Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST002809)

(Analysis AN004566)

Metabolite	Structure	F1	F2	F3	F4	F5	F6
guanidinoacetate	ME726405	0.17	0.45	3.76	0.92	0.54	0.16
cysteine-glutathione disulfide	ME726358	0.11	2.78	1.98	0.40	0.58	0.15
glutathione, reduced (GSH)	ME726396	0.06	2.93	2.49	0.16	0.27	0.08
tryptophan	ME726513	1.61	3.12	0.01	0.68	0.56	0.03
carnosine	ME726349	0.19	4.64	0.43	0.29	0.29	0.17
N-acetylputrescine	ME726458	0.41	4.49	0.17	0.15	0.53	0.25
putrescine	ME726485	0.31	4.58	0.14	0.18	0.52	0.28
gamma-glutamylglutamine	ME726380	0.03	3.92	0.74	0.11	0.94	0.26
gamma-glutamylglutamate	ME726379	0.01	3.64	1.00	0.37	0.81	0.18
gamma-glutamylglycine	ME726381	0.02	3.77	0.76	0.37	0.83	0.25
cysteinylglycine	ME726359	0.06	4.06	1.34	0.16	0.29	0.09
gamma-glutamylhistidine	ME726382	0.12	3.89	0.87	0.30	0.47	0.34
glutamate, gamma-methyl ester	ME726392	0.18	3.81	1.10	0.31	0.35	0.25
gamma-glutamylalanine	ME726374	0.00	3.28	0.68	NA	NA	0.04
anserine	ME726334	0.24	3.29	0.31	NA	NA	0.16
5-(2-Hydroxyethyl)-4-methylthiazole	ME726316	0.19	3.13	0.43	NA	NA	0.25
lanthionine	ME726425	0.26	3.04	0.36	NA	NA	0.34
S-methylmethionine	ME726499	0.74	2.42	0.41	NA	NA	0.43
4-hydroxyglutamate	ME726313	0.21	2.34	0.92	NA	NA	0.53
gamma-glutamyl-alpha-lysine	ME726375	0.28	2.40	0.78	NA	NA	0.54
homoarginine	ME726408	0.30	2.33	0.79	NA	NA	0.58
1-methyl-5-imidazolelactate	ME726288	0.51	2.17	0.71	NA	NA	0.60
homocitrulline	ME726409	0.46	2.33	0.75	NA	NA	0.46
gamma-glutamylphenylalanine	ME726386	0.14	2.83	0.70	NA	NA	0.32
gamma-glutamyltyrosine	ME726389	0.10	2.82	0.78	NA	NA	0.30
sarcosine	ME726494	0.17	2.59	0.79	NA	NA	0.45
2-aminoadipate	ME726293	0.26	2.54	0.91	NA	NA	0.29
(R)-3-hydroxybutyrylcarnitine	ME726284	0.36	2.58	0.70	NA	NA	0.35
S-methylcysteine sulfoxide	ME726498	0.35	2.54	0.76	NA	NA	0.35
gamma-glutamylserine	ME726387	0.03	3.19	0.92	0.33	1.27	0.27
gamma-glutamylthreonine	ME726388	0.15	3.25	0.90	0.29	0.98	0.42
gamma-glutamylleucine	ME726384	0.25	2.83	0.90	0.38	1.11	0.53
gamma-glutamylisoleucine*	ME726383	0.32	2.57	0.98	0.35	1.20	0.58
gamma-glutamylvaline	ME726390	0.34	2.48	1.06	0.26	1.31	0.55
N,N,N-trimethyl-alanylproline betaine (TMAP)	ME726435	0.93	2.51	0.58	0.80	0.60	0.58
riboflavin (Vitamin B2)	ME726490	0.72	2.76	0.44	0.79	0.61	0.67
7-methylguanine	ME726327	0.27	2.56	0.76	0.99	0.69	0.72
creatinine	ME726355	0.53	2.35	0.78	0.93	0.64	0.77
thiamin (Vitamin B1)	ME726505	0.59	2.48	0.76	0.98	0.56	0.62
4-imidazoleacetate	ME726314	0.52	2.89	0.67	0.55	0.81	0.57
1-methyl-5-imidazoleacetate	ME726287	0.53	2.87	0.71	0.75	0.55	0.58
homostachydrine*	ME726411	0.52	2.75	0.83	0.73	0.56	0.60
hypotaurine	ME726415	0.52	2.60	0.85	0.69	0.70	0.64
N-methylproline	ME726465	0.59	2.61	0.65	0.78	0.65	0.72
spermidine	ME726500	0.49	2.76	0.68	0.72	0.67	0.68
imidazole lactate	ME726416	0.21	3.06	1.06	1.00	0.30	0.37
creatine	ME726354	0.28	3.07	0.96	0.65	0.61	0.42
deoxycarnitine	ME726365	0.38	3.06	0.77	0.63	0.59	0.58
3-aminoisobutyrate	ME726302	0.32	3.44	0.50	0.59	0.60	0.55
betaine	ME726343	0.36	3.27	0.51	0.62	0.58	0.66
glutamine_degradant*	ME726394	0.44	3.26	0.69	0.64	0.46	0.51
imidazole propionate	ME726417	0.39	3.22	0.61	0.77	0.44	0.57
inosine 5^-monophosphate (IMP)	ME726418	0.34	3.32	0.75	0.69	0.52	0.39
(N(1) + N(8))-acetylspermidine	ME726283	0.29	3.23	0.70	0.66	0.71	0.43
2-oxoarginine*	ME726300	2.41	0.35	0.41	1.00	0.60	1.23
methylphosphate	ME726433	2.15	0.72	0.68	0.84	0.78	0.82
pipecolate	ME726479	2.42	0.67	0.55	1.05	0.51	0.80
saccharopine	ME726492	0.22	1.48	2.05	NA	NA	0.25
2^-deoxyadenosine	ME726294	1.66	0.80	0.90	NA	NA	0.64
diacetylchitobiose	ME726366	1.44	0.77	0.73	NA	NA	1.07
hydroxyasparagine	ME726412	0.67	1.63	0.48	NA	NA	1.23
N-acetylproline	ME726457	1.13	1.27	0.97	NA	NA	0.63
N,N-dimethyl-pro-pro	ME726437	1.04	1.67	0.54	NA	NA	0.75
tryptamine	ME726512	1.00	1.38	0.70	NA	NA	0.92
cysteinylglycine disulfide*	ME726360	0.56	1.61	1.27	NA	NA	0.56
formiminoglutamate	ME726371	0.41	1.79	1.18	NA	NA	0.61
cadaverine	ME726346	0.78	1.66	0.78	NA	NA	0.78
carboxyethyl-GABA	ME726347	0.66	1.68	0.85	NA	NA	0.81
serotonin	ME726497	0.60	1.65	0.90	NA	NA	0.85
N-methylpipecolate	ME726464	0.80	1.36	0.98	NA	NA	0.86
1-methyladenine	ME726289	0.65	1.56	1.04	NA	NA	0.75
S-carboxymethyl-L-cysteine	ME726495	0.60	1.59	1.04	NA	NA	0.78
5-methylnorleucine	ME726324	0.70	1.54	1.12	NA	NA	0.64
N-acetylglycine	ME726452	0.68	1.43	1.14	NA	NA	0.75
3-ureidopropionate	ME726310	0.59	2.13	0.42	NA	NA	0.86
5-methylcytosine	ME726323	0.41	1.99	0.80	NA	NA	0.80
5,6-dihydrothymine	ME726318	0.64	1.95	0.65	NA	NA	0.77
3-methoxytyrosine	ME726305	0.60	1.93	0.88	NA	NA	0.60
N-acetylhistidine	ME726453	0.65	1.99	0.72	NA	NA	0.64
N4-acetylcytidine	ME726440	0.70	1.88	0.81	NA	NA	0.62
N-acetylisoleucine	ME726454	0.73	1.87	0.76	NA	NA	0.64
ectoine	ME726369	0.46	1.19	0.91	NA	NA	1.44
urea	ME726520	0.84	0.90	1.06	NA	NA	1.20
N,N-dimethyl-5-aminovalerate	ME726436	1.20	0.79	1.49	NA	NA	0.51
6-oxopiperidine-2-carboxylate	ME726326	0.76	1.16	1.26	NA	NA	0.82
gamma-glutamyl-2-aminobutyrate	ME726373	0.50	1.14	1.59	NA	NA	0.76
hexanoylcarnitine (C6)	ME726407	0.63	1.12	1.56	NA	NA	0.69
tryptophylglycine	ME726515	0.59	0.49	0.57	1.26	2.02	1.07
phenylalanylalanine	ME726474	1.10	0.74	0.67	1.18	1.43	0.88
leucylglycine	ME726428	1.35	0.43	0.90	0.96	1.33	1.03
phenylalanylglycine	ME726475	1.49	0.36	0.76	1.03	1.30	1.06
adenosine	ME726330	1.47	0.62	1.09	0.56	1.47	0.79
leucylglutamine*	ME726427	1.34	0.72	0.83	0.88	1.26	0.98
N-acetylmethionine sulfoxide	ME726456	1.25	0.82	0.83	0.68	1.47	0.94
3-phosphoglycerate	ME726308	1.43	0.01	1.36	0.51	1.73	0.96
N-acetylglucosamine/N-acetylgalactosamine	ME726448	0.97	0.18	1.53	0.84	1.36	1.12
thiamin monophosphate	ME726506	0.89	0.33	1.31	0.93	1.27	1.27
prolylhydroxyproline	ME726482	0.24	1.62	1.78	1.23	0.49	0.64
5-aminovalerate	ME726320	0.26	1.93	0.77	1.15	1.17	0.72
oxindolylalanine	ME726470	0.68	1.89	0.50	1.28	1.15	0.50
N-acetyl-isoputreanine	ME726455	0.60	1.80	0.60	0.64	1.75	0.60
fructosyllysine	ME726372	0.54	1.77	0.67	0.83	1.35	0.84
N-acetylasparagine	ME726445	0.62	1.50	0.86	0.97	1.40	0.66
N-acetylarginine	ME726444	0.95	1.93	0.48	0.75	1.03	0.86
4-guanidinobutanoate	ME726312	0.68	2.11	0.42	1.28	0.63	0.88
N6,N6-dimethyllysine	ME726442	0.49	1.91	0.55	1.04	0.93	1.08
N6,N6,N6-trimethyllysine	ME726441	0.68	2.02	0.52	0.93	0.84	0.99
tiglyl carnitine (C5)	ME726509	0.56	2.37	0.93	0.61	0.89	0.64
xanthine	ME726523	0.43	2.33	1.13	0.59	0.95	0.56
acetylcarnitine (C2)	ME726328	0.31	2.16	0.91	0.81	0.98	0.83
taurine	ME726504	0.56	2.17	0.88	0.78	0.85	0.76
S-adenosylmethionine (SAM)	ME726493	0.55	2.03	1.09	0.82	0.85	0.65
threonine	ME726508	0.47	2.18	1.04	0.85	0.78	0.69
hydroxyproline	ME726414	0.43	1.84	1.06	0.72	1.13	0.82
N2,N2-dimethylguanosine	ME726439	0.47	1.76	0.98	1.07	0.79	0.94
5-methylcytidine	ME726322	0.41	1.91	1.07	1.00	0.79	0.82
uracil	ME726518	0.58	1.90	1.05	1.04	0.68	0.75
aspartate	ME726338	0.79	1.98	0.77	0.75	0.94	0.78
benzoylcarnitine*	ME726339	0.63	1.82	1.03	0.92	0.83	0.78
pantothenate (Vitamin B5)	ME726471	0.68	1.73	1.04	0.95	0.80	0.80
carnitine	ME726348	0.71	1.76	0.91	0.73	1.03	0.86
N,N,N-trimethyl-5-aminovalerate	ME726434	0.68	1.78	1.02	0.77	0.99	0.78
cysteine	ME726357	0.62	1.98	0.96	0.83	0.79	0.81
glycine	ME726401	0.64	1.85	0.91	0.89	0.87	0.85
dimethylglycine	ME726368	0.71	1.88	0.89	0.86	0.86	0.81
glutamate	ME726391	0.69	1.91	0.91	0.85	0.84	0.80
N6-methyllysine	ME726443	0.59	1.89	0.81	0.82	0.99	0.90
5-methylthioadenosine (MTA)	ME726325	0.63	1.94	0.94	0.76	0.94	0.79
alanine	ME726331	0.53	1.97	0.93	0.79	0.98	0.79
guanine	ME726406	0.81	1.62	0.94	0.96	0.86	0.81
phosphoethanolamine (PE)	ME726478	0.90	1.69	0.83	1.01	0.79	0.77
alanylleucine	ME726332	0.78	1.51	0.98	0.90	1.14	0.69
UMP	ME726517	0.91	1.40	1.06	0.88	1.10	0.65
2^-deoxyadenosine 5^-monophosphate	ME726295	0.93	1.58	0.93	0.81	1.09	0.65
2-hydroxyglutarate	ME726297	0.82	1.68	1.05	0.82	0.99	0.63
CMP	ME726353	0.71	1.55	1.31	0.86	1.02	0.54
phosphocholine	ME726477	0.69	1.39	1.39	0.93	1.03	0.56
(S)-3-hydroxybutyrylcarnitine	ME726285	0.57	1.76	1.34	0.64	1.17	0.51
beta-alanine	ME726340	0.41	1.64	1.33	0.81	1.13	0.67
cytosine	ME726363	0.56	1.57	1.23	0.81	1.14	0.70
nicotinamide riboside	ME726462	0.76	1.39	1.13	1.20	0.85	0.67
1-methyladenosine	ME726290	0.50	1.52	1.28	1.07	0.87	0.76
cytidine	ME726362	0.54	1.73	1.24	0.97	0.85	0.68
butyrylcarnitine (C4)	ME726345	0.47	1.23	1.72	0.63	1.31	0.64
2-methylbutyrylcarnitine (C5)	ME726298	0.36	1.57	1.65	0.36	1.54	0.51
cystathionine	ME726356	0.18	1.83	1.67	0.55	1.35	0.42
gamma-glutamylmethionine	ME726385	0.02	2.49	1.47	0.73	1.13	0.17
3-methylhistidine	ME726307	0.51	2.03	1.32	0.81	0.81	0.52
isovalerylcarnitine (C5)	ME726422	0.35	1.81	1.53	0.75	1.12	0.43
isobutyrylcarnitine (C4)	ME726419	0.32	2.08	1.44	0.62	1.16	0.37
propionylcarnitine (C3)	ME726483	0.39	1.96	1.57	0.53	1.03	0.52
citrulline	ME726352	0.33	1.89	1.37	0.70	0.99	0.73
1-methylhistidine	ME726291	0.21	2.22	1.52	0.63	0.92	0.50
methionine sulfone	ME726431	0.24	2.11	1.34	0.73	0.99	0.60
phenylacetylglycine	ME726472	0.41	0.96	1.10	0.90	1.07	1.56
kynurenate	ME726423	0.23	1.08	1.73	0.94	1.05	0.98
3-formylindole	ME726303	0.26	0.99	1.43	0.71	1.45	1.17
kynurenine	ME726424	0.19	0.93	1.45	0.76	1.50	1.16
N-acetylglutamate	ME726450	0.70	1.26	1.14	0.73	1.62	0.55
N-acetylglutamine	ME726451	0.74	1.15	1.16	0.62	1.58	0.76
ornithine	ME726469	0.75	1.05	1.13	0.68	1.40	0.99
valylleucine	ME726522	0.93	1.02	0.97	0.92	1.34	0.81
beta-hydroxyisovaleroylcarnitine	ME726342	0.85	1.27	1.23	0.70	1.21	0.73
S-1-pyrroline-5-carboxylate	ME726491	0.74	1.18	1.26	0.84	1.24	0.73
3-hydroxyhexanoylcarnitine (1)	ME726304	0.87	1.12	1.14	0.77	1.35	0.75
adenine	ME726329	1.03	1.14	1.11	0.83	1.23	0.66
2^-deoxycytidine	ME726296	1.31	1.08	1.03	1.04	0.80	0.73
nicotinamide ribonucleotide (NMN)	ME726461	1.33	0.65	1.10	1.22	0.83	0.87
glycylleucine	ME726403	1.14	0.77	1.02	1.06	0.94	1.07
methionine	ME726430	1.18	0.86	0.96	1.09	0.89	1.03
5-(galactosylhydroxy)-L-lysine	ME726317	1.02	0.84	1.07	1.01	0.90	1.16
pyridoxamine	ME726487	0.95	0.78	1.10	0.92	1.01	1.24
5,6-dihydrouridine	ME726319	0.65	1.02	1.29	1.16	0.75	1.12
2^-O-methylcytidine	ME726299	0.50	1.21	1.23	1.19	0.93	0.94
N-acetylcysteine	ME726447	0.51	1.11	1.25	1.08	1.03	1.02
phosphate	ME726476	0.99	0.84	1.22	0.88	1.10	0.98
glycerol 3-phosphate	ME726397	0.79	0.93	1.34	0.84	1.17	0.93
choline	ME726351	0.90	1.00	1.40	0.84	1.02	0.84
glycerophosphorylcholine (GPC)	ME726399	0.89	0.95	1.37	0.86	1.00	0.93
1-methyl-4-imidazoleacetate	ME726286	0.69	1.25	0.97	0.96	1.12	1.01
thioproline	ME726507	0.68	1.29	1.06	0.99	1.14	0.84
methionine sulfoxide	ME726432	0.79	1.38	1.04	0.89	1.03	0.88
4-acetamidobutanoate	ME726311	0.88	1.33	0.95	0.90	1.04	0.90
trigonelline (N^-methylnicotinate)	ME726510	0.81	1.37	0.94	0.93	1.03	0.91
phenylalanine	ME726473	0.87	1.27	1.10	0.98	0.92	0.86
AMP	ME726333	0.87	1.26	1.11	0.89	1.03	0.84
N-acetylaspartate (NAA)	ME726446	0.87	1.27	1.05	0.91	0.99	0.91
proline	ME726480	0.76	1.34	1.23	1.00	0.86	0.81
5^- GMP	ME726315	0.82	1.44	1.11	0.97	0.84	0.82
tyrosine	ME726516	0.89	1.39	1.03	1.01	0.86	0.82
glycylvaline	ME726404	0.91	1.03	1.01	1.17	0.77	1.11
nicotinamide	ME726460	1.03	1.18	1.04	1.01	1.03	0.71
N-acetylglucosaminylasparagine	ME726449	1.08	1.07	0.93	1.16	0.84	0.92
pterin	ME726484	0.97	1.16	1.04	1.03	0.83	0.97
pyridoxal	ME726486	0.95	1.16	0.98	1.01	0.92	0.99
asparagine	ME726337	0.97	1.23	0.87	1.12	0.86	0.94
serine	ME726496	1.04	1.18	0.84	1.04	0.90	0.98
5-hydroxylysine	ME726321	0.97	1.27	0.87	0.97	0.96	0.96
valine	ME726521	0.90	1.32	0.96	1.00	0.91	0.91
prolylglycine	ME726481	1.15	1.08	0.94	0.89	1.03	0.91
3-amino-2-piperidone	ME726301	0.94	1.01	1.04	0.86	1.12	1.03
glycerophosphoethanolamine	ME726398	0.91	1.12	0.97	0.94	1.10	0.96
isoleucine	ME726420	0.88	1.05	1.10	1.00	1.03	0.94
leucine	ME726426	1.06	1.02	0.99	1.02	0.94	0.98
cystine	ME726361	0.97	0.97	1.04	1.06	0.95	1.01
lysine	ME726429	0.95	1.00	1.01	1.03	1.01	1.00
glutamine	ME726393	1.08	1.37	0.27	1.19	1.00	1.10
N-monomethylarginine	ME726466	1.29	0.98	0.74	1.16	0.78	1.05
C-glycosyltryptophan	ME726350	0.92	1.32	0.65	1.32	0.76	1.02
dimethylarginine (ADMA + SDMA)	ME726367	1.07	1.27	0.72	1.18	0.80	0.96
arginine	ME726335	1.23	0.85	0.85	1.50	0.39	1.18
argininosuccinate	ME726336	1.04	1.21	1.08	1.33	0.50	0.84
glycerophosphoserine*	ME726400	0.97	0.88	1.22	1.40	0.58	0.96
ophthalmate	ME726468	0.09	2.57	0.61	0.74	1.90	0.09
glutathione, oxidized (GSSG)	ME726395	0.13	1.28	1.25	0.74	2.46	0.13
gamma-glutamylcitrulline*	ME726376	0.59	1.97	0.89	0.11	1.86	0.59
gamma-glutamyl-epsilon-lysine	ME726378	0.44	1.14	1.15	0.36	2.00	0.91

Factors:

F1	Genotype:EXOC5_KD
F2	Genotype:EXOC5_KO
F3	Genotype:EXOC5_OE
F4	Genotype:IFT88_KO
F5	Genotype:IFT88_KO_WT
F6	Genotype:WT

Data matrix