Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST002507)

(Analysis AN004129)

Metabolite	Structure	F1	F2	F3	F4
ADP / dGDP_13C2	ME604081	NA	0.21	2.55	0.24
CMP_13C8	ME604141	NA	0.10	2.69	0.21
aconitic acid_13C2 -	ME604070	1.91	0.20	1.24	0.30
glutathione	ME604243	1.79	0.41	1.42	0.38
glutathione_13C1	ME604244	1.80	0.41	1.44	0.36
cystathionine_13C1	ME604151	2.13	0.42	1.08	0.36
acetoacetate / succinic semialdehyde_13C4	ME604064	1.94	0.45	1.12	0.49
serine_13C3	ME604371	1.83	0.59	1.05	0.53
S-adenosyl-L-homoCysteine	ME604356	1.83	0.62	1.00	0.11
serine_13C1	ME604369	1.95	0.68	0.88	0.48
aspartate	ME604112	2.10	0.78	0.82	0.29
malate_13C1	ME604313	1.97	0.79	0.91	0.33
glutamine_13C2	ME604239	2.69	0.18	0.69	0.44
serine_13C2	ME604370	2.50	0.21	0.77	0.53
glutamate_13C2	ME604233	2.63	0.10	0.53	0.73
UTP_13C5	ME604390	2.41	0.21	0.64	0.74
choline+	ME604124	2.64	0.53	0.61	0.22
choline_13C1+	ME604125	2.74	0.52	0.59	0.15
malate_13C4	ME604316	2.35	0.97	0.43	0.26
malate_13C3	ME604315	2.25	0.57	0.81	0.37
UDP-N-acetyl-galactosamine/glucosamine	ME604379	2.36	0.84	0.61	0.20
glycerol-2/3-phosphate	ME604259	2.39	0.68	0.57	0.36
aspartate_13C1	ME604113	2.37	0.65	0.71	0.27
aspartate_13C3	ME604115	2.37	0.65	0.71	0.27
glutamate_13C5	ME604236	2.33	NA	0.21	0.45
glutathione_13C3	ME604246	2.18	0.16	0.24	NA
ATP / dGTP_13C6	ME604120	2.27	NA	0.09	0.18
UDP-N-acetyl-galactosamine/glucosamine_13C6	ME604381	2.33	0.01	0.16	NA
CTP_13C6	ME604146	2.64	0.08	NA	0.28
CTP_13C7	ME604147	2.43	0.46	NA	0.11
aspartate_13C2	ME604114	3.39	0.03	0.32	0.26
N-carbamoyl-L-aspartate	ME604331	3.38	0.22	0.30	0.10
citrate(iso)/citrate_13C1	ME604131	3.27	0.35	NA	0.52
ADP / dGDP_13C5	ME604084	2.68	0.05	0.23	0.56
xylitol / arabitol / ribito_13C5	ME604396	2.86	0.07	0.31	0.77
2-HG_13C2	ME604041	3.09	0.04	0.18	0.69
2-HG_13C3	ME604042	3.17	0.10	0.17	0.56
glutamate_13C4	ME604235	2.96	0.02	0.15	0.39
glutamate_13C3	ME604234	3.04	0.08	0.34	0.53
malate_13C2	ME604314	3.11	0.07	0.46	0.36
CTP_13C5	ME604145	2.36	0.05	0.36	1.23
succinate_13C3	ME604377	2.39	0.15	0.36	1.10
S-adenosyl-L-methionine_13C5	ME604363	1.94	0.12	0.23	1.27
a-KG_13C4	ME604099	2.06	0.03	0.14	1.29
S-adenosyl-L-methionine_13C6	ME604364	2.16	0.01	0.13	1.20
guanosine_13C5	ME604281	1.19	0.49	0.65	1.67
glycerate_13C2	ME604257	1.39	0.25	0.85	1.51
glycerate_13C3	ME604258	1.27	0.41	0.87	1.45
deoxyguanosine_13C5	ME604171	1.60	0.12	0.25	1.21
GTP_13C6	ME604275	1.77	0.07	0.43	1.27
succinate_13C2	ME604376	1.60	0.17	0.72	1.51
GTP_13C5	ME604274	1.61	0.36	0.68	1.35
sorbitol / galactitol / L-iditol / manitol_13C6	ME604373	1.79	0.26	0.55	1.40
a-KG_13C3	ME604098	1.98	0.13	0.32	1.57
a-KG_13C5	ME604100	1.87	0.11	0.30	1.72
a-KG_13C2	ME604097	1.66	0.15	0.43	1.76
citrate(iso)/citrate_13C2	ME604132	1.44	0.23	0.41	1.92
adenosine_13C5	ME604073	1.43	NA	0.07	1.03
GTP_13C7	ME604276	1.45	0.26	NA	0.92
ATP / dGTP_13C7	ME604121	1.11	NA	NA	0.78
citrate(iso)/citrate_13C3	ME604133	1.37	NA	NA	0.63
S-adenosyl-L-methionine_13C7	ME604365	1.51	NA	NA	0.49
ATP / dGTP_13C5	ME604119	2.04	0.26	0.49	0.84
fumarate_13C2	ME604219	1.74	NA	0.50	0.51
S-adenosyl-L-methionine_13C4	ME604362	2.05	0.03	0.11	0.88
guanosine_13C6	ME604282	1.70	NA	0.19	0.70
S-adenosyl-L-methionine_13C3	ME604361	1.89	NA	0.12	0.55
UTP_13C7	ME604392	1.28	NA	0.72	NA
D-galactosamine/glucosamine-1/6-phosphate	ME604176	1.59	0.51	0.31	NA
aspartate_13C4	ME604116	1.85	NA	0.23	0.07
N-carbamoyl-L-aspartate_13C1	ME604332	1.87	0.06	0.20	NA
2-HG_13C4	ME604043	1.41	NA	NA	0.18
glutamine_13C4	ME604241	1.47	NA	0.07	NA
N-carbamoyl-L-aspartate_13C2	ME604333	1.50	NA	0.01	NA
N-carbamoyl-L-aspartate_13C3	ME604334	1.49	NA	0.03	NA
UDP-N-acetyl-galactosamine/glucosamine_13C8	ME604382	1.48	NA	0.04	NA
6-phospho-D-gluconate_13C1	ME604054	NA	NA	0.66	1.34
6-phospho-D-gluconate_13C5	ME604058	NA	0.01	NA	1.50
UMP_13C5	ME604384	0.62	NA	NA	1.38
IMP_13C10	ME604294	NA	0.77	0.24	1.49
6-phospho-D-gluconate_13C6	ME604059	0.44	0.51	0.86	1.94
GAP / DHAP_13C3	ME604181	0.16	1.21	0.70	1.93
acetyl-CoA +	ME604065	0.35	1.65	NA	NA
guanosine_13C8	ME604284	0.41	2.17	NA	NA
acetoacetate / succinic semialdehyde_13C3	ME604063	0.64	2.03	0.63	1.21
GAP / DHAP	ME604178	0.70	2.08	0.74	0.79
pyruvate	ME604352	0.33	2.48	0.92	0.27
F6P/G1P/G6P	ME604222	0.20	1.92	1.25	0.62
N-acetyl-glucosamine-1/6-phosphate	ME604324	NA	2.10	0.33	0.57
F-1,6/2,6-P_13C2	ME604211	NA	1.93	0.67	0.39
phosphoenolpyruvate_13C3	ME604345	NA	1.91	0.81	0.64
aconitic acid_13C1 -	ME604069	1.28	0.85	1.60	0.15
D-ribose-1/5-phosphate	ME604182	1.10	0.56	1.34	NA
S-adenosyl-L-homoCysteine_13C1	ME604357	1.26	0.21	1.27	NA
6-phospho-D-gluconate	ME604053	NA	0.52	1.24	NA
D-ribose-1/5-phosphate_13C4	ME604186	0.56	NA	1.44	NA
D-sedoheptulose-7-phosphate_13C7	ME604195	0.42	NA	1.49	1.09
D-sedoheptulose-7-phosphate	ME604188	0.39	0.85	1.51	1.26
glutathione disulfide	ME604249	0.54	0.64	1.68	1.13
D-ribose-1/5-phosphate_13C5	ME604187	0.84	1.15	NA	1.02
UMP	ME604383	1.32	1.59	0.31	0.78
oxaloacetate	ME604337	0.82	1.42	0.95	NA
ADP / dGDP_13C1	ME604079	1.03	1.35	1.15	0.47
NAD+	ME604327	1.16	1.18	1.17	0.49
aconitic acid -	ME604068	1.24	1.40	1.13	0.23
D-ribose-1/5-phosphate_13C3	ME604185	1.14	1.16	1.08	0.25
pyruvate_13C1	ME604353	0.79	1.42	1.46	0.33
UTP	ME604389	0.77	1.32	1.29	0.62
2-HG	ME604039	1.20	1.00	1.07	0.73
glutamine_13C3	ME604240	1.23	1.14	1.01	0.69
2,3-diphosphoglycerate	ME604035	1.43	1.34	0.66	0.78
acetoacetate / succinic semialdehyde_13C1	ME604061	1.36	1.46	0.66	0.75
UTP_13C6	ME604391	1.11	1.23	0.61	0.70
dCTP	ME604163	1.31	1.07	0.73	0.85
glutathione_13C2	ME604245	1.24	1.20	0.81	0.76
glutamate_13C1	ME604232	1.62	0.81	0.93	0.64
2-HG_13C1	ME604040	1.34	0.92	1.02	0.72
glutamate	ME604231	1.46	0.89	0.99	0.66
glutamine	ME604237	1.74	0.97	0.91	0.38
malate	ME604312	1.71	0.89	1.04	0.36
acetoacetic acid / succinic semialdehyde	ME604060	1.46	1.04	0.91	0.59
AMP / dGMP	ME604105	1.59	1.03	0.96	0.43
serine	ME604368	1.57	0.96	0.96	0.51
acetoacetate / succinic semialdehyde_13C2	ME604062	1.73	0.94	0.60	0.50
2/3-phosphoglycerate	ME604045	1.73	1.01	0.68	0.15
glutamine_13C1	ME604238	1.67	1.26	0.75	0.32
glycine_13C2	ME604264	1.38	0.45	0.97	1.20
alanine_13C2	ME604103	1.30	0.63	0.81	1.26
S-adenosyl-L-methionine_13C2	ME604360	1.15	0.67	0.85	1.33
fumarate_13C3	ME604220	1.52	0.69	0.81	0.98
fumarate_13C1	ME604218	1.29	0.97	0.80	0.95
pyruvate_13C2	ME604354	1.37	0.88	0.70	1.05
deoxyguanosine	ME604169	1.27	0.86	0.85	1.01
citrate(iso)/citrate	ME604130	1.28	0.88	0.79	1.05
pyruvate_13C3	ME604355	1.30	0.89	0.74	1.07
alanine_13C3	ME604104	1.09	0.76	0.95	1.19
cystathionine	ME604150	1.21	0.81	0.91	1.07
itaconic acid	ME604300	1.30	0.70	0.98	1.02
lactate	ME604303	0.77	1.06	0.98	1.19
F-1,6/2,6-P_13C6	ME604215	0.75	0.90	1.00	1.34
lactate_13C1	ME604304	0.84	0.99	0.94	1.23
S-adenosyl-L-methionine	ME604358	0.81	0.92	1.02	1.26
S-adenosyl-L-methionine_13C1	ME604359	0.84	0.91	0.97	1.27
guanosine	ME604279	0.95	0.88	0.98	1.19
Total Ion Count	ME604030	0.93	1.01	0.99	1.06
lactate_13C2	ME604305	0.89	0.81	0.82	1.48
lactate_13C3	ME604306	0.88	0.85	0.81	1.45
a-KG	ME604095	0.94	1.00	0.78	1.28
a-KG_13C1	ME604096	1.03	0.93	0.73	1.32
CMP	ME604137	0.96	0.91	1.37	0.80
succinate_13C4	ME604378	0.88	0.94	1.48	0.70
NADH	ME604328	0.89	1.41	0.96	0.74
ADP / dGDP	ME604078	1.01	1.25	0.93	0.81
glycerol-2/3-phosphate_13C3	ME604261	0.92	1.14	0.93	1.01
alanine_13C1	ME604102	0.97	1.23	0.84	0.96
fumarate	ME604217	0.99	1.15	0.88	0.97
leucine / leucine(iso)_13C1	ME604308	0.72	1.16	1.12	1.01
leucine / leucine(iso)	ME604307	0.71	1.15	1.11	1.03
leucine / leucine(iso)_13C2	ME604309	0.72	1.14	1.12	1.02
succinate_13C1	ME604375	0.90	1.16	1.07	0.88
xylitol / arabitol / ribito	ME604395	0.84	1.15	1.16	0.85
2/3-phosphoglycerate_13C3	ME604048	0.91	0.92	1.26	0.91
CTP	ME604144	0.79	0.95	1.27	1.00
ATP / dGTP	ME604117	0.96	0.97	1.13	0.94
glycine	ME604262	0.96	1.04	1.11	0.90
2-HG_13C5	ME604044	1.10	0.91	1.11	0.88
glycine_13C1	ME604263	1.07	0.91	1.07	0.95
fructose / mannose	ME604216	0.23	1.53	1.55	0.69
glucose_13C6	ME604230	0.14	1.47	1.43	0.96
glycerate	ME604255	0.36	1.60	1.24	0.81
sorbitol / galactitol / L-iditol / manitol	ME604372	0.35	1.45	1.32	0.88
succinate	ME604374	0.66	1.34	1.16	0.85
glycerate_13C1	ME604256	0.52	1.43	1.22	0.83
GTP	ME604272	0.54	1.37	1.30	0.80
F-1,6/2,6-P_13C1	ME604210	0.52	1.39	1.00	1.09
galactose / glucose	ME604229	0.51	1.24	1.08	1.18
F-1,6/2,6-P_13C3	ME604212	0.47	1.16	1.38	1.00
F-1,6/2,6-P_13C4	ME604213	0.48	1.16	1.14	0.95
F-1,6/2,6-P_13C5	ME604214	0.57	1.08	0.95	1.40
cysteine	ME604152	0.44	1.02	1.11	1.43
F6P/G1P/G6P_13C6	ME604228	0.35	1.00	1.22	1.43
adenosine	ME604071	0.60	1.32	0.78	1.30
cysteine_13C3	ME604155	0.73	1.19	0.76	1.41
alanine	ME604101	0.69	1.51	0.93	0.87
F-1,6/2,6-P	ME604209	0.68	1.41	0.83	1.08

Factors:

F1	Genotype:Wild-type \| Treatment:120mins
F2	Genotype:Wild-type \| Treatment:15mins
F3	Genotype:Wild-type \| Treatment:30mins
F4	Genotype:Wild-type \| Treatment:60mins

Data matrix