Clustering data with hclust algorithm for (Study ST002950)
HILIC NEGATIVE ION MODE (Analysis AN004839)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|---|
| N-Acetylglucosamine | ME763962 | 0.46 | 0.79 | 0.80 | 1.28 | 1.46 | 1.45 | 0.02 | 0.02 |
| Verbascose | ME763984 | 0.06 | 0.07 | 0.07 | 1.71 | 2.15 | 2.01 | 0.00 | NA |
| Glucose-1-phosphate | ME763942 | 1.13 | 1.02 | 1.04 | NA | NA | NA | 0.01 | NA |
| Glucose-6-phosphate | ME763943 | 1.14 | 1.01 | 1.06 | NA | NA | NA | 0.02 | NA |
| Ferulic acid | ME763937 | 0.37 | 0.99 | 1.07 | 1.33 | 1.50 | 1.27 | 0.53 | 0.27 |
| Glutamic acid | ME763944 | 1.07 | 1.12 | 1.16 | NA | NA | NA | 0.02 | NA |
| 1,11-Undecanedicarboxylic acid | ME763913 | 1.04 | 0.90 | 1.69 | NA | NA | NA | 0.58 | NA |
| Maltotriose | ME763959 | 0.03 | 0.01 | 0.03 | 2.15 | 2.06 | 2.30 | 0.00 | 0.00 |
| 2-Hydroxyquinoline | ME763917 | 0.96 | 1.16 | 1.14 | NA | NA | NA | 0.08 | NA |
| Aspartic acid | ME763928 | 1.22 | 0.96 | 1.15 | NA | NA | NA | 0.03 | NA |
| Tryptophan | ME763978 | 0.84 | 0.80 | 0.50 | 1.30 | 1.42 | 0.86 | 0.02 | 0.01 |
| 10-Hydroxydecanoic acid | ME763914 | 0.89 | 1.23 | 1.11 | NA | NA | NA | 0.33 | NA |
| Histidine | ME763950 | 0.64 | 0.59 | 0.65 | 1.56 | 1.53 | 1.65 | 0.10 | 0.13 |
| Glimepiride | ME763941 | 0.98 | 0.79 | 0.93 | 0.58 | 1.71 | 1.51 | 0.69 | 0.43 |
| Guanosine | ME763948 | 0.97 | 1.32 | 1.10 | 0.91 | 0.91 | 0.88 | 0.04 | NA |
| Glutaric acid | ME763946 | 0.48 | 0.68 | 4.34 | 0.18 | 0.42 | 9.68 | 0.05 | 0.03 |
| Serine | ME763974 | 1.17 | 1.25 | 1.30 | 0.99 | 0.89 | 0.99 | 0.13 | 0.16 |
| Galactose | ME763940 | 0.14 | 0.15 | 0.15 | 2.02 | 2.09 | 1.99 | 0.03 | 0.02 |
| Dihydro-4,4-dimethyl-2,3-furandione | ME763934 | 1.10 | 1.04 | 1.11 | NA | NA | NA | 0.03 | NA |
| Docosahexanoic acid | ME763935 | 1.33 | 2.05 | 1.88 | 0.47 | 0.19 | 0.35 | 0.71 | 0.00 |
| Fructose-1-phosphate | ME763939 | 1.23 | 1.15 | 1.30 | 0.98 | 0.92 | 0.94 | 0.01 | 0.01 |
| Uridine | ME763979 | 0.88 | 0.88 | 0.94 | 1.37 | 1.23 | 1.38 | 0.02 | 0.01 |
| Glutathione (reduced) | ME763947 | 1.07 | 0.16 | 0.44 | 1.42 | 1.77 | 1.54 | 0.03 | 0.09 |
| Erythronolactone | ME763936 | 0.70 | 0.16 | 5.62 | 0.05 | 0.39 | 10.50 | 0.04 | 0.02 |
| Carnosine | ME763929 | 1.01 | 1.11 | 1.15 | NA | NA | NA | 0.04 | NA |
| Uridine 5^-monophosphate | ME763980 | 0.22 | 0.17 | 0.20 | 1.68 | 2.28 | 1.96 | 0.00 | 0.01 |
| Flavin adenine dinucleotide | ME763938 | 1.13 | 1.11 | 1.17 | 0.91 | 1.14 | 1.02 | 0.01 | 0.00 |
| Xanthosine | ME763985 | 0.13 | 0.22 | 0.17 | 2.14 | 1.47 | 1.99 | NA | NA |
| Cortisone | ME763931 | 1.12 | 1.35 | 1.32 | 0.77 | 1.08 | 0.96 | 0.22 | 0.09 |
| Methioninesulfoxide | ME763960 | 0.77 | 1.31 | 1.12 | NA | NA | NA | 0.05 | NA |
| Trehalose | ME763977 | 0.12 | 0.13 | 0.13 | 2.56 | 1.54 | 2.30 | 0.01 | 0.01 |
| Taurocholic acid | ME763976 | 1.79 | 0.38 | 1.00 | NA | NA | NA | 0.01 | NA |
| Methylsuccinic acid | ME763961 | 0.81 | 0.84 | 2.85 | 0.50 | 0.62 | 6.37 | 0.24 | 0.03 |
| Cnidioside A | ME763930 | 0.02 | 0.03 | 0.02 | 1.91 | 2.14 | 1.33 | NA | NA |
| Adenylosuccinic acid | ME763925 | 1.15 | 1.54 | 1.08 | 1.14 | 0.59 | 0.67 | 0.07 | 0.03 |
| Arginine | ME763927 | 1.07 | 1.10 | 1.15 | NA | NA | NA | 0.12 | NA |
| Phenylalanine | ME763967 | 0.71 | 0.72 | 0.59 | 1.55 | 1.47 | 1.28 | 0.02 | 0.02 |
| Uridine diphosphate glucuronic acid | ME763982 | 1.50 | 1.39 | 1.24 | 0.29 | 0.89 | 0.42 | NA | NA |
| P-Toluenesulfonic acid | ME763965 | 0.95 | 0.27 | 0.57 | 1.42 | 1.68 | 1.57 | 0.19 | 0.23 |
| N-epsilon-Acetyllysine | ME763963 | 0.28 | 0.35 | 0.30 | 1.71 | 1.83 | 1.71 | 0.01 | 0.01 |
| Pantothenic acid | ME763966 | 1.69 | 1.80 | 1.82 | 0.38 | 0.31 | 0.38 | 0.01 | 0.00 |
| Taurine | ME763975 | 1.09 | 1.11 | 1.10 | NA | NA | NA | 0.00 | NA |
| Phenylpyruvic acid | ME763968 | 0.99 | 0.79 | 0.95 | 1.03 | 1.26 | 1.23 | 0.03 | 0.03 |
| Phosphoenolpyruvic acid | ME763969 | 0.54 | 1.32 | 0.92 | 0.91 | 1.59 | 0.90 | 0.03 | 0.01 |
| Ribose-5-phosphate | ME763973 | 0.77 | 1.34 | 1.08 | 1.20 | 0.99 | 1.06 | 0.01 | 0.01 |
| Pyruvic acid | ME763972 | 1.00 | 0.76 | 0.02 | 1.81 | 1.27 | 0.05 | 0.07 | 0.09 |
| N-Methylalanine | ME763964 | 1.59 | 1.64 | 1.68 | 0.56 | 0.60 | 0.60 | 0.01 | 0.00 |
| Propionic acid | ME763970 | 0.81 | 0.75 | 0.99 | 1.02 | 1.31 | 1.53 | NA | NA |
| Adenine | ME763921 | 1.60 | 1.56 | 1.94 | 0.48 | 0.64 | 0.65 | 0.10 | 0.04 |
| Adenosine | ME763922 | 3.13 | 0.75 | 1.76 | 0.14 | 0.22 | 0.13 | 0.01 | 0.00 |
| Pyroglutamic acid | ME763971 | 1.06 | 1.12 | 1.16 | NA | NA | NA | 0.02 | NA |
| Uridine diphosphate galactose | ME763981 | 0.10 | 0.05 | 0.08 | 1.90 | 2.12 | 1.88 | NA | 0.00 |
| 4-Methyl-2-oxovaleric Acid | ME763918 | 0.99 | 1.16 | 1.28 | NA | NA | NA | 0.04 | NA |
| 2-Deoxyuridine | ME763915 | 1.26 | 1.32 | 1.30 | 0.56 | 0.85 | 0.76 | NA | NA |
| 4,5,7-Trihydroxyisoflavone | ME763919 | 1.34 | 0.40 | 0.42 | 1.00 | 1.54 | 1.11 | NA | NA |
| Adenosine 5^-monophosphate | ME763924 | 1.37 | 0.86 | 1.15 | 0.91 | 1.24 | 1.10 | 0.01 | 0.01 |
| Lumichrome | ME763957 | 1.14 | 1.59 | 1.47 | 0.61 | 0.71 | 0.75 | 0.02 | NA |
| 2-Hydroxy-3-methylbutyric acid | ME763916 | 1.10 | 0.97 | 0.00 | 1.30 | 1.44 | 0.03 | 0.04 | 0.05 |
| Linoleic acid | ME763955 | 0.99 | 1.37 | 1.32 | 1.31 | 0.51 | 1.00 | 0.64 | 0.14 |
| Allantoin | ME763926 | 0.41 | 0.43 | 0.47 | 1.86 | 1.44 | 1.87 | 0.00 | 0.00 |
| Cytidine-5^-monophosphate | ME763932 | 0.71 | 0.79 | 0.81 | 1.18 | 1.38 | 1.18 | NA | 0.01 |
| Dehydroascorbic acid | ME763933 | 0.26 | 0.06 | 0.44 | 1.73 | 1.69 | 2.69 | NA | NA |
| Glutamine | ME763945 | 1.15 | 1.04 | 1.13 | NA | NA | NA | 0.01 | NA |
| Vanillin | ME763983 | 1.40 | 2.20 | 1.99 | 0.23 | 0.33 | 0.26 | 0.66 | 0.37 |
| Inosine-5-monophosphate | ME763952 | 1.30 | 2.49 | 1.96 | 0.31 | 0.23 | 0.28 | 0.02 | 0.00 |
| Leucine | ME763954 | 0.58 | 0.59 | 0.55 | 1.70 | 1.52 | 1.41 | 0.01 | 0.01 |
| Lactose A | ME763953 | 0.09 | 0.09 | 0.10 | 2.63 | 1.54 | 2.26 | 0.01 | 0.01 |
| Lysine | ME763958 | 1.08 | 1.08 | 1.17 | NA | NA | NA | 0.09 | NA |
| 9-(2,3-Dihydroxypropoxy)-9-oxononanoic acid | ME763920 | 0.74 | 0.97 | 0.88 | 1.35 | 1.20 | 1.19 | 0.46 | 0.34 |
| Liquiritigenin | ME763956 | 1.35 | 0.65 | 1.32 | NA | NA | NA | 0.15 | NA |
| Indoxyl sulfate | ME763951 | 0.79 | 0.99 | 0.94 | 0.98 | 1.29 | 1.10 | 0.00 | NA |
| Guanosine-5^-monophosphate | ME763949 | 0.68 | 0.74 | 0.72 | 1.36 | 1.57 | 1.41 | 0.02 | 0.03 |
Factors:
| F1 | Organ:Heart | Treatment:Control |
| F2 | Organ:Heart | Treatment:Expt |
| F3 | Organ:Heart | Treatment:QC1 |
| F4 | Organ:Liver | Treatment:Control |
| F5 | Organ:Liver | Treatment:Expt |
| F6 | Organ:Liver | Treatment:QC2 |
| F7 | Organ:QC3 | Treatment:QC3 |
| F8 | Organ:QC4 | Treatment:QC4 |
