Clustering data with hclust algorithm for (Study ST003501)
(Analysis AN005746)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 |
|---|---|---|---|---|---|---|---|
| Coenzyme Q10 | ME910563 | 1.01 | 0.88 | 1.01 | 1.06 | 0.85 | 1.08 |
| PC(16:0/5:0(CHO)) | ME910617 | 0.99 | 0.94 | 1.00 | 1.01 | 0.93 | 1.10 |
| DG(18:0_22:6) | ME910569 | 1.04 | 0.93 | 1.09 | 1.03 | 1.01 | 0.94 |
| Cer(d18:1/18:0) | ME910557 | 1.03 | 1.08 | 1.03 | 1.03 | 0.94 | 0.97 |
| LacCer(d18:1/18:0) | ME910589 | 1.06 | 1.05 | 1.06 | 1.03 | 0.93 | 0.94 |
| LacCer(d18:1/16:0) | ME910587 | 0.92 | 0.97 | 0.98 | 1.02 | 1.05 | 1.01 |
| HexCer(d18:1/24:0) | ME910584 | 0.98 | 0.95 | 0.98 | 1.13 | 0.99 | 1.00 |
| HexCer(d18:1/24:1) | ME910585 | 0.97 | 0.98 | 0.97 | 1.14 | 1.02 | 0.96 |
| PE(36:2) | ME910638 | 1.04 | 0.99 | 1.00 | 1.05 | 1.02 | 0.95 |
| HexCer(d18:1/18:0) | ME910582 | 1.00 | 1.00 | 1.00 | 1.09 | 0.98 | 0.97 |
| Sitosteryl hexoside | ME910647 | 0.99 | 1.01 | 1.02 | 1.10 | 0.99 | 0.96 |
| PC(16:0/9:0(CHO)) | ME910618 | 0.96 | 1.00 | 1.01 | 1.01 | 0.96 | 1.06 |
| CE(18:1) | ME910546 | 0.94 | 1.04 | 1.00 | 0.96 | 1.00 | 1.03 |
| CE(18:1(d7)) | ME910545 | 0.97 | 1.02 | 0.99 | 0.97 | 1.00 | 1.02 |
| TG(15:0/18:1(d7)/15:0) | ME910660 | 0.96 | 1.02 | 0.99 | 0.98 | 1.00 | 1.02 |
| MG(18:1) | ME910611 | 1.09 | 0.98 | 0.99 | 1.00 | 0.97 | 0.99 |
| PE(36:4) | ME910639 | 1.07 | 0.96 | 1.04 | 1.02 | 0.94 | 1.00 |
| DG(16:0_20:4) | ME910566 | 1.08 | 0.94 | 1.03 | 1.02 | 0.96 | 1.00 |
| DG(18:1_20:4) | ME910571 | 1.08 | 0.95 | 1.04 | 1.02 | 0.95 | 1.01 |
| PE(34:1) | ME910636 | 1.06 | 0.98 | 1.03 | 1.04 | 0.97 | 0.97 |
| Cer(d18:1/16:0) | ME910556 | 1.05 | 0.96 | 1.02 | 1.04 | 0.97 | 0.99 |
| PE(38:6) | ME910642 | 1.05 | 0.98 | 1.03 | 1.02 | 0.96 | 0.99 |
| PE(40:7) | ME910646 | 1.05 | 0.97 | 1.03 | 1.02 | 0.96 | 0.99 |
| PC(36:2) | ME910624 | 1.04 | 0.97 | 1.02 | 1.02 | 0.98 | 1.00 |
| PE(38:5) | ME910641 | 1.05 | 0.96 | 1.02 | 1.02 | 0.97 | 1.01 |
| DG(16:0_18:1) | ME910565 | 1.03 | 0.94 | 1.01 | 1.02 | 0.98 | 1.02 |
| Cer(d18:1/24:0) | ME910558 | 1.03 | 0.95 | 1.02 | 1.04 | 0.94 | 1.04 |
| Cer(d18:1/24:1) | ME910559 | 1.05 | 0.95 | 1.03 | 1.04 | 0.95 | 1.02 |
| HexCer(d18:1/16:0) | ME910581 | 1.04 | 0.98 | 1.02 | 1.00 | 1.00 | 0.98 |
| LPC(26:0) | ME910602 | 0.99 | 0.99 | 1.01 | 0.98 | 1.01 | 1.00 |
| PE(40:4) | ME910643 | 1.00 | 0.99 | 1.01 | 1.02 | 1.00 | 0.99 |
| PC(O-16:0/0:0) | ME910630 | 1.01 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Sphingosine(d17:1) | ME910659 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| SM(d18:1(d9)/18:1) | ME910648 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| PE(15:0/18:1(d7)) | ME910633 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| PC(15:0/18:1(d7)) | ME910616 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| LPC(18:1(d7)) | ME910596 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| LPC(18:1) | ME910597 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| LacCer(d18:1/17:0) | ME910588 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Glucosylsphingosine(d5) | ME910580 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| GlcCer(d18:1(d5)/18:0) | ME910577 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| GlcCer(d18:1/16:0(d3)) | ME910579 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| GB3(d18:1/18:0(d3)) | ME910573 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Cer(d18:1/16:0(d7)) | ME910555 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Cholesterol(d7) | ME910561 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| DG(15:0/18:1(d7)) | ME910564 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| lyso-GB3-d7 | ME910605 | 0.99 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| LPC(18:0) | ME910595 | 1.00 | 1.00 | 0.99 | 1.01 | 1.00 | 1.00 |
| Cholesterol | ME910560 | 1.00 | 0.99 | 0.99 | 1.01 | 1.01 | 1.00 |
| LPC(16:0) | ME910593 | 1.00 | 0.99 | 1.00 | 1.01 | 1.00 | 1.00 |
| MG(18:1(d7)) | ME910610 | 1.00 | 1.00 | 1.00 | 1.01 | 1.00 | 0.99 |
| SM(d18:1/16:0) | ME910649 | 1.00 | 1.00 | 0.99 | 1.01 | 1.01 | 0.99 |
| PC(O-18:0/2:0) | ME910632 | 1.01 | 0.99 | 0.98 | 1.03 | 1.00 | 1.00 |
| PC(36:1) | ME910623 | 0.99 | 0.99 | 0.99 | 1.03 | 1.00 | 1.01 |
| TG(18:1_34:2) | ME910662 | 0.99 | 0.99 | 0.99 | 1.01 | 1.00 | 1.01 |
| SM(d18:1/24:0) | ME910651 | 1.00 | 0.97 | 1.00 | 1.03 | 0.97 | 1.03 |
| DG(18:1/18:1) | ME910570 | 1.01 | 0.96 | 0.99 | 1.01 | 1.00 | 1.02 |
| DG(18:0_20:4) | ME910568 | 1.00 | 0.97 | 1.01 | 1.01 | 0.99 | 1.02 |
| SM(d18:1/24:1) | ME910652 | 1.00 | 0.97 | 1.00 | 1.02 | 0.99 | 1.01 |
| PC(16:0/9:0(COOH)) | ME910619 | 0.99 | 0.99 | 1.03 | 1.01 | 0.99 | 1.01 |
| TG(18:0_36:2) | ME910661 | 1.00 | 0.98 | 1.03 | 1.00 | 0.99 | 1.01 |
| SM(d18:1/18:0) | ME910650 | 1.00 | 0.99 | 1.01 | 1.03 | 0.98 | 1.01 |
| PC(40:6) | ME910629 | 1.00 | 0.99 | 1.02 | 1.01 | 0.96 | 1.02 |
| PE(40:6) | ME910645 | 1.00 | 0.99 | 1.02 | 1.01 | 0.97 | 1.02 |
| PE(38:4) | ME910640 | 1.02 | 0.98 | 1.02 | 1.01 | 0.97 | 1.02 |
| PC(34:1) | ME910622 | 1.03 | 0.98 | 1.02 | 1.01 | 0.97 | 1.01 |
| PC(38:6) | ME910627 | 1.03 | 0.98 | 1.02 | 1.01 | 0.96 | 1.01 |
| PC(40:5) | ME910628 | 1.01 | 0.97 | 1.02 | 1.01 | 0.97 | 1.03 |
| PC(36:4) | ME910625 | 1.03 | 0.97 | 1.02 | 1.01 | 0.96 | 1.02 |
| PC(38:4) | ME910626 | 1.02 | 0.97 | 1.02 | 1.01 | 0.96 | 1.03 |
| LPC(22:6) | ME910599 | 1.04 | 1.00 | 1.01 | 1.01 | 0.97 | 1.00 |
| LPC(16:1) | ME910594 | 1.02 | 0.98 | 1.01 | 1.01 | 0.99 | 1.00 |
| LPC(20:4) | ME910598 | 1.02 | 0.99 | 1.01 | 1.00 | 0.98 | 1.01 |
| PE(36:1) | ME910637 | 0.99 | 0.98 | 0.99 | 1.05 | 1.01 | 1.00 |
| DG(18:0_18:1) | ME910567 | 1.01 | 0.94 | 0.99 | 1.05 | 0.98 | 1.03 |
| HexCer(d18:1/22:0) | ME910583 | 1.00 | 0.95 | 1.00 | 1.08 | 0.98 | 1.01 |
Factors:
| F1 | genotype:APP | condition:high | group:high_disease | Sample source:microglia |
| F2 | genotype:APP | condition:low | group:low_disease | Sample source:microglia |
| F3 | genotype:APP | condition:mid | group:mid_disease | Sample source:microglia |
| F4 | genotype:NA | condition:NA | group:NA | Sample source:microglia |
| F5 | genotype:WT | condition:low | group:low_healthy | Sample source:microglia |
| F6 | genotype:WT | condition:mid | group:mid_healthy | Sample source:microglia |
