Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003177)

(Analysis AN005215)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8
IndolePyruvate	ME829728	0.88	1.12	2.23	0.94	0.76	0.72	0.35	9.63
Bilirubin	ME829717	2.40	2.95	2.42	0.30	0.12	0.11	2.58	0.05
Inosine	ME829709	0.05	1.13	4.41	0.10	0.88	0.60	0.07	0.29
Putrescine	ME829637	NA	1.24	3.64	1.59	0.58	0.55	1.56	NA
S-Adenosylmethionine	ME829715	1.91	0.65	0.45	2.26	0.34	0.68	1.79	0.96
D-Mannose	ME829689	2.34	0.75	0.98	1.44	0.83	1.21	1.60	NA
3-Hydroxy-L-kynurenine	ME829701	3.86	0.65	0.92	1.15	1.19	0.77	2.07	0.61
L-Proline	ME829647	3.24	1.06	0.69	0.89	1.14	0.69	1.28	0.22
Methylthioadenosine	ME829712	NA	0.57	1.63	1.22	0.76	0.99	3.69	NA
3-Hydroxyanthranilate	ME829679	NA	0.17	1.60	0.88	1.25	0.89	2.88	NA
N-Methylhistamine	ME829721	NA	0.64	0.73	0.76	1.19	0.90	2.54	NA
N1-Acetylspermine	ME829706	2.61	0.87	0.84	0.83	1.11	0.91	0.98	2.02
Cysteamine	ME829678	0.70	1.16	0.94	1.13	0.93	0.92	0.80	3.30
L-Aspartate	ME829668	0.61	0.67	0.66	1.06	1.10	1.01	1.34	2.72
Tyramine	ME829671	1.02	0.99	0.83	1.15	1.10	0.71	0.92	2.14
6-Methyladenosine	ME829710	0.37	1.56	1.85	2.40	0.55	0.57	0.68	0.84
O-Acetylcarnitine	ME829696	0.36	1.69	0.67	1.96	0.54	1.02	0.35	0.31
5-Hydroxyindoleacetate	ME829693	NA	0.57	2.24	0.27	1.38	0.77	1.21	NA
Anthranilate	ME829724	0.30	1.17	1.94	0.62	1.00	0.74	0.86	NA
1-Methylnicotinamide	ME829670	0.39	1.15	1.30	0.54	1.06	0.80	1.45	0.11
Salicyluric acid	ME829694	NA	0.68	1.53	0.45	1.11	1.02	1.81	NA
Betaine	ME829649	0.33	0.74	0.82	0.80	0.99	1.41	1.49	0.14
5-Hydroxy-L-tryptophan	ME829700	NA	0.82	1.03	0.83	1.20	0.92	0.96	NA
8-Hydroxy-deoxyguanosine	ME829711	NA	0.67	0.90	0.78	1.28	1.01	1.09	NA
Deoxyuridine	ME829702	NA	0.75	1.22	0.43	1.25	1.01	0.79	NA
O-Phosphotyrosine	ME829729	NA	0.74	0.93	0.53	1.32	1.03	0.85	NA
D-Sorbitol	ME829691	NA	1.00	0.25	0.48	1.52	0.74	1.14	NA
Pyridoxine	ME829685	NA	0.43	0.50	0.60	1.91	0.60	0.85	NA
Indole	ME829651	0.24	0.32	0.22	0.95	1.40	1.35	0.28	NA
Ethyl 4-aminobutyrate	ME829660	0.43	0.60	0.55	0.79	1.37	1.04	0.65	NA
Nicotinamide mononucleotide	ME829713	0.48	0.59	NA	0.73	1.26	0.97	0.71	NA
Guanosine 5^-monophosphate	ME829714	0.26	0.27	0.15	0.26	1.33	1.12	0.32	0.26
Trimethylamine	ME829634	0.35	0.77	0.58	0.45	1.24	1.28	0.30	0.40
Guanosine	ME829734	NA	0.61	NA	1.71	0.82	1.45	0.40	1.30
N(pi)-Methyl-L-histidine	ME829684	0.58	0.74	0.48	1.76	0.98	1.26	0.59	1.44
Cytosine	ME829645	0.58	0.45	0.65	1.32	1.22	1.22	0.51	1.08
D-Glucosamine	ME829688	0.52	0.45	0.52	1.25	1.18	1.35	0.74	1.12
Indolelactate	ME829698	0.64	0.72	0.57	0.94	1.17	1.19	0.63	1.29
L-Normetanephrine	ME829733	0.48	0.64	0.54	1.10	1.22	1.09	0.71	1.05
L-Arginine	ME829686	0.44	0.45	0.48	0.90	1.32	1.27	0.45	1.30
Cadaverine	ME829640	0.33	0.35	0.47	0.85	1.38	1.32	0.32	0.94
L-Glutamate	ME829676	0.28	0.35	0.43	0.90	1.40	1.30	0.24	0.96
L-Adrenaline	ME829727	0.43	0.44	0.41	0.73	1.14	1.68	0.66	0.89
Indole-3-acetate	ME829687	0.44	0.66	0.60	0.64	1.23	1.27	0.52	0.78
L-Histidine	ME829680	0.59	0.61	0.60	0.75	1.27	1.21	0.58	0.83
Tryptamine	ME829681	0.89	0.89	0.67	1.55	1.06	0.93	1.00	0.88
Xanthurenate	ME829723	0.70	0.77	0.60	0.99	1.10	1.20	0.78	1.66
L-Kynurenine	ME829699	0.78	0.78	0.76	0.98	1.11	1.08	1.19	0.85
4-Acetamidobutanoate	ME829672	0.91	0.65	0.68	0.99	1.19	1.15	0.78	0.84
N8-Acetylspermidine	ME829692	0.88	0.85	0.91	0.92	1.08	1.13	0.68	0.65
3-Acetamidopropanal	ME829718	1.18	0.85	0.84	0.91	1.16	0.96	0.91	0.68
L-Ornithine	ME829666	1.01	0.89	0.85	0.97	1.07	1.06	0.91	0.73
L-Tyrosine	ME829690	0.69	0.82	0.88	1.02	1.10	1.07	0.77	1.37
Creatinine	ME829646	0.86	0.82	0.77	1.09	1.10	1.08	0.76	0.99
L-Isoleucine	ME829664	0.68	0.75	0.74	1.22	1.11	1.10	0.74	1.21
Carnitine	ME829682	0.73	0.73	0.74	1.01	1.15	1.13	0.75	1.06
L-Alanine	ME829639	0.71	0.74	0.77	0.92	1.17	1.11	0.71	1.14
L-Lysine	ME829675	0.78	0.77	0.72	1.03	1.16	1.06	0.75	1.18
L-Homoserine	ME829652	0.74	0.82	0.80	1.03	1.12	1.06	0.74	1.19
L-Threonine	ME829653	0.74	0.82	0.79	1.02	1.12	1.07	0.74	1.15
L-Leucine	ME829665	0.71	0.82	0.79	1.09	1.10	1.09	0.74	1.22
L-Tryptophan	ME829697	0.72	0.85	0.83	1.12	1.09	1.05	0.75	1.17
1-Methylguanosine	ME829730	0.71	0.83	1.02	1.01	1.07	1.08	0.84	0.91
Dimethylglycine	ME829643	0.78	0.85	0.97	0.96	1.07	1.08	0.86	1.07
L-Phenylalanine	ME829683	0.68	0.76	0.95	0.91	1.13	1.11	0.69	1.09
L-Serine	ME829644	0.72	0.84	0.93	0.97	1.11	1.07	0.64	1.19
Melatonin	ME829703	0.66	0.65	0.82	0.92	1.19	1.15	0.66	1.00
Carnosine	ME829735	0.66	0.83	0.86	0.97	1.10	1.13	0.53	0.98
5-Aminopentanoic acid	ME829648	0.71	0.79	0.84	0.95	1.15	1.09	0.64	0.85
L-Glycine	ME829635	0.69	0.84	0.95	0.97	1.12	1.04	0.69	0.95
Choline	ME829642	0.83	0.93	1.14	0.87	1.06	1.02	0.67	0.97
Trimethylamine-N-oxide	ME829636	0.74	0.92	1.22	1.08	1.05	0.96	0.74	0.91
L-Homocysteine	ME829669	0.91	0.93	0.95	0.67	1.13	1.03	0.62	0.98
Uridine	ME829707	1.01	1.05	1.06	0.79	1.04	0.96	0.85	0.83
L-Methionine	ME829677	0.71	0.85	0.84	0.44	1.17	1.14	0.78	1.28
N-Acetylputrescine	ME829659	0.68	0.71	1.08	0.60	1.12	1.26	0.80	0.82
Creatine	ME829661	0.34	0.91	0.94	0.83	0.85	1.58	0.34	0.61
4-Trimethylammoniobutanoate	ME829726	0.46	1.18	0.90	0.96	1.10	0.79	0.47	0.60
5-Oxoproline	ME829657	0.63	0.78	0.83	0.86	1.16	1.11	0.69	0.39
L-Pipecolate	ME829658	0.39	0.74	0.67	1.05	1.13	1.19	0.83	0.54
Hydroxyproline	ME829662	0.34	0.62	0.38	1.25	1.25	1.17	0.42	0.35
L-Valine	ME829650	0.47	0.96	0.55	1.28	1.10	1.02	0.42	0.64
Sarcosine	ME829638	0.81	1.16	0.56	1.06	0.94	1.06	1.10	0.52
Acetylcholine	ME829725	0.99	1.00	0.76	1.01	0.99	1.08	0.94	NA
Spermine	ME829695	0.77	0.66	0.67	0.93	1.15	1.05	1.03	NA
3-Aminoisobutyric acid	ME829641	1.71	0.82	0.70	0.78	1.20	1.00	0.73	0.79
Adenosine	ME829708	1.37	0.67	0.52	0.89	1.22	1.05	1.54	0.62
Spermidine	ME829673	1.29	0.62	0.70	1.18	1.13	1.12	1.22	0.71
Serotonin	ME829722	2.25	1.14	1.71	1.15	0.74	0.65	3.46	0.72
L-Asparagine	ME829667	1.74	2.36	2.80	1.98	0.12	0.13	1.93	1.15
5-Aminolevulinate	ME829663	1.57	1.56	1.44	1.63	0.56	0.68	2.19	0.95
1-Methyladenosine	ME829720	1.96	1.96	1.88	1.65	0.41	0.40	1.97	0.90
L-Glutamine	ME829674	1.79	1.71	1.80	1.35	0.36	0.91	1.82	0.77
L-Cystine	ME829704	1.52	1.83	2.63	0.38	0.57	0.55	1.74	0.41
Nicotinamide	ME829655	1.56	1.08	1.56	0.88	0.95	0.74	1.86	0.68
alpha-Tocopherol	ME829716	1.85	1.75	1.71	0.41	0.69	0.68	1.53	0.38
L-Cysteine	ME829654	1.47	1.43	2.08	0.89	0.48	0.53	1.39	0.82
Cys-Gly	ME829719	1.21	1.21	1.08	0.57	0.67	0.58	0.89	NA
Cytidine	ME829705	0.84	1.55	2.20	1.18	0.65	0.71	0.61	0.76
Taurine	ME829656	0.95	1.21	1.69	0.78	0.94	0.77	1.00	0.92

Factors:

F1	Clinical group:CCP-RA \| Sample source:blood
F2	Clinical group:health \| Sample source:blood
F3	Clinical group:OA \| Sample source:blood
F4	Clinical group:pre-RA \| Sample source:blood
F5	Clinical group:RA-follow \| Sample source:blood
F6	Clinical group:RA \| Sample source:blood
F7	Clinical group:RF-RA \| Sample source:blood
F8	Clinical group:- \| Sample source:blood

Data matrix