Clustering data with hclust algorithm for (Study ST002225)

(Analysis AN003634)
MetaboliteStructureF1F2F3F4F5F6F7F8F9F10F11F12F13F14F15F16F17F18
cyclic AMPME5386440.440.120.210.490.290.239.911.411.130.730.520.530.530.240.300.270.280.36
argininosuccinateME5386071.050.221.050.120.140.171.091.765.640.160.290.140.120.060.100.110.110.17
N-acetylaspartateME5386980.090.080.080.600.560.514.374.544.030.030.030.030.020.020.021.020.980.98
cystathionineME5386450.090.050.070.180.130.104.694.785.300.020.040.020.050.060.040.750.680.47
N-acetylaspartylglutamateME5386990.020.010.020.110.130.134.855.005.180.010.010.010.010.010.010.800.820.86
glycineME5386770.450.070.220.450.070.065.344.193.500.270.160.040.740.540.490.610.430.38
phosphocreatineME5387130.100.080.090.010.010.014.324.273.640.520.570.450.540.480.440.830.810.82
4-hydroxyprolineME5385980.220.080.230.250.080.115.173.212.680.550.440.400.680.440.581.130.870.86
N-acetylglutamateME5387000.620.500.400.830.640.494.353.542.330.460.420.350.560.470.310.660.590.48
carnitine C5_m+4ME5386312.681.150.103.410.950.070.181.080.24NA0.920.78NA0.860.61NA0.140.24
aconitate_m+2ME5386014.000.060.072.76NANA1.42NANA0.130.110.130.270.630.220.510.150.22
citrate_m+2ME5386364.160.04NA3.590.060.002.020.090.010.160.480.420.371.270.951.260.250.19
carnitine C3_m+0ME5386202.420.290.413.530.470.551.761.031.180.910.480.540.720.270.351.910.700.47
carnitine C3_m+1ME5386212.480.220.393.670.440.531.791.031.190.910.460.530.720.230.331.950.700.45
carnitine C5_m+3ME5386303.960.690.314.680.760.312.151.730.670.570.220.220.320.170.180.570.270.17
carnitine C5_m+0ME5386283.630.840.324.240.740.222.631.770.670.710.390.180.390.160.080.590.320.10
carnitine C5_m+1ME5386293.850.790.284.520.710.182.781.840.640.650.320.130.320.100.040.540.260.06
carnitine C2_m+2ME5386191.680.110.082.230.140.057.090.620.030.360.590.770.440.600.460.850.930.97
carnitine C2_m+0ME5386170.750.600.681.050.930.814.301.140.410.560.690.900.650.550.531.101.321.02
carnitine C2_m+1ME5386180.770.580.671.080.910.804.421.120.390.550.680.890.650.550.531.091.301.01
cysteateME5386460.220.170.800.290.220.410.270.270.230.310.361.650.290.186.591.380.523.85
oxidized glutathioneME5387090.270.250.770.450.330.370.590.740.600.260.281.070.490.463.472.191.064.35
malate_m+2ME5386940.270.490.950.400.830.710.021.321.790.240.432.110.310.563.910.620.452.44
malate_m+0ME5386920.460.481.100.620.650.820.180.771.920.540.421.440.650.453.551.040.402.52
malate_m+1ME5386930.450.471.100.620.650.820.160.781.950.530.411.450.640.443.571.040.402.53
fumarate_m+0ME5386530.480.491.080.640.670.840.160.802.080.560.421.400.680.453.421.000.402.43
fumarate_m+1ME5386540.440.471.090.640.660.840.090.772.190.560.391.430.640.413.510.980.342.54
fumarate_m+3ME5386550.440.471.090.640.660.840.090.772.190.560.391.430.640.413.510.980.342.54
glutamate_m+3ME5386660.020.130.060.050.170.06NA0.07NANA0.203.82NA0.123.19NA0.070.25
proline_m+3ME538719NANA0.180.160.110.090.050.160.060.090.081.160.090.125.050.080.161.30
citrate_m+3ME5386370.610.370.060.730.110.060.870.130.03NA0.731.710.073.642.990.161.501.03
aspartate_m+3ME5386120.191.270.080.251.000.040.170.47NA0.012.162.310.011.762.950.010.661.19
malate_m+3ME5386950.211.240.050.771.030.050.181.080.06NA1.151.02NA2.512.21NA0.770.85
2-hydroxyglutarate_m+2ME5385930.610.290.161.171.000.390.190.19NA0.290.361.821.691.763.240.960.580.36
2-oxoglutarate_m+2ME5385960.600.65NA2.630.580.850.270.570.290.230.240.930.470.382.950.20NANA
carnitine C3_m+2ME5386221.410.140.212.410.250.170.890.610.250.310.920.760.310.560.600.673.793.60
carnitine C3_m+3ME5386232.250.320.163.530.390.121.320.690.060.321.210.860.310.960.810.901.762.03
NADHME5387030.270.050.150.160.08NA1.861.680.190.133.070.412.260.730.740.831.173.06
cystineME5386472.771.071.490.360.350.570.320.370.140.082.181.030.351.480.830.281.691.16
mevalonate-5-pyrophosphateME5386970.260.651.290.361.001.560.210.640.951.272.342.850.250.701.250.300.821.31
aspartate_m+2ME5386110.350.991.260.370.930.900.070.931.200.611.323.330.340.772.660.250.631.09
glutamate_m+2ME5386650.590.920.850.700.930.700.491.110.850.471.262.430.561.262.700.410.771.01
inosineME5386840.830.320.271.380.500.390.620.780.671.792.112.401.531.290.921.360.660.18
succinate_m+2ME5387320.550.480.60NANA0.530.600.970.640.661.301.140.731.072.37NA0.61NA
glucose 1-phosphateME5386610.310.290.420.340.390.311.421.261.321.631.771.552.021.721.990.390.440.42
succinate_m+0ME5387300.400.300.320.330.320.250.340.731.021.451.851.651.982.022.160.500.770.47
succinate_m+1ME5387310.490.380.380.420.420.340.300.841.011.471.871.751.992.022.270.580.860.60
carnitine C4_m+2ME5386261.220.400.272.570.780.212.213.110.510.140.950.720.300.961.060.510.851.22
carnitine C4_m+3ME5386270.860.34NA1.870.340.201.181.62NA0.280.990.500.110.941.14NA0.321.30
2-oxoglutarate_m+0ME5385941.561.000.892.431.511.500.280.670.981.290.540.481.760.820.810.620.470.37
2-oxoglutarate_m+1ME5385951.601.010.882.481.531.520.260.640.971.310.510.471.780.820.830.590.450.34
ketoleucine+ketoisoleucine_m+6ME5386851.350.330.872.120.710.901.651.692.150.510.180.301.080.410.611.240.861.03
carnitine C4_m+0ME5386240.970.560.761.940.990.881.792.382.420.480.520.450.580.390.440.940.680.81
carnitine C4_m+1ME5386250.970.550.751.960.980.871.822.412.450.460.520.440.570.390.440.940.670.81
gluconateME5386590.330.240.280.540.450.402.272.192.330.480.580.560.752.550.631.311.150.96
betaineME5386150.560.430.530.960.840.742.692.842.590.710.810.660.430.420.390.870.820.71
serineME5387280.390.180.420.420.170.223.302.613.010.740.780.630.940.850.820.840.740.93
asparagineME5386080.540.230.470.550.260.262.542.482.611.090.860.681.150.820.881.010.740.82
alanineME5386040.600.460.640.670.580.572.751.992.550.740.730.670.860.720.800.910.800.97
threonineME5387350.450.220.570.480.270.322.982.072.640.750.840.780.970.770.980.970.821.10
ornithineME5387070.360.530.730.560.230.572.101.722.620.540.590.860.830.910.781.471.211.39
UDP-GlcNacME5387390.420.450.840.420.650.681.882.232.290.810.870.870.730.611.041.060.901.26
glutamine_m+2ME5386690.370.140.280.170.130.081.522.192.970.691.100.411.630.911.120.861.021.08
glutamine_m+0ME5386670.670.230.680.590.210.301.411.682.270.921.120.781.471.011.181.091.131.24
glutamine_m+1ME5386680.670.280.670.610.270.341.371.662.300.921.110.781.470.991.181.071.101.20
4-hydroxyphenyllactateME5385970.760.400.351.180.400.322.741.520.631.010.930.671.570.940.791.811.160.82
sedoheptulose 7-phosphateME5387270.750.580.620.610.600.411.651.381.490.340.590.152.141.821.431.191.310.94
S-lactoylglutathioneME5387290.620.360.221.811.280.701.091.070.860.690.630.401.060.660.342.412.041.75
glycerylphosphorylcholineME5386761.040.971.430.590.560.592.001.802.060.330.280.510.430.390.681.461.421.46
S-SuccinylglutathioneME5387230.530.450.550.990.950.852.172.202.110.310.370.340.560.420.411.681.631.49
CMPME5386390.680.820.771.031.240.911.241.641.610.210.610.840.500.830.541.321.581.64
glutathione reduced_m+3ME5386730.350.330.710.970.920.971.241.261.380.470.630.630.720.590.702.002.032.04
glutathione reduced_m+0ME5386700.560.520.770.980.980.981.131.241.440.630.720.730.840.730.591.741.731.68
glutathione reduced_m+1ME5386710.540.510.760.980.970.981.141.241.450.620.710.720.830.720.591.761.761.70
glutathione reduced_m+2ME5386720.530.500.780.980.970.971.141.251.460.610.720.740.820.720.601.741.771.72
proline_m+2ME5387180.520.510.770.690.670.601.391.701.590.340.330.690.931.031.761.271.421.80
proline_m+0ME5387160.620.460.740.790.630.601.731.781.860.430.410.391.141.000.881.581.511.46
proline_m+1ME5387170.620.460.740.790.630.601.721.781.870.430.400.391.141.000.881.571.501.46
adenosineME5386020.820.811.341.041.642.011.201.041.570.490.570.741.160.881.030.340.520.80
aconitate_m+0ME5385991.370.940.681.100.880.630.780.580.311.691.000.881.931.230.921.211.110.76
aconitate_m+1ME5386001.500.930.611.200.870.580.800.530.211.740.960.862.011.250.891.211.100.74
2-hydroxyglutarate_m+0ME5385911.130.960.771.441.180.960.460.470.650.910.930.831.691.521.021.390.970.72
2-hydroxyglutarate_m+1ME5385921.140.940.761.471.180.960.430.440.630.920.930.831.711.531.051.400.960.71
citrate_m+0ME5386341.080.880.770.920.780.710.800.860.621.140.980.881.532.150.951.071.020.88
citrate_m+1ME5386351.130.870.750.950.770.690.820.840.611.140.970.871.542.160.961.071.020.86
hypotaurineME5386810.690.550.421.451.450.951.251.110.791.811.581.030.860.620.381.071.210.58
CDPME5386330.940.810.920.991.080.570.981.671.060.340.820.730.691.390.831.141.461.59
dTTPME5386510.961.081.020.880.930.521.061.581.320.270.640.410.691.430.641.471.361.75
GTPME5386790.900.780.850.931.110.510.651.540.790.371.181.040.702.730.740.701.071.41
UTPME5387431.010.830.731.231.130.560.851.480.900.510.970.720.732.460.810.961.111.03
CTPME5386430.910.750.800.951.050.460.871.761.000.300.760.610.612.300.761.141.411.56
ATPME5386130.810.780.860.931.120.660.871.651.160.471.000.940.682.020.760.781.071.43
UDPME5387380.940.830.791.151.090.691.011.471.000.580.980.810.811.760.851.011.161.04
glucoseME5386601.650.871.040.910.650.670.961.520.780.641.510.760.741.140.781.041.610.76
hypoxanthineME5386821.600.620.791.250.470.481.091.650.570.701.781.130.841.460.840.891.340.50
carnitine C5_m+5ME5386321.501.150.421.871.170.361.061.670.640.881.240.681.071.310.660.611.210.51
NADPHME5387051.381.120.831.371.210.521.081.220.600.681.410.761.141.580.670.800.900.73
leucine+isoleucine_m+0ME5386870.570.561.760.670.580.661.591.151.221.541.011.091.251.050.840.860.750.85
leucine+isoleucine_m+1ME5386880.480.422.030.520.450.571.541.051.191.811.001.211.411.120.880.840.640.84
aspartate_m+0ME5386090.760.921.410.711.031.260.310.831.901.301.501.450.760.801.030.590.620.83
aspartate_m+1ME5386100.750.921.410.701.031.260.300.831.901.301.501.480.750.791.050.580.610.82
carnitineME5386160.750.700.801.321.391.280.621.181.191.721.761.490.820.690.690.560.530.53
pyruvateME5387211.400.760.861.121.241.150.791.541.461.051.571.200.770.730.660.560.640.49
deoxycarnitineME5386480.640.590.661.231.191.101.751.701.711.161.141.030.610.520.550.840.800.77
beta-alanineME5386140.980.900.840.910.920.761.941.841.591.101.060.860.950.830.690.660.590.59
S-adenosylhomocysteineME5387240.720.510.750.960.960.901.661.661.730.760.900.931.080.900.790.860.901.02
citrullineME5386380.980.390.851.190.400.491.501.171.091.171.061.031.251.021.051.310.901.15
glycerol 3-phosphateME5386750.590.620.830.590.540.521.661.231.340.961.271.211.571.141.290.950.681.00
methionineME5386960.790.370.810.710.380.451.901.972.161.131.411.120.720.710.540.931.010.89
phosphorylcholineME5387150.400.390.610.560.680.771.611.751.891.271.381.390.890.760.870.900.920.96
valineME5387440.900.460.960.790.550.621.461.421.461.181.411.250.750.730.781.031.061.20
leucine+isoleucine_m+5ME5386890.830.380.870.700.450.531.291.391.611.141.451.410.740.710.941.061.111.40
leucine+isoleucine_m+6ME5386900.830.410.860.710.460.551.311.401.591.131.421.380.740.720.941.061.101.38
histidineME5386800.690.380.770.600.390.481.581.441.551.251.471.420.860.870.931.011.071.25
tyrosineME5387370.710.370.830.710.450.531.661.441.821.241.371.350.820.680.850.990.971.24
phenylalanineME5387120.770.350.920.690.450.541.481.451.641.141.381.320.820.760.911.021.021.33
tryptophanME5387360.740.370.930.710.460.551.531.451.671.161.371.350.850.700.890.990.971.32
CMP-acetylneuraminateME5386400.640.580.800.760.840.821.651.391.570.881.040.960.820.710.841.301.171.25
GDP fucoseME5386570.680.540.730.900.800.721.531.371.450.971.111.390.920.710.901.080.831.35
GDP-glucoseME5386581.220.620.961.390.910.821.010.840.980.600.720.631.610.790.891.331.231.45
phosphoenolpyruvateME5387141.491.271.411.211.001.150.821.091.440.750.780.551.090.770.621.110.970.48
glutamate_m+0ME5386631.000.851.141.041.021.080.671.171.550.980.920.961.160.871.100.860.760.86
glutamate_m+1ME5386641.000.861.141.041.021.080.671.171.540.970.920.971.160.871.130.860.760.86
N-acetylneuraminic acidME5387011.401.051.491.041.041.191.081.011.240.751.030.941.090.900.930.600.600.61
pantothenateME5387100.860.881.161.041.211.301.081.111.270.860.930.911.301.041.230.580.580.68
S-adenosylmethionineME5387251.200.841.290.971.281.280.981.111.180.740.850.751.051.091.010.790.790.79
glyceraldehyde 3-phosphateME5386740.570.570.770.991.161.291.160.931.160.951.351.231.160.830.950.950.791.19
creatineME5386411.231.111.151.411.401.310.610.770.761.031.010.861.140.950.870.820.790.77
taurineME5387340.970.770.781.331.221.080.850.860.681.391.381.041.100.870.761.020.990.90
NADPME5387040.980.820.890.901.050.830.701.130.770.761.511.570.651.731.070.780.970.91
glucose 6-phosphateME5386621.360.880.671.121.050.860.711.020.850.951.101.410.791.171.031.291.010.73
fructose 6-phosphateME5386521.050.780.630.840.900.700.931.000.981.401.531.511.061.301.041.030.810.53
NADME5387020.890.780.910.930.920.851.191.161.091.171.271.201.100.991.010.880.840.82
dihydroxyacetone phosphateME5386500.680.531.070.610.510.681.171.351.580.480.920.721.310.911.161.371.261.70
pentose phosphateME5387110.780.620.880.670.770.830.781.271.540.701.020.911.431.181.161.111.031.30
ADPME5386030.810.831.030.881.030.841.041.371.230.590.951.000.821.680.920.770.951.27
AMPME5386050.820.851.010.951.110.931.021.311.210.681.021.090.851.140.970.831.001.22
GDPME5386560.890.801.110.911.080.670.771.480.970.411.191.210.691.500.920.671.121.61
GMPME5386780.910.760.980.971.070.651.031.450.980.481.251.120.920.980.830.861.201.55
UDP-glucoseME5387400.750.740.731.000.950.851.391.531.390.640.870.770.890.960.931.231.341.03
CreatinineME5386421.030.581.010.950.880.871.161.391.320.791.170.960.880.910.911.021.190.98
UMPME5387410.790.910.821.091.070.761.151.241.040.751.090.920.831.160.991.161.191.04
2/3-phosphoglycerateME5385901.270.951.261.020.841.000.891.191.180.751.160.711.040.950.771.101.080.83
uric acidME5387421.290.891.090.930.810.771.231.571.090.480.980.550.901.100.871.231.250.97
xanthineME5387451.020.680.730.620.680.570.871.531.181.001.721.210.651.040.731.161.630.97
arginineME5386061.030.610.920.960.690.770.991.241.090.941.541.410.790.700.891.161.191.08
lysineME5386910.960.600.930.970.670.781.041.281.240.851.391.320.760.710.941.171.251.15
lactateME5386860.730.750.990.651.010.940.801.401.610.701.321.350.670.950.970.801.251.13
pyroglutamateME5387200.650.601.010.730.650.740.941.461.790.991.011.120.730.961.380.960.981.35
S-(2-succinyl)cysteineME538722NA0.110.110.340.260.241.330.761.070.120.230.220.33NA0.092.682.161.88
orotateME5387081.100.240.500.960.470.722.291.022.150.560.400.303.000.340.142.670.390.75
dihydroorotateME5386491.390.560.541.551.041.030.660.851.301.190.310.670.850.400.263.680.711.00
N-carbamoylaspartateME5387060.700.190.540.890.490.820.710.752.121.050.320.382.430.200.114.540.651.11
IMPME5386830.410.180.291.390.450.240.340.600.872.201.410.582.831.510.592.281.250.48
SAICARME5387260.05NANA0.81NA0.05NANANA0.660.05NA1.580.28NA2.800.38NA

Factors:

F1Cell line:786-M1A | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:10 mins
F2Cell line:786-M1A | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:1 hour
F3Cell line:786-M1A | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:3 hours
F4Cell line:786-O | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:10 mins
F5Cell line:786-O | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:1 hour
F6Cell line:786-O | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:3 hours
F7Cell line:HK2 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:10 mins
F8Cell line:HK2 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:1 hour
F9Cell line:HK2 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:3 hours
F10Cell line:OSLM1B | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:10 mins
F11Cell line:OSLM1B | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:1 hour
F12Cell line:OSLM1B | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:3 hours
F13Cell line:OSRC2 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:10 mins
F14Cell line:OSRC2 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:1 hour
F15Cell line:OSRC2 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:3 hours
F16Cell line:RFX631 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:10 mins
F17Cell line:RFX631 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:1 hour
F18Cell line:RFX631 | Treatment:13C6-leucine+13C6-isoleucine | Treatment duration:3 hours
Data matrix
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