Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST002876)

(Analysis AN004713)

Metabolite	Structure	F1	F2	F3	F4	F5	F6
bilirubin	ME746668	1.62	0.46	0.78	0.63	0.64	3.62
sarcosine	ME746789	0.00	NA	NA	0.00	2.81	1.46
1-phenylethylamine	ME746632	0.53	2.14	0.34	2.03	0.55	0.35
N-carbamoyl-L-aspartate	ME746765	2.27	0.76	0.34	1.08	0.55	NA
uric acid	ME746810	2.82	0.67	0.69	0.52	0.65	0.66
glycerol 2/3-phosphate	ME746726	0.84	0.64	2.95	0.47	0.46	0.63
N-acetylaspartic acid	ME746759	0.85	1.21	2.20	0.40	0.46	0.88
GTP	ME746729	0.58	1.48	2.15	0.57	0.58	0.63
CTP	ME746685	0.82	1.43	2.20	0.63	0.51	0.40
ATP / dGTP	ME746665	0.84	1.59	2.04	0.51	0.52	0.50
UTP	ME746812	0.93	1.61	2.05	0.44	0.52	0.44
choline+	ME746676	0.46	0.50	1.33	0.91	0.99	1.81
N1/N8-acetylspermidine	ME746757	0.15	0.27	0.80	1.43	1.45	1.89
aconitic acid	ME746652	0.16	0.50	0.97	1.08	1.60	1.70
ManNAC	ME746753	0.47	0.30	0.98	0.96	1.68	1.43
thymine	ME746801	0.76	0.57	NA	1.46	0.78	1.42
vitamin B2	ME746814	0.73	0.52	NA	1.17	1.27	1.01
IMP	ME746741	0.70	0.53	0.43	2.09	1.72	0.54
adenylosuccinate	ME746655	0.04	0.05	NA	1.74	1.16	1.06
acetoin	ME746649	0.51	0.52	0.44	1.56	1.84	1.13
NAD+	ME746764	0.48	0.47	0.55	1.72	1.59	1.19
adenosine	ME746654	0.64	0.39	0.28	1.59	1.61	1.49
uridine	ME746811	0.88	0.39	0.28	1.59	1.60	1.26
hypoxanthine	ME746739	0.50	0.17	0.09	1.95	2.20	1.09
inosine	ME746742	0.63	0.17	0.11	1.89	1.89	1.31
guanine	ME746732	0.61	0.18	0.07	1.58	1.87	1.69
cytidine	ME746689	0.57	0.12	0.07	1.89	1.72	1.62
UMP	ME746808	0.26	0.21	0.14	1.99	1.83	1.57
AMP / dGMP	ME746660	0.38	0.31	0.22	1.86	1.63	1.61
CMP	ME746681	0.30	0.28	0.24	1.79	1.77	1.62
GMP	ME746728	0.29	0.25	0.21	1.80	1.74	1.71
O-succinyl-homoserine	ME746773	0.77	NA	1.13	0.85	1.26	NA
deoxyadenosine	ME746693	2.29	1.51	0.81	0.23	0.16	NA
"F-1,6/2,6-DP"	ME746708	2.39	1.19	1.35	0.31	0.22	0.30
guanidinoacetate	ME746731	2.32	1.33	1.83	0.19	0.17	0.16
carnosine	ME746673	1.59	1.65	0.59	0.68	0.66	0.84
homocysteine	ME746735	1.86	1.41	0.90	0.79	0.84	0.19
thiamine diphosphate+	ME746797	1.69	1.98	0.93	0.60	0.57	0.22
spermidine	ME746793	2.00	1.88	0.94	0.42	0.37	0.39
acetylcarnitine+	ME746650	1.93	1.67	0.93	0.50	0.53	0.43
thiamine+	ME746799	2.04	1.57	0.76	0.60	0.54	0.49
thymidine	ME746800	2.07	1.51	0.85	0.48	0.66	0.43
D-sedoheptulose-7-phosphate	ME746705	1.17	1.87	1.24	0.71	0.71	0.30
glutamine	ME746722	1.32	1.55	1.20	0.40	0.55	0.98
D-galactosamine/glucosamine-1/6-phosphate	ME746699	1.47	1.02	1.48	0.90	0.36	0.33
D-ribose-1/5-phosphate / D-ribulose 5-phosphate	ME746703	1.35	1.38	1.57	0.63	0.59	0.34
nicotinamide	ME746767	1.63	1.46	1.43	0.44	0.46	0.58
D-sedoheptulose	ME746704	0.70	1.02	1.19	NA	0.65	1.35
tryptamine	ME746802	1.40	1.04	0.44	NA	0.49	1.25
6-phosphogluconic acid	ME746648	1.13	0.86	0.99	1.23	NA	0.51
deoxyinosine	ME746697	1.52	0.64	0.38	0.61	1.47	0.85
glutathione disulfide	ME746724	1.72	0.97	0.65	0.77	1.40	0.50
dihydroorotate	ME746701	1.91	0.71	0.36	1.37	1.37	0.27
orotic acid	ME746772	1.32	1.02	0.56	1.19	1.48	0.42
a-KG	ME746657	1.67	1.17	0.51	1.28	1.14	0.22
3-phosphohydroxypyruvic acid	ME746640	1.57	0.91	0.21	1.21	1.08	0.28
dehydroascorbic acid	ME746692	1.43	1.09	0.16	1.06	1.09	0.42
guanosine	ME746733	0.95	0.60	0.42	1.90	0.97	0.84
citraconic acid	ME746677	0.94	0.94	0.93	1.73	0.83	0.63
L-cysteic acid	ME746746	0.80	0.95	0.82	1.69	0.81	0.91
methylmalonic acid	ME746756	0.86	1.33	0.75	0.52	0.70	1.85
cystathionine	ME746686	1.02	1.26	0.76	0.80	0.80	1.36
deoxyguanosine	ME746696	0.84	1.31	0.61	0.83	0.94	1.45
fructose / mannose	ME746712	0.58	1.02	0.95	0.70	1.16	1.60
L-NMMA	ME746748	0.63	1.04	0.98	0.80	1.34	1.21
citramalic acid	ME746678	0.58	1.39	0.84	1.18	1.06	0.96
GABA	ME746714	0.59	1.43	1.14	0.67	1.13	1.03
malic acid	ME746751	1.10	0.66	0.77	1.51	1.30	0.66
dTMP	ME746706	0.79	0.89	0.53	1.44	1.46	0.90
adenine	ME746653	0.80	0.70	0.68	1.37	1.67	0.79
glutathione	ME746723	0.81	0.61	0.62	1.50	1.62	0.83
succinic acid	ME746795	1.03	0.62	0.60	1.47	1.27	1.01
D-galactonic acid / D-gluconic acid	ME746698	0.78	0.75	0.62	1.25	1.46	1.14
proline	ME746780	0.95	0.80	0.65	1.22	1.35	1.03
nicotinamide riboside+	ME746768	0.91	0.60	0.89	1.25	0.97	1.38
CDP	ME746674	0.51	0.85	0.81	1.25	1.34	1.24
GDP	ME746719	0.54	0.79	0.94	1.14	1.24	1.35
mesaconic acid	ME746754	0.45	0.70	0.89	1.13	1.41	1.42
XMP	ME746816	0.46	0.68	0.82	1.59	1.34	1.11
y-glutamylcysteine	ME746818	0.70	0.68	0.85	1.35	1.33	1.09
2-HG	ME746635	0.54	0.78	0.79	1.42	1.41	1.06
UDP	ME746805	0.60	0.76	0.67	1.42	1.44	1.12
3-hydroxypropanoic acid	ME746639	0.49	1.00	1.02	1.46	1.00	1.03
phenylephrine / synephrine	ME746777	0.74	1.18	0.75	1.01	1.11	1.21
ADP / dGDP	ME746656	0.67	0.87	0.84	1.19	1.28	1.15
phosphorylcholine+	ME746779	0.76	0.90	0.88	1.16	1.22	1.09
F1P	ME746709	0.65	0.98	0.93	1.09	1.08	1.14
GDP-L-fucose	ME746720	0.72	0.96	0.98	1.22	1.02	1.10
FAD	ME746711	0.73	0.77	1.01	0.91	1.62	0.93
"cAMP(2^,3^) / cAMP(3^,5^)"	ME746671	0.68	0.61	1.09	1.01	1.14	1.10
phenethylamine	ME746775	0.61	0.60	1.24	1.04	1.29	1.17
coenzyme A	ME746682	1.05	1.48	0.74	1.47	0.53	0.59
GAP / DHAP	ME746718	0.89	1.33	1.24	1.17	0.77	0.60
glyceric acid	ME746725	1.40	0.60	0.52	1.23	1.25	1.01
lactic acid	ME746744	1.44	0.76	0.80	1.37	0.92	0.72
serine	ME746790	0.91	1.22	1.57	0.61	0.60	1.08
carnitine+	ME746672	1.18	1.23	1.30	0.69	0.77	0.82
putrescine	ME746782	0.84	1.33	1.41	0.73	0.91	0.78
2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine	ME746634	1.02	1.01	1.08	0.70	0.93	1.27
deoxycarnitine+	ME746694	0.89	0.99	1.18	0.88	0.85	1.21
5-methylcytosine	ME746645	0.80	0.87	1.11	0.92	0.97	1.33
lysine	ME746749	0.74	0.93	1.21	0.84	1.06	1.22
F6P / G1P / G6P	ME746710	0.73	1.07	1.51	0.83	0.89	0.96
N-acetylglucosamine 1/6-phosphate	ME746762	0.65	1.01	1.44	0.93	0.93	1.03
phosphocreatine	ME746778	0.77	1.24	1.18	0.98	0.98	0.86
UDP-N-acetyl-galactosamine/UDP-N-acetyl-glucosamine	ME746807	0.82	1.04	1.21	1.04	0.95	0.94
anserine	ME746661	1.17	0.71	1.48	0.74	0.89	1.12
aspartic acid	ME746664	0.82	0.86	1.54	0.74	0.81	1.22
ornithine	ME746771	0.73	0.86	1.57	0.51	0.97	1.36
cytosine	ME746690	1.48	1.26	0.82	0.83	0.92	0.69
deoxycytidine	ME746695	1.62	1.34	0.77	0.77	0.87	0.63
2-keto-isovaleric acid	ME746637	1.61	1.12	0.77	1.06	0.90	0.54
fumaric acid	ME746713	1.42	0.98	0.94	1.10	0.97	0.60
N1-acetylspermine	ME746758	1.33	0.99	0.78	0.74	0.99	1.17
sorbitol / galactitol / L-iditol / manitol	ME746792	1.40	0.83	0.99	0.74	0.83	1.19
2-hydroxybutanoic acid	ME746636	1.97	0.73	0.60	0.83	0.92	0.95
2- / 3-phosphoglycerate	ME746633	1.73	1.08	0.87	0.76	0.58	0.98
3- / 7-methylguanine	ME746638	1.37	0.83	0.95	1.00	0.96	0.89
maleic acid	ME746750	1.74	0.85	0.75	1.05	0.76	0.85
4-hydroxybutanoic acid	ME746642	1.63	0.84	0.83	0.89	0.94	0.88
galactose / glucose	ME746716	1.74	0.78	0.92	0.79	0.85	0.91
3-ureidopropionic acid	ME746641	1.41	0.98	1.25	0.65	1.11	0.60
6-aminohexanoate	ME746647	1.11	1.08	1.25	0.72	1.16	0.51
butyric acid / (iso)	ME746670	0.93	1.08	0.96	1.14	0.97	0.91
CDP-choline+	ME746675	0.90	1.06	0.90	1.17	1.11	0.86
citrulline	ME746680	1.04	1.07	0.86	1.00	1.04	0.99
spermine	ME746794	1.03	1.05	1.01	1.01	0.94	0.97
N-acetyl-L-glutamic acid	ME746763	0.93	1.13	1.01	0.93	1.05	0.95
glycine	ME746727	1.02	1.09	0.98	0.92	1.03	0.95
N-formyl-L-methionine	ME746766	0.97	1.07	0.98	0.89	1.09	1.00
b-alanine	ME746666	0.92	0.89	1.01	1.00	1.15	1.02
cystine	ME746688	0.97	0.88	0.98	1.07	1.14	0.95
N-acetyl-DL-serine / O-acetyl-L-serine	ME746761	0.96	0.99	0.99	0.97	1.13	0.95
xylitol / arabitol / ribito	ME746817	0.90	0.96	1.06	1.04	1.10	0.94
arginine	ME746662	0.87	1.03	0.92	0.96	1.16	1.06
citrate / citrate(iso)	ME746679	0.80	0.98	1.04	0.99	1.21	0.99
UDP-D-galactose / UDP-D-glucose	ME746806	0.78	1.03	1.01	1.07	1.18	0.94
hydroxypyruvic acid	ME746738	1.13	0.70	0.93	1.02	1.13	1.09
malonic acid	ME746752	1.09	0.93	0.94	1.01	0.99	1.05
epinephrine / normetanephrine	ME746707	1.04	0.91	0.95	0.87	1.03	1.19
imidazole-4-acetate	ME746740	1.00	0.96	1.00	0.97	0.90	1.19
GalNAC / GlcNAC	ME746717	1.17	0.90	1.25	0.88	1.04	0.76
acetylcholine+	ME746651	1.08	1.11	1.18	0.81	0.89	0.93
taurine	ME746796	1.01	0.97	1.14	0.89	1.01	0.98
thiamine phosphate+	ME746798	1.18	1.25	0.88	0.98	0.85	0.87
homoserine / threonine / allothreonine	ME746736	1.10	1.30	1.09	0.79	0.91	0.82
pyrroline hydroxycarboxylic acid	ME746785	1.21	1.26	1.06	0.80	0.85	0.83
4-hydroxyproline / 5-aminolevulinate	ME746643	1.08	1.06	1.05	0.79	1.00	1.02
methionine	ME746755	1.15	1.13	1.00	0.79	0.96	0.97
valine / norvaline	ME746813	1.16	1.12	1.04	0.80	0.94	0.94
serotonin	ME746791	1.24	1.17	0.96	0.78	0.97	0.87
tyrosine	ME746804	1.24	1.16	0.88	0.87	0.97	0.87
asparagine	ME746663	1.11	1.22	0.92	0.79	1.03	0.93
histidine	ME746734	1.09	1.10	0.93	0.88	1.07	0.93
tryptophan	ME746803	1.16	1.06	0.91	0.83	1.05	0.98
leucine / leucine(iso) / norleucine	ME746747	1.22	1.11	0.92	0.84	1.00	0.92
phenylalanine	ME746776	1.18	1.13	0.95	0.82	0.99	0.94
galactosamine / glucosamine / mannosamine	ME746715	1.25	0.99	0.86	0.89	0.94	1.07
guanidine	ME746730	1.34	0.93	0.96	0.90	0.87	1.01
pseudouridine	ME746781	1.29	0.95	0.92	0.78	1.07	0.97
betaine+	ME746667	1.17	0.98	0.93	0.91	1.07	0.94
pyridoxal	ME746783	1.23	1.00	0.92	0.95	0.98	0.92
D-glucuronolactone / D-galacturonolactone	ME746700	1.30	1.10	0.88	1.04	1.00	0.69
norepinephrine / pyridoxine	ME746770	1.37	1.10	0.82	0.93	1.00	0.77
allantoin	ME746659	1.26	1.05	0.95	0.88	1.05	0.82
creatinine	ME746684	1.35	1.01	0.90	0.90	1.05	0.79
xanthine	ME746815	1.34	1.00	0.90	0.95	1.03	0.77
alanine	ME746658	1.27	1.29	0.86	0.83	1.02	0.74
creatine	ME746683	1.26	1.21	0.95	0.86	0.98	0.74
pantothenic acid	ME746774	1.14	1.17	0.82	0.99	1.13	0.74
hydroxyphenyllactic acid / HVA	ME746737	1.23	1.22	0.75	0.91	1.10	0.78
kynurenine	ME746743	1.27	1.10	0.80	0.88	1.13	0.83
S-adenosyl-L-methionine+	ME746788	0.98	1.20	0.95	0.98	1.16	0.72
N-acetyl-b-alanine / N-acetyl-alanine	ME746760	1.07	1.02	0.96	0.99	1.13	0.83
dCMP	ME746691	1.09	1.19	0.99	1.06	0.89	0.79
dimethylglycine	ME746702	1.07	1.13	1.01	0.96	1.04	0.79
glutamate	ME746721	1.09	1.13	0.99	0.94	1.03	0.82
N-methylaspartic acid	ME746769	1.15	1.15	1.01	0.94	0.97	0.77
pyroglutamic acid	ME746784	1.21	1.11	0.97	0.98	0.96	0.75
5-aminopentanoic acid	ME746644	1.05	1.08	0.85	0.89	1.51	0.62
uracil	ME746809	1.03	0.95	0.79	0.99	1.41	0.82
biotin	ME746669	0.89	1.01	0.65	1.17	1.37	0.92
5^-methylthioadenosine	ME746646	0.86	0.98	0.88	1.12	1.31	0.84
cysteine	ME746687	0.94	0.87	0.82	1.14	1.29	0.94
S-adenosyl-L-homocysteine	ME746787	1.15	1.17	0.83	1.23	1.01	0.62
L-arginino-succinate	ME746745	1.06	1.00	0.80	1.18	1.19	0.77
pyruvic acid	ME746786	1.05	0.91	0.97	1.23	1.15	0.70

Factors:

F1	Genotype:High NSD2 \| Treatment:Control
F2	Genotype:High NSD2 \| Treatment:Knockdown 1
F3	Genotype:High NSD2 \| Treatment:Knockdown 2
F4	Genotype:Low NSD2 \| Treatment:Control
F5	Genotype:Low NSD2 \| Treatment:Knockdown 1
F6	Genotype:Low NSD2 \| Treatment:Knockdown 2

Data matrix