Clustering data with hclust algorithm for (Study ST003485)
(Analysis AN005723)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 |
|---|---|---|---|---|---|---|---|---|
| Picolinic acid | ME908442 | 5.38 | 0.66 | 0.30 | 0.14 | 0.21 | 0.17 | 0.14 |
| Anthranilate | ME908441 | 1.57 | 0.42 | 4.24 | 0.15 | 0.14 | 0.27 | 0.20 |
| Indoxyl | ME908438 | 1.80 | 2.09 | 2.77 | 0.08 | 0.10 | 0.07 | 0.08 |
| 5-hydroxytryptophan | ME908443 | 1.97 | 0.81 | 1.25 | 0.67 | 0.92 | 0.64 | 0.76 |
| Indole-3-acetate | ME908437 | 2.72 | 0.60 | 1.18 | 1.22 | 0.41 | 0.41 | 0.46 |
| 5-Hydroxyindoleacetate | ME908432 | 1.01 | 0.88 | 1.37 | 0.67 | 0.76 | 0.79 | 1.52 |
| kynurenine | ME908439 | 1.05 | 0.92 | 1.44 | 0.64 | 0.75 | 0.69 | 1.51 |
| N-formyl kynurenine | ME908440 | 1.36 | 1.14 | 1.86 | 0.71 | 0.46 | 0.58 | 0.90 |
| 3-Methyldioxyindole | ME908433 | 1.48 | 1.40 | 2.53 | 0.39 | 0.26 | 0.45 | 0.48 |
| Indole-3-acetaldehyde | ME908436 | 1.22 | 1.05 | 2.37 | 0.61 | 0.70 | 0.50 | 0.54 |
| L-tryptophan | ME908444 | 1.07 | 1.12 | 2.42 | 0.61 | 0.71 | 0.51 | 0.56 |
| 3-Methyleneoxindole | ME908434 | 1.12 | 1.09 | 2.37 | 0.62 | 0.71 | 0.52 | 0.57 |
| Indole | ME908435 | 1.11 | 1.09 | 2.34 | 0.61 | 0.74 | 0.53 | 0.58 |
Factors:
| F1 | cell line:BT549 | TDO2 status:sh negative control | Treatment:none | Sample source:culture media |
| F2 | cell line:BT549 | TDO2 status:shTDO2-82 | Treatment:none | Sample source:culture media |
| F3 | cell line:BT549 | TDO2 status:shTDO2-98 | Treatment:none | Sample source:culture media |
| F4 | cell line:SUM159PT | TDO2 status:empty vector | Treatment:vehicle | Sample source:culture media |
| F5 | cell line:SUM159PT | TDO2 status:overexpression | Treatment:10 uM AT0174 | Sample source:culture media |
| F6 | cell line:SUM159PT | TDO2 status:overexpression | Treatment:1 uM AT0174 | Sample source:culture media |
| F7 | cell line:SUM159PT | TDO2 status:overexpression | Treatment:vehicle | Sample source:culture media |
