Clustering data with hclust algorithm for (Study ST003315)

(Analysis AN005428)
MetaboliteStructureF1F2F3F4F5F6F7F8F9F10F11F12F13F14F15F16F17F18F19F20F21F22F23F24F25F26F27F28F29F30F31F32F33F34F35F36F37F38F39F40F41F42
InosineME8696600.780.600.400.350.430.530.411.061.211.190.340.610.560.220.490.360.720.920.490.480.820.560.290.480.522.730.200.733.441.280.360.620.601.200.545.010.510.4826.291.850.140.42
4-PyridoxateME8696660.074.940.179.480.271.430.102.020.781.590.190.190.140.250.400.270.830.130.980.140.060.080.110.050.130.160.041.270.192.700.770.060.320.050.050.160.110.120.240.110.720.48
MannitolME8696747.500.590.520.620.560.440.310.340.491.110.440.620.411.150.740.402.600.391.250.710.670.550.290.250.953.060.820.370.300.430.410.410.511.421.980.510.390.330.350.370.857.09
ThymidineME8696581.550.953.770.680.780.800.760.940.970.820.740.760.870.760.770.880.850.781.030.781.011.273.777.030.610.900.700.940.681.081.000.920.461.161.080.761.080.850.790.800.570.61
3-SulfocatecholME8696930.511.000.211.410.570.750.501.020.650.451.060.781.091.281.422.280.491.730.992.060.490.350.480.340.801.140.171.561.870.940.230.161.840.980.611.620.180.141.092.103.263.90
Dodecanoic acid (lauric acid)ME8697030.670.630.640.660.980.480.590.982.650.483.050.841.800.451.081.001.010.630.790.440.781.131.150.590.450.940.420.991.440.780.410.201.050.590.731.530.240.431.853.161.140.90
Tetradecanoic acid (myristic acid)ME8697041.020.820.881.051.270.670.940.921.200.581.360.861.180.581.602.160.691.090.730.591.011.170.911.130.511.210.551.191.341.020.450.391.241.781.071.840.500.962.091.990.780.97
Hexadecenoic acid (Palmitoleic acid)ME8697080.670.460.880.891.300.601.121.160.950.581.340.821.100.551.813.410.730.890.850.470.931.121.171.560.410.960.920.962.080.940.230.230.912.131.000.990.791.262.992.360.631.05
Tetradecenoic acid (myristoleic acid)ME8697070.690.530.990.741.260.591.321.020.900.491.360.740.770.352.213.490.620.920.680.370.911.330.941.140.641.690.781.141.801.080.200.141.261.640.941.601.040.663.523.090.871.03
Decanoic acid (caprate)ME8697021.281.190.800.831.410.480.570.940.821.100.751.120.680.802.161.210.971.150.680.881.000.520.580.440.732.480.491.670.950.870.480.310.610.720.883.440.361.760.851.591.120.96
Octanoic acid (caprylate)ME8697011.401.290.470.781.230.850.471.170.723.760.821.360.590.831.540.581.020.930.620.980.750.420.500.350.641.500.851.381.060.790.700.520.710.600.682.830.571.250.480.980.960.87
N-AcetylornithineME8696912.041.170.511.400.910.910.610.961.230.940.731.201.030.960.721.181.420.371.590.730.170.212.630.822.002.000.320.620.640.420.600.760.680.420.190.761.320.370.500.551.120.55
a-Linolenic acid (Octadecatrienoic acid)ME8697110.530.950.711.962.640.481.170.792.081.950.900.800.810.521.081.150.620.780.830.410.550.990.771.100.460.740.720.781.121.000.790.350.731.430.630.762.832.191.132.190.830.61
2^,3^-Cyclic CMPME8696641.010.811.580.761.080.920.720.780.891.170.821.260.640.840.861.330.812.280.501.962.870.640.460.380.430.890.611.120.781.220.601.790.560.611.191.891.121.411.321.631.040.50
glutamateME8696550.981.071.350.980.910.800.721.201.231.200.820.790.940.740.820.840.751.140.790.752.412.390.841.210.531.180.721.380.791.900.970.780.502.051.771.060.480.551.371.821.161.03
MaltoseME8696730.951.060.851.160.890.810.811.510.730.910.870.870.991.080.900.940.880.771.141.340.923.610.840.851.000.880.411.000.591.321.731.520.841.470.860.510.450.460.762.070.630.63
5-HydroxyindoleacetateME8696950.820.841.161.121.220.990.821.171.050.861.300.881.051.061.171.470.850.890.741.351.101.450.880.700.761.090.360.870.481.090.820.220.80NA0.340.671.173.510.890.621.271.10
PantothenolME8696920.531.531.251.630.511.430.671.730.841.610.661.030.760.951.180.731.170.431.510.521.100.740.670.400.330.530.591.650.851.510.621.010.980.240.100.740.310.741.331.270.610.59
(R)-S-LactoylglutathioneME8696941.201.151.301.531.351.070.940.770.950.301.121.520.881.381.001.101.180.570.831.360.971.170.300.780.880.620.991.610.961.000.210.120.160.430.201.390.360.640.410.530.310.65
BilirubinME8697181.010.861.410.890.781.451.280.981.292.320.691.090.830.810.921.500.690.690.830.740.620.320.480.740.950.640.791.231.441.130.600.901.111.081.671.040.290.711.872.210.651.23
HypoxanthineME8696611.110.761.240.900.850.720.951.001.051.510.770.840.780.800.740.791.230.771.100.951.201.240.780.510.721.830.520.891.891.250.750.781.150.881.251.821.000.663.411.441.190.97
MalateME8696800.630.891.010.951.070.841.190.781.571.680.881.041.021.001.110.960.700.890.920.981.091.171.040.600.970.600.791.150.770.901.501.401.052.672.530.840.930.910.940.761.300.84
PyruvateME8696711.321.071.340.671.180.951.020.881.401.051.051.051.090.771.160.870.751.531.011.101.131.810.590.520.580.630.390.960.301.561.501.200.802.061.410.730.760.650.540.180.400.40
Docosahexaenoic acidME8697130.661.650.511.440.740.730.950.831.171.091.041.020.920.790.790.942.070.741.290.420.640.660.780.930.981.130.800.971.420.650.440.301.010.940.761.321.150.731.460.950.840.90
Eicosapentaenoic acidME8697150.521.710.631.110.900.700.980.851.351.360.900.640.920.570.901.142.030.701.880.390.520.450.450.510.891.020.670.831.260.740.250.171.160.740.660.810.710.861.431.122.062.31
alpha-D-Ribose 1-phosphateME8696821.001.041.541.171.090.790.890.910.751.340.850.720.710.881.151.131.070.661.451.011.222.090.660.610.720.760.661.120.720.810.600.780.880.730.841.161.291.491.751.611.931.95
2-OxoglutaramateME8696780.890.951.121.071.321.101.041.060.571.640.751.250.791.030.951.631.030.760.791.001.120.950.681.041.060.820.600.970.260.960.950.862.050.490.570.961.351.300.980.361.700.97
D-RhamnoseME8696761.150.871.511.071.181.030.961.160.630.641.020.930.991.061.151.070.791.270.761.081.580.970.810.561.091.150.710.890.680.911.581.502.020.380.221.420.841.201.070.940.590.82
S-Glutathionyl-L-cysteineME8696840.800.770.911.130.861.021.410.941.231.590.890.890.890.910.821.350.921.271.041.000.831.091.031.481.721.661.070.750.870.910.411.011.380.080.060.950.631.130.741.000.641.54
DiphosphateME8696680.321.090.700.511.171.031.341.401.140.730.661.221.071.580.920.960.850.831.100.900.070.821.202.221.151.150.800.780.630.680.480.781.510.640.520.451.450.930.512.201.171.06
D-Glyceraldehyde 3-phosphate/Glycerone phosphateME8696700.720.801.150.830.851.220.721.140.940.701.041.431.181.020.850.940.971.061.061.070.710.980.971.291.651.570.400.691.200.690.701.081.200.350.670.871.110.700.921.460.670.97
PhosphateME8696670.721.030.980.741.121.011.131.121.000.880.861.030.931.190.951.020.970.930.970.980.500.951.231.271.151.150.860.841.010.930.621.071.410.781.060.741.391.130.871.741.161.10
Dodecanedioic acidME8697140.830.880.911.220.870.930.801.051.170.571.111.090.921.161.060.851.011.091.020.890.870.911.210.901.051.330.740.980.800.841.000.881.200.840.660.991.752.461.281.130.970.57
(7Z-10Z-13Z-16Z-19Z)-Docosa-7-10-13-16-19-pentaenoic acidME8697170.610.930.941.120.950.651.320.961.421.391.190.901.110.490.981.450.871.121.040.470.641.001.321.560.740.970.701.041.380.900.420.350.641.491.131.091.961.921.851.090.691.73
Arachidonic acid (Eicosatetraenoic acid)ME8697120.950.650.941.021.120.881.110.840.850.881.181.071.280.701.091.630.761.220.880.850.851.000.841.410.580.770.671.091.841.040.590.510.571.511.220.842.072.041.971.640.670.69
Linoleic acid ((9Z,12Z)-Octadecadienoic acid)ME8697100.830.900.841.221.000.780.851.081.010.891.240.951.140.681.301.330.671.120.900.750.871.281.351.130.890.950.761.061.531.020.970.460.841.811.140.992.371.991.211.540.760.74
Octadecanoic acid (stearic acid)ME8697060.921.000.871.270.930.960.900.921.170.911.100.961.100.780.951.260.721.210.910.701.181.241.391.390.711.071.241.211.270.971.150.720.911.340.881.241.281.241.091.190.631.36
Sphinganine 1-phosphateME8696990.901.010.951.261.111.230.800.871.061.041.201.091.140.620.901.130.780.970.850.770.971.201.161.330.681.000.911.401.260.980.850.770.800.910.851.121.111.390.851.350.611.32
(8Z-11Z-14Z)-Icosatrienoic acidME8697160.700.791.271.081.100.731.471.351.130.951.020.941.010.530.921.500.641.090.830.710.720.981.081.790.510.880.641.231.571.190.800.820.581.500.951.041.051.911.251.540.791.27
Hexadecanoic acid (palmitic acid)ME8697050.910.880.891.081.070.800.951.021.050.971.080.941.140.781.051.600.771.080.860.830.961.131.181.200.890.960.921.011.431.050.970.681.071.681.151.151.291.461.481.071.070.94
Octadecenoic acid (Oleic acid)ME8697090.780.710.921.131.060.811.081.021.050.891.180.971.130.721.161.590.730.900.830.700.891.111.221.610.941.100.800.991.591.120.720.491.001.641.271.111.271.791.641.630.761.00
TetrahydrofolateME8696881.061.641.130.960.650.830.981.051.110.800.720.671.130.740.800.601.290.931.571.020.690.940.430.730.630.751.040.801.291.210.870.901.051.261.000.861.901.011.041.580.781.67
Ethanolamine phosphateME8696970.991.150.581.211.051.110.750.790.850.890.881.400.800.791.100.550.841.600.691.720.810.350.420.580.951.081.141.001.020.921.381.151.140.651.152.050.961.200.961.361.210.95
dTMPME8696570.860.611.060.881.331.030.980.881.140.990.821.021.261.171.300.930.871.080.921.581.401.190.760.630.810.871.290.861.550.901.251.130.690.820.931.650.390.491.340.360.640.58
Sphingosine 1-phosphateME8696980.990.660.721.360.960.870.961.071.440.781.020.900.810.760.910.710.831.481.271.320.560.721.181.050.640.851.341.141.391.001.291.070.740.701.291.150.680.971.190.751.921.32
asparagineME8696530.801.090.861.260.831.190.731.011.430.840.671.240.821.321.510.800.911.180.921.210.770.680.820.701.131.141.010.790.830.911.141.011.111.081.121.100.981.130.780.831.150.77
(5-L-Glutamyl)-L-glutamineME8696871.121.111.081.211.100.791.260.801.051.130.920.960.900.961.160.890.791.191.051.210.810.680.570.651.051.071.240.831.250.970.801.141.440.900.761.220.881.000.890.871.501.08
Heptanoic acidME8697001.071.081.081.110.961.010.860.850.881.080.831.021.210.980.990.780.921.130.921.101.370.880.711.081.071.471.081.071.241.030.851.450.910.900.940.870.670.951.130.771.081.26
5-6-DihydrothymineME8696651.250.831.421.021.010.960.901.150.940.980.880.911.121.011.320.900.770.810.861.070.900.720.640.711.291.231.161.090.801.270.940.991.390.990.791.060.821.110.941.011.231.37
GlycolateME8696901.150.891.271.010.991.010.821.040.940.950.990.881.071.081.100.800.991.091.081.270.870.670.760.731.231.010.840.951.100.991.071.091.120.940.840.911.140.831.150.830.981.03
UDPME8696590.931.001.101.270.910.920.991.070.981.020.790.871.071.021.200.830.971.071.070.971.120.860.891.111.181.210.890.701.191.031.250.781.081.080.891.120.940.891.200.921.081.33
2-Hydroxyglutarate/CitramalateME8696810.971.031.351.050.930.921.130.930.941.040.891.040.981.150.850.901.080.831.260.740.640.620.780.431.141.130.811.261.061.180.681.041.150.570.521.090.640.751.071.181.191.15
DehydroascorbateME8696851.030.910.941.271.001.240.761.080.931.030.770.960.780.950.730.741.040.871.480.900.781.020.850.561.551.150.860.890.870.891.141.071.370.730.911.090.930.781.570.881.061.09
5-HydroxyisourateME8696621.080.880.951.231.060.830.980.991.111.231.000.811.040.951.110.710.921.240.911.201.251.220.970.711.031.151.020.731.041.261.180.700.801.300.991.111.830.851.110.341.070.95
aspartateME8696540.931.021.211.030.861.001.110.911.131.250.700.890.891.010.951.470.851.230.900.991.271.560.840.940.780.910.711.040.851.420.661.000.791.041.270.891.301.301.131.221.511.24
CitrateME8696770.790.980.901.061.140.881.021.001.191.241.121.210.920.931.010.820.721.060.890.810.910.911.530.991.030.960.770.980.911.101.131.101.071.371.380.911.261.121.161.030.890.87
D-RiboseME8696751.101.201.140.890.841.040.831.181.000.880.890.961.000.930.901.010.980.920.841.051.281.221.090.940.801.021.051.050.931.231.121.111.001.271.360.971.191.020.871.001.210.86
1-4-beta-D-XylanME8696891.091.211.210.860.891.030.841.090.990.880.940.891.020.960.871.051.010.960.850.991.191.311.230.920.791.030.991.120.761.281.191.010.971.491.290.851.451.021.091.030.720.87
D-GlucoseME8696691.141.221.200.870.881.050.851.121.120.970.900.901.030.960.861.050.970.950.791.021.241.281.110.910.701.041.001.090.781.221.121.120.921.531.350.941.251.050.991.020.730.93
cystineME8696561.090.961.281.090.961.070.921.111.020.990.810.930.930.921.241.060.990.730.990.950.880.940.921.131.091.130.830.981.071.051.221.220.640.970.740.781.461.411.451.031.071.07
UrateME8696630.971.111.341.121.150.981.040.960.941.121.140.890.950.860.930.860.941.070.881.190.940.900.680.600.851.000.781.220.761.330.831.110.820.810.910.701.401.211.151.090.860.84
Glycerol 3-phosphateME8696960.580.890.991.151.140.951.230.931.021.370.730.921.021.141.411.280.701.800.871.470.760.850.760.751.111.460.790.880.780.940.601.001.300.830.901.230.650.900.630.560.960.82
SuccinateME8696791.120.801.191.051.421.031.150.931.100.770.951.050.861.141.350.810.920.970.941.030.921.330.750.500.970.880.680.890.740.940.690.952.030.721.201.020.920.940.870.601.150.85
gamma-L-Glutamyl-D-alanineME8696860.811.030.990.891.041.110.960.891.271.190.870.830.970.851.150.980.761.220.911.391.310.760.791.021.091.091.110.800.841.521.050.841.631.601.001.180.690.730.640.731.950.63
5-OxoprolineME8696830.720.971.011.080.990.901.090.761.221.020.911.100.940.930.820.830.851.590.741.050.860.790.880.700.770.911.481.211.301.371.111.291.311.141.411.320.640.651.361.361.370.91
LactateME8696720.870.931.151.101.040.911.220.811.641.450.910.880.910.751.000.770.771.410.971.051.271.280.760.570.790.761.091.120.961.391.321.330.821.891.650.910.510.481.160.850.850.62

Factors:

F1Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :High BL, High W5 | PEPI Score :>0 | Visit :Baseline | Arm :Combination
F2Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :High BL, High W5 | PEPI Score :>0 | Visit :Baseline | Arm :Fulvestrant
F3Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :High BL, High W5 | PEPI Score :>0 | Visit :C4D1 | Arm :Combination
F4Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :High BL, High W5 | PEPI Score :>0 | Visit :C4D1 | Arm :Fulvestrant
F5Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :High BL, Low W5 | PEPI Score :>0 | Visit :Baseline | Arm :Combination
F6Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :High BL, Low W5 | PEPI Score :>0 | Visit :Baseline | Arm :Fulvestrant
F7Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :High BL, Low W5 | PEPI Score :>0 | Visit :C4D1 | Arm :Combination
F8Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :High BL, Low W5 | PEPI Score :>0 | Visit :C4D1 | Arm :Fulvestrant
F9Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :0 | Visit :Baseline | Arm :Combination
F10Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :0 | Visit :C4D1 | Arm :Combination
F11Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :>0 | Visit :Baseline | Arm :Combination
F12Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :>0 | Visit :Baseline | Arm :Fulvestrant
F13Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :>0 | Visit :C4D1 | Arm :Combination
F14Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :>0 | Visit :C4D1 | Arm :Fulvestrant
F15Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :not available | PEPI Score :0 | Visit :Baseline | Arm :Combination
F16Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :not available | PEPI Score :0 | Visit :C4D1 | Arm :Combination
F17Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :not available | PEPI Score :>0 | Visit :Baseline | Arm :Combination
F18Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :not available | PEPI Score :>0 | Visit :Baseline | Arm :Fulvestrant
F19Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :not available | PEPI Score :>0 | Visit :C4D1 | Arm :Combination
F20Sample source:Plasma | Histology :Ductal | Lab Ki67 Group :not available | PEPI Score :>0 | Visit :C4D1 | Arm :Fulvestrant
F21Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :High BL, High W5 | PEPI Score :>0 | Visit :Baseline | Arm :Combination
F22Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :High BL, High W5 | PEPI Score :>0 | Visit :C4D1 | Arm :Combination
F23Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :High BL, Low W5 | PEPI Score :0 | Visit :Baseline | Arm :Combination
F24Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :High BL, Low W5 | PEPI Score :0 | Visit :C4D1 | Arm :Combination
F25Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :0 | Visit :Baseline | Arm :Fulvestrant
F26Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :0 | Visit :C4D1 | Arm :Fulvestrant
F27Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :>0 | Visit :Baseline | Arm :Combination
F28Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :>0 | Visit :Baseline | Arm :Fulvestrant
F29Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :>0 | Visit :C4D1 | Arm :Combination
F30Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :>0 | Visit :C4D1 | Arm :Fulvestrant
F31Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :not available | PEPI Score :0 | Visit :Baseline | Arm :Combination
F32Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :not available | PEPI Score :0 | Visit :C4D1 | Arm :Combination
F33Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :not available | PEPI Score :>0 | Visit :Baseline | Arm :Combination
F34Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :not available | PEPI Score :>0 | Visit :Baseline | Arm :Fulvestrant
F35Sample source:Plasma | Histology :Lobular | Lab Ki67 Group :not available | PEPI Score :>0 | Visit :C4D1 | Arm :Fulvestrant
F36Sample source:Plasma | Histology :not available | Lab Ki67 Group :not available | PEPI Score :not available | Visit :Baseline | Arm :not enrolled, baseline only
F37Sample source:Plasma | Histology :Other | Lab Ki67 Group :High BL, High W5 | PEPI Score :>0 | Visit :Baseline | Arm :Combination
F38Sample source:Plasma | Histology :Other | Lab Ki67 Group :High BL, High W5 | PEPI Score :>0 | Visit :C4D1 | Arm :Combination
F39Sample source:Plasma | Histology :Other | Lab Ki67 Group :High BL, Low W5 | PEPI Score :>0 | Visit :Baseline | Arm :Combination
F40Sample source:Plasma | Histology :Other | Lab Ki67 Group :High BL, Low W5 | PEPI Score :>0 | Visit :C4D1 | Arm :Combination
F41Sample source:Plasma | Histology :Other | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :0 | Visit :Baseline | Arm :Combination
F42Sample source:Plasma | Histology :Other | Lab Ki67 Group :Low BL, Low W5 | PEPI Score :0 | Visit :C4D1 | Arm :Combination
Data matrix
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