601 | 4.00 | 0.06 | 0.07 | 2.76 | NA | NA | 1.42 | NA | NA | 0.13 | 0.11 | 0.13 | 0.27 | 0.63 | 0.22 | 0.51 | 0.15 | 0.22 |
citrate_m+2 | ME538636 | 4.16 | 0.04 | NA | 3.59 | 0.06 | 0.00 | 2.02 | 0.09 | 0.01 | 0.16 | 0.48 | 0.42 | 0.37 | 1.27 | 0.95 | 1.26 | 0.25 | 0.19 |
carnitine C3_m+0 | ME538620 | 2.42 | 0.29 | 0.41 | 3.53 | 0.47 | 0.55 | 1.76 | 1.03 | 1.18 | 0.91 | 0.48 | 0.54 | 0.72 | 0.27 | 0.35 | 1.91 | 0.70 | 0.47 |
carnitine C3_m+1 | ME538621 | 2.48 | 0.22 | 0.39 | 3.67 | 0.44 | 0.53 | 1.79 | 1.03 | 1.19 | 0.91 | 0.46 | 0.53 | 0.72 | 0.23 | 0.33 | 1.95 | 0.70 | 0.45 |
carnitine C5_m+3 | ME538630 | 3.96 | 0.69 | 0.31 | 4.68 | 0.76 | 0.31 | 2.15 | 1.73 | 0.67 | 0.57 | 0.22 | 0.22 | 0.32 | 0.17 | 0.18 | 0.57 | 0.27 | 0.17 |
carnitine C5_m+0 | ME538628 | 3.63 | 0.84 | 0.32 | 4.24 | 0.74 | 0.22 | 2.63 | 1.77 | 0.67 | 0.71 | 0.39 | 0.18 | 0.39 | 0.16 | 0.08 | 0.59 | 0.32 | 0.10 |
carnitine C5_m+1 | ME538629 | 3.85 | 0.79 | 0.28 | 4.52 | 0.71 | 0.18 | 2.78 | 1.84 | 0.64 | 0.65 | 0.32 | 0.13 | 0.32 | 0.10 | 0.04 | 0.54 | 0.26 | 0.06 |
carnitine C2_m+2 | ME538619 | 1.68 | 0.11 | 0.08 | 2.23 | 0.14 | 0.05 | 7.09 | 0.62 | 0.03 | 0.36 | 0.59 | 0.77 | 0.44 | 0.60 | 0.46 | 0.85 | 0.93 | 0.97 |
carnitine C2_m+0 | ME538617 | 0.75 | 0.60 | 0.68 | 1.05 | 0.93 | 0.81 | 4.30 | 1.14 | 0.41 | 0.56 | 0.69 | 0.90 | 0.65 | 0.55 | 0.53 | 1.10 | 1.32 | 1.02 |
carnitine C2_m+1 | ME538618 | 0.77 | 0.58 | 0.67 | 1.08 | 0.91 | 0.80 | 4.42 | 1.12 | 0.39 | 0.55 | 0.68 | 0.89 | 0.65 | 0.55 | 0.53 | 1.09 | 1.30 | 1.01 |
cysteate | ME538646 | 0.22 | 0.17 | 0.80 | 0.29 | 0.22 | 0.41 | 0.27 | 0.27 | 0.23 | 0.31 | 0.36 | 1.65 | 0.29 | 0.18 | 6.59 | 1.38 | 0.52 | 3.85 |
oxidized glutathione | ME538709 | 0.27 | 0.25 | 0.77 | 0.45 | 0.33 | 0.37 | 0.59 | 0.74 | 0.60 | 0.26 | 0.28 | 1.07 | 0.49 | 0.46 | 3.47 | 2.19 | 1.06 | 4.35 |
malate_m+2 | ME538694 | 0.27 | 0.49 | 0.95 | 0.40 | 0.83 | 0.71 | 0.02 | 1.32 | 1.79 | 0.24 | 0.43 | 2.11 | 0.31 | 0.56 | 3.91 | 0.62 | 0.45 | 2.44 |
malate_m+0 | ME538692 | 0.46 | 0.48 | 1.10 | 0.62 | 0.65 | 0.82 | 0.18 | 0.77 | 1.92 | 0.54 | 0.42 | 1.44 | 0.65 | 0.45 | 3.55 | 1.04 | 0.40 | 2.52 |
malate_m+1 | ME538693 | 0.45 | 0.47 | 1.10 | 0.62 | 0.65 | 0.82 | 0.16 | 0.78 | 1.95 | 0.53 | 0.41 | 1.45 | 0.64 | 0.44 | 3.57 | 1.04 | 0.40 | 2.53 |
fumarate_m+0 | ME538653 | 0.48 | 0.49 | 1.08 | 0.64 | 0.67 | 0.84 | 0.16 | 0.80 | 2.08 | 0.56 | 0.42 | 1.40 | 0.68 | 0.45 | 3.42 | 1.00 | 0.40 | 2.43 |
fumarate_m+1 | ME538654 | 0.44 | 0.47 | 1.09 | 0.64 | 0.66 | 0.84 | 0.09 | 0.77 | 2.19 | 0.56 | 0.39 | 1.43 | 0.64 | 0.41 | 3.51 | 0.98 | 0.34 | 2.54 |
fumarate_m+3 | ME538655 | 0.44 | 0.47 | 1.09 | 0.64 | 0.66 | 0.84 | 0.09 | 0.77 | 2.19 | 0.56 | 0.39 | 1.43 | 0.64 | 0.41 | 3.51 | 0.98 | 0.34 | 2.54 |
glutamate_m+3 | ME538666 | 0.02 | 0.13 | 0.06 | 0.05 | 0.17 | 0.06 | NA | 0.07 | NA | NA | 0.20 | 3.82 | NA | 0.12 | 3.19 | NA | 0.07 | 0.25 |
proline_m+3 | ME538719 | NA | NA | 0.18 | 0.16 | 0.11 | 0.09 | 0.05 | 0.16 | 0.06 | 0.09 | 0.08 | 1.16 | 0.09 | 0.12 | 5.05 | 0.08 | 0.16 | 1.30 |
citrate_m+3 | ME538637 | 0.61 | 0.37 | 0.06 | 0.73 | 0.11 | 0.06 | 0.87 | 0.13 | 0.03 | NA | 0.73 | 1.71 | 0.07 | 3.64 | 2.99 | 0.16 | 1.50 | 1.03 |
aspartate_m+3 | ME538612 | 0.19 | 1.27 | 0.08 | 0.25 | 1.00 | 0.04 | 0.17 | 0.47 | NA | 0.01 | 2.16 | 2.31 | 0.01 | 1.76 | 2.95 | 0.01 | 0.66 | 1.19 |
malate_m+3 | ME538695 | 0.21 | 1.24 | 0.05 | 0.77 | 1.03 | 0.05 | 0.18 | 1.08 | 0.06 | NA | 1.15 | 1.02 | NA | 2.51 | 2.21 | NA | 0.77 | 0.85 |
2-hydroxyglutarate_m+2 | ME538593 | 0.61 | 0.29 | 0.16 | 1.17 | 1.00 | 0.39 | 0.19 | 0.19 | NA | 0.29 | 0.36 | 1.82 | 1.69 | 1.76 | 3.24 | 0.96 | 0.58 | 0.36 |
2-oxoglutarate_m+2 | ME538596 | 0.60 | 0.65 | NA | 2.63 | 0.58 | 0.85 | 0.27 | 0.57 | 0.29 | 0.23 | 0.24 | 0.93 | 0.47 | 0.38 | 2.95 | 0.20 | NA | NA |
carnitine C3_m+2 | ME538622 | 1.41 | 0.14 | 0.21 | 2.41 | 0.25 | 0.17 | 0.89 | 0.61 | 0.25 | 0.31 | 0.92 | 0.76 | 0.31 | 0.56 | 0.60 | 0.67 | 3.79 | 3.60 |
carnitine C3_m+3 | ME538623 | 2.25 | 0.32 | 0.16 | 3.53 | 0.39 | 0.12 | 1.32 | 0.69 | 0.06 | 0.32 | 1.21 | 0.86 | 0.31 | 0.96 | 0.81 | 0.90 | 1.76 | 2.03 |
NADH | ME538703 | 0.27 | 0.05 | 0.15 | 0.16 | 0.08 | NA | 1.86 | 1.68 | 0.19 | 0.13 | 3.07 | 0.41 | 2.26 | 0.73 | 0.74 | 0.83 | 1.17 | 3.06 |
cystine | ME538647 | 2.77 | 1.07 | 1.49 | 0.36 | 0.35 | 0.57 | 0.32 | 0.37 | 0.14 | 0.08 | 2.18 | 1.03 | 0.35 | 1.48 | 0.83 | 0.28 | 1.69 | 1.16 |
mevalonate-5-pyrophosphate | ME538697 | 0.26 | 0.65 | 1.29 | 0.36 | 1.00 | 1.56 | 0.21 | 0.64 | 0.95 | 1.27 | 2.34 | 2.85 | 0.25 | 0.70 | 1.25 | 0.30 | 0.82 | 1.31 |
aspartate_m+2 | ME538611 | 0.35 | 0.99 | 1.26 | 0.37 | 0.93 | 0.90 | 0.07 | 0.93 | 1.20 | 0.61 | 1.32 | 3.33 | 0.34 | 0.77 | 2.66 | 0.25 | 0.63 | 1.09 |
glutamate_m+2 | ME538665 | 0.59 | 0.92 | 0.85 | 0.70 | 0.93 | 0.70 | 0.49 | 1.11 | 0.85 | 0.47 | 1.26 | 2.43 | 0.56 | 1.26 | 2.70 | 0.41 | 0.77 | 1.01 |
inosine | ME538684 | 0.83 | 0.32 | 0.27 | 1.38 | 0.50 | 0.39 | 0.62 | 0.78 | 0.67 | 1.79 | 2.11 | 2.40 | 1.53 | 1.29 | 0.92 | 1.36 | 0.66 | 0.18 |
succinate_m+2 | ME538732 | 0.55 | 0.48 | 0.60 | NA | NA | 0.53 | 0.60 | 0.97 | 0.64 | 0.66 | 1.30 | 1.14 | 0.73 | 1.07 | 2.37 | NA | 0.61 | NA |
glucose 1-phosphate | ME538661 | 0.31 | 0.29 | 0.42 | 0.34 | 0.39 | 0.31 | 1.42 | 1.26 | 1.32 | 1.63 | 1.77 | 1.55 | 2.02 | 1.72 | 1.99 | 0.39 | 0.44 | 0.42 |
succinate_m+0 | ME538730 | 0.40 | 0.30 | 0.32 | 0.33 | 0.32 | 0.25 | 0.34 | 0.73 | 1.02 | 1.45 | 1.85 | 1.65 | 1.98 | 2.02 | 2.16 | 0.50 | 0.77 | 0.47 |
succinate_m+1 | ME538731 | 0.49 | 0.38 | 0.38 | 0.42 | 0.42 | 0.34 | 0.30 | 0.84 | 1.01 | 1.47 | 1.87 | 1.75 | 1.99 | 2.02 | 2.27 | 0.58 | 0.86 | 0.60 |
carnitine C4_m+2 | ME538626 | 1.22 | 0.40 | 0.27 | 2.57 | 0.78 | 0.21 | 2.21 | 3.11 | 0.51 | 0.14 | 0.95 | 0.72 | 0.30 | 0.96 | 1.06 | 0.51 | 0.85 | 1.22 |
carnitine C4_m+3 | ME538627 | 0.86 | 0.34 | NA | 1.87 | 0.34 | 0.20 | 1.18 | 1.62 | NA | 0.28 | 0.99 | 0.50 | 0.11 | 0.94 | 1.14 | NA | 0.32 | 1.30 |
2-oxoglutarate_m+0 | ME538594 | 1.56 | 1.00 | 0.89 | 2.43 | 1.51 | 1.50 | 0.28 | 0.67 | 0.98 | 1.29 | 0.54 | 0.48 | 1.76 | 0.82 | 0.81 | 0.62 | 0.47 | 0.37 |
2-oxoglutarate_m+1 | ME538595 | 1.60 | 1.01 | 0.88 | 2.48 | 1.53 | 1.52 | 0.26 | 0.64 | 0.97 | 1.31 | 0.51 | 0.47 | 1.78 | 0.82 | 0.83 | 0.59 | 0.45 | 0.34 |
ketoleucine+ketoisoleucine_m+6 | ME538685 | 1.35 | 0.33 | 0.87 | 2.12 | 0.71 | 0.90 | 1.65 | 1.69 | 2.15 | 0.51 | 0.18 | 0.30 | 1.08 | 0.41 | 0.61 | 1.24 | 0.86 | 1.03 |
carnitine C4_m+0 | ME538624 | 0.97 | 0.56 | 0.76 | 1.94 | 0.99 | 0.88 | 1.79 | 2.38 | 2.42 | 0.48 | 0.52 | 0.45 | 0.58 | 0.39 | 0.44 | 0.94 | 0.68 | 0.81 |
carnitine C4_m+1 | ME538625 | 0.97 | 0.55 | 0.75 | 1.96 | 0.98 | 0.87 | 1.82 | 2.41 | 2.45 | 0.46 | 0.52 | 0.44 | 0.57 | 0.39 | 0.44 | 0.94 | 0.67 | 0.81 |
gluconate | ME538659 | 0.33 | 0.24 | 0.28 | 0.54 | 0.45 | 0.40 | 2.27 | 2.19 | 2.33 | 0.48 | 0.58 | 0.56 | 0.75 | 2.55 | 0.63 | 1.31 | 1.15 | 0.96 |
betaine | ME538615 | 0.56 | 0.43 | 0.53 | 0.96 | 0.84 | 0.74 | 2.69 | 2.84 | 2.59 | 0.71 | 0.81 | 0.66 | 0.43 | 0.42 | 0.39 | 0.87 | 0.82 | 0.71 |
serine | ME538728 | 0.39 | 0.18 | 0.42 | 0.42 | 0.17 | 0.22 | 3.30 | 2.61 | 3.01 | 0.74 | 0.78 | 0.63 | 0.94 | 0.85 | 0.82 | 0.84 | 0.74 | 0.93 |
asparagine | ME538608 | 0.54 | 0.23 | 0.47 | 0.55 | 0.26 | 0.26 | 2.54 | 2.48 | 2.61 | 1.09 | 0.86 | 0.68 | 1.15 | 0.82 | 0.88 | 1.01 | 0.74 | 0.82 |
alanine | ME538604 | 0.60 | 0.46 | 0.64 | 0.67 | 0.58 | 0.57 | 2.75 | 1.99 | 2.55 | 0.74 | 0.73 | 0.67 | 0.86 | 0.72 | 0.80 | 0.91 | 0.80 | 0.97 |
threonine | ME538735 | 0.45 | 0.22 | 0.57 | 0.48 | 0.27 | 0.32 | 2.98 | 2.07 | 2.64 | 0.75 | 0.84 | 0.78 | 0.97 | 0.77 | 0.98 | 0.97 | 0.82 | 1.10 |
ornithine | ME538707 | 0.36 | 0.53 | 0.73 | 0.56 | 0.23 | 0.57 | 2.10 | 1.72 | 2.62 | 0.54 | 0.59 | 0.86 | 0.83 | 0.91 | 0.78 | 1.47 | 1.21 | 1.39 |
UDP-GlcNac | ME538739 | 0.42 | 0.45 | 0.84 | 0.42 | 0.65 | 0.68 | 1.88 | 2.23 | 2.29 | 0.81 | 0.87 | 0.87 | 0.73 | 0.61 | 1.04 | 1.06 | 0.90 | 1.26 |
glutamine_m+2 | ME538669 | 0.37 | 0.14 | 0.28 | 0.17 | 0.13 | 0.08 | 1.52 | 2.19 | 2.97 | 0.69 | 1.10 | 0.41 | 1.63 | 0.91 | 1.12 | 0.86 | 1.02 | 1.08 |
glutamine_m+0 | ME538667 | 0.67 | 0.23 | 0.68 | 0.59 | 0.21 | 0.30 | 1.41 | 1.68 | 2.27 | 0.92 | 1.12 | 0.78 | 1.47 | 1.01 | 1.18 | 1.09 | 1.13 | 1.24 |
glutamine_m+1 | ME538668 | 0.67 | 0.28 | 0.67 | 0.61 | 0.27 | 0.34 | 1.37 | 1.66 | 2.30 | 0.92 | 1.11 | 0.78 | 1.47 | 0.99 | 1.18 | 1.07 | 1.10 | 1.20 |
4-hydroxyphenyllactate | ME538597 | 0.76 | 0.40 | 0.35 | 1.18 | 0.40 | 0.32 | 2.74 | 1.52 | 0.63 | 1.01 | 0.93 | 0.67 | 1.57 | 0.94 | 0.79 | 1.81 | 1.16 | 0.82 |
sedoheptulose 7-phosphate | ME538727 | 0.75 | 0.58 | 0.62 | 0.61 | 0.60 | 0.41 | 1.65 | 1.38 | 1.49 | 0.34 | 0.59 | 0.15 | 2.14 | 1.82 | 1.43 | 1.19 | 1.31 | 0.94 |
S-lactoylglutathione | ME538729 | 0.62 | 0.36 | 0.22 | 1.81 | 1.28 | 0.70 | 1.09 | 1.07 | 0.86 | 0.69 | 0.63 | 0.40 | 1.06 | 0.66 | 0.34 | 2.41 | 2.04 | 1.75 |
glycerylphosphorylcholine | ME538676 | 1.04 | 0.97 | 1.43 | 0.59 | 0.56 | 0.59 | 2.00 | 1.80 | 2.06 | 0.33 | 0.28 | 0.51 | 0.43 | 0.39 | 0.68 | 1.46 | 1.42 | 1.46 |
S-Succinylglutathione | ME538723 | 0.53 | 0.45 | 0.55 | 0.99 | 0.95 | 0.85 | 2.17 | 2.20 | 2.11 | 0.31 | 0.37 | 0.34 | 0.56 | 0.42 | 0.41 | 1.68 | 1.63 | 1.49 |
CMP | ME538639 | 0.68 | 0.82 | 0.77 | 1.03 | 1.24 | 0.91 | 1.24 | 1.64 | 1.61 | 0.21 | 0.61 | 0.84 | 0.50 | 0.83 | 0.54 | 1.32 | 1.58 | 1.64 |
glutathione reduced_m+3 | ME538673 | 0.35 | 0.33 | 0.71 | 0.97 | 0.92 | 0.97 | 1.24 | 1.26 | 1.38 | 0.47 | 0.63 | 0.63 | 0.72 | 0.59 | 0.70 | 2.00 | 2.03 | 2.04 |
glutathione reduced_m+0 | ME538670 | 0.56 | 0.52 | 0.77 | 0.98 | 0.98 | 0.98 | 1.13 | 1.24 | 1.44 | 0.63 | 0.72 | 0.73 | 0.84 | 0.73 | 0.59 | 1.74 | 1.73 | 1.68 |
glutathione reduced_m+1 | ME538671 | 0.54 | 0.51 | 0.76 | 0.98 | 0.97 | 0.98 | 1.14 | 1.24 | 1.45 | 0.62 | 0.71 | 0.72 | 0.83 | 0.72 | 0.59 | 1.76 | 1.76 | 1.70 |
glutathione reduced_m+2 | ME538672 | 0.53 | 0.50 | 0.78 | 0.98 | 0.97 | 0.97 | 1.14 | 1.25 | 1.46 | 0.61 | 0.72 | 0.74 | 0.82 | 0.72 | 0.60 | 1.74 | 1.77 | 1.72 |
proline_m+2 | ME538718 | 0.52 | 0.51 | 0.77 | 0.69 | 0.67 | 0.60 | 1.39 | 1.70 | 1.59 | 0.34 | 0.33 | 0.69 | 0.93 | 1.03 | 1.76 | 1.27 | 1.42 | 1.80 |
proline_m+0 | ME538716 | 0.62 | 0.46 | 0.74 | 0.79 | 0.63 | 0.60 | 1.73 | 1.78 | 1.86 | 0.43 | 0.41 | 0.39 | 1.14 | 1.00 | 0.88 | 1.58 | 1.51 | 1.46 |
proline_m+1 | ME538717 | 0.62 | 0.46 | 0.74 | 0.79 | 0.63 | 0.60 | 1.72 | 1.78 | 1.87 | 0.43 | 0.40 | 0.39 | 1.14 | 1.00 | 0.88 | 1.57 | 1.50 | 1.46 |
adenosine | ME538602 | 0.82 | 0.81 | 1.34 | 1.04 | 1.64 | 2.01 | 1.20 | 1.04 | 1.57 | 0.49 | 0.57 | 0.74 | 1.16 | 0.88 | 1.03 | 0.34 | 0.52 | 0.80 |
aconitate_m+0 | ME538599 | 1.37 | 0.94 | 0.68 | 1.10 | 0.88 | 0.63 | 0.78 | 0.58 | 0.31 | 1.69 | 1.00 | 0.88 | 1.93 | 1.23 | 0.92 | 1.21 | 1.11 | 0.76 |
aconitate_m+1 | ME538600 | 1.50 | 0.93 | 0.61 | 1.20 | 0.87 | 0.58 | 0.80 | 0.53 | 0.21 | 1.74 | 0.96 | 0.86 | 2.01 | 1.25 | 0.89 | 1.21 | 1.10 | 0.74 |
2-hydroxyglutarate_m+0 | ME538591 | 1.13 | 0.96 | 0.77 | 1.44 | 1.18 | 0.96 | 0.46 | 0.47 | 0.65 | 0.91 | 0.93 | 0.83 | 1.69 | 1.52 | 1.02 | 1.39 | 0.97 | 0.72 |
2-hydroxyglutarate_m+1 | ME538592 | 1.14 | 0.94 | 0.76 | 1.47 | 1.18 | 0.96 | 0.43 | 0.44 | 0.63 | 0.92 | 0.93 | 0.83 | 1.71 | 1.53 | 1.05 | 1.40 | 0.96 | 0.71 |
citrate_m+0 | ME538634 | 1.08 | 0.88 | 0.77 | 0.92 | 0.78 | 0.71 | 0.80 | 0.86 | 0.62 | 1.14 | 0.98 | 0.88 | 1.53 | 2.15 | 0.95 | 1.07 | 1.02 | 0.88 |
citrate_m+1 | ME538635 | 1.13 | 0.87 | 0.75 | 0.95 | 0.77 | 0.69 | 0.82 | 0.84 | 0.61 | 1.14 | 0.97 | 0.87 | 1.54 | 2.16 | 0.96 | 1.07 | 1.02 | 0.86 |
hypotaurine | ME538681 | 0.69 | 0.55 | 0.42 | 1.45 | 1.45 | 0.95 | 1.25 | 1.11 | 0.79 | 1.81 | 1.58 | 1.03 | 0.86 | 0.62 | 0.38 | 1.07 | 1.21 | 0.58 |
CDP | ME538633 | 0.94 | 0.81 | 0.92 | 0.99 | 1.08 | 0.57 | 0.98 | 1.67 | 1.06 | 0.34 | 0.82 | 0.73 | 0.69 | 1.39 | 0.83 | 1.14 | 1.46 | 1.59 |
dTTP | ME538651 | 0.96 | 1.08 | 1.02 | 0.88 | 0.93 | 0.52 | 1.06 | 1.58 | 1.32 | 0.27 | 0.64 | 0.41 | 0.69 | 1.43 | 0.64 | 1.47 | 1.36 | 1.75 |
GTP | ME538679 | 0.90 | 0.78 | 0.85 | 0.93 | 1.11 | 0.51 | 0.65 | 1.54 | 0.79 | 0.37 | 1.18 | 1.04 | 0.70 | 2.73 | 0.74 | 0.70 | 1.07 | 1.41 |
UTP | ME538743 | 1.01 | 0.83 | 0.73 | 1.23 | 1.13 | 0.56 | 0.85 | 1.48 | 0.90 | 0.51 | 0.97 | 0.72 | 0.73 | 2.46 | 0.81 | 0.96 | 1.11 | 1.03 |
CTP | ME538643 | 0.91 | 0.75 | 0.80 | 0.95 | 1.05 | 0.46 | 0.87 | 1.76 | 1.00 | 0.30 | 0.76 | 0.61 | 0.61 | 2.30 | 0.76 | 1.14 | 1.41 | 1.56 |
ATP | ME538613 | 0.81 | 0.78 | 0.86 | 0.93 | 1.12 | 0.66 | 0.87 | 1.65 | 1.16 | 0.47 | 1.00 | 0.94 | 0.68 | 2.02 | 0.76 | 0.78 | 1.07 | 1.43 |
UDP | ME538738 | 0.94 | 0.83 | 0.79 | 1.15 | 1.09 | 0.69 | 1.01 | 1.47 | 1.00 | 0.58 | 0.98 | 0.81 | 0.81 | 1.76 | 0.85 | 1.01 | 1.16 | 1.04 |
glucose | ME538660 | 1.65 | 0.87 | 1.04 | 0.91 | 0.65 | 0.67 | 0.96 | 1.52 | 0.78 | 0.64 | 1.51 | 0.76 | 0.74 | 1.14 | 0.78 | 1.04 | 1.61 | 0.76 |
hypoxanthine | ME538682 | 1.60 | 0.62 | 0.79 | 1.25 | 0.47 | 0.48 | 1.09 | 1.65 | 0.57 | 0.70 | 1.78 | 1.13 | 0.84 | 1.46 | 0.84 | 0.89 | 1.34 | 0.50 |
carnitine C5_m+5 | ME538632 | 1.50 | 1.15 | 0.42 | 1.87 | 1.17 | 0.36 | 1.06 | 1.67 | 0.64 | 0.88 | 1.24 | 0.68 | 1.07 | 1.31 | 0.66 | 0.61 | 1.21 | 0.51 |
NADPH | ME538705 | 1.38 | 1.12 | 0.83 | 1.37 | 1.21 | 0.52 | 1.08 | 1.22 | 0.60 | 0.68 | 1.41 | 0.76 | 1.14 | 1.58 | 0.67 | 0.80 | 0.90 | 0.73 |
leucine+isoleucine_m+0 | ME538687 | 0.57 | 0.56 | 1.76 | 0.67 | 0.58 | 0.66 | 1.59 | 1.15 | 1.22 | 1.54 | 1.01 | 1.09 | 1.25 | 1.05 | 0.84 | 0.86 | 0.75 | 0.85 |
leucine+isoleucine_m+1 | ME538688 | 0.48 | 0.42 | 2.03 | 0.52 | 0.45 | 0.57 | 1.54 | 1.05 | 1.19 | 1.81 | 1.00 | 1.21 | 1.41 | 1.12 | 0.88 | 0.84 | 0.64 | 0.84 |
aspartate_m+0 | ME538609 | 0.76 | 0.92 | 1.41 | 0.71 | 1.03 | 1.26 | 0.31 | 0.83 | 1.90 | 1.30 | 1.50 | 1.45 | 0.76 | 0.80 | 1.03 | 0.59 | 0.62 | 0.83 |
aspartate_m+1 | ME538610 | 0.75 | 0.92 | 1.41 | 0.70 | 1.03 | 1.26 | 0.30 | 0.83 | 1.90 | 1.30 | 1.50 | 1.48 | 0.75 | 0.79 | 1.05 | 0.58 | 0.61 | 0.82 |
carnitine | ME538616 | 0.75 | 0.70 | 0.80 | 1.32 | 1.39 | 1.28 | 0.62 | 1.18 | 1.19 | 1.72 | 1.76 | 1.49 | 0.82 | 0.69 | 0.69 | 0.56 | 0.53 | 0.53 |
pyruvate | ME538721 | 1.40 | 0.76 | 0.86 | 1.12 | 1.24 | 1.15 | 0.79 | 1.54 | 1.46 | 1.05 | 1.57 | 1.20 | 0.77 | 0.73 | 0.66 | 0.56 | 0.64 | 0.49 |
deoxycarnitine | ME538648 | 0.64 | 0.59 | 0.66 | 1.23 | 1.19 | 1.10 | 1.75 | 1.70 | 1.71 | 1.16 | 1.14 | 1.03 | 0.61 | 0.52 | 0.55 | 0.84 | 0.80 | 0.77 |
beta-alanine | ME538614 | 0.98 | 0.90 | 0.84 | 0.91 | 0.92 | 0.76 | 1.94 | 1.84 | 1.59 | 1.10 | 1.06 | 0.86 | 0.95 | 0.83 | 0.69 | 0.66 | 0.59 | 0.59 |
S-adenosylhomocysteine | ME538724 | 0.72 | 0.51 | 0.75 | 0.96 | 0.96 | 0.90 | 1.66 | 1.66 | 1.73 | 0.76 | 0.90 | 0.93 | 1.08 | 0.90 | 0.79 | 0.86 | 0.90 | 1.02 |
citrulline | ME538638 | 0.98 | 0.39 | 0.85 | 1.19 | 0.40 | 0.49 | 1.50 | 1.17 | 1.09 | 1.17 | 1.06 | 1.03 | 1.25 | 1.02 | 1.05 | 1.31 | 0.90 | 1.15 |
glycerol 3-phosphate | ME538675 | 0.59 | 0.62 | 0.83 | 0.59 | 0.54 | 0.52 | 1.66 | 1.23 | 1.34 | 0.96 | 1.27 | 1.21 | 1.57 | 1.14 | 1.29 | 0.95 | 0.68 | 1.00 |
methionine | ME538696 | 0.79 | 0.37 | 0.81 | 0.71 | 0.38 | 0.45 | 1.90 | 1.97 | 2.16 | 1.13 | 1.41 | 1.12 | 0.72 | 0.71 | 0.54 | 0.93 | 1.01 | 0.89 |
phosphorylcholine | ME538715 | 0.40 | 0.39 | 0.61 | 0.56 | 0.68 | 0.77 | 1.61 | 1.75 | 1.89 | 1.27 | 1.38 | 1.39 | 0.89 | 0.76 | 0.87 | 0.90 | 0.92 | 0.96 |
valine | ME538744 | 0.90 | 0.46 | 0.96 | 0.79 | 0.55 | 0.62 | 1.46 | 1.42 | 1.46 | 1.18 | 1.41 | 1.25 | 0.75 | 0.73 | 0.78 | 1.03 | 1.06 | 1.20 |
leucine+isoleucine_m+5 | ME538689 | 0.83 | 0.38 | 0.87 | 0.70 | 0.45 | 0.53 | 1.29 | 1.39 | 1.61 | 1.14 | 1.45 | 1.41 | 0.74 | 0.71 | 0.94 | 1.06 | 1.11 | 1.40 |
leucine+isoleucine_m+6 | ME538690 | 0.83 | 0.41 | 0.86 | 0.71 | 0.46 | 0.55 | 1.31 | 1.40 | 1.59 | 1.13 | 1.42 | 1.38 | 0.74 | 0.72 | 0.94 | 1.06 | 1.10 | 1.38 |
histidine | ME538680 | 0.69 | 0.38 | 0.77 | 0.60 | 0.39 | 0.48 | 1.58 | 1.44 | 1.55 | 1.25 | 1.47 | 1.42 | 0.86 | 0.87 | 0.93 | 1.01 | 1.07 | 1.25 |
tyrosine | ME538737 | 0.71 | 0.37 | 0.83 | 0.71 | 0.45 | 0.53 | 1.66 | 1.44 | 1.82 | 1.24 | 1.37 | 1.35 | 0.82 | 0.68 | 0.85 | 0.99 | 0.97 | 1.24 |
phenylalanine | ME538712 | 0.77 | 0.35 | 0.92 | 0.69 | 0.45 | 0.54 | 1.48 | 1.45 | 1.64 | 1.14 | 1.38 | 1.32 | 0.82 | 0.76 | 0.91 | 1.02 | 1.02 | 1.33 |
tryptophan | ME538736 | 0.74 | 0.37 | 0.93 | 0.71 | 0.46 | 0.55 | 1.53 | 1.45 | 1.67 | 1.16 | 1.37 | 1.35 | 0.85 | 0.70 | 0.89 | 0.99 | 0.97 | 1.32 |
CMP-acetylneuraminate | ME538640 | 0.64 | 0.58 | 0.80 | 0.76 | 0.84 | 0.82 | 1.65 | 1.39 | 1.57 | 0.88 | 1.04 | 0.96 | 0.82 | 0.71 | 0.84 | 1.30 | 1.17 | 1.25 |
GDP fucose | ME538657 | 0.68 | 0.54 | 0.73 | 0.90 | 0.80 | 0.72 | 1.53 | 1.37 | 1.45 | 0.97 | 1.11 | 1.39 | 0.92 | 0.71 | 0.90 | 1.08 | 0.83 | 1.35 |
GDP-glucose | ME538658 | 1.22 | 0.62 | 0.96 | 1.39 | 0.91 | 0.82 | 1.01 | 0.84 | 0.98 | 0.60 | 0.72 | 0.63 | 1.61 | 0.79 | 0.89 | 1.33 | 1.23 | 1.45 |
phosphoenolpyruvate | ME538714 | 1.49 | 1.27 | 1.41 | 1.21 | 1.00 | 1.15 | 0.82 | 1.09 | 1.44 | 0.75 | 0.78 | 0.55 | 1.09 | 0.77 | 0.62 | 1.11 | 0.97 | 0.48 |
glutamate_m+0 | ME538663 | 1.00 | 0.85 | 1.14 | 1.04 | 1.02 | 1.08 | 0.67 | 1.17 | 1.55 | 0.98 | 0.92 | 0.96 | 1.16 | 0.87 | 1.10 | 0.86 | 0.76 | 0.86 |
glutamate_m+1 | ME538664 | 1.00 | 0.86 | 1.14 | 1.04 | 1.02 | 1.08 | 0.67 | 1.17 | 1.54 | 0.97 | 0.92 | 0.97 | 1.16 | 0.87 | 1.13 | 0.86 | 0.76 | 0.86 |
N-acetylneuraminic acid | ME538701 | 1.40 | 1.05 | 1.49 | 1.04 | 1.04 | 1.19 | 1.08 | 1.01 | 1.24 | 0.75 | 1.03 | 0.94 | 1.09 | 0.90 | 0.93 | 0.60 | 0.60 | 0.61 |
pantothenate | ME538710 | 0.86 | 0.88 | 1.16 | 1.04 | 1.21 | 1.30 | 1.08 | 1.11 | 1.27 | 0.86 | 0.93 | 0.91 | 1.30 | 1.04 | 1.23 | 0.58 | 0.58 | 0.68 |
S-adenosylmethionine | ME538725 | 1.20 | 0.84 | 1.29 | 0.97 | 1.28 | 1.28 | 0.98 | 1.11 | 1.18 | 0.74 | 0.85 | 0.75 | 1.05 | 1.09 | 1.01 | 0.79 | 0.79 | 0.79 |
glyceraldehyde 3-phosphate | ME538674 | 0.57 | 0.57 | 0.77 | 0.99 | 1.16 | 1.29 | 1.16 | 0.93 | 1.16 | 0.95 | 1.35 | 1.23 | 1.16 | 0.83 | 0.95 | 0.95 | 0.79 | 1.19 |
creatine | ME538641 | 1.23 | 1.11 | 1.15 | 1.41 | 1.40 | 1.31 | 0.61 | 0.77 | 0.76 | 1.03 | 1.01 | 0.86 | 1.14 | 0.95 | 0.87 | 0.82 | 0.79 | 0.77 |
taurine | ME538734 | 0.97 | 0.77 | 0.78 | 1.33 | 1.22 | 1.08 | 0.85 | 0.86 | 0.68 | 1.39 | 1.38 | 1.04 | 1.10 | 0.87 | 0.76 | 1.02 | 0.99 | 0.90 |
NADP | ME538704 | 0.98 | 0.82 | 0.89 | 0.90 | 1.05 | 0.83 | 0.70 | 1.13 | 0.77 | 0.76 | 1.51 | 1.57 | 0.65 | 1.73 | 1.07 | 0.78 | 0.97 | 0.91 |
glucose 6-phosphate | ME538662 | 1.36 | 0.88 | 0.67 | 1.12 | 1.05 | 0.86 | 0.71 | 1.02 | 0.85 | 0.95 | 1.10 | 1.41 | 0.79 | 1.17 | 1.03 | 1.29 | 1.01 | 0.73 |
fructose 6-phosphate | ME538652 | 1.05 | 0.78 | 0.63 | 0.84 | 0.90 | 0.70 | 0.93 | 1.00 | 0.98 | 1.40 | 1.53 | 1.51 | 1.06 | 1.30 | 1.04 | 1.03 | 0.81 | 0.53 |
NAD | ME538702 | 0.89 | 0.78 | 0.91 | 0.93 | 0.92 | 0.85 | 1.19 | 1.16 | 1.09 | 1.17 | 1.27 | 1.20 | 1.10 | 0.99 | 1.01 | 0.88 | 0.84 | 0.82 |
dihydroxyacetone phosphate | ME538650 | 0.68 | 0.53 | 1.07 | 0.61 | 0.51 | 0.68 | 1.17 | 1.35 | 1.58 | 0.48 | 0.92 | 0.72 | 1.31 | 0.91 | 1.16 | 1.37 | 1.26 | 1.70 |
pentose phosphate | ME538711 | 0.78 | 0.62 | 0.88 | 0.67 | 0.77 | 0.83 | 0.78 | 1.27 | 1.54 | 0.70 | 1.02 | 0.91 | 1.43 | 1.18 | 1.16 | 1.11 | 1.03 | 1.30 |
ADP | ME538603 | 0.81 | 0.83 | 1.03 | 0.88 | 1.03 | 0.84 | 1.04 | 1.37 | 1.23 | 0.59 | 0.95 | 1.00 | 0.82 | 1.68 | 0.92 | 0.77 | 0.95 | 1.27 |
AMP | ME538605 | 0.82 | 0.85 | 1.01 | 0.95 | 1.11 | 0.93 | 1.02 | 1.31 | 1.21 | 0.68 | 1.02 | 1.09 | 0.85 | 1.14 | 0.97 | 0.83 | 1.00 | 1.22 |
GDP | ME538656 | 0.89 | 0.80 | 1.11 | 0.91 | 1.08 | 0.67 | 0.77 | 1.48 | 0.97 | 0.41 | 1.19 | 1.21 | 0.69 | 1.50 | 0.92 | 0.67 | 1.12 | 1.61 |
GMP | ME538678 | 0.91 | 0.76 | 0.98 | 0.97 | 1.07 | 0.65 | 1.03 | 1.45 | 0.98 | 0.48 | 1.25 | 1.12 | 0.92 | 0.98 | 0.83 | 0.86 | 1.20 | 1.55 |
UDP-glucose | ME538740 | 0.75 | 0.74 | 0.73 | 1.00 | 0.95 | 0.85 | 1.39 | 1.53 | 1.39 | 0.64 | 0.87 | 0.77 | 0.89 | 0.96 | 0.93 | 1.23 | 1.34 | 1.03 |
Creatinine | ME538642 | 1.03 | 0.58 | 1.01 | 0.95 | 0.88 | 0.87 | 1.16 | 1.39 | 1.32 | 0.79 | 1.17 | 0.96 | 0.88 | 0.91 | 0.91 | 1.02 | 1.19 | 0.98 |
UMP | ME538741 | 0.79 | 0.91 | 0.82 | 1.09 | 1.07 | 0.76 | 1.15 | 1.24 | 1.04 | 0.75 | 1.09 | 0.92 | 0.83 | 1.16 | 0.99 | 1.16 | 1.19 | 1.04 |
2/3-phosphoglycerate | ME538590 | 1.27 | 0.95 | 1.26 | 1.02 | 0.84 | 1.00 | 0.89 | 1.19 | 1.18 | 0.75 | 1.16 | 0.71 | 1.04 | 0.95 | 0.77 | 1.10 | 1.08 | 0.83 |
uric acid | ME538742 | 1.29 | 0.89 | 1.09 | 0.93 | 0.81 | 0.77 | 1.23 | 1.57 | 1.09 | 0.48 | 0.98 | 0.55 | 0.90 | 1.10 | 0.87 | 1.23 | 1.25 | 0.97 |
xanthine | ME538745 | 1.02 | 0.68 | 0.73 | 0.62 | 0.68 | 0.57 | 0.87 | 1.53 | 1.18 | 1.00 | 1.72 | 1.21 | 0.65 | 1.04 | 0.73 | 1.16 | 1.63 | 0.97 |
arginine | ME538606 | 1.03 | 0.61 | 0.92 | 0.96 | 0.69 | 0.77 | 0.99 | 1.24 | 1.09 | 0.94 | 1.54 | 1.41 | 0.79 | 0.70 | 0.89 | 1.16 | 1.19 | 1.08 |
lysine | ME538691 | 0.96 | 0.60 | 0.93 | 0.97 | 0.67 | 0.78 | 1.04 | 1.28 | 1.24 | 0.85 | 1.39 | 1.32 | 0.76 | 0.71 | 0.94 | 1.17 | 1.25 | 1.15 |
lactate | ME538686 | 0.73 | 0.75 | 0.99 | 0.65 | 1.01 | 0.94 | 0.80 | 1.40 | 1.61 | 0.70 | 1.32 | 1.35 | 0.67 | 0.95 | 0.97 | 0.80 | 1.25 | 1.13 |
pyroglutamate | ME538720 | 0.65 | 0.60 | 1.01 | 0.73 | 0.65 | 0.74 | 0.94 | 1.46 | 1.79 | 0.99 | 1.01 | 1.12 | 0.73 | 0.96 | 1.38 | 0.96 | 0.98 | 1.35 |
S-(2-succinyl)cysteine | ME538722 | NA | 0.11 | 0.11 | 0.34 | 0.26 | 0.24 | 1.33 | 0.76 | 1.07 | 0.12 | 0.23 | 0.22 | 0.33 | NA | 0.09 | 2.68 | 2.16 | 1.88 |
orotate | ME538708 | 1.10 | 0.24 | 0.50 | 0.96 | 0.47 | 0.72 | 2.29 | 1.02 | 2.15 | 0.56 | 0.40 | 0.30 | 3.00 | 0.34 | 0.14 | 2.67 | 0.39 | 0.75 |
dihydroorotate | ME538649 | 1.39 | 0.56 | 0.54 | 1.55 | 1.04 | 1.03 | 0.66 | 0.85 | 1.30 | 1.19 | 0.31 | 0.67 | 0.85 | 0.40 | 0.26 | 3.68 | 0.71 | 1.00 |
N-carbamoylaspartate | ME538706 | 0.70 | 0.19 | 0.54 | 0.89 | 0.49 | 0.82 | 0.71 | 0.75 | 2.12 | 1.05 | 0.32 | 0.38 | 2.43 | 0.20 | 0.11 | 4.54 | 0.65 | 1.11 |
IMP | ME538683 | 0.41 | 0.18 | 0.29 | 1.39 | 0.45 | 0.24 | 0.34 | 0.60 | 0.87 | 2.20 | 1.41 | 0.58 | 2.83 | 1.51 | 0.59 | 2.28 | 1.25 | 0.48 |
SAICAR | ME538726 | 0.05 | NA | NA | 0.81 | NA | 0.05 | NA | NA | NA | 0.66 | 0.05 | NA | 1.58 | 0.28 | NA | 2.80 | 0.38 | NA |
Factors:
F1 | Cell line:786-M1A | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:10 mins |
F2 | Cell line:786-M1A | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:1 hour |
F3 | Cell line:786-M1A | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:3 hours |
F4 | Cell line:786-O | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:10 mins |
F5 | Cell line:786-O | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:1 hour |
F6 | Cell line:786-O | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:3 hours |
F7 | Cell line:HK2 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:10 mins |
F8 | Cell line:HK2 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:1 hour |
F9 | Cell line:HK2 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:3 hours |
F10 | Cell line:OSLM1B | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:10 mins |
F11 | Cell line:OSLM1B | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:1 hour |
F12 | Cell line:OSLM1B | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:3 hours |
F13 | Cell line:OSRC2 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:10 mins |
F14 | Cell line:OSRC2 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:1 hour |
F15 | Cell line:OSRC2 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:3 hours |
F16 | Cell line:RFX631 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:10 mins |
F17 | Cell line:RFX631 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:1 hour |
F18 | Cell line:RFX631 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:3 hours |