Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003286)

(Analysis AN005383)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12	F13	F14	F15	F16	F17	F18	F19	F20	F21	F22	F23	F24	F25	F26	F27
Pyruvate	ME862323	2.93	1.10	0.68	2.00	1.22	0.98	3.34	1.19	2.10	0.19	0.66	1.33	0.38	1.57	1.48	0.30	1.42	1.45	0.17	0.16	0.19	0.37	0.39	0.32	0.40	0.34	0.34
Aspartate	ME862305	1.64	1.46	0.92	3.05	1.31	2.43	2.11	2.10	2.13	0.38	0.20	0.38	0.57	0.72	0.93	1.17	0.76	0.79	0.47	0.44	0.30	0.65	0.42	0.41	0.40	0.49	0.35
Choline	ME862306	1.96	2.35	1.78	2.23	2.54	1.60	1.84	1.78	1.37	0.25	0.24	0.29	0.64	0.34	0.36	0.57	0.27	0.56	0.59	0.66	0.75	1.08	0.66	0.57	0.56	0.58	0.60
Fumarate	ME862309	NA	NA	NA	NA	NA	NA	NA	NA	NA	0.78	0.78	1.69	1.20	0.90	0.64	0.31	0.83	0.42	1.39	1.36	1.31	0.86	1.00	1.11	1.24	1.20	1.00
Serine	ME862324	0.57	0.54	0.45	1.33	0.95	1.30	1.16	1.32	1.26	0.49	0.17	0.22	1.13	0.39	0.52	1.08	0.26	1.57	1.55	1.43	1.39	1.36	2.31	0.64	0.77	1.14	1.69
Threonine	ME862325	0.54	0.95	0.59	1.15	1.20	0.59	0.84	0.78	1.01	0.64	0.28	0.69	1.44	0.19	0.33	2.16	0.18	0.35	1.65	1.42	1.58	1.55	1.11	1.32	1.66	1.48	1.30
Glycine	ME862313	0.72	0.88	0.65	1.91	1.60	1.59	1.27	1.34	1.37	0.62	0.30	1.08	1.89	0.30	0.73	1.66	0.82	1.05	0.49	0.65	0.56	0.89	0.48	0.61	0.67	1.57	1.31
Glutamate	ME862311	0.46	0.53	0.52	1.27	1.56	1.41	1.15	1.11	0.60	0.84	0.76	1.55	1.00	1.42	1.87	1.17	1.36	0.88	0.82	0.86	0.90	0.95	1.06	0.79	0.61	0.66	0.88
Arginine	ME862304	0.79	1.80	0.72	1.10	1.44	1.23	1.44	1.58	0.94	0.36	0.32	0.49	1.36	1.08	1.32	1.22	1.28	0.73	0.93	0.83	0.83	0.93	0.99	0.82	1.03	0.78	0.66
Cystine	ME862307	1.25	1.29	1.19	1.45	1.00	1.10	1.58	1.03	1.08	0.72	0.48	1.32	1.35	0.74	1.39	1.48	0.71	0.93	0.73	0.83	0.69	0.87	0.99	0.65	0.69	0.62	0.84
Methionine	ME862319	2.14	1.84	0.38	0.97	1.12	0.84	0.63	0.85	0.78	0.84	0.79	1.09	0.83	0.81	0.82	1.37	0.93	0.94	1.25	0.96	1.01	1.10	1.01	0.81	1.07	0.96	0.84
myo-Inositol	ME862329	0.87	1.35	0.85	0.59	1.03	1.04	1.04	1.16	1.06	0.94	0.40	0.73	1.08	0.61	0.75	0.70	0.53	0.60	1.45	1.50	0.98	1.31	1.22	1.20	1.16	1.24	1.62
Tryptophan	ME862326	0.98	1.28	0.71	0.95	1.15	0.65	0.90	0.65	0.71	1.49	1.45	1.13	0.85	0.89	0.80	1.08	0.71	0.88	1.07	0.96	1.36	1.04	1.24	1.00	1.03	1.16	0.88
Valine	ME862328	1.56	1.50	1.37	0.85	0.69	0.55	0.65	0.62	0.68	1.25	0.71	1.08	1.11	0.88	0.86	1.10	0.88	1.24	1.19	1.00	1.07	1.15	1.12	0.97	1.02	0.96	0.93
Glucose	ME862310	1.00	0.76	0.98	0.83	0.65	0.89	0.78	0.66	0.76	1.10	0.99	1.08	1.09	1.04	1.09	1.03	1.10	1.06	1.12	1.13	1.13	1.13	1.12	1.13	1.09	1.12	1.14
Phenylalanine	ME862321	0.80	1.37	1.12	0.98	1.07	0.93	0.73	0.92	0.70	1.12	0.84	1.05	0.96	0.93	1.03	1.25	0.90	1.19	1.13	1.04	1.05	1.08	1.09	0.91	0.96	0.83	1.02
Glutamine	ME862312	0.54	0.32	0.22	0.95	0.26	0.39	1.13	0.53	1.05	1.39	1.39	0.98	1.26	0.95	1.22	1.36	1.05	1.33	1.23	1.20	1.15	1.22	1.27	1.07	1.05	1.21	1.27
Nicotinurate	ME862320	0.56	0.70	0.26	0.90	0.54	0.91	0.63	0.73	0.48	1.63	0.94	1.51	1.09	1.15	1.46	1.21	1.03	1.19	1.12	1.28	1.10	1.25	1.17	1.08	1.02	1.10	0.95
Lysine	ME862318	0.42	0.46	0.54	0.85	0.73	0.56	0.86	1.12	0.74	1.03	0.78	0.86	1.10	0.92	1.27	1.37	1.08	0.81	1.43	1.31	1.30	1.21	1.23	1.20	1.27	1.37	1.20
Histidine	ME862314	0.73	0.67	0.63	0.52	0.73	0.56	0.70	0.66	0.63	0.94	0.62	1.31	1.18	0.99	1.22	1.40	1.19	1.38	1.31	0.98	1.21	1.39	1.37	1.16	1.28	1.06	1.20
Isoleucine	ME862315	0.46	0.70	0.51	0.92	0.63	0.98	0.77	0.82	0.86	1.08	0.85	0.85	1.20	0.90	1.11	1.41	1.07	1.36	1.31	1.14	1.21	1.22	1.33	1.07	1.21	1.03	1.00
Pyroglutamate	ME862322	0.69	0.72	1.50	0.82	1.04	1.26	1.27	1.33	0.72	0.86	0.80	0.86	0.95	0.98	1.05	1.00	1.16	1.05	1.16	0.98	1.02	0.86	1.20	0.77	1.06	1.03	0.88
Tyrosine	ME862327	0.52	0.62	0.40	1.13	1.37	1.35	0.92	1.27	1.00	0.92	0.60	0.90	1.13	0.89	1.01	1.35	1.07	1.33	1.09	1.05	0.99	1.07	1.14	0.96	0.97	1.01	0.96
Alanine	ME862303	0.65	0.60	0.57	1.12	1.22	1.09	1.44	1.27	1.24	1.07	0.35	1.23	0.92	1.30	0.86	0.78	1.43	0.91	0.53	0.49	0.51	1.41	1.32	1.15	1.12	1.05	1.37
Leucine	ME862317	0.87	0.78	0.74	1.05	1.15	0.74	0.76	0.82	0.89	1.09	0.80	0.85	1.15	1.12	1.27	1.33	1.20	1.35	0.55	0.54	0.52	1.39	1.33	1.06	1.31	1.22	1.12
Formate	ME862308	0.33	0.66	0.41	0.76	3.79	0.57	0.37	0.47	0.56	2.71	0.56	1.64	0.65	1.94	2.09	1.15	2.19	1.99	0.52	0.40	0.48	0.44	0.55	0.43	0.46	0.41	0.46
Acetate	ME862302	0.37	0.76	0.72	0.63	2.37	2.38	1.03	2.53	1.97	0.24	0.53	1.74	0.45	2.17	1.94	0.82	2.92	1.27	0.08	0.07	0.10	0.32	0.31	0.25	0.30	0.34	0.38
Lactate	ME862316	0.31	0.44	0.29	0.72	1.88	1.72	0.84	1.23	0.93	0.51	0.55	0.62	0.95	2.54	2.52	0.75	2.52	0.65	0.78	0.75	0.76	0.79	0.85	0.79	0.78	0.73	0.80

Factors:

F1	Sample source:Non-small cell lung cancer cells \| Cell line:A549 \| Culture Type:Direct Co-culture \| Immune checkpoint inhibitor:Ipilimumab
F2	Sample source:Non-small cell lung cancer cells \| Cell line:A549 \| Culture Type:Direct Co-culture \| Immune checkpoint inhibitor:Nivolumab
F3	Sample source:Non-small cell lung cancer cells \| Cell line:A549 \| Culture Type:Direct Co-culture \| Immune checkpoint inhibitor:No treatment
F4	Sample source:Non-small cell lung cancer cells \| Cell line:A549 \| Culture Type:Indirect Co-culture \| Immune checkpoint inhibitor:Ipilimumab
F5	Sample source:Non-small cell lung cancer cells \| Cell line:A549 \| Culture Type:Indirect Co-culture \| Immune checkpoint inhibitor:Nivolumab
F6	Sample source:Non-small cell lung cancer cells \| Cell line:A549 \| Culture Type:Indirect Co-culture \| Immune checkpoint inhibitor:No treatment
F7	Sample source:Non-small cell lung cancer cells \| Cell line:A549 \| Culture Type:Monoculture \| Immune checkpoint inhibitor:Ipilimumab
F8	Sample source:Non-small cell lung cancer cells \| Cell line:A549 \| Culture Type:Monoculture \| Immune checkpoint inhibitor:Nivolumab
F9	Sample source:Non-small cell lung cancer cells \| Cell line:A549 \| Culture Type:Monoculture \| Immune checkpoint inhibitor:No treatment
F10	Sample source:Non-small cell lung cancer cells \| Cell line:H292 \| Culture Type:Direct Co-culture \| Immune checkpoint inhibitor:Ipilimumab
F11	Sample source:Non-small cell lung cancer cells \| Cell line:H292 \| Culture Type:Direct Co-culture \| Immune checkpoint inhibitor:Nivolumab
F12	Sample source:Non-small cell lung cancer cells \| Cell line:H292 \| Culture Type:Direct Co-culture \| Immune checkpoint inhibitor:No treatment
F13	Sample source:Non-small cell lung cancer cells \| Cell line:H292 \| Culture Type:Indirect Co-culture \| Immune checkpoint inhibitor:Ipilimumab
F14	Sample source:Non-small cell lung cancer cells \| Cell line:H292 \| Culture Type:Indirect Co-culture \| Immune checkpoint inhibitor:Nivolumab
F15	Sample source:Non-small cell lung cancer cells \| Cell line:H292 \| Culture Type:Indirect Co-culture \| Immune checkpoint inhibitor:No treatment
F16	Sample source:Non-small cell lung cancer cells \| Cell line:H292 \| Culture Type:Monoculture \| Immune checkpoint inhibitor:Ipilimumab
F17	Sample source:Non-small cell lung cancer cells \| Cell line:H292 \| Culture Type:Monoculture \| Immune checkpoint inhibitor:Nivolumab
F18	Sample source:Non-small cell lung cancer cells \| Cell line:H292 \| Culture Type:Monoculture \| Immune checkpoint inhibitor:No treatment
F19	Sample source:Non-small cell lung cancer cells \| Cell line:PC-9 \| Culture Type:Direct Co-culture \| Immune checkpoint inhibitor:Ipilimumab
F20	Sample source:Non-small cell lung cancer cells \| Cell line:PC-9 \| Culture Type:Direct Co-culture \| Immune checkpoint inhibitor:Nivolumab
F21	Sample source:Non-small cell lung cancer cells \| Cell line:PC-9 \| Culture Type:Direct Co-culture \| Immune checkpoint inhibitor:No treatment
F22	Sample source:Non-small cell lung cancer cells \| Cell line:PC-9 \| Culture Type:Indirect Co-culture \| Immune checkpoint inhibitor:Ipilimumab
F23	Sample source:Non-small cell lung cancer cells \| Cell line:PC-9 \| Culture Type:Indirect Co-culture \| Immune checkpoint inhibitor:Nivolumab
F24	Sample source:Non-small cell lung cancer cells \| Cell line:PC-9 \| Culture Type:Indirect Co-culture \| Immune checkpoint inhibitor:No treatment
F25	Sample source:Non-small cell lung cancer cells \| Cell line:PC-9 \| Culture Type:Monoculture \| Immune checkpoint inhibitor:Ipilimumab
F26	Sample source:Non-small cell lung cancer cells \| Cell line:PC-9 \| Culture Type:Monoculture \| Immune checkpoint inhibitor:Nivolumab
F27	Sample source:Non-small cell lung cancer cells \| Cell line:PC-9 \| Culture Type:Monoculture \| Immune checkpoint inhibitor:No treatment

Data matrix