Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003082)

(Analysis AN005040)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8
methionine-13C5-15N	ME801176	0.96	1.47	0.23	0.26	4.35	1.44	0.17	0.15
serotonin	ME801223	NA	NA	0.98	1.21	2.14	NA	NA	0.68
arginine-13C6-15N4	ME801268	1.20	1.16	0.63	0.58	3.15	1.34	0.29	0.35
threonine-13C4-15N	ME801170	1.29	1.31	0.59	0.63	2.68	1.29	0.27	0.33
histidine-13C6-15N3	ME801279	1.30	1.28	0.83	0.86	2.03	1.42	0.33	0.49
alanine-13C3-15N	ME801167	1.37	1.36	0.61	0.63	2.10	1.35	0.29	0.35
L-ALANINE_13C3	ME801173	1.37	1.36	0.61	0.63	2.10	1.35	0.29	0.35
cystine-13C6-15N2	ME801122	1.48	1.41	0.33	0.38	1.41	1.43	0.28	0.28
glycine_13C2-15N	ME801246	1.53	1.49	0.43	0.40	1.46	1.47	0.19	0.27
phenylalanine-13C9-15N	ME801123	1.56	1.50	0.46	0.47	1.62	1.48	0.24	0.27
serine-13C3-15N	ME801320	1.56	1.57	0.43	0.45	1.54	1.52	0.22	0.24
proline-13C5-15N	ME801212	1.54	1.46	0.60	0.61	1.71	1.49	0.32	0.35
Isoleucine-13C6-15N	ME801111	1.51	1.36	0.64	0.63	1.68	1.31	0.32	0.35
valine-13C5-15N	ME801321	1.44	1.41	0.60	0.61	1.67	1.38	0.33	0.35
tyrosine-13C9-15N	ME801140	1.43	1.39	0.57	0.56	1.93	1.40	0.29	0.33
leucine-13C6-15N	ME801358	1.47	1.50	0.52	0.53	1.82	1.30	0.32	0.31
lysine-13C6-15N2	ME801234	1.49	1.46	0.49	0.49	1.85	1.44	0.26	0.28
2-oxoadipate	ME801332	1.53	1.42	0.65	0.68	0.80	1.24	0.53	0.36
Ureidosuccinic_acid	ME801146	1.58	1.71	0.64	0.64	1.21	1.10	0.48	0.41
"glutamate-13C5,15N"	ME801230	1.49	1.51	0.60	0.59	1.10	1.37	0.42	0.35
GSSG-13C4_15N2	ME801308	1.53	1.53	0.64	0.59	1.09	1.39	0.33	0.34
Alpha-Lipoic Acid_unc	ME801144	1.63	1.57	0.61	0.64	1.15	1.45	0.35	0.35
Itaconic Acid	ME801159	1.54	1.57	0.58	0.61	1.23	1.43	0.36	0.33
aspartate-13C6-15N4	ME801232	1.44	1.42	0.66	0.67	1.15	1.32	0.49	0.41
glycerate	ME801292	1.57	1.54	0.72	0.74	1.20	1.42	0.44	0.43
2-hydroxyglutarate	ME801118	1.42	1.42	1.09	0.97	0.88	1.11	0.67	0.61
creatinine	ME801130	1.61	1.53	0.89	0.87	0.62	1.28	0.52	0.52
N-acetylglutamate	ME801329	1.59	1.48	1.08	0.86	0.81	1.28	0.33	0.53
hypotaurine	ME801245	0.97	1.06	0.82	NA	NA	NA	1.02	NA
AMP	ME801164	1.37	1.16	NA	0.01	NA	0.16	1.29	NA
UMP	ME801277	1.28	1.09	NA	NA	NA	0.08	1.28	NA
UDP-GlcNAc	ME801127	1.19	1.40	0.16	0.11	NA	NA	0.86	NA
IMP	ME801354	1.25	1.22	NA	0.30	NA	NA	0.76	NA
NAD+	ME801355	1.33	1.39	NA	0.29	NA	NA	0.64	NA
5-CH3-H4PteGlu	ME801206	1.34	2.84	0.16	NA	0.05	0.65	0.08	0.08
glycine	ME801312	1.60	1.71	0.54	0.65	0.59	0.91	0.94	0.33
inosine	ME801274	1.48	1.36	0.57	0.98	NA	0.34	1.35	0.48
orotate	ME801331	1.57	1.71	0.42	0.54	0.10	0.95	1.31	0.33
Glycerophosphocholine	ME801287	1.61	1.48	0.69	0.73	0.03	0.57	1.16	0.38
O-phosphoethanolamine	ME801282	1.63	1.55	0.59	0.51	NA	0.55	1.20	0.29
phosphocholine	ME801319	1.96	1.89	0.44	0.36	0.03	0.52	1.60	0.21
guanosine	ME801195	1.71	1.63	0.16	0.18	NA	0.90	1.01	0.12
S-Adenosyl-L-methionine	ME801160	1.78	1.70	0.22	0.23	0.00	1.14	0.95	0.13
uridine	ME801284	1.74	1.70	0.18	0.15	NA	1.08	0.85	0.12
cysteic_acid	ME801188	1.80	1.77	0.14	0.13	NA	0.73	1.21	0.11
phosphocreatine	ME801142	1.81	1.49	0.20	0.19	NA	0.69	1.05	0.19
saccharopine_unc	ME801179	1.40	1.29	0.28	0.29	0.38	1.84	0.28	0.22
adenine	ME801311	1.18	1.47	0.06	NA	0.55	1.34	0.45	0.07
beta-alanine	ME801295	0.97	1.26	NA	NA	0.53	1.24	NA	NA
3-hydroxyisobutyric_acid	ME801169	1.14	1.31	NA	NA	NA	1.08	0.32	NA
thymidine	ME801168	1.29	1.45	NA	NA	0.05	0.78	0.32	NA
choline	ME801205	1.35	1.26	0.00	NA	NA	1.69	0.00	0.00
Pyridoxal	ME801365	1.21	1.45	NA	NA	0.05	1.42	0.17	NA
3-methyl-2-oxopentanoic_acid	ME801251	1.05	2.49	0.34	0.49	NA	1.64	0.24	0.26
N-alpha-acetyllysine	ME801288	1.24	1.12	0.76	0.70	NA	1.36	0.42	0.74
2-hydroxybutyric_acid	ME801345	1.11	1.84	0.59	1.02	NA	1.16	0.39	0.46
cystine	ME801290	1.22	1.77	0.81	0.72	NA	1.12	0.44	0.44
citrulline	ME801180	1.38	1.50	0.97	1.21	0.07	1.29	0.26	0.63
tryptophan	ME801363	1.53	1.47	0.85	1.13	0.21	1.21	0.43	0.60
alanine	ME801286	1.68	1.60	0.94	0.85	0.02	1.29	0.61	0.52
creatine	ME801297	1.68	1.50	1.05	0.94	0.00	1.29	0.54	0.59
dimethylglicine	ME801342	1.48	1.46	0.79	0.74	NA	1.28	0.33	0.44
glutamine	ME801198	1.52	1.57	0.81	0.80	0.01	1.48	0.34	0.48
guanine	ME801333	1.85	1.77	0.01	0.01	0.01	1.73	0.42	0.01
N-acetylaspartate	ME801309	1.75	1.86	0.15	0.12	NA	1.80	0.28	0.14
quinolinic_acid	ME801315	1.92	1.58	0.15	0.13	NA	1.58	0.47	0.10
biotin	ME801155	1.74	1.80	0.11	0.10	NA	1.41	0.50	0.07
cytidine	ME801177	1.77	1.84	0.15	0.13	NA	1.40	0.52	0.08
cytosine	ME801187	1.80	1.84	0.12	0.12	NA	1.42	0.49	0.07
Pantothenate	ME801264	1.64	2.27	0.02	0.03	NA	1.82	0.42	0.01
asparagine	ME801156	1.46	2.20	0.30	0.32	0.02	1.47	0.54	0.18
asymmetric dimethylarginine	ME801114	1.59	2.12	0.23	0.24	0.00	1.67	0.43	0.14
methionine	ME801338	1.38	2.10	0.20	0.23	NA	1.59	0.36	0.13
arginine	ME801210	1.59	1.77	0.58	0.56	0.01	1.69	0.53	0.38
citrate	ME801303	1.60	1.64	0.80	0.81	0.06	1.70	0.44	0.43
histidine	ME801334	1.53	1.69	0.77	0.69	0.04	1.66	0.57	0.46
isoleucine	ME801313	1.59	1.66	0.52	0.59	0.01	1.33	0.46	0.30
Pipecolate	ME801248	1.65	1.60	0.48	0.49	NA	1.30	0.46	0.26
argininosuccinate_unc	ME801171	1.39	1.67	0.44	0.51	NA	1.41	0.58	0.29
threonine	ME801194	1.42	1.79	0.58	0.72	0.03	1.35	0.45	0.38
homocitrulline	ME801272	1.31	1.87	0.48	0.57	NA	1.42	0.35	0.29
carnitine	ME801348	1.53	1.82	0.58	0.61	0.00	1.42	0.47	0.35
betaine	ME801228	1.43	1.82	0.49	0.52	0.00	1.43	0.45	0.29
C5 Carnitines	ME801278	1.50	1.78	0.56	0.49	0.00	1.41	0.40	0.29
tyrosine	ME801328	1.42	1.96	0.46	0.52	0.20	1.42	0.55	0.28
phenylalanine	ME801283	1.59	2.09	0.51	0.56	0.11	1.47	0.54	0.31
proline	ME801255	1.66	2.01	0.44	0.45	0.01	1.44	0.63	0.26
serine	ME801220	1.66	1.87	0.43	0.41	0.24	1.51	0.36	0.23
lysine	ME801351	1.61	1.98	0.48	0.45	0.00	1.59	0.40	0.27
leucine	ME801298	1.56	1.91	0.39	0.40	0.01	1.34	0.43	0.23
valine	ME801138	1.63	1.81	0.44	0.47	0.03	1.43	0.45	0.25
hydroxyproline_gammaALA	ME801209	1.70	1.67	0.40	0.36	0.02	1.25	0.68	0.23
pseudouridine_unc	ME801280	1.65	1.64	0.31	0.35	NA	1.38	0.62	0.17
Methionine sulfoxide	ME801147	1.91	1.77	0.45	0.43	0.00	1.57	0.50	0.26
THYMINE	ME801120	1.88	1.72	0.54	0.59	0.08	1.39	0.51	0.34
kynurenine	ME801199	1.94	1.40	0.62	0.33	NA	1.22	0.44	0.25
S-Adenosyl-L-Homocysteine	ME801139	1.61	1.68	0.44	0.54	NA	1.03	0.79	0.42
lactic_acid	ME801126	1.54	1.54	0.67	0.74	0.01	1.02	0.69	0.41
uracil	ME801350	1.56	1.49	0.78	0.64	NA	0.91	0.71	0.37
Cholic acid	ME801269	0.01	0.07	1.34	2.90	NA	0.02	0.01	1.12
palmitate	ME801221	0.36	0.64	2.03	3.42	0.02	0.47	0.15	1.29
anserine	ME801202	0.46	0.41	4.12	1.59	NA	0.42	0.22	1.46
xanthine	ME801339	0.29	0.29	2.80	2.88	NA	0.05	0.36	2.02
phosphoenolpyruvate	ME801325	0.60	0.50	2.67	2.32	NA	0.02	0.59	1.27
uric acid	ME801259	0.47	0.53	2.76	2.25	NA	0.39	0.24	1.70
xanthosine	ME801343	0.46	0.56	3.12	2.61	0.12	0.47	0.16	1.62
carnosine	ME801257	0.75	0.73	2.53	1.91	NA	0.69	0.21	1.17
cystathionine	ME801243	0.81	0.58	2.76	1.45	NA	0.15	0.71	1.58
dTTP	ME801110	0.38	0.52	1.59	NA	NA	NA	NA	1.52
aspartate	ME801233	1.24	1.11	1.43	1.59	0.09	0.16	1.41	0.92
glutamate	ME801222	1.61	1.44	0.94	0.94	0.03	0.10	1.83	0.57
Nicotinic Acid	ME801163	1.01	1.14	1.77	0.91	1.07	0.82	0.50	0.82
INDOLE-3-ACETIC ACID	ME801300	0.55	0.55	1.53	2.23	NA	0.10	0.47	1.07
Ribose_Ribulose 5-phosphate_3Me-Lys	ME801359	0.45	0.62	1.82	2.22	NA	NA	0.35	1.10
6-phosphogluconate	ME801353	1.04	0.76	1.78	1.18	NA	NA	0.54	0.86
F6P_G1P	ME801157	0.97	0.73	1.67	1.73	NA	0.04	0.87	0.92
GSSG	ME801294	1.11	0.99	1.76	1.55	NA	0.14	1.03	0.82
Sedoheptulose-7-phosphate	ME801227	1.02	0.81	1.33	1.83	NA	NA	0.47	0.87
3-phosphoglycerate	ME801266	0.90	0.61	1.89	1.65	NA	NA	0.47	0.89
Ribose 1-phosphate_unc	ME801307	0.70	0.69	1.77	1.82	NA	NA	0.42	0.98
acetylcarnitine	ME801281	1.07	1.20	1.76	1.96	0.00	0.96	0.30	1.07
N-acetylphenylalanine	ME801189	0.87	1.02	1.62	1.71	NA	0.81	0.26	0.94
propionylcarnitine	ME801235	0.97	1.12	1.78	1.61	NA	0.92	0.23	0.96
malate	ME801330	0.97	1.04	1.82	1.91	0.42	0.72	0.61	1.28
taurine	ME801247	0.93	1.04	1.80	1.89	NA	0.43	0.81	1.17
Glycerol 3-Phosphate	ME801218	1.39	1.32	1.07	1.03	NA	0.79	0.63	0.57
hypoxanthine	ME801265	1.33	1.32	0.99	1.33	0.01	0.71	0.96	0.74
allantoin	ME801317	1.30	1.47	1.64	1.31	NA	0.78	0.33	0.65
guanidinoacetate	ME801260	1.19	1.50	1.55	1.21	0.02	0.94	0.54	0.74
Butyrylcarnitine	ME801131	1.29	1.37	1.38	0.98	0.01	1.06	0.33	0.65
ornithine	ME801193	1.36	1.34	1.23	1.06	0.11	1.19	0.60	0.72
HIAA	ME801129	1.20	0.84	1.14	1.45	NA	0.82	0.53	0.78
succinate	ME801145	1.07	1.14	1.79	1.35	0.12	0.77	0.51	0.83
Kynurenic Acid	ME801201	1.23	1.03	1.55	1.41	NA	0.81	0.60	0.90
niacinamide	ME801117	1.26	1.19	1.39	1.45	0.16	0.74	0.70	0.82
3-hydroxybutyric_acid	ME801217	1.03	1.55	0.86	1.52	NA	0.99	0.27	0.70
glucose	ME801263	1.27	1.19	1.08	1.00	NA	0.89	NA	0.66

Factors:

F1	Sample source:embryonic Serum \| Developmental Timepoint:E14.5 \| Maternal Treatment (injection):PolyIC \| Collection Timepoint:48h
F2	Sample source:embryonic Serum \| Developmental Timepoint:E14.5 \| Maternal Treatment (injection):saline \| Collection Timepoint:48h
F3	Sample source:maternal Serum \| Developmental Timepoint:E14.5 \| Maternal Treatment (injection):PolyIC \| Collection Timepoint:48h
F4	Sample source:maternal Serum \| Developmental Timepoint:E14.5 \| Maternal Treatment (injection):saline \| Collection Timepoint:48h
F5	Sample source:mock \| Developmental Timepoint:- \| Maternal Treatment (injection):- \| Collection Timepoint:-
F6	Sample source:pool embryonic CSF \| Developmental Timepoint:- \| Maternal Treatment (injection):- \| Collection Timepoint:-
F7	Sample source:pool Embryonic Serum \| Developmental Timepoint:- \| Maternal Treatment (injection):- \| Collection Timepoint:-
F8	Sample source:pool Maternal Serum \| Developmental Timepoint:- \| Maternal Treatment (injection):- \| Collection Timepoint:-

Data matrix