Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003460)

(Analysis AN005685)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7
N-Acetylglucosamine	ME903951	1.66	1.79	1.49	NA	0.44	0.34	0.37
Nicotinic acid	ME903961	1.56	2.56	1.96	NA	0.05	0.08	0.03
Urocanic acid	ME903910	1.32	2.81	1.82	NA	0.06	0.11	0.06
N-Acetylglutamic acid	ME903900	1.54	2.20	0.42	NA	0.36	0.57	0.48
4-Amino-3-hydroxybenzoic acid_2	ME903978	2.13	2.76	0.49	NA	0.06	0.03	0.04
1-Methyladenine	ME903975	2.47	2.08	1.25	NA	0.03	0.03	0.03
N-Acetylneuraminic acid	ME903901	2.47	2.14	1.13	NA	0.05	0.02	0.00
Butorphanol	ME903983	3.81	1.01	0.85	NA	0.00	0.00	0.00
N-Acetylhistidine	ME903954	2.83	1.41	0.45	NA	0.33	0.23	0.30
N-Acetylhistamine	ME903994	2.63	1.60	0.87	NA	0.21	0.27	0.14
δ-Valerolactam	ME903999	2.60	1.57	0.67	NA	0.17	0.40	0.23
N-Acetyltyrosine	ME903959	3.02	0.97	0.52	NA	0.31	0.40	0.40
O-Acetylserine	ME903963	3.12	0.68	0.38	NA	0.46	0.44	0.49
N-AcetylProline	ME903957	2.42	0.93	0.32	NA	0.73	0.70	0.41
4-Amino-3-hydroxybenzoic acid_1	ME903977	2.44	1.27	0.47	NA	0.49	0.42	0.52
N1-Methyl-2-pyridone-5-carboxamide	ME903948	2.63	1.11	0.46	NA	0.50	0.41	0.49
3-Hydroxy-2-methyl-4-pyrone	ME903915	2.46	0.46	1.49	NA	0.52	0.71	0.49
Desoxycortone	ME903988	2.24	1.18	1.46	NA	0.10	0.58	0.57
N-Acetylglycine	ME903953	2.45	0.87	0.84	NA	0.19	0.90	0.56
3^-Adenosine monophosphate (3^-AMP)	ME903885	0.00	0.14	0.03	NA	3.12	0.51	1.95
Xanthosine	ME903974	0.09	0.80	0.59	NA	2.13	0.61	1.77
Hippuric acid	ME903936	0.30	0.30	0.07	NA	2.75	0.88	1.30
N-Acetylphenylalanine	ME903956	0.16	0.18	0.07	NA	2.30	1.44	1.53
Nicotinamide N-oxide	ME903960	0.46	0.31	0.18	NA	2.17	0.91	1.76
Indole-3-methyl acetate	ME903941	0.27	0.29	0.08	NA	1.55	1.40	2.26
Guanosine	ME903935	0.04	0.31	0.20	NA	1.60	0.60	3.46
Adenosine	ME903924	0.04	0.30	0.14	NA	2.02	0.60	2.95
Allopurinol	ME903926	0.00	0.47	0.43	NA	2.18	0.41	2.63
Inosine	ME903896	0.02	0.48	0.43	NA	2.30	0.40	2.45
4,8-Dihydroxyquinoline-2-carboxylic acid	ME903919	2.20	0.82	0.36	NA	1.65	0.24	0.21
Trimethylamine N-Oxide	ME903971	1.40	0.40	0.12	NA	2.50	0.42	0.64
Daidzein	ME903931	0.17	1.55	1.09	NA	1.82	0.51	0.88
Clomazone_1	ME903984	2.04	0.43	0.48	NA	0.74	0.90	1.20
Clomazone_2	ME903985	1.94	0.57	0.53	NA	0.78	0.92	1.04
Homocarnosine	ME903937	1.31	1.20	0.68	NA	0.87	1.09	0.59
Glutamic acid	ME903893	1.11	1.25	0.61	NA	0.90	1.09	0.79
Indole-3-acetic acid	ME903939	1.20	1.33	0.67	NA	0.84	0.90	0.86
5,6-Dihydrothymine	ME903922	1.29	1.45	0.85	NA	0.52	1.04	0.70
Indole-3-lactic acid	ME903940	1.38	1.24	1.10	NA	0.59	0.89	0.80
Creatine	ME903929	1.27	1.14	0.89	NA	0.73	0.99	0.89
2-Amino-4-methylpyrimidine	ME903976	1.36	1.11	0.85	NA	0.73	0.91	0.96
Histidine	ME903894	1.34	1.11	0.88	NA	0.74	0.90	0.97
N6,N6,N6-Trimethyl-L-lysine	ME903993	1.57	1.12	1.17	NA	0.93	0.64	0.54
5-Hydroxyindole-3-acetic acid	ME903923	1.39	1.16	0.90	NA	0.99	0.78	0.65
N8-Acetylspermidine	ME903949	1.28	1.11	0.97	NA	1.24	0.74	0.53
4-pyridoxic acid	ME903921	1.28	1.01	0.53	NA	1.28	0.78	0.85
N2-Acetyllysine	ME903898	1.42	1.04	0.49	NA	1.35	0.59	0.81
Creatinine	ME903930	1.56	1.01	0.65	NA	1.04	0.79	0.71
N-Isovalerylglycine	ME903962	1.36	0.93	0.54	NA	0.98	0.97	1.00
Norketamine	ME903996	1.43	0.84	0.84	NA	0.95	0.88	0.96
Prolylleucine	ME903997	1.81	0.81	0.65	NA	1.31	0.58	0.55
N-Acetylglutamine	ME903952	2.05	1.43	0.71	NA	0.69	0.40	0.44
Taurine	ME903906	1.79	0.94	0.80	NA	0.67	0.83	0.82
Phosphocholine	ME903965	2.07	1.13	0.96	NA	0.71	0.44	0.57
7-Methylguanine	ME903887	1.88	1.09	0.63	NA	1.00	0.56	0.54
Acipimox	ME903982	1.94	1.04	0.74	NA	0.82	0.61	0.63
Allantoin	ME903889	2.00	1.06	0.67	NA	0.75	0.66	0.60
3-Hydroxyhippuric acid	ME903916	1.02	0.48	0.44	NA	1.64	0.78	1.48
Galactosamine	ME903933	0.81	0.54	0.15	NA	1.66	1.04	1.49
Trigonelline	ME903908	0.63	1.08	0.85	NA	1.53	0.64	1.27
Carnitine	ME903928	0.59	1.09	0.58	NA	1.60	0.92	1.00
DL-Carnitine	ME903989	0.60	1.10	0.58	NA	1.60	0.92	0.98
Kynurenic acid/ Indole-3-glyoxylic acid	ME903943	0.98	0.99	0.44	NA	1.67	0.69	0.93
N-Acetylarginine	ME903899	0.99	1.07	0.43	NA	1.49	0.77	0.95
4-Guanidinobutyric acid	ME903920	0.64	0.95	0.84	NA	2.03	0.48	0.96
Thiamine	ME903970	0.45	0.89	0.69	NA	1.98	0.82	1.03
1-Methyladenosine	ME903884	0.47	0.78	0.30	NA	2.07	0.93	1.14
5-Aminolevulinic acid	ME903886	0.44	0.72	0.55	NA	2.05	0.87	1.21
2-Aminoadipic acid	ME903912	0.65	1.86	1.25	NA	0.47	1.17	0.64
2-Picolinic acid	ME903914	0.73	1.43	1.01	NA	0.98	0.67	1.25
Indole-3-carboxyaldehyde	ME903895	0.68	1.53	0.73	NA	0.91	0.99	1.03
3-Ureidopropionic acid	ME903918	0.66	1.75	0.89	NA	0.69	0.96	1.00
N-Methylhydantoin	ME903995	0.66	1.70	0.93	NA	0.69	0.97	1.03
Pantothenic acid	ME903903	0.72	1.70	1.22	NA	0.73	0.83	0.87
Choline	ME903891	0.71	1.43	1.00	NA	0.76	1.10	1.00
Pyroglutamic acid	ME903905	0.82	1.41	1.27	NA	0.68	1.06	0.85
Deoxycytidine	ME903932	1.00	0.56	0.34	NA	1.03	1.54	1.26
Octanoylcarnitine	ME903964	0.74	0.54	0.31	NA	0.99	1.76	1.42
Isoleucine	ME903942	0.49	1.29	0.72	NA	0.96	1.11	1.39
Leucine	ME903945	0.59	1.35	0.80	NA	0.89	1.05	1.30
Valine	ME903911	0.62	1.27	0.76	NA	0.93	1.11	1.25
Threonine	ME903907	0.67	1.04	0.68	NA	0.98	1.23	1.32
Tyrosine	ME903972	0.54	1.20	0.67	NA	1.08	1.19	1.21
4-Indolecarbaldehyde	ME903979	0.44	1.16	0.60	NA	1.13	1.26	1.28
Tryptophan	ME903909	0.40	1.18	0.58	NA	1.11	1.31	1.28
Alanine	ME903925	0.41	1.04	0.70	NA	1.22	1.24	1.33
Proline	ME903966	0.47	1.05	0.81	NA	1.08	1.32	1.23
Betaine	ME903890	0.70	1.00	0.72	NA	1.15	0.94	1.47
N-Acetylornithine	ME903955	0.50	0.85	0.62	NA	1.29	1.12	1.57
Homocitrulline	ME903938	0.40	0.90	0.72	NA	1.23	1.21	1.53
Nicotine amide	ME903902	0.42	1.02	0.72	NA	1.26	1.10	1.46
Methionine sulfoxide	ME903897	0.53	0.80	0.72	NA	1.27	1.26	1.38
Methionine	ME903947	0.41	0.93	0.59	NA	1.16	1.39	1.42
N-Acetyltryptophan	ME903958	0.57	0.89	0.56	NA	1.14	1.31	1.41
2-Methylbutyroylcarnitine	ME903913	0.36	1.03	0.46	NA	1.03	1.63	1.30
Propionylcarnitine	ME903967	0.44	1.07	0.38	NA	1.36	1.31	1.17
Butyrylcarnitine	ME903927	0.60	0.74	0.38	NA	1.33	1.44	1.27
Cytidine	ME903892	0.57	0.72	0.53	NA	1.28	1.45	1.29
Acetyl-L-carnitine	ME903888	1.26	0.64	0.54	NA	1.03	1.19	1.14
Serine	ME903968	1.07	0.75	0.52	NA	1.19	1.11	1.15
3-Methylhistidine	ME903917	0.99	0.95	0.63	NA	0.88	1.45	0.89
Vanillyl alcohol	ME903973	1.08	1.19	0.42	NA	0.87	1.23	0.89
Glycine	ME903934	0.95	1.01	0.86	NA	1.04	1.14	0.90
Pipecolinic acid	ME903904	0.84	0.99	0.65	NA	1.17	1.03	1.19
Acetyl-β-methylcholine	ME903981	0.90	0.92	0.80	NA	1.11	1.07	1.14
6-Methoxyquinoline	ME903980	0.80	0.92	0.79	NA	1.12	1.09	1.23
Serotonin	ME903969	0.88	0.89	0.72	NA	1.10	1.08	1.24
Lysine	ME903946	0.74	1.11	0.86	NA	1.11	1.06	1.08
N3,N4-Dimethyl-L-arginine	ME903992	0.71	1.05	0.79	NA	1.30	1.05	0.99
Corticosterone	ME903986	1.06	1.22	0.97	NA	0.52	1.08	1.17
Esketamine	ME903991	0.92	1.02	0.84	NA	0.88	1.09	1.22
Deschloroketamine	ME903987	1.08	0.95	0.79	NA	0.77	1.07	1.32
Xylazine	ME903998	0.98	1.00	0.84	NA	0.81	1.06	1.32
N-Acetylalanine	ME903950	1.00	1.25	0.76	NA	0.78	1.04	1.06
Ecgonine	ME903990	0.95	1.07	0.70	NA	0.76	1.25	1.16
Kynurenine	ME903944	0.83	1.19	0.71	NA	0.76	1.24	1.16

Factors:

F1	Sample source:Serum \| Group:CLP (24h) / 12C-Serin
F2	Sample source:Serum \| Group:CLP (24h) / 13C-Serin
F3	Sample source:Serum \| Group:CLP (24h) / Vehicle
F4	Sample source:Serum \| Group:QC
F5	Sample source:Serum \| Group:Sham / 12C-Serin
F6	Sample source:Serum \| Group:Sham / 13C-Serin
F7	Sample source:Serum \| Group:Sham / Vehicle

Data matrix