Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003458)

(Analysis AN005681)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7
LLK_1	ME903638	0.63	1.38	0.91	NA	0.53	0.30	2.62
SLH	ME903652	0.47	1.34	0.78	NA	0.39	0.38	3.12
6-Aminocaproic acid	ME903618	3.46	0.95	0.47	NA	0.31	0.16	0.35
Phosphocholine	ME903557	3.06	0.70	0.68	NA	0.54	0.40	0.39
4-Amino-3-hydroxybenzoic acid_1	ME903615	2.70	2.59	0.14	NA	0.05	0.03	0.03
N-Acetylhistamine	ME903646	2.34	2.76	0.48	NA	0.01	0.01	0.01
N8-Acetylspermidine	ME903591	1.76	2.44	0.97	NA	0.11	0.28	0.25
N-Acetylhistidine	ME903553	1.67	1.96	1.08	NA	0.38	0.28	0.53
Methylimidazoleacetic acid	ME903641	2.58	1.62	1.17	NA	0.20	0.15	0.10
4-Amino-3-hydroxybenzoic acid_3	ME903617	2.10	1.34	0.73	NA	0.46	0.38	0.90
Acetohydroxamic acid	ME903621	2.62	1.41	0.81	NA	0.31	0.30	0.35
N1-Methyl-Adenosine	ME903550	2.29	1.33	0.81	NA	0.44	0.47	0.51
2,6-Dimethylpyrazine	ME903609	2.12	1.96	0.56	NA	0.33	0.32	0.46
6-Methylnicotinamide	ME903619	2.67	1.82	0.47	NA	0.28	0.19	0.25
VNK	ME903658	0.84	2.07	1.20	NA	0.29	0.20	1.60
FLK_1	ME903629	0.99	2.18	1.22	NA	0.29	0.13	1.31
LNK	ME903640	0.90	2.07	1.35	NA	0.25	0.30	1.30
TLK	ME903654	1.29	2.06	1.84	NA	0.32	0.22	0.31
VLK	ME903657	1.32	1.76	1.73	NA	0.48	0.27	0.50
FLK_2	ME903630	1.42	1.52	1.72	NA	0.58	0.40	0.39
Nα-({1,3,4-trihydroxy-5-[(N-methylvalyl)amino]cyclohexyl}carbonyl)phenylalaninamide	ME903647	1.53	1.57	1.75	NA	0.47	0.28	0.44
4-[2-(1H-indol-3-yl)ethyl]morpholine-3,5-dione	ME903614	1.43	1.82	1.71	NA	0.24	0.24	0.65
ALK_3	ME903626	1.27	1.89	1.49	NA	0.21	0.42	0.79
RLK	ME903651	1.23	2.03	2.36	NA	0.17	0.19	0.16
ALK_1	ME903624	1.39	1.79	2.28	NA	0.21	0.24	0.20
GLK	ME903631	1.32	1.85	2.32	NA	0.21	0.25	0.17
ALK_2	ME903625	1.44	2.35	2.09	NA	0.02	0.07	0.08
Nicotinic acid	ME903596	0.98	2.44	2.07	NA	0.18	0.19	0.21
3-Hydroxyhippuric acid	ME903526	0.46	0.37	1.05	NA	1.82	1.31	1.00
4-Guanidinobutyric acid	ME903529	0.68	0.58	1.31	NA	2.11	0.53	0.83
Nicotinamide N-oxide	ME903555	0.20	0.36	0.48	NA	2.00	1.01	2.10
N-Acetylornithine	ME903593	0.50	0.72	1.20	NA	1.43	0.66	1.72
Trigonelline	ME903606	0.21	0.60	1.18	NA	1.59	0.68	2.04
Indole-3-lactic acid	ME903585	1.63	0.89	0.12	NA	1.26	0.67	1.28
Trimethylamine N-Oxide	ME903607	1.55	0.86	0.24	NA	1.56	0.60	1.01
L-Ergothioneine	ME903635	1.55	0.58	0.73	NA	1.64	0.85	0.44
Anserine/ Homocarnosine	ME903571	0.89	0.69	0.44	NA	2.11	0.88	0.81
N-Acetylglutamine	ME903592	0.94	1.12	0.61	NA	1.69	0.56	0.98
N1-Methyl-2-pyridone-5-carboxamide	ME903590	1.68	1.21	0.75	NA	0.67	0.55	1.10
Thiamine	ME903603	1.27	1.16	0.83	NA	0.90	0.77	1.04
Glucosamine/ Galactosamine	ME903578	1.28	0.69	0.58	NA	1.25	0.91	1.26
Argininosuccinic acid	ME903572	1.32	0.77	0.91	NA	1.14	0.67	1.21
S-Adenosylmethionine	ME903602	1.49	0.65	0.93	NA	1.39	0.65	0.82
Allopurinol	ME903534	1.44	0.80	0.88	NA	1.10	0.82	0.91
Inosine	ME903547	1.53	0.77	0.88	NA	1.09	0.77	0.90
5-Hydroxylysine	ME903565	0.32	1.09	1.22	NA	1.38	0.85	1.27
3-Ureidopropionic acid	ME903528	0.49	0.89	0.65	NA	1.71	0.86	1.41
Acetylcarnitine	ME903531	0.51	0.84	0.84	NA	1.72	0.89	1.21
Adenine	ME903532	0.71	0.68	0.75	NA	1.42	0.96	1.55
Tiglylcarnitine	ME903605	0.69	0.79	0.81	NA	1.32	1.07	1.37
3-(3-pyridinyl)propanoic acid	ME903612	0.69	0.87	0.83	NA	1.36	1.01	1.25
Pyridoxamine	ME903600	0.68	0.86	0.90	NA	1.38	0.95	1.28
Butyrylcarnitine	ME903575	0.52	0.81	0.70	NA	1.32	1.22	1.46
Isovalerylcarnitine/ 2-Methylbutyroylcarnitine	ME903586	0.51	0.91	0.80	NA	1.33	1.07	1.44
Adenosine	ME903533	0.86	0.76	0.83	NA	1.49	0.83	1.24
Cystine	ME903541	0.84	0.85	1.00	NA	1.54	0.69	1.11
Glycerol 3-phosphate	ME903632	0.84	0.82	0.99	NA	1.48	0.76	1.14
Pipecolinic acid	ME903598	1.03	0.72	1.01	NA	1.27	0.80	1.23
N2-Acetyllysine	ME903551	0.87	0.80	0.90	NA	1.24	0.87	1.39
2-Amino-3-methoxybenzoic acid	ME903610	0.90	0.89	0.91	NA	1.18	0.96	1.18
Guanidoacetic acid	ME903543	0.85	0.77	0.96	NA	1.26	0.98	1.22
Riboflavin	ME903601	0.90	0.83	0.99	NA	1.28	0.85	1.21
Indole-3-carboxyaldehyde	ME903584	0.94	0.96	0.95	NA	0.99	0.83	1.43
Propionylcarnitine	ME903559	1.09	0.87	0.97	NA	1.02	0.85	1.25
N1-[3-(1H-Imidazol-1-yl)propyl]-2,6-dimethoxy-3-nitrobenzamide	ME903643	1.03	0.76	1.13	NA	1.04	1.14	0.90
Alanine	ME903570	0.91	0.98	1.17	NA	0.95	0.95	1.12
Betaine	ME903536	0.88	1.17	1.12	NA	0.87	0.91	1.12
Carnitine	ME903537	0.81	0.83	0.99	NA	1.11	1.12	1.19
γ-Aminobutyric acid	ME903608	0.98	0.95	1.00	NA	1.01	1.03	1.03
4-Hydroxyproline	ME903564	0.78	0.96	1.07	NA	1.11	1.04	1.08
Choline	ME903538	0.89	0.96	1.06	NA	1.04	0.99	1.10
Hypoxanthine	ME903546	0.85	0.90	1.02	NA	1.09	1.03	1.14
Nicotine amide	ME903595	0.94	0.90	0.99	NA	1.10	0.98	1.11
Guanosine monophosphate (GMP)	ME903544	1.15	1.03	1.25	NA	1.00	0.69	0.92
Nicotinamide riboside	ME903594	1.16	1.02	1.11	NA	0.94	0.77	1.02
Guanosine	ME903582	0.97	1.02	1.13	NA	1.06	0.97	0.84
N-acetylmannosamine	ME903554	1.03	1.05	1.04	NA	1.06	0.86	0.97
Glycine	ME903581	1.00	0.89	1.15	NA	1.08	0.87	1.06
3-amino-2-phenyl-2H-pyrazolo[4,3-c]pyridine-4,6-diol	ME903613	1.00	0.97	1.01	NA	1.20	0.79	1.04
Glutamic acid/ N-Methylaspartic acid	ME903579	1.04	0.94	1.07	NA	1.15	0.79	1.04
3-Aminoisobutanoic acid	ME903563	0.95	1.11	1.24	NA	0.64	1.10	1.03
3-Methylhistidine	ME903527	0.63	0.91	1.02	NA	0.90	1.32	1.30
Ecgonine	ME903628	0.82	0.97	1.06	NA	0.67	1.28	1.29
Purine	ME903599	0.75	0.99	1.23	NA	0.77	1.17	1.20
4-Amino-3-hydroxybenzoic acid_2	ME903616	2.21	1.07	1.37	NA	0.70	0.28	0.28
Histidine	ME903545	1.76	0.98	1.12	NA	0.69	0.68	0.74
Ketamine	ME903634	1.75	0.86	1.02	NA	0.78	0.78	0.74
Alanyltyrosine	ME903623	1.96	1.20	1.04	NA	0.62	0.52	0.56
Prolylleucine	ME903650	2.04	1.12	0.84	NA	0.77	0.52	0.55
PLK	ME903648	0.57	1.51	1.42	NA	0.91	0.87	0.76
5-Methyltryptophan	ME903567	1.29	0.77	1.30	NA	0.61	1.25	0.79
Acetyl-β-methylcholine	ME903622	1.37	0.92	1.81	NA	0.42	0.88	0.73
Homoarginine	ME903583	1.25	1.10	1.82	NA	0.37	0.93	0.66
Cytidine	ME903542	1.19	1.54	1.61	NA	0.65	0.40	0.68
Aspartame	ME903627	1.16	1.65	1.40	NA	0.79	0.34	0.67
N-(2-morpholinophenyl)-2-furamide	ME903642	1.21	1.51	1.38	NA	0.78	0.54	0.55
Leucylproline_1	ME903636	1.36	1.08	1.71	NA	0.65	0.70	0.58
Leucylproline_2	ME903637	1.55	1.10	1.87	NA	0.50	0.52	0.58
Carnosine	ME903576	1.50	1.06	1.43	NA	0.69	0.73	0.60
Glycylproline	ME903633	1.48	1.24	1.30	NA	0.69	0.69	0.56
7-Methylguanine	ME903530	1.41	1.17	1.55	NA	0.80	0.51	0.59
Acetylcarnosine	ME903569	1.50	1.30	1.43	NA	0.81	0.47	0.48
CMP	ME903539	1.23	1.26	1.47	NA	0.82	0.53	0.74
tert-Butyl N-[1-(aminocarbonyl)-3-methylbutyl]carbamate	ME903653	1.24	1.30	1.56	NA	0.65	0.59	0.75
Isoleucine	ME903548	1.22	1.22	1.51	NA	0.69	0.68	0.75
Lysine	ME903588	1.24	1.20	1.60	NA	0.68	0.64	0.72
Leucylalanine	ME903587	1.44	1.48	1.58	NA	0.48	0.43	0.65
N3,N4-Dimethyl-L-arginine	ME903644	1.37	1.35	1.69	NA	0.52	0.59	0.53
Tyrosylalanine_1	ME903655	1.43	1.36	1.73	NA	0.46	0.54	0.55
LLK_2	ME903639	1.38	1.37	1.58	NA	0.63	0.52	0.57
Tyrosylalanine_2	ME903656	1.39	1.25	1.65	NA	0.64	0.55	0.58
2-Picolinic acid	ME903525	0.82	1.34	1.66	NA	0.71	0.79	0.79
N6,N6,N6-Trimethyl-L-lysine	ME903645	1.02	1.16	1.68	NA	0.62	0.76	0.90
Acadesine	ME903568	1.21	1.33	1.29	NA	0.77	0.65	0.76
Deoxycytidine	ME903577	1.25	1.25	1.14	NA	0.79	0.62	0.98
Spermine	ME903560	1.18	1.09	1.21	NA	0.98	0.83	0.68
O-Acetylserine	ME903597	1.15	1.03	1.37	NA	0.74	0.85	0.94
Leucine	ME903549	1.17	1.14	1.40	NA	0.73	0.76	0.88
Methionine	ME903589	1.21	1.12	1.41	NA	0.72	0.75	0.84
Threonine/ Homoserine	ME903604	1.18	1.17	1.31	NA	0.74	0.73	0.93
Phenylalanine	ME903556	1.13	1.11	1.35	NA	0.74	0.79	0.95
Tryptophan	ME903561	1.14	1.13	1.40	NA	0.72	0.74	0.97
Proline	ME903558	1.13	1.11	1.29	NA	0.82	0.82	0.87
2-Amino-4-methylpyrimidine	ME903611	1.06	1.11	1.33	NA	0.81	0.84	0.91
Glutamine	ME903580	1.06	1.10	1.30	NA	0.86	0.81	0.95
5-Methoxytryptamine	ME903566	1.17	1.04	1.41	NA	0.84	0.74	0.88
AMP	ME903535	1.05	1.03	1.40	NA	0.92	0.79	0.88
N-Acetylalanine	ME903552	1.24	1.15	1.36	NA	0.80	0.75	0.72
7-Methylguanosine	ME903620	1.30	1.10	1.30	NA	0.83	0.67	0.84
Prolylglycine	ME903649	1.39	1.07	1.30	NA	0.78	0.70	0.77
Valine	ME903562	1.39	1.12	1.32	NA	0.74	0.65	0.81
Creatine	ME903540	1.25	1.06	1.17	NA	0.77	0.88	0.88
Asparagine	ME903573	1.34	0.98	1.22	NA	0.86	0.79	0.81
Aspartic acid	ME903574	1.35	0.98	1.21	NA	0.86	0.80	0.80

Factors:

F1	Sample source:Kidney \| Group:CLP (24h) / 12C-Serin
F2	Sample source:Kidney \| Group:CLP (24h) / 13C-Serin
F3	Sample source:Kidney \| Group:CLP (24h) / Vehicle
F4	Sample source:Kidney \| Group:QC
F5	Sample source:Kidney \| Group:Sham / 12C-Serin
F6	Sample source:Kidney \| Group:Sham / 13C-Serin
F7	Sample source:Kidney \| Group:Sham / Vehicle

Data matrix