Clustering data with hclust algorithm for (Study ST003405)
HILIC NEGATIVE ION MODE (Analysis AN005589)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cystathionine | ME891613 | 0.92 | 0.90 | 0.88 | 0.90 | 0.89 | 1.10 | 1.10 | 1.09 | 1.11 | 1.11 |
| Saccharopine | ME891632 | 0.95 | 0.91 | 0.91 | 0.94 | 0.91 | 1.08 | 1.07 | 1.09 | 1.08 | 1.07 |
| Orotate | ME891552 | 0.95 | 0.95 | 1.07 | 1.04 | 0.99 | 0.94 | 0.95 | 1.07 | 1.04 | 1.00 |
| Phosphoethanolamine | ME891539 | 0.97 | 0.99 | 1.12 | 1.00 | 1.04 | 0.92 | 0.96 | 1.06 | 0.96 | 0.99 |
| Aminoadipic acid | ME891561 | 0.97 | 0.95 | 0.93 | 0.95 | 0.95 | 1.05 | 1.05 | 1.05 | 1.05 | 1.05 |
| Phosphoserine | ME891593 | 0.93 | 0.94 | 1.00 | 0.99 | 0.98 | 0.99 | 1.01 | 1.07 | 1.05 | 1.05 |
| Histidine | ME891553 | 1.00 | 1.00 | 0.88 | 1.00 | 1.00 | 1.01 | 1.01 | 1.03 | 1.03 | 1.05 |
| Cer(18:1;O2/16:0) | ME891664 | 0.92 | 1.04 | 1.04 | 1.05 | 0.99 | 0.97 | 0.99 | 0.98 | 1.01 | 1.00 |
| PE(16:0/18:1) | ME891673 | 0.91 | 1.03 | 1.02 | 1.02 | 1.00 | 1.00 | 1.02 | 0.99 | 1.02 | 1.01 |
| Heptanoic acid | ME891534 | 0.92 | 1.01 | 1.01 | 1.01 | 1.01 | 1.01 | 1.00 | 1.01 | 1.01 | 1.01 |
| PE(16:0/20:4) | ME891674 | 0.92 | 1.02 | 1.01 | 1.02 | 1.03 | 1.00 | 1.00 | 0.98 | 1.01 | 1.00 |
| PE(O-18:1(1Z)/20:4(5Z,8Z,11Z,14Z)) | ME891676 | 0.89 | 1.01 | 1.02 | 1.01 | 1.00 | 0.99 | 1.02 | 1.02 | 1.02 | 1.02 |
| Xanthine | ME891548 | 0.89 | 1.02 | 0.99 | 1.01 | 1.01 | 1.02 | 1.03 | 1.00 | 1.02 | 1.01 |
| CDP-ethanolamine | ME891656 | 0.99 | 1.01 | 1.04 | 1.01 | 1.03 | 0.94 | 0.98 | 1.01 | 0.99 | 1.00 |
| 3-Hydroxyphenylacetic acid | ME891549 | 1.01 | 1.03 | 1.01 | 1.03 | 1.03 | 0.96 | 1.00 | 0.97 | 0.97 | 0.97 |
| Oxalacetic acid | ME891529 | 1.03 | 1.03 | 1.02 | 1.02 | 1.03 | 0.98 | 0.96 | 0.99 | 0.97 | 0.98 |
| Erythrose 4-phosphate | ME891603 | 0.97 | 0.96 | 1.04 | 0.99 | 1.01 | 0.95 | 0.98 | 1.07 | 1.03 | 1.01 |
| Fructose-1,6-bisphosphate | ME891683 | 0.99 | 0.98 | 1.03 | 1.01 | 1.00 | 0.97 | 0.97 | 1.03 | 1.01 | 1.00 |
| N-acetylglucosamine-6-phosphate | ME891639 | 0.99 | 0.96 | 1.03 | 1.02 | 1.00 | 0.98 | 0.99 | 1.03 | 1.01 | 1.00 |
| Ophthalmic acid | ME891635 | 1.01 | 0.97 | 1.00 | 1.00 | 0.99 | 0.99 | 0.98 | 1.04 | 1.01 | 1.02 |
| Fructose 6-phosphate | ME891681 | 0.98 | 0.98 | 1.02 | 0.99 | 1.00 | 0.97 | 0.99 | 1.05 | 1.01 | 1.01 |
| Glucose 6-phosphate | ME891624 | 0.98 | 0.98 | 1.03 | 0.99 | 1.00 | 0.97 | 0.98 | 1.05 | 1.01 | 1.01 |
| 6-Phosphogluconic acid | ME891631 | 0.98 | 0.98 | 1.01 | 0.98 | 0.98 | 0.99 | 1.00 | 1.05 | 1.02 | 1.01 |
| Ribulose 5-phosphate | ME891615 | 0.98 | 0.98 | 1.00 | 1.01 | 0.99 | 0.98 | 0.99 | 1.04 | 1.02 | 1.01 |
| Sedoheptulose-7-phosphate | ME891637 | 0.97 | 0.98 | 1.00 | 1.00 | 0.99 | 0.98 | 1.00 | 1.05 | 1.03 | 1.01 |
| Adenosine phosphosulfate | ME891652 | 1.00 | 1.00 | 0.94 | 0.99 | 1.02 | 1.00 | 1.01 | 0.96 | 1.04 | 1.03 |
| Inosine-monophosphate | ME891646 | 1.03 | 1.01 | 0.98 | 1.01 | 1.02 | 1.00 | 1.01 | 0.94 | 1.00 | 0.99 |
| Thymidine monophosphate | ME891643 | 1.03 | 1.03 | 0.97 | 1.01 | 1.01 | 1.00 | 1.01 | 0.96 | 1.00 | 0.99 |
| Aconitate | ME891579 | 1.04 | 1.02 | 1.00 | 0.98 | 1.02 | 1.03 | 1.01 | 0.94 | 0.96 | 1.00 |
| Citrate | ME891601 | 1.03 | 1.01 | 1.00 | 0.98 | 1.01 | 1.02 | 1.01 | 0.96 | 0.98 | 1.00 |
| Cystine | ME891618 | 1.01 | 1.02 | 0.98 | 0.98 | 0.96 | 1.00 | 1.00 | 0.98 | 1.03 | 1.04 |
| Hydroxyphenyllactic acid | ME891586 | 0.98 | 0.98 | 0.98 | 0.99 | 0.98 | 1.00 | 1.01 | 1.02 | 1.02 | 1.02 |
| Asparagine | ME891532 | 0.98 | 0.97 | 0.97 | 0.98 | 0.98 | 1.00 | 1.01 | 1.04 | 1.03 | 1.03 |
| Gamma-glutamylcysteine | ME891621 | 0.98 | 0.99 | 0.97 | 0.98 | 0.98 | 0.99 | 1.01 | 1.04 | 1.03 | 1.04 |
| Ketoleucine | ME891533 | 0.99 | 0.98 | 0.97 | 0.98 | 0.98 | 1.01 | 1.02 | 1.02 | 1.02 | 1.02 |
| N-acetylasparthylglutamate | ME891640 | 0.99 | 0.98 | 0.96 | 0.98 | 0.98 | 1.02 | 1.03 | 1.02 | 1.03 | 1.02 |
| Leu-ala | ME891604 | 0.99 | 0.98 | 0.96 | 0.98 | 0.96 | 1.03 | 1.02 | 1.02 | 1.03 | 1.03 |
| N-acetylglutamine | ME891597 | 0.99 | 0.98 | 0.97 | 0.97 | 0.97 | 1.03 | 1.03 | 1.02 | 1.03 | 1.02 |
| N-acetylmethionine | ME891599 | 1.01 | 0.99 | 0.95 | 0.99 | 0.97 | 1.03 | 1.02 | 0.99 | 1.02 | 1.02 |
| Gamma-glutamylalanine | ME891611 | 1.01 | 0.98 | 0.95 | 0.99 | 0.98 | 1.01 | 1.00 | 1.00 | 1.03 | 1.03 |
| 2-Hydroxyglutarate | ME891545 | 1.00 | 0.98 | 0.96 | 0.98 | 0.98 | 1.03 | 1.02 | 1.00 | 1.02 | 1.01 |
| Glycine | ME891503 | 1.00 | 0.98 | 0.96 | 0.99 | 0.99 | 1.01 | 1.01 | 1.01 | 1.02 | 1.02 |
| Gly-ser | ME891559 | 1.00 | 0.98 | 0.96 | 0.98 | 0.98 | 1.02 | 1.01 | 1.01 | 1.02 | 1.02 |
| Galacturonic acid | ME891600 | 0.96 | 0.98 | 0.97 | 1.02 | 0.97 | 1.00 | 1.01 | 1.02 | 1.04 | 1.04 |
| N-acetylcysteine | ME891560 | 0.97 | 0.98 | 0.94 | 0.98 | 0.97 | 1.01 | 1.03 | 1.02 | 1.05 | 1.05 |
| Inosine | ME891629 | 0.96 | 1.00 | 1.00 | 1.01 | 1.00 | 0.96 | 1.01 | 1.01 | 1.02 | 1.02 |
| LPE(18:0/0:0) | ME891658 | 0.98 | 1.02 | 0.99 | 1.01 | 1.01 | 0.97 | 1.01 | 1.00 | 1.00 | 1.01 |
| Galactonic acid | ME891602 | 1.02 | 1.00 | 0.97 | 1.00 | 1.00 | 1.02 | 1.01 | 0.96 | 1.02 | 1.00 |
| N-acetyltaurine | ME891564 | 1.01 | 1.00 | 0.97 | 1.01 | 0.99 | 1.02 | 1.02 | 0.97 | 1.02 | 1.00 |
| Cysteic acid | ME891568 | 1.04 | 0.99 | 0.94 | 0.99 | 0.99 | 1.03 | 1.01 | 0.98 | 1.01 | 1.02 |
| Glyceraldehyde 3-p | ME891571 | 1.04 | 0.99 | 0.97 | 0.99 | 0.98 | 1.03 | 1.00 | 0.98 | 1.01 | 1.00 |
| Cyclic AMP | ME891682 | 1.01 | 0.99 | 0.97 | 1.00 | 1.03 | 1.00 | 0.97 | 0.99 | 1.01 | 1.02 |
| Caprylic acid | ME891541 | 1.00 | 1.00 | 1.01 | 0.99 | 0.98 | 0.98 | 1.03 | 1.00 | 0.99 | 1.01 |
| Dihydroorotate | ME891555 | 0.99 | 0.98 | 1.01 | 1.03 | 1.00 | 0.98 | 0.98 | 0.99 | 1.02 | 1.00 |
| Ornithine | ME891535 | 1.01 | 0.99 | 0.98 | 1.01 | 1.00 | 0.98 | 1.00 | 1.00 | 1.02 | 1.01 |
| Ribose-1-p | ME891616 | 1.00 | 0.99 | 1.00 | 1.01 | 1.00 | 0.98 | 1.00 | 1.02 | 1.02 | 0.99 |
| Uridine monophosphate | ME891644 | 1.00 | 0.99 | 0.99 | 1.01 | 1.01 | 0.98 | 1.00 | 1.01 | 1.01 | 1.00 |
| Thymine | ME891527 | 0.98 | 1.00 | 1.02 | 1.00 | 1.01 | 0.98 | 0.99 | 1.01 | 1.01 | 1.00 |
| Cytidine triphosphate | ME891660 | 1.00 | 0.99 | 1.03 | 1.00 | 1.00 | 0.98 | 0.99 | 1.01 | 1.01 | 0.99 |
| Guanosine triphosphate | ME891662 | 1.00 | 0.99 | 1.03 | 1.00 | 1.00 | 0.99 | 0.99 | 1.02 | 1.00 | 0.99 |
| Uridine triphosphate | ME891661 | 1.00 | 1.00 | 1.02 | 1.00 | 1.01 | 0.98 | 1.00 | 1.00 | 1.00 | 0.99 |
| Adenosine triphosphate | ME891663 | 1.00 | 0.99 | 1.01 | 1.00 | 1.00 | 0.99 | 0.99 | 1.01 | 1.00 | 0.99 |
| Guanosine diphosphate | ME891655 | 1.00 | 1.00 | 1.02 | 1.00 | 1.00 | 0.99 | 0.99 | 1.00 | 1.00 | 1.00 |
| N-formylmethionine | ME891580 | 0.98 | 1.01 | 1.00 | 1.00 | 1.00 | 0.99 | 1.01 | 1.00 | 1.01 | 1.00 |
| Benzoic acid | ME891526 | 0.99 | 0.99 | 1.01 | 1.00 | 1.00 | 0.99 | 1.00 | 0.99 | 1.02 | 1.01 |
| Succinylacetone | ME891556 | 0.97 | 0.99 | 1.00 | 1.00 | 1.01 | 1.00 | 1.00 | 1.00 | 1.01 | 1.01 |
| Allantoin | ME891554 | 0.99 | 1.00 | 0.96 | 1.01 | 1.00 | 1.01 | 1.01 | 0.99 | 1.02 | 1.01 |
| Arginine | ME891575 | 1.00 | 1.00 | 0.98 | 1.00 | 0.99 | 0.99 | 1.01 | 1.01 | 1.01 | 1.01 |
| Glutamine | ME891543 | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 | 0.99 | 1.00 | 1.01 | 1.01 | 1.01 |
| Phosphocreatine | ME891609 | 1.00 | 0.99 | 0.99 | 0.99 | 0.99 | 1.00 | 1.01 | 1.01 | 1.01 | 1.01 |
| Alanine | ME891506 | 1.00 | 0.99 | 0.99 | 1.00 | 0.99 | 1.01 | 1.00 | 1.00 | 1.01 | 1.01 |
| UDP-n-acetylglucosamine | ME891669 | 1.00 | 0.99 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.01 | 1.01 |
| Lysine | ME891542 | 1.01 | 0.99 | 0.97 | 1.00 | 0.99 | 0.99 | 1.01 | 1.01 | 1.02 | 1.01 |
| 3-Methylhistidine | ME891567 | 1.00 | 0.99 | 0.97 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.02 | 1.02 |
| Citrulline | ME891577 | 1.01 | 0.99 | 0.97 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.02 | 1.02 |
| Serine | ME891511 | 1.00 | 0.99 | 0.98 | 1.00 | 0.99 | 0.99 | 1.00 | 1.02 | 1.02 | 1.02 |
| N-Acetylornithine | ME891574 | 0.99 | 0.99 | 0.98 | 1.00 | 0.99 | 1.00 | 1.01 | 1.01 | 1.02 | 1.02 |
| Valine | ME891521 | 1.00 | 0.99 | 0.98 | 1.00 | 0.99 | 1.00 | 1.00 | 1.01 | 1.01 | 1.02 |
| Isoleucine | ME891679 | 1.00 | 0.99 | 0.98 | 1.00 | 0.99 | 1.00 | 1.00 | 1.01 | 1.01 | 1.01 |
| Leucine | ME891680 | 1.00 | 0.99 | 0.98 | 1.00 | 0.99 | 1.00 | 1.00 | 1.01 | 1.01 | 1.01 |
| Tyrosine | ME891585 | 1.00 | 0.99 | 0.98 | 0.99 | 0.99 | 1.00 | 1.01 | 1.01 | 1.02 | 1.02 |
| Phenylalanine | ME891562 | 1.00 | 0.99 | 0.98 | 0.99 | 0.99 | 1.00 | 1.00 | 1.01 | 1.01 | 1.02 |
| Methionine | ME891544 | 1.00 | 0.99 | 0.98 | 1.00 | 0.99 | 1.00 | 1.00 | 1.01 | 1.02 | 1.02 |
| Threonine | ME891523 | 1.00 | 0.99 | 0.98 | 0.99 | 0.99 | 1.00 | 1.00 | 1.01 | 1.02 | 1.02 |
| Tryptophan | ME891606 | 1.00 | 0.99 | 0.98 | 0.99 | 0.99 | 1.00 | 1.00 | 1.01 | 1.02 | 1.02 |
| Gly-asp | ME891598 | 1.02 | 0.99 | 0.97 | 0.99 | 0.99 | 1.01 | 1.00 | 1.00 | 1.02 | 1.01 |
| Gly-glu | ME891608 | 1.01 | 0.99 | 0.97 | 0.99 | 0.98 | 1.01 | 1.01 | 1.00 | 1.02 | 1.01 |
| Betaine | ME891522 | 1.00 | 0.99 | 0.98 | 0.99 | 0.99 | 1.01 | 1.02 | 1.00 | 1.01 | 1.02 |
| Glucosamine | ME891584 | 1.00 | 0.99 | 0.98 | 0.99 | 0.99 | 1.01 | 1.01 | 1.00 | 1.02 | 1.02 |
| NADH | ME891672 | 1.00 | 0.99 | 0.98 | 1.00 | 1.00 | 1.01 | 1.01 | 0.99 | 1.02 | 1.01 |
| Proline | ME891518 | 1.00 | 0.99 | 0.98 | 1.00 | 0.99 | 1.00 | 1.01 | 1.00 | 1.02 | 1.01 |
| L-Arabitol | ME891550 | 1.00 | 0.99 | 0.97 | 1.00 | 0.99 | 1.01 | 1.01 | 1.00 | 1.02 | 1.01 |
| N-Acetylglutamine | ME891594 | 1.01 | 0.99 | 0.97 | 1.00 | 0.99 | 1.01 | 1.01 | 0.99 | 1.02 | 1.01 |
| beta-Asp-Leu | ME891620 | 1.02 | 0.99 | 0.96 | 1.00 | 0.98 | 1.00 | 1.02 | 0.99 | 1.02 | 1.01 |
| 2-Oxoglutarate | ME891540 | 1.00 | 0.99 | 0.98 | 0.99 | 0.99 | 1.03 | 1.02 | 0.98 | 1.01 | 1.00 |
| Palmitoleic acid | ME891622 | 1.01 | 1.01 | 0.98 | 1.00 | 0.98 | 1.01 | 1.01 | 1.00 | 1.00 | 1.00 |
| Glucosamine 6-phosphate | ME891623 | 1.01 | 1.00 | 0.97 | 0.99 | 0.98 | 1.02 | 1.02 | 1.00 | 1.01 | 1.01 |
| N-acetylvaline | ME891557 | 1.00 | 1.00 | 0.97 | 1.00 | 0.98 | 1.02 | 1.01 | 0.99 | 1.01 | 1.01 |
| Indolelactic acid | ME891607 | 1.00 | 1.00 | 0.98 | 0.99 | 0.99 | 1.00 | 1.02 | 1.00 | 1.02 | 1.00 |
| 3-Hydroxyisobutyric acid | ME891515 | 1.01 | 1.00 | 0.97 | 0.99 | 0.99 | 1.01 | 1.02 | 0.99 | 1.01 | 1.00 |
| Adenine | ME891537 | 1.00 | 1.00 | 0.97 | 1.00 | 0.99 | 1.01 | 1.02 | 1.00 | 1.01 | 1.00 |
| Myoinositol | ME891589 | 1.02 | 1.00 | 0.98 | 1.00 | 1.00 | 1.00 | 1.00 | 0.97 | 1.01 | 1.01 |
| Malate | ME891538 | 1.01 | 1.00 | 0.99 | 1.00 | 1.00 | 1.01 | 1.01 | 0.98 | 1.00 | 1.00 |
| Hypotaurine | ME891512 | 1.02 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.02 | 0.97 | 1.01 | 1.00 |
| Fumaric acid | ME891519 | 1.01 | 1.00 | 0.99 | 1.01 | 1.00 | 1.01 | 1.01 | 0.97 | 1.01 | 1.00 |
| Taurine | ME891528 | 1.02 | 1.00 | 0.99 | 1.00 | 1.00 | 1.01 | 1.01 | 0.97 | 1.01 | 1.00 |
| Ascorbate | ME891581 | 1.03 | 1.01 | 0.99 | 1.00 | 1.00 | 1.01 | 1.01 | 0.96 | 1.00 | 0.99 |
| Cys-gly | ME891582 | 1.02 | 1.01 | 0.98 | 1.01 | 1.00 | 1.01 | 1.01 | 0.98 | 1.00 | 0.98 |
| S-adenosylhomocysteine | ME891649 | 1.02 | 1.01 | 0.99 | 0.99 | 1.00 | 1.01 | 1.00 | 0.99 | 1.00 | 0.99 |
| 3-Phosphoglycerate | ME891592 | 1.03 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 0.98 | 1.00 | 0.99 |
| Phosphoenolpyruvate | ME891565 | 1.03 | 1.01 | 0.99 | 1.00 | 1.00 | 1.01 | 1.00 | 0.98 | 0.99 | 0.99 |
| Linoleate | ME891634 | 1.02 | 0.99 | 0.98 | 1.01 | 0.98 | 1.01 | 1.00 | 1.01 | 0.99 | 1.00 |
| Glu-glu | ME891633 | 1.02 | 0.99 | 0.97 | 1.00 | 0.99 | 1.01 | 1.01 | 0.99 | 1.01 | 1.00 |
| ADP-glucose | ME891667 | 1.02 | 0.99 | 0.98 | 1.00 | 1.00 | 1.02 | 1.00 | 0.99 | 1.01 | 0.99 |
| Azelaic acid | ME891596 | 1.02 | 0.99 | 0.98 | 1.00 | 0.99 | 1.02 | 1.00 | 1.00 | 1.00 | 0.99 |
| Dihydroxyacetone phosphate | ME891570 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 0.99 | 0.99 | 1.01 | 1.01 | 1.01 |
| Stearic acid | ME891638 | 0.99 | 0.99 | 1.00 | 1.01 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Glycerol 3-phosphate | ME891573 | 0.99 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.01 |
| NAD | ME891671 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| NADP | ME891675 | 1.00 | 0.98 | 0.99 | 0.99 | 1.01 | 1.00 | 1.00 | 1.01 | 1.01 | 1.00 |
| UDP-glucuronic acid | ME891666 | 1.00 | 0.98 | 0.99 | 1.00 | 0.99 | 1.00 | 1.00 | 1.02 | 1.01 | 1.00 |
| Heptadecanoic acid | ME891630 | 1.01 | 1.00 | 1.00 | 1.02 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 0.99 |
| FAD | ME891677 | 1.01 | 1.00 | 0.98 | 1.00 | 1.01 | 1.01 | 0.99 | 1.00 | 1.00 | 1.01 |
| Folic acid | ME891654 | 1.00 | 1.01 | 0.99 | 1.00 | 1.00 | 0.98 | 1.01 | 0.99 | 1.00 | 1.00 |
| Nicotinamide | ME891525 | 1.00 | 1.01 | 0.99 | 1.00 | 1.00 | 0.99 | 1.02 | 0.99 | 1.00 | 1.00 |
| Propenoic acid | ME891502 | 1.01 | 1.00 | 0.99 | 1.00 | 1.00 | 0.99 | 1.01 | 0.99 | 1.01 | 1.00 |
| Pseudouridine | ME891619 | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 | 0.99 | 1.01 | 0.99 | 1.01 | 1.00 |
| Succinic acid semialdehyde | ME891510 | 1.01 | 1.01 | 0.99 | 1.00 | 1.00 | 0.99 | 1.01 | 0.99 | 1.00 | 1.00 |
| Glucose | ME891590 | 1.01 | 1.00 | 0.99 | 1.00 | 1.00 | 0.99 | 1.01 | 1.00 | 1.00 | 1.00 |
| Uracil | ME891516 | 1.01 | 1.00 | 0.99 | 1.00 | 1.00 | 0.99 | 1.01 | 0.99 | 1.00 | 1.00 |
| Hippurate | ME891583 | 1.00 | 1.01 | 0.98 | 1.00 | 1.00 | 1.00 | 1.02 | 0.99 | 1.01 | 1.00 |
| Asp-glu | ME891626 | 1.01 | 1.00 | 0.98 | 1.00 | 0.99 | 1.00 | 1.01 | 1.00 | 1.01 | 1.01 |
| Carnosine | ME891614 | 1.01 | 1.01 | 0.99 | 1.00 | 0.99 | 1.00 | 1.01 | 1.00 | 1.01 | 1.00 |
| N-acetylneuraminate | ME891641 | 1.01 | 1.00 | 0.99 | 1.00 | 0.99 | 1.00 | 1.01 | 1.00 | 1.01 | 1.00 |
| Thiamine | ME891627 | 1.01 | 1.00 | 0.98 | 1.00 | 1.00 | 1.00 | 1.01 | 1.00 | 1.01 | 1.00 |
| Pyroglutamate | ME891531 | 1.01 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.01 | 0.99 | 1.01 | 1.00 |
| Creatinine | ME891517 | 1.00 | 1.00 | 0.98 | 1.00 | 1.00 | 1.00 | 1.01 | 0.99 | 1.01 | 1.00 |
| Pyridoxine | ME891569 | 1.01 | 1.00 | 0.98 | 1.00 | 1.00 | 1.00 | 1.01 | 0.99 | 1.01 | 1.00 |
| 3-Hydroxybutyric acid | ME891514 | 1.01 | 1.00 | 0.98 | 1.00 | 1.00 | 1.01 | 1.01 | 0.99 | 1.00 | 1.00 |
| Phosphorylcholine | ME891588 | 1.01 | 1.00 | 0.98 | 1.00 | 1.00 | 1.01 | 1.01 | 0.99 | 1.01 | 1.00 |
| Lactate | ME891509 | 1.01 | 1.00 | 0.98 | 1.00 | 0.99 | 1.01 | 1.01 | 0.98 | 1.01 | 1.00 |
| Urate | ME891566 | 1.01 | 1.00 | 0.98 | 1.00 | 0.99 | 1.01 | 1.01 | 0.99 | 1.01 | 1.00 |
| UDP-glucose | ME891665 | 1.01 | 0.99 | 1.00 | 1.01 | 1.01 | 0.99 | 1.00 | 0.99 | 1.01 | 1.00 |
| Oxalate | ME891508 | 1.02 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.01 | 0.99 | 0.99 |
| Palmitic acid | ME891625 | 1.01 | 0.99 | 1.00 | 1.01 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Dodecanoic acid | ME891605 | 1.02 | 0.99 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.99 | 1.00 |
| Myristic acid | ME891617 | 1.02 | 0.99 | 0.99 | 1.01 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Deoxyguanosine monophosphate | ME891648 | 1.02 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.99 | 0.99 | 1.01 | 1.00 |
| Glyceric acid | ME891513 | 1.01 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.99 | 0.99 | 1.00 | 1.01 |
| Creatine | ME891530 | 1.01 | 1.00 | 0.99 | 1.00 | 1.00 | 1.01 | 1.00 | 0.99 | 1.00 | 1.00 |
| Glutathione | ME891642 | 1.01 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 0.99 | 1.00 | 0.99 |
| Adenosine diphosphate | ME891653 | 1.01 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 0.99 | 0.99 | 1.00 | 1.00 |
| Pelargonic acid | ME891558 | 1.01 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 |
| Capric acid | ME891576 | 1.02 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| D5-Phenylalanine | ME891572 | 1.01 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Butyric acid | ME891505 | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| d4-tyrosine | ME891591 | 1.01 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Glutamate | ME891547 | 1.01 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| 3-Hydroxymethylglutarate | ME891563 | 1.01 | 1.00 | 1.00 | 1.00 | 1.01 | 0.99 | 1.00 | 0.99 | 1.00 | 1.00 |
| GDP-glucose | ME891668 | 1.01 | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 |
| Sorbitol | ME891587 | 1.01 | 1.00 | 1.00 | 0.99 | 0.99 | 1.00 | 1.00 | 1.00 | 1.01 | 1.00 |
| Cytidine diphosphate | ME891650 | 1.01 | 0.99 | 1.00 | 0.99 | 1.00 | 1.00 | 1.00 | 1.01 | 1.00 | 1.00 |
| Docosahexaenoic acid | ME891645 | 1.02 | 0.99 | 1.01 | 0.99 | 0.99 | 0.99 | 1.00 | 1.01 | 1.00 | 1.00 |
| N-acetylaspartate | ME891578 | 1.01 | 0.99 | 0.99 | 0.99 | 0.99 | 1.01 | 1.01 | 1.00 | 1.00 | 1.00 |
| Diacetyl | ME891504 | 1.01 | 0.99 | 1.00 | 1.00 | 0.99 | 1.01 | 0.99 | 1.00 | 1.00 | 1.00 |
| Oleic acid | ME891636 | 1.02 | 0.99 | 0.99 | 1.00 | 0.98 | 1.01 | 1.00 | 1.00 | 1.00 | 1.00 |
| Succinate | ME891524 | 1.02 | 0.99 | 0.99 | 0.99 | 1.00 | 1.02 | 1.00 | 0.99 | 1.00 | 1.01 |
| Adenosine monophosphate | ME891647 | 1.02 | 0.99 | 0.98 | 0.99 | 1.00 | 1.00 | 1.00 | 1.01 | 1.00 | 1.01 |
| D4-DL-Lysine | ME891546 | 1.03 | 0.99 | 0.99 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.01 | 1.00 |
| Sucrose | ME891678 | 1.02 | 0.99 | 0.99 | 0.99 | 1.00 | 1.00 | 1.00 | 0.99 | 1.01 | 1.00 |
| 10-Hydroxydecanoate | ME891595 | 1.03 | 0.99 | 0.99 | 1.02 | 1.02 | 1.00 | 1.00 | 0.98 | 0.99 | 0.98 |
| 12-Hydroxydodecanoic acid | ME891610 | 1.03 | 0.99 | 0.99 | 1.02 | 1.00 | 1.01 | 0.98 | 0.99 | 1.00 | 0.99 |
| 3-Sulfinoalanine | ME891551 | 1.01 | 1.01 | 0.99 | 1.01 | 1.01 | 0.97 | 0.99 | 0.98 | 1.01 | 1.02 |
| LPE(16:0/0:0) | ME891657 | 1.02 | 1.02 | 0.98 | 1.01 | 1.01 | 0.98 | 1.00 | 0.99 | 0.99 | 1.00 |
| LPE(18:1) | ME891659 | 1.03 | 1.01 | 0.97 | 1.01 | 1.00 | 0.99 | 1.01 | 0.99 | 1.00 | 1.00 |
| Pantothenic acid | ME891612 | 1.01 | 1.01 | 1.02 | 1.01 | 1.01 | 0.99 | 0.99 | 0.98 | 1.00 | 0.99 |
| Aspartic acid | ME891536 | 1.01 | 1.01 | 1.00 | 1.01 | 1.01 | 0.98 | 0.99 | 0.99 | 1.00 | 1.00 |
| Maleic acid | ME891520 | 1.02 | 1.01 | 1.01 | 1.01 | 1.01 | 0.98 | 0.98 | 0.98 | 1.00 | 1.00 |
| Oxidized glutathione | ME891670 | 1.02 | 1.01 | 1.00 | 1.01 | 1.01 | 0.99 | 1.00 | 0.98 | 0.99 | 0.98 |
| Pyruvate | ME891507 | 1.02 | 1.01 | 0.99 | 1.01 | 1.01 | 0.99 | 1.00 | 0.98 | 1.00 | 0.99 |
| Deaminoneuraminic acid | ME891628 | 1.03 | 1.00 | 1.00 | 1.00 | 1.00 | 0.99 | 0.99 | 0.98 | 1.01 | 0.99 |
| Uridine diphosphate | ME891651 | 1.02 | 1.00 | 1.00 | 1.00 | 1.01 | 1.00 | 1.00 | 0.98 | 1.01 | 0.99 |
Factors:
| F1 | ATF4:KO | Treatment_time:0 |
| F2 | ATF4:KO | Treatment_time:0.5 |
| F3 | ATF4:KO | Treatment_time:24 |
| F4 | ATF4:KO | Treatment_time:4 |
| F5 | ATF4:KO | Treatment_time:8 |
| F6 | ATF4:WT | Treatment_time:0 |
| F7 | ATF4:WT | Treatment_time:0.5 |
| F8 | ATF4:WT | Treatment_time:24 |
| F9 | ATF4:WT | Treatment_time:4 |
| F10 | ATF4:WT | Treatment_time:8 |
