Clustering data with hclust algorithm for (Study ST003516)
Reversed phase NEGATIVE ION MODE (Analysis AN005773)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|---|
| 6-Phosphogluconic_acid_(area_norm) | ME915755 | 2.13 | 0.07 | NA | NA | 0.06 | NA | NA | 0.02 |
| Itaconic_acid | ME915749 | 0.98 | 0.08 | NA | 1.46 | 0.73 | 0.86 | 2.48 | 0.40 |
| Xylulose/Ribose/Ribulose_5-phosphate | ME915744 | 1.66 | 0.30 | NA | 1.13 | 1.65 | 0.62 | 0.87 | 0.76 |
| Erytrose-4-phosphate_(area_norm) | ME915756 | 2.19 | 0.22 | NA | 0.80 | 1.35 | 0.97 | 0.99 | 0.49 |
| Sedoheptulose_7-phosphate | ME915745 | 1.86 | 0.33 | NA | 0.86 | 1.20 | 1.03 | 1.03 | 0.69 |
| Glucose_6-phosphate | ME915742 | 2.63 | 0.23 | NA | 0.50 | 1.90 | 0.41 | 0.61 | 0.72 |
| Ribose/Ribulose_5-phosphate | ME915743 | 2.82 | 0.08 | NA | 0.53 | 1.11 | 0.55 | 0.69 | 1.21 |
| NADH | ME915752 | 1.35 | 1.49 | NA | 0.57 | 0.60 | 1.49 | 0.96 | 0.53 |
| Adenosine_5-triphosphate | ME915736 | 0.87 | 2.09 | NA | 0.21 | 1.15 | 0.27 | 0.45 | 1.97 |
| "D-Fructose_1,6-biphosphate_(area_norm)" | ME915754 | 1.33 | 2.04 | NA | 0.37 | 0.66 | 0.44 | 0.61 | 1.55 |
| L-Malic_acid | ME915750 | 0.88 | 1.81 | NA | 0.82 | 0.73 | 0.59 | 0.94 | 1.23 |
| Pyruvic_acid | ME915738 | 0.66 | 2.34 | NA | 0.54 | 0.58 | 0.77 | 0.71 | 1.40 |
| alpha-Ketoglutaric_acid | ME915739 | 0.63 | 1.35 | NA | 0.57 | 0.86 | 0.58 | 0.93 | 2.09 |
| Lactic_acid | ME915737 | 1.07 | 1.15 | NA | 0.87 | 0.56 | 0.66 | 0.85 | 1.85 |
| Fructose_6-phosphate | ME915741 | 1.40 | 0.69 | NA | 0.52 | 1.51 | 0.51 | 0.68 | 1.69 |
| DL-Glyceraldehyde_3-phosphate_(area_norm) | ME915753 | 1.09 | 0.68 | NA | 0.80 | 1.02 | 0.94 | 1.09 | 1.38 |
| NAD | ME915740 | 1.13 | 0.59 | NA | 0.78 | 1.09 | 0.88 | 1.11 | 1.42 |
| Adenosine_5-diphosphate | ME915735 | 1.00 | 0.88 | NA | 0.60 | 1.02 | 0.65 | 1.03 | 1.81 |
| NADP | ME915747 | 0.72 | 0.77 | NA | 0.86 | 0.98 | 0.82 | 1.13 | 1.73 |
| Succinic_acid | ME915748 | 0.86 | 0.53 | NA | 1.12 | 1.04 | 0.68 | 1.55 | 1.23 |
| Citric_acid | ME915751 | 1.44 | 0.30 | NA | 0.70 | 1.40 | 0.70 | 1.26 | 1.19 |
| Glutathione_Reduced | ME915746 | 1.21 | 0.30 | NA | 0.96 | 1.24 | 0.91 | 1.25 | 1.12 |
Factors:
| F1 | Sample source:J774A.1_murine_macrophages | Experimental_Group:6-aminonicotinamide | Treatment:6-aminonicotinamide_11µM_for_24hrs | Genotype:wildtype |
| F2 | Sample source:J774A.1_murine_macrophages | Experimental_Group:6-phosphogluconate_dehydrogenase_knockdown | Treatment:- | Genotype:sh6PGD2 |
| F3 | Sample source:J774A.1_murine_macrophages | Experimental_Group:Calibration_Curve | Treatment:- | Genotype:ISTD+SAMPLE_MIX |
| F4 | Sample source:J774A.1_murine_macrophages | Experimental_Group:Control | Treatment:- | Genotype:wildtype |
| F5 | Sample source:J774A.1_murine_macrophages | Experimental_Group:empty_vector_control | Treatment:- | Genotype:MLP |
| F6 | Sample source:J774A.1_murine_macrophages | Experimental_Group:Oxythiamine | Treatment:Oxythiamine_520µM_for_24hrs | Genotype:wildtype |
| F7 | Sample source:J774A.1_murine_macrophages | Experimental_Group:Physcion | Treatment:Physcion_9µM_for_24hrs | Genotype:wildtype |
| F8 | Sample source:J774A.1_murine_macrophages | Experimental_Group:Transketolase_knockdown | Treatment:- | Genotype:shTKT2 |
