Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST002375)

HILIC UNSPECIFIED ION MODE (Analysis AN003870)

Metabolite	Structure	F1	F2	F3	F4
AICAR_aminoimidazole carboxamide ribonucleotide	ME561432	3.30	0.17	0.45	0.08
3-phospho-serine	ME561412	0.06	0.15	0.38	3.41
serine	ME561379	0.20	1.27	0.47	2.06
N-acetyl-glutamate	ME561416	1.54	1.24	0.06	1.16
ribose-phosphate	ME561484	2.12	0.91	0.48	0.50
Carbamoyl phosphate	ME561465	1.16	0.47	1.23	1.14
alanine	ME561375	1.48	0.70	0.94	0.88
sarcosine	ME561445	1.47	0.73	0.94	0.86
Maltose	ME561519	0.78	0.98	1.63	0.61
trehalose-sucrose	ME561496	0.86	1.10	1.37	0.67
isocitrate	ME561479	0.92	0.94	1.26	0.89
spermidine	ME561444	0.89	0.86	1.46	0.79
2-hydroxygluterate	ME561516	0.65	0.99	1.00	1.36
Phenyllactic acid	ME561471	0.86	0.83	1.04	1.27
Glycerophosphocholine	ME561423	0.47	1.09	1.21	1.23
Phosphorylcholine	ME561411	0.41	0.96	1.24	1.39
sn-glycerol-3-phosphate	ME561472	0.52	0.98	1.19	1.32
inosine	ME561489	0.68	0.64	1.28	1.41
myo-inositol	ME561475	0.72	0.80	1.18	1.31
Acetylcarnitine DL	ME561418	0.59	0.81	1.28	1.32
tryptophan	ME561419	0.58	0.89	1.24	1.29
adenine	ME561395	0.54	1.47	0.74	1.25
deoxyuridine	ME561483	0.63	1.44	0.70	1.24
guanosine 5-diphosphate,3-diphosphate	ME561511	1.06	1.39	0.70	0.85
2-Aminooctanoic acid	ME561403	1.22	1.28	0.75	0.76
cyclic-AMP	ME561494	1.16	1.33	0.71	0.80
uridine	ME561486	1.24	0.99	0.73	1.04
UTP_neg	ME561505	1.34	1.03	0.77	0.86
UDP-D-glucose	ME561510	1.25	1.07	0.81	0.87
UDP_neg	ME561498	1.25	1.07	0.78	0.91
lactate	ME561453	0.82	1.48	0.85	0.85
S-adenosyl-L-homoCysteine_pos	ME561436	0.78	1.52	0.66	1.05
S-methyl-5-thioadenosine	ME561427	0.82	1.42	0.68	1.08
CTP_neg	ME561504	1.06	1.13	0.75	1.05
UMP	ME561430	1.00	1.25	0.72	1.03
Ng,NG-dimethyl-L-arginine	ME561417	0.92	1.20	0.85	1.03
ornithine	ME561392	0.91	1.26	0.81	1.03
NAD+_pos	ME561439	0.84	1.31	0.88	0.98
acetyl-CoA_pos	ME561443	0.85	1.25	0.90	1.00
NAD+_neg	ME561514	0.89	1.25	0.89	0.97
1-Methyl-Histidine	ME561407	0.86	1.32	0.74	1.09
pantothenate	ME561482	0.86	1.33	0.74	1.06
nicotinamide	ME561387	0.82	1.42	0.79	0.98
S-adenosyl-L-homocysteine_neg	ME561497	0.81	1.34	0.83	1.02
thymine	ME561388	1.03	0.96	0.85	1.16
shikimate	ME561473	1.00	0.99	0.94	1.07
glycine	ME561374	0.99	1.02	0.91	1.09
lysine	ME561397	1.02	1.00	0.90	1.08
arginine	ME561408	1.05	1.02	0.83	1.10
2,3-Diphosphoglyceric acid	ME561488	0.99	1.06	0.85	1.10
S-adenosyl-L-methionine	ME561437	1.01	1.04	0.83	1.12
N-acetyl-glucosamine	ME561420	1.05	1.08	0.87	1.00
p-hydroxybenzoate	ME561464	1.03	1.09	0.83	1.05
Thiamine pyrophosphate	ME561499	1.01	1.08	0.86	1.04
N-acetyl-glutamine	ME561415	0.81	1.16	0.90	1.13
O-acetyl-L-serine	ME561399	0.80	1.17	0.94	1.10
allantoin	ME561470	0.85	1.14	0.93	1.07
leucine-isoleucine	ME561391	0.84	1.14	0.95	1.08
deoxyribose-phosphate	ME561481	0.86	1.15	0.90	1.09
NADP+_pos	ME561441	0.89	1.13	0.89	1.08
Methionine sulfoxide	ME561405	0.91	1.15	0.90	1.04
histidine	ME561402	0.87	1.16	0.92	1.05
NADP+_neg	ME561515	0.88	1.17	0.91	1.05
2-Hydroxy-2-methylbutanedioic acid	ME561468	0.92	1.16	0.84	1.09
creatine	ME561386	0.93	1.11	0.85	1.11
dAMP	ME561431	0.92	1.13	0.83	1.12
glutathione	ME561428	0.93	1.06	0.93	1.07
guanidinosuccinate	ME561447	0.94	1.04	0.94	1.07
N-Acetyl-L-alanine	ME561460	0.96	1.12	0.88	1.04
Acetyllysine	ME561414	0.93	1.10	0.90	1.06
N6-Acetyl-L-lysine	ME561413	0.93	1.10	0.91	1.06
succinate	ME561456	0.93	1.06	0.99	1.02
tyrosine	ME561410	0.96	1.05	0.98	1.00
Glucose_neg	ME561517	0.87	1.05	1.03	1.04
Methylmalonic acid	ME561457	0.93	1.02	1.02	1.03
asparagine	ME561393	0.90	1.07	0.98	1.05
taurine	ME561458	0.89	1.04	1.00	1.06
methionine	ME561401	0.92	1.02	1.00	1.06
phenylalanine	ME561406	0.91	1.03	0.99	1.06
proline	ME561382	1.03	1.11	0.93	0.93
betaine	ME561383	1.01	1.06	0.95	0.98
carnitine	ME561404	1.00	1.10	0.90	1.00
citrulline	ME561409	1.00	1.11	0.91	0.98
creatinine	ME561381	0.89	1.12	0.98	1.02
Cystine	ME561421	0.87	1.18	0.97	0.98
anthranilate	ME561462	0.91	1.17	0.96	0.95
CMP	ME561429	0.95	1.16	0.94	0.95
p-aminobenzoate	ME561463	1.09	0.87	1.03	1.02
threonine	ME561385	0.97	1.01	0.99	1.03
glycolate	ME561452	0.99	0.98	1.00	1.03
glyoxylate	ME561451	0.97	0.98	1.00	1.04
acetoacetate	ME561455	1.04	0.99	0.97	1.01
a-ketoglutarate	ME561466	1.01	1.01	0.98	1.00
3-phosphoglycerate	ME561477	1.04	1.04	0.99	0.93
FAD	ME561442	1.03	1.00	1.03	0.94
2-oxobutanoate	ME561454	1.03	0.95	1.01	1.01
cytosine	ME561380	1.05	0.94	1.02	0.99
UDP-N-acetyl-glucosamine	ME561512	1.07	0.99	0.98	0.96
Urea	ME561373	1.07	0.96	1.00	0.97
a-Ketoglutarate_PH	ME561518	1.14	0.91	0.93	1.02
cholesteryl sulfate	ME561503	1.11	1.00	0.94	0.95
N-acetyl-glucosamine-1-phosphate	ME561491	0.92	0.87	1.11	1.09
glutathione_neg	ME561492	0.91	0.98	0.96	1.16
valine	ME561384	0.94	0.96	0.93	1.16
IMP	ME561434	0.99	0.90	0.99	1.12
Taurodeoxycholic acid	ME561506	0.98	0.93	1.02	1.07
L-Cys-Gly	ME561450	0.78	1.04	0.80	1.38
4-aminobutyrate	ME561377	0.81	1.07	0.88	1.24
xanthine	ME561469	0.77	1.14	0.88	1.21
cytidine	ME561422	0.92	1.13	0.75	1.19
citrate	ME561480	0.88	1.09	0.78	1.25
citrate-isocitrate	ME561478	0.84	1.12	0.81	1.23
hydroxyphenylpyruvate	ME561476	0.75	0.96	1.20	1.08
thiamine	ME561424	0.82	0.98	1.12	1.08
glutamine	ME561398	0.81	1.02	1.05	1.12
Phenylpropiolic acid	ME561467	0.82	1.01	1.06	1.11
AMP	ME561433	0.82	1.09	0.98	1.10
hydroxyproline	ME561390	0.82	1.08	0.97	1.13
aconitate	ME561474	0.82	1.08	0.93	1.16
1-pyrroline-5-carboxylate(P5C)	ME561446	0.81	1.05	0.97	1.17
Itaconate_pos	ME561448	0.79	1.06	0.99	1.16
ATP_neg	ME561507	0.75	1.15	1.01	1.09
dGTP	ME561508	0.76	1.08	1.05	1.11
dGDP_neg	ME561501	0.73	1.13	0.98	1.16
glutathione disulfide_neg	ME561513	0.74	1.09	1.00	1.16
glutathione disulfide_pos	ME561438	0.74	1.09	1.02	1.15
adenosine	ME561425	0.60	1.13	1.10	1.17
GMP	ME561435	0.64	1.15	1.06	1.14
IDP_neg	ME561502	0.67	1.15	1.01	1.17
DL-Pipecolic acid	ME561389	0.73	1.03	1.06	1.18
glutamate	ME561400	0.66	1.01	1.07	1.26
malate	ME561461	0.73	1.17	1.08	1.02
1-Methyladenosine	ME561426	0.62	1.32	0.98	1.08
choline	ME561376	0.71	1.24	0.93	1.12
dimethylglycine	ME561378	0.72	1.25	0.93	1.11
ADP_neg	ME561500	0.70	1.19	0.96	1.14
beta-Hydroxybutyrate	ME561449	0.71	1.21	0.94	1.14
GTP_neg	ME561509	0.76	1.23	0.95	1.06
Pyroglutamic acid	ME561459	0.82	1.22	0.93	1.02
thymidine	ME561485	0.30	1.97	0.66	1.07
fructose-1,6-bisphosphate	ME561495	0.95	2.55	0.29	0.22
D-sedoheptulose-1-7-phosphate	ME561490	0.94	2.14	0.45	0.47
NADH	ME561440	1.05	1.99	0.46	0.49
octulose-monophosphate (O8P-O1P)	ME561493	0.99	1.98	0.48	0.55
hexose-phosphate	ME561487	0.91	1.73	0.68	0.67
aspartate	ME561394	1.20	1.57	0.52	0.71
homocysteine	ME561396	1.15	1.61	0.56	0.68

Factors:

F1	Treatment:GOT1 KO_Serine-free
F2	Treatment:GOT1 KO_Serine-replete
F3	Treatment:WT_Serine-free
F4	Treatment:WT_Serine-replete

Data matrix