Clustering data with hclust algorithm for (Study ST003459)
Reversed phase NEGATIVE ION MODE (Analysis AN005684)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 |
|---|---|---|---|---|---|---|---|---|
| Aspartic acid | ME903853 | 0.45 | 1.37 | 0.86 | NA | 0.83 | 1.46 | 0.99 |
| Hexoses | ME903861 | 0.23 | 0.56 | 0.61 | NA | 1.80 | 1.02 | 1.91 |
| Leucylalanine | ME903842 | 0.39 | 1.47 | 0.63 | NA | 1.28 | 1.22 | 0.88 |
| Pentoses | ME903871 | 0.34 | 0.85 | 0.81 | NA | 1.43 | 1.10 | 1.56 |
| Uridine | ME903879 | 0.68 | 1.33 | 1.20 | NA | 0.96 | 0.99 | 0.85 |
| Hexoses dimer | ME903862 | 0.04 | 0.09 | 0.07 | NA | 2.06 | 0.62 | 3.52 |
| Thymidine | ME903877 | 0.41 | 1.30 | 0.95 | NA | 0.28 | 2.13 | 0.90 |
| Mucic acid | ME903867 | 0.46 | 1.57 | 0.85 | NA | 0.92 | 1.29 | 0.84 |
| 4-pyridoxic acid | ME903836 | 0.67 | 1.42 | 0.81 | NA | 1.12 | 1.09 | 0.80 |
| Taurine | ME903875 | 0.80 | 1.29 | 1.35 | NA | 0.88 | 0.95 | 0.76 |
| N-Acetylalanine | ME903868 | 0.55 | 1.30 | 0.86 | NA | 0.95 | 1.35 | 0.95 |
| Galactonic acid/ Gluconic acid | ME903857 | 0.43 | 0.95 | 0.89 | NA | 1.19 | 1.24 | 1.37 |
| Gulonic acid γ-lactone | ME903860 | 0.43 | 0.94 | 0.91 | NA | 1.17 | 1.23 | 1.40 |
| N-Acetylglucosamine | ME903869 | 0.59 | 1.63 | 1.16 | NA | 0.80 | 1.00 | 0.81 |
| Threonic acid | ME903847 | 0.35 | 1.27 | 1.08 | NA | 1.36 | 0.86 | 1.13 |
| 2-C-Methyl-erythritol-4-phosphoric acid | ME903852 | 0.38 | 0.67 | 0.65 | NA | 1.69 | 1.10 | 1.57 |
| Serine | ME903873 | 0.67 | 1.00 | 0.83 | NA | 1.00 | 1.34 | 1.15 |
| N-Glycolylneuraminic acid | ME903883 | 0.40 | 1.68 | 1.16 | NA | 0.79 | 1.11 | 0.89 |
| Ribulose 5-phosphate | ME903872 | 0.59 | 0.96 | 0.78 | NA | 1.19 | 1.26 | 1.23 |
| Uracil | ME903848 | 1.07 | 1.45 | 1.15 | NA | 0.72 | 0.80 | 0.79 |
| cis-Aconitic acid | ME903854 | 0.93 | 0.61 | 1.03 | NA | 1.82 | 0.57 | 1.07 |
| 4-chloro-1H-indazol-3-amine | ME903882 | 0.82 | 1.32 | 1.35 | NA | 0.94 | 1.05 | 0.48 |
| N-Acetylneuraminic acid | ME903870 | 0.51 | 1.64 | 1.36 | NA | 0.52 | 1.06 | 0.98 |
| Lactic acid | ME903865 | 0.55 | 0.81 | 1.00 | NA | 1.47 | 0.74 | 1.59 |
| Xanthosine | ME903850 | 0.57 | 1.25 | 0.86 | NA | 1.25 | 1.00 | 1.06 |
| Oxidized glutathione | ME903844 | 0.50 | 1.31 | 1.14 | NA | 0.80 | 1.14 | 1.20 |
| Fumaric acid | ME903856 | 1.01 | 1.25 | 0.90 | NA | 0.83 | 1.11 | 0.84 |
| Hippuric acid | ME903841 | 0.72 | 1.65 | 0.85 | NA | 1.03 | 0.93 | 0.71 |
| Phenylalanine | ME903846 | 0.47 | 1.51 | 0.72 | NA | 0.97 | 1.33 | 0.90 |
| Uric acid | ME903878 | 0.96 | 1.77 | 1.21 | NA | 0.77 | 0.43 | 0.88 |
| Glucose-6-phosphate | ME903839 | 1.10 | 0.52 | 0.90 | NA | 1.36 | 1.14 | 0.94 |
| Glucuronic acid | ME903858 | 0.49 | 1.11 | 0.81 | NA | 1.02 | 1.37 | 1.20 |
| Allantoin | ME903838 | 0.79 | 1.19 | 1.13 | NA | 0.80 | 1.09 | 1.05 |
| Sugar alcohol (C5) | ME903874 | 0.41 | 1.12 | 1.05 | NA | 1.16 | 1.08 | 1.26 |
| Itaconic acid | ME903864 | 2.40 | 2.09 | 1.06 | NA | 0.05 | 0.10 | 0.09 |
| Threonine | ME903876 | 0.46 | 1.07 | 0.73 | NA | 1.09 | 1.39 | 1.25 |
| Malic acid | ME903843 | 0.97 | 1.46 | 0.81 | NA | 0.74 | 1.08 | 0.85 |
| Xanthine | ME903849 | 0.61 | 1.46 | 1.09 | NA | 0.76 | 1.14 | 0.93 |
| δ-Gluconolactone | ME903881 | 0.51 | 0.59 | 1.58 | NA | 0.78 | 0.93 | 2.01 |
| Isocitric acid | ME903863 | 0.91 | 0.68 | 0.98 | NA | 1.67 | 0.59 | 1.22 |
| Pantothenic acid | ME903845 | 0.43 | 1.42 | 0.59 | NA | 1.03 | 1.50 | 0.91 |
| 2-Aminoadipic acid | ME903851 | 0.16 | 2.65 | 1.12 | NA | 0.10 | 1.50 | 0.33 |
| Methanesulfonic acid | ME903866 | 0.24 | 1.54 | 0.49 | NA | 0.59 | 2.15 | 0.80 |
| Adenosine diphosphate ribose | ME903837 | 0.75 | 1.17 | 0.93 | NA | 1.41 | 0.93 | 0.73 |
| α-aminobutyric acid/ N,N-Dimethylglycine | ME903880 | 0.39 | 1.21 | 0.86 | NA | 1.10 | 1.31 | 1.12 |
| Glutamic acid/ N-Methylaspartic acid | ME903859 | 0.37 | 1.19 | 0.84 | NA | 1.18 | 1.29 | 1.11 |
| Glycylleucine | ME903840 | 0.33 | 1.51 | 0.65 | NA | 1.13 | 1.39 | 0.86 |
| Deoxyuridine | ME903855 | 0.21 | 2.12 | 0.95 | NA | 0.22 | 1.81 | 0.56 |
Factors:
| F1 | Sample source:Liver | Group:CLP (24h) / 12C-Serin |
| F2 | Sample source:Liver | Group:CLP (24h) / 13C-Serin |
| F3 | Sample source:Liver | Group:CLP (24h) / Vehicle |
| F4 | Sample source:Liver | Group:QC |
| F5 | Sample source:Liver | Group:Sham / 12C-Serin |
| F6 | Sample source:Liver | Group:Sham / 13C-Serin |
| F7 | Sample source:Liver | Group:Sham / Vehicle |
