Clustering data with hclust algorithm for (Study ST002878)
(Analysis AN004715)Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-trimethyllysine | ME746856 | 0.07 | 0.16 | 0.18 | 0.12 | 0.43 | 0.00 | 0.84 | 2.45 | 1.47 | 2.46 | 3.23 | 0.34 |
AIR | ME746824 | 0.05 | 1.28 | 1.42 | 1.28 | 1.56 | 1.47 | 0.02 | 1.04 | 1.10 | 1.04 | 1.08 | 1.05 |
imidazolepyruvate | ME746845 | 2.23 | 0.19 | 0.31 | 0.23 | 0.31 | 0.32 | 1.81 | 1.00 | 0.79 | 1.18 | 0.68 | 1.12 |
urocanate | ME746867 | 0.26 | 0.66 | 0.61 | 0.80 | 1.60 | 0.89 | 0.86 | 0.76 | 1.47 | 0.92 | 2.26 | 0.28 |
glycerophosphocholine | ME746839 | 0.83 | 0.48 | 0.50 | 0.49 | 0.53 | 0.57 | 1.59 | 1.14 | 1.12 | 1.07 | 1.04 | 1.19 |
guanine | ME746841 | 0.64 | 0.47 | 0.41 | 0.46 | 0.41 | 0.37 | 1.42 | 1.24 | 1.07 | 1.37 | 1.10 | 0.96 |
phosphocholine | ME746859 | 0.63 | 0.49 | 0.46 | 0.51 | 0.40 | 0.45 | 1.54 | 1.24 | 1.14 | 1.26 | 1.09 | 1.07 |
NAD+ | ME746853 | 0.63 | 0.43 | 0.40 | 0.45 | 0.40 | 0.40 | 1.46 | 1.04 | 1.08 | 1.16 | 1.11 | 1.11 |
threonine | ME746866 | 0.75 | 0.42 | 0.45 | 0.41 | 0.43 | 0.50 | 1.47 | 1.21 | 1.10 | 1.19 | 1.17 | 1.20 |
valine | ME746868 | 0.83 | 0.72 | 0.67 | 0.75 | 0.54 | 0.55 | 0.80 | 1.15 | 1.32 | 1.21 | 1.05 | 1.42 |
NADP+ | ME746854 | 0.87 | 0.73 | 0.59 | 0.89 | 0.48 | 0.63 | 1.21 | 1.13 | 1.13 | 1.08 | 1.07 | 0.94 |
adenosine | ME746823 | 0.57 | 0.86 | 0.62 | 0.61 | 0.61 | 0.79 | 1.14 | 1.34 | 1.10 | 1.01 | 1.11 | 0.96 |
betaine | ME746828 | 0.81 | 0.78 | 0.79 | 0.83 | 0.76 | 0.84 | 1.16 | 1.10 | 1.06 | 1.13 | 1.04 | 1.03 |
creatine | ME746833 | 0.72 | 0.69 | 0.70 | 0.73 | 0.71 | 0.85 | 1.13 | 1.13 | 1.10 | 1.11 | 1.15 | 1.09 |
gamma-butyrobetaine | ME746838 | 0.74 | 0.67 | 0.69 | 0.72 | 0.69 | 0.80 | 1.16 | 1.11 | 1.09 | 1.11 | 1.12 | 1.17 |
glycine | ME746840 | 0.68 | 0.70 | 0.75 | 0.91 | 0.71 | 0.76 | 0.89 | 1.14 | 1.07 | 0.99 | 1.23 | 1.32 |
phenylalanine | ME746858 | 0.71 | 0.63 | 0.72 | 0.70 | 0.63 | 0.85 | 0.95 | 1.19 | 0.92 | 1.24 | 1.21 | 1.27 |
leucine / isoleucine | ME746849 | 0.45 | 0.66 | 0.81 | 0.60 | 0.82 | 0.84 | 0.74 | 1.25 | 1.03 | 1.24 | 1.25 | 1.30 |
5^-methylthioadenosine | ME746820 | 0.40 | 0.43 | 0.46 | 0.60 | 0.63 | 0.88 | 0.90 | 1.10 | 1.15 | 1.00 | 1.33 | 1.57 |
lysine | ME746850 | 0.38 | 0.54 | 0.59 | 0.50 | 0.69 | 0.75 | 0.90 | 1.15 | 1.12 | 1.12 | 1.37 | 1.48 |
proline | ME746860 | 0.53 | 0.49 | 0.60 | 0.48 | 0.63 | 0.70 | 0.94 | 1.19 | 1.17 | 1.11 | 1.31 | 1.41 |
arginine | ME746826 | 0.49 | 0.59 | 0.62 | 0.56 | 0.67 | 0.64 | 1.04 | 1.19 | 1.02 | 1.28 | 1.26 | 1.26 |
alanine | ME746825 | 0.53 | 0.67 | 0.66 | 0.60 | 0.70 | 0.81 | 1.02 | 1.15 | 1.15 | 1.10 | 1.23 | 1.25 |
kynurenine | ME746847 | 0.57 | 0.57 | 0.70 | 0.55 | 0.74 | 0.68 | 0.90 | 1.18 | 1.24 | 1.07 | 1.37 | 1.24 |
dihydrourocanate | ME746837 | 0.31 | 0.51 | 0.67 | 0.53 | 0.64 | 0.76 | 1.32 | 1.19 | 1.14 | 1.16 | 1.14 | 1.20 |
adenine | ME746822 | 0.39 | 0.43 | 0.39 | 0.32 | 0.52 | 0.53 | 1.16 | 1.36 | 1.21 | 1.14 | 1.32 | 1.27 |
methionine | ME746851 | 0.50 | 0.44 | 0.51 | 0.42 | 0.50 | 0.49 | 1.14 | 1.25 | 1.15 | 1.27 | 1.27 | 1.32 |
imidazoleacetate | ME746844 | 0.44 | 0.35 | 0.49 | 0.36 | 0.54 | 0.82 | 0.80 | 1.19 | 1.25 | 0.97 | 1.36 | 1.77 |
sarcosine | ME746864 | 0.37 | 0.40 | 0.71 | 0.39 | 0.72 | 0.65 | 0.76 | 1.11 | 1.02 | 0.81 | 1.58 | 1.41 |
propionyl-carnitine | ME746861 | 1.31 | 0.75 | 0.79 | 0.88 | 0.94 | 1.10 | 1.27 | 0.90 | 0.91 | 0.88 | 0.99 | 1.16 |
riboflavin | ME746862 | 0.95 | 0.78 | 0.70 | 0.75 | 0.84 | 0.90 | 1.13 | 0.96 | 0.87 | 0.98 | 1.10 | 1.22 |
acetyl-carnitine | ME746821 | 1.05 | 0.83 | 0.83 | 0.89 | 0.83 | 0.86 | 1.07 | 0.96 | 1.12 | 0.95 | 1.12 | 1.11 |
carnitine | ME746829 | 0.97 | 0.90 | 0.93 | 0.97 | 0.95 | 1.05 | 1.03 | 1.02 | 0.99 | 1.02 | 1.01 | 1.05 |
3-hydroxy-trimethyllysine | ME746819 | 1.27 | 0.98 | 0.99 | 1.17 | 0.99 | 0.95 | 1.16 | 0.99 | 0.98 | 0.97 | 0.95 | 0.86 |
nicotinamide | ME746855 | 1.23 | 1.02 | 1.01 | 0.97 | 0.95 | 1.05 | 0.84 | 1.16 | 0.91 | 1.26 | 0.92 | 0.81 |
L-2-aminobutyric acid | ME746848 | 1.04 | 0.48 | 0.45 | 0.65 | 1.18 | 0.54 | 1.40 | 1.04 | 1.16 | 1.09 | 1.07 | 0.96 |
hypoxanthine | ME746843 | 1.18 | 0.77 | 0.50 | 0.74 | 0.76 | 0.88 | 1.78 | 1.06 | 0.80 | 0.92 | 0.84 | 1.06 |
serine | ME746865 | 0.86 | 0.69 | 0.69 | 0.76 | 0.79 | 0.78 | 1.64 | 1.10 | 0.75 | 1.23 | 0.93 | 0.98 |
asparagine | ME746827 | 0.60 | 0.46 | 0.62 | 0.43 | 0.81 | 1.10 | 0.94 | 0.89 | 0.90 | 0.86 | 1.33 | 1.97 |
CDP-choline | ME746830 | 0.30 | 0.69 | 0.90 | 0.54 | 1.06 | 1.11 | 0.50 | 1.15 | 1.10 | 0.92 | 1.37 | 1.39 |
citrulline | ME746832 | 0.69 | 0.96 | 1.30 | 0.98 | 1.44 | 1.37 | 0.95 | 0.98 | 0.93 | 0.89 | 0.95 | 0.99 |
creatinine | ME746834 | 0.68 | 0.64 | 0.96 | 0.56 | 1.20 | 1.34 | 1.02 | 0.98 | 1.00 | 0.98 | 1.04 | 1.28 |
kynurenic acid | ME746846 | 0.61 | 0.70 | 1.12 | 0.82 | 1.48 | 1.28 | 0.88 | 0.80 | 0.92 | 0.91 | 1.02 | 1.47 |
ornithine | ME746857 | 0.57 | 0.96 | 1.07 | 0.92 | 1.02 | 1.00 | 0.91 | 1.04 | 0.96 | 1.06 | 1.07 | 1.16 |
S-adenosyl-methionine | ME746863 | 0.66 | 0.77 | 0.88 | 0.74 | 1.09 | 1.03 | 0.81 | 0.90 | 1.06 | 0.90 | 1.21 | 1.46 |
choline | ME746831 | 0.02 | 0.03 | 0.02 | 0.04 | 0.03 | 0.01 | 1.59 | 1.23 | 1.13 | 1.52 | 1.28 | 1.23 |
cystathionine | ME746835 | 0.11 | 0.17 | 0.23 | 0.09 | 0.47 | 0.10 | 1.50 | 1.20 | 1.17 | 1.25 | 1.34 | 1.11 |
cysteine-glutathione disulfide | ME746836 | 0.06 | 0.04 | 0.06 | 0.06 | 0.06 | 0.07 | 1.76 | 1.12 | 0.67 | 1.05 | 1.74 | 2.19 |
histamine | ME746842 | 0.16 | 0.19 | 0.21 | 0.22 | 0.23 | 0.33 | 0.95 | 1.31 | 1.30 | 1.21 | 1.59 | 2.00 |
methioninesulfoxide | ME746852 | 0.10 | 0.18 | 0.16 | 0.15 | 0.16 | NA | 0.88 | 0.98 | 1.10 | 1.84 | 1.36 | 2.59 |
Factors:
F1 | Genotype:Akita | U13C Glucose Labelling Timepoint:0 minutes |
F2 | Genotype:Akita | U13C Glucose Labelling Timepoint:1 hour |
F3 | Genotype:Akita | U13C Glucose Labelling Timepoint:2 hours |
F4 | Genotype:Akita | U13C Glucose Labelling Timepoint:30 minutes |
F5 | Genotype:Akita | U13C Glucose Labelling Timepoint:3 hours |
F6 | Genotype:Akita | U13C Glucose Labelling Timepoint:4 hours |
F7 | Genotype:Wild Type | U13C Glucose Labelling Timepoint:0 minutes |
F8 | Genotype:Wild Type | U13C Glucose Labelling Timepoint:1 hour |
F9 | Genotype:Wild Type | U13C Glucose Labelling Timepoint:2 hours |
F10 | Genotype:Wild Type | U13C Glucose Labelling Timepoint:30 minutes |
F11 | Genotype:Wild Type | U13C Glucose Labelling Timepoint:3 hours |
F12 | Genotype:Wild Type | U13C Glucose Labelling Timepoint:4 hours |