Clustering data with hclust algorithm for (Study ST003468)
Reversed phase NEGATIVE ION MODE (Analysis AN005702)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 |
|---|---|---|---|---|---|---|---|---|
| PG 18:1/22:4 | ME905682 | 2.24 | 1.50 | 1.32 | NA | 0.41 | 0.18 | 0.24 |
| (+/-)11(12)-EET | ME905717 | 0.47 | 1.61 | 1.77 | NA | 0.43 | 1.33 | 0.43 |
| PG 18:1/20:3 | ME905680 | 0.80 | 0.93 | 0.68 | NA | 1.02 | 1.24 | 1.33 |
| PG 22:4/22:4 | ME905693 | 0.55 | 0.83 | 0.71 | NA | 1.06 | 1.32 | 1.61 |
| CL 68:4 | ME905711 | 0.84 | 1.26 | 0.89 | NA | 1.54 | 0.52 | 0.91 |
| PI 16:0/22:4 | ME905697 | 0.85 | 1.05 | 1.24 | NA | 1.09 | 0.78 | 1.07 |
| PI 18:0/20:3 | ME905699 | 0.97 | 1.11 | 1.18 | NA | 1.08 | 0.72 | 0.99 |
| CL 16:0/18:1/18:1/18:2 | ME905640 | 0.89 | 1.22 | 1.11 | NA | 1.23 | 0.64 | 0.91 |
| CL 16:0/18:2/18:1/18:2 | ME905641 | 0.89 | 1.15 | 0.99 | NA | 1.18 | 0.80 | 0.96 |
| CL 16:1/18:2/16:1/18:2 | ME905642 | 0.99 | 0.92 | 0.84 | NA | 1.34 | 0.84 | 1.03 |
| CL 16:1/18:2/18:2/18:2 | ME905644 | 0.89 | 0.93 | 0.83 | NA | 1.36 | 0.83 | 1.16 |
| PE O-16:1/16:0 | ME905666 | 0.89 | 0.98 | 0.92 | NA | 1.28 | 0.80 | 1.15 |
| CL 16:1/18:2/18:1/18:2 | ME905643 | 0.84 | 1.06 | 0.85 | NA | 1.29 | 0.87 | 1.06 |
| CL 18:2/18:2/18:2/20:3 | ME905653 | 0.84 | 1.00 | 0.87 | NA | 1.32 | 0.87 | 1.09 |
| CL 16:1/18:2/18:2/20:4 | ME905645 | 0.92 | 1.03 | 0.92 | NA | 1.23 | 0.84 | 1.06 |
| CL 68:5 | ME905712 | 0.95 | 1.01 | 0.88 | NA | 1.29 | 0.86 | 0.98 |
| PE O-16:1/24:4 | ME905668 | 0.97 | 1.03 | 0.88 | NA | 1.04 | 0.86 | 1.26 |
| CL 18:2/18:2/18:2/20:4 | ME905654 | 0.88 | 1.07 | 0.92 | NA | 1.14 | 0.87 | 1.13 |
| PG 22:4/22:5 | ME905694 | 0.92 | 1.11 | 0.85 | NA | 1.06 | 0.89 | 1.18 |
| CL 18:2/18:2/18:2/18:2 | ME905652 | 0.73 | 1.05 | 0.89 | NA | 1.15 | 0.90 | 1.34 |
| CL 18:1/18:2/18:1/18:2 | ME905648 | 0.74 | 1.26 | 0.99 | NA | 1.13 | 0.81 | 1.10 |
| CL 18:2/18:2/18:2/22:6 | ME905655 | 0.80 | 1.11 | 0.99 | NA | 1.08 | 0.93 | 1.12 |
| CL 18:1/18:2/18:2/18:2 | ME905650 | 0.76 | 1.13 | 0.92 | NA | 1.16 | 0.85 | 1.21 |
| CL 18:1/20:3/18:2/18:2 | ME905651 | 0.68 | 1.15 | 1.01 | NA | 1.16 | 0.89 | 1.16 |
| PE O-15:1/22:6 | ME905665 | 1.17 | 0.99 | 0.85 | NA | 0.99 | 0.86 | 1.14 |
| PG 18:1/18:2 | ME905679 | 1.12 | 0.84 | 0.90 | NA | 0.90 | 1.03 | 1.24 |
| PG 20:4/22:4 | ME905691 | 0.93 | 1.11 | 0.80 | NA | 0.82 | 1.15 | 1.17 |
| PG 20:3/20:4 | ME905690 | 1.23 | 1.11 | 0.69 | NA | 0.78 | 1.09 | 1.04 |
| PG 18:1/20:4 | ME905681 | 1.17 | 0.98 | 0.87 | NA | 0.80 | 1.10 | 1.07 |
| PG 18:2/20:4 | ME905686 | 1.18 | 1.07 | 0.95 | NA | 0.66 | 1.10 | 1.03 |
| PG 16:0/20:2 | ME905677 | 0.98 | 1.29 | 1.14 | NA | 0.80 | 0.74 | 1.12 |
| PG 34:1 | ME905714 | 0.99 | 1.23 | 1.19 | NA | 0.80 | 0.68 | 1.20 |
| PI 18:0/20:4 | ME905700 | 0.88 | 1.16 | 1.27 | NA | 0.85 | 0.86 | 1.08 |
| PI 18:0/22:4 | ME905701 | 0.80 | 1.29 | 1.28 | NA | 0.87 | 0.80 | 1.04 |
| SL 17:0;O/16:0 | ME905719 | 1.10 | 1.18 | 0.88 | NA | 0.89 | 1.04 | 0.84 |
| SL 17:0;O/17:0;O | ME905720 | 1.07 | 1.15 | 0.90 | NA | 0.89 | 1.02 | 0.92 |
| PG 18:1/18:1 | ME905678 | 1.16 | 1.14 | 1.01 | NA | 0.79 | 0.87 | 1.03 |
| PE 17:0/20:4 | ME905659 | 1.13 | 1.11 | 1.04 | NA | 0.91 | 0.88 | 0.94 |
| PG 18:2/22:5 | ME905688 | 1.13 | 1.06 | 1.04 | NA | 0.89 | 0.92 | 0.97 |
| PG 18:2/22:4 | ME905687 | 0.93 | 0.99 | 0.97 | NA | 0.90 | 1.04 | 1.21 |
| Cer 18:1;2O/20:0_2 | ME905635 | 0.79 | 1.09 | 1.01 | NA | 0.92 | 1.01 | 1.26 |
| PE O-18:1/18:1 | ME905671 | 0.81 | 1.05 | 1.04 | NA | 0.81 | 1.09 | 1.29 |
| Cer 18:1;2O/22:0_2 | ME905636 | 0.87 | 1.16 | 1.01 | NA | 0.96 | 0.97 | 1.04 |
| PI 34:1 | ME905716 | 0.84 | 1.25 | 1.04 | NA | 0.87 | 0.99 | 1.02 |
| PG 18:1/22:6 | ME905684 | 0.94 | 1.26 | 1.10 | NA | 0.82 | 0.92 | 0.97 |
| Cer 18:1;2O/24:1_2 | ME905638 | 0.93 | 1.18 | 1.05 | NA | 0.90 | 0.94 | 1.02 |
| Cer 18:1;2O/24:2 | ME905639 | 0.98 | 1.17 | 1.07 | NA | 0.88 | 0.90 | 1.02 |
| PE 20:3/20:3 | ME905664 | 1.00 | 1.15 | 1.05 | NA | 0.89 | 0.88 | 1.06 |
| PE 18:0/20:1 | ME905661 | 0.87 | 1.20 | 1.04 | NA | 0.82 | 0.96 | 1.18 |
| PE O-17:1/20:4 | ME905669 | 0.94 | 1.16 | 0.94 | NA | 0.80 | 1.04 | 1.13 |
| PE O-17:1/22:6 | ME905670 | 0.95 | 1.15 | 0.99 | NA | 0.83 | 1.00 | 1.09 |
| PE O-18:1/22:6 | ME905674 | 0.92 | 1.12 | 1.01 | NA | 0.87 | 0.99 | 1.13 |
| PS 18:0/18:1 | ME905706 | 0.97 | 1.03 | 1.08 | NA | 0.95 | 0.87 | 1.18 |
| PE 19:1/19:2 | ME905662 | 0.99 | 1.07 | 0.92 | NA | 0.94 | 0.92 | 1.18 |
| PE O-18:1/22:5 | ME905673 | 0.99 | 1.09 | 0.97 | NA | 0.88 | 0.94 | 1.16 |
| PE O-18:2/22:4 | ME905675 | 1.03 | 1.13 | 0.98 | NA | 0.87 | 0.90 | 1.12 |
| ST 27:1;O;S | ME905721 | 0.95 | 1.03 | 1.33 | NA | 0.82 | 1.04 | 0.88 |
| PE O-18:1/20:1 | ME905672 | 0.62 | 1.17 | 1.17 | NA | 0.67 | 1.18 | 1.31 |
| PE O-20:1/18:2 | ME905676 | 0.75 | 1.21 | 1.16 | NA | 0.70 | 1.07 | 1.20 |
| PI O-18:0_20:4 | ME905718 | 0.81 | 1.24 | 1.22 | NA | 0.76 | 0.99 | 1.05 |
| Cer 18:1;2O/22:1 | ME905637 | 1.06 | 1.71 | 0.86 | NA | 0.93 | 0.70 | 0.62 |
| PG 20:4/22:6 | ME905692 | 1.08 | 1.49 | 1.11 | NA | 0.54 | 0.98 | 0.76 |
| PG 22:5/22:6 | ME905695 | 0.82 | 1.44 | 1.14 | NA | 0.66 | 1.10 | 0.83 |
| CL 18:1/18:2/18:1/20:3 | ME905649 | 0.60 | 1.39 | 1.14 | NA | 0.92 | 0.90 | 1.12 |
| CL 18:1/18:1/18:1/18:2 | ME905646 | 0.80 | 1.47 | 1.25 | NA | 0.92 | 0.72 | 0.87 |
| PS 20:4/20:4 | ME905709 | 0.74 | 1.53 | 1.07 | NA | 0.88 | 0.86 | 0.92 |
| PS 20:4/22:6 | ME905710 | 0.71 | 1.52 | 1.21 | NA | 0.82 | 0.81 | 0.98 |
| CL 18:1/18:1/18:1/20:3 | ME905647 | 0.60 | 1.67 | 1.35 | NA | 0.75 | 0.81 | 0.88 |
| PS 20:3/20:4 | ME905708 | 0.80 | 1.61 | 1.24 | NA | 0.72 | 0.83 | 0.81 |
| PG 22:6/22:6 | ME905696 | 0.94 | 1.74 | 1.50 | NA | 0.52 | 0.67 | 0.67 |
| FA 22:6 | ME905713 | 1.32 | 1.54 | 1.23 | NA | 0.41 | 0.73 | 0.75 |
| PS 18:0/20:5 | ME905707 | 1.10 | 1.36 | 1.22 | NA | 0.72 | 0.80 | 0.82 |
| LPE 16:0 | ME905656 | 1.18 | 1.30 | 1.32 | NA | 0.69 | 0.68 | 0.89 |
| LPE 18:0 | ME905657 | 1.02 | 1.34 | 1.38 | NA | 0.62 | 0.82 | 0.89 |
| PG 18:2/18:2 | ME905685 | 1.11 | 1.34 | 1.36 | NA | 0.67 | 0.76 | 0.80 |
| PG 18:2/22:6 | ME905689 | 1.06 | 1.37 | 1.36 | NA | 0.69 | 0.72 | 0.86 |
| PI 16:0/22:6 | ME905698 | 0.94 | 1.32 | 1.54 | NA | 0.84 | 0.64 | 0.82 |
| PS 16:0/16:0 | ME905704 | 1.17 | 1.24 | 1.65 | NA | 0.83 | 0.53 | 0.65 |
| PG 34:3 | ME905715 | 1.34 | 0.63 | 0.71 | NA | 1.19 | 0.90 | 1.21 |
| PE 16:0/16:0 | ME905658 | 1.46 | 1.01 | 0.82 | NA | 1.10 | 0.68 | 0.86 |
| PE 17:1/17:2 | ME905660 | 1.72 | 0.86 | 0.78 | NA | 1.08 | 0.58 | 0.90 |
| PE 20:2/22:6 | ME905663 | 1.68 | 1.00 | 0.82 | NA | 1.05 | 0.67 | 0.67 |
| PE O-16:1/20:5 | ME905667 | 1.34 | 0.98 | 1.08 | NA | 0.90 | 0.76 | 0.95 |
| PG 18:1/22:5 | ME905683 | 1.33 | 1.05 | 0.93 | NA | 0.91 | 0.81 | 0.92 |
| PI 18:1/18:2 | ME905702 | 1.54 | 1.04 | 1.27 | NA | 0.75 | 0.57 | 0.86 |
| PI 18:2/20:4 | ME905703 | 1.24 | 1.17 | 1.34 | NA | 0.73 | 0.56 | 1.06 |
| PS 16:0/18:1 | ME905705 | 1.26 | 1.01 | 1.38 | NA | 0.87 | 0.67 | 0.87 |
Factors:
| F1 | Sample source:Spleen | Group:CLP (24h) / 12C-Serin |
| F2 | Sample source:Spleen | Group:CLP (24h) / 13C-Serin |
| F3 | Sample source:Spleen | Group:CLP (24h) / Vehicle |
| F4 | Sample source:Spleen | Group:QC |
| F5 | Sample source:Spleen | Group:Sham / 12C-Serin |
| F6 | Sample source:Spleen | Group:Sham / 13C-Serin |
| F7 | Sample source:Spleen | Group:Sham / Vehicle |
