Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003604)

Reversed phase POSITIVE ION MODE (Analysis AN005922)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10
Xanthine 13C5	ME934750	0.08	0.04	2.09	0.09	0.53	1.07	4.11	0.89	0.62	1.22
Asparagine 13C5	ME934739	0.05	0.07	1.72	0.65	0.13	0.17	2.85	3.40	0.39	1.27
5-Oxoproline 13C5	ME934751	0.09	0.06	2.40	0.48	0.13	0.17	3.13	2.54	0.47	1.48
Glutamate 13C5	ME934741	0.01	0.01	2.59	0.46	0.12	0.17	3.20	2.67	0.41	1.36
Cadaverine 13C5	ME934754	NA	0.06	1.25	0.51	0.07	0.03	2.54	2.30	0.17	0.18
Putrescine 13C4	ME934755	NA	NA	1.55	0.39	0.99	0.72	1.86	1.39	0.45	0.64
Proline 13C5	ME934746	NA	0.02	1.22	0.15	0.42	0.51	2.57	1.29	0.89	2.18
Serine 13C3	ME934747	NA	NA	1.17	0.27	NA	0.36	1.87	1.71	0.29	0.85
Alanine 13C3	ME934737	0.03	NA	1.13	0.24	0.27	0.26	2.26	1.87	0.70	1.52
Citrulline 13C6	ME934753	0.02	0.03	1.17	0.26	0.23	0.23	2.64	1.81	0.87	1.32
Hypoxanthine 13C5	ME934749	0.01	0.01	1.07	0.06	3.33	3.76	0.71	0.33	0.77	0.96
Tetradecenoyl Carnitine (acyl-C14:1)	ME934732	4.55	0.64	0.14	0.15	1.18	0.27	0.43	0.36	1.97	0.45
acyl-C18:2 (Linoleoyl-CoA)	ME934736	3.09	0.99	0.08	0.18	0.18	0.14	0.67	0.32	1.90	0.95
NAD+	ME934672	3.01	1.43	0.21	0.13	0.24	0.15	1.02	0.61	1.64	1.13
butanoyl-l-carnitine (acyl-C4)	ME934727	3.25	0.92	0.55	0.40	1.49	0.81	0.39	0.65	1.22	0.52
O-dodecanoyl-carnitine (acyl-C12)	ME934730	3.78	0.85	0.46	0.35	0.79	0.65	0.45	0.49	1.58	0.74
O-tetradecanoyl-L-carnitine (acyl-C14)	ME934731	3.24	1.00	0.37	0.16	1.23	0.74	0.53	0.45	1.63	0.65
Hexadecenoyl-carnitine (acyl-C16:1)	ME934734	3.11	0.83	0.33	0.38	0.96	0.46	0.72	0.61	1.89	0.88
O-octadecenoyl-L-carnitine (acyl-C18:1)	ME934735	2.94	1.02	0.33	0.28	1.10	0.51	0.82	0.51	1.68	0.79
Spermine	ME934695	1.05	2.64	0.45	0.19	0.65	0.45	0.62	0.37	0.88	1.07
S-Adenosyl-L-methionine	ME934687	0.85	0.58	0.98	0.26	3.18	1.83	0.56	0.54	0.95	0.69
Dopamine	ME934723	1.22	0.62	0.55	0.33	2.79	1.44	0.37	0.29	2.03	0.53
Indolepyruvate	ME934715	1.45	0.60	0.81	0.10	2.51	1.59	0.64	0.34	1.74	0.62
L-leucine	ME934646	1.70	0.58	0.77	0.10	2.93	1.73	0.39	0.18	1.44	0.59
L-tyrosine	ME934654	1.61	0.49	0.73	0.10	3.22	2.18	0.37	0.19	1.19	0.45
L-methionine	ME934648	1.36	0.66	0.45	0.05	3.24	2.46	0.27	0.11	1.30	0.44
L-phenylalanine	ME934649	1.51	0.63	0.46	0.07	3.18	2.42	0.25	0.13	1.14	0.58
L-cysteine	ME934642	1.17	0.57	0.54	0.06	2.64	2.66	0.37	0.19	1.23	1.01
Guanine	ME934661	1.29	0.71	0.41	0.28	2.94	2.00	0.73	0.30	1.26	0.37
Indole	ME934712	1.32	0.71	0.57	0.34	2.56	2.25	0.45	0.32	1.10	0.68
L-lysine	ME934647	1.51	0.74	0.67	0.10	2.42	2.17	0.45	0.25	1.21	0.74
L-tryptophan	ME934653	1.45	0.65	0.74	0.11	2.67	2.01	0.51	0.29	1.24	0.69
Cytidine	ME934663	0.72	1.29	0.38	0.03	2.86	3.47	0.17	0.09	0.42	0.29
GMP	ME934660	1.07	0.70	1.33	0.07	2.72	2.37	0.60	0.33	0.77	0.35
Nicotinamide	ME934671	0.96	0.68	1.07	0.05	2.59	2.82	0.45	0.15	1.02	0.52
g-Oxalo-crotonate	ME934720	0.38	0.81	1.11	0.07	3.07	2.49	0.67	0.22	0.73	0.63
Hypoxanthine	ME934665	0.46	0.74	1.16	0.06	3.39	2.81	0.43	0.17	0.62	0.42
Inosine	ME934664	0.54	0.94	0.71	0.03	3.54	2.81	0.25	0.14	0.72	0.40
Glutathione disulfide	ME934674	0.56	1.18	1.65	0.47	1.37	1.28	1.34	1.36	0.28	0.32
Histidine 13C6	ME934742	1.42	0.70	1.04	0.14	0.89	0.55	1.80	1.32	1.40	0.80
acyl-C4-OH (Hydroxybutyrylcarnitine)	ME934728	0.70	1.30	1.20	0.14	0.76	0.55	1.58	0.80	1.02	1.64
L-aspartate	ME934641	1.16	1.09	1.03	0.77	1.08	0.54	1.38	1.28	0.72	0.85
Phosphoserine	ME934686	1.00	1.42	1.03	0.83	0.44	0.54	1.47	1.01	1.07	0.89
5-Oxoproline	ME934675	1.26	1.17	1.11	0.38	0.74	0.97	1.23	0.87	0.99	1.13
L-glutamate	ME934643	1.15	1.17	1.19	0.41	0.59	0.72	1.39	0.97	1.06	1.18
Anthranilate	ME934718	0.70	0.84	0.93	0.27	1.84	1.68	0.90	0.39	1.01	1.60
Argininosuccinate	ME934691	0.90	0.79	1.36	0.22	1.24	1.66	0.92	0.51	0.95	1.66
acetyl-carnitine (acyl-C2)	ME934726	0.93	1.08	0.83	0.09	2.15	1.43	0.76	0.55	1.06	1.02
3-Methyldioxyindole	ME934711	1.31	0.72	0.82	0.51	2.10	1.77	0.60	0.47	1.18	0.79
5-Aminopentanoate	ME934705	1.38	0.60	1.14	0.31	2.38	1.64	0.69	0.46	1.15	0.66
L-valine	ME934655	1.38	0.60	1.14	0.31	2.38	1.64	0.69	0.46	1.15	0.66
Pyridoxal	ME934670	1.07	0.89	0.91	0.33	1.45	1.88	0.80	0.53	1.01	1.24
L-asparagine	ME934640	1.31	0.84	0.85	0.21	1.86	2.09	0.71	0.41	0.86	1.01
Cysteine 13C3	ME934740	1.24	0.89	1.02	0.19	1.65	1.83	0.88	0.49	0.89	1.00
Picolinic acid	ME934719	1.22	0.88	1.03	0.18	1.71	1.80	0.89	0.48	0.90	1.01
L-histidine	ME934645	1.14	0.89	1.06	0.31	1.75	1.77	1.00	0.77	0.81	0.62
L-serine	ME934651	1.21	0.76	0.88	0.40	2.02	2.25	0.76	0.69	0.66	0.61
L-Homoserine	ME934688	1.21	0.82	0.94	0.22	2.08	2.00	0.86	0.55	0.86	0.65
L-threonine	ME934652	1.21	0.82	0.94	0.22	2.08	2.00	0.86	0.55	0.86	0.65
L-Methionine S-oxide	ME934709	1.63	0.63	1.73	0.19	1.83	1.18	0.82	0.47	1.02	0.86
Creatinine	ME934700	0.98	0.79	1.42	0.37	1.84	1.34	0.87	0.77	1.02	0.80
L-alanine	ME934638	0.90	0.85	1.65	0.32	1.66	1.45	1.06	0.58	0.89	0.79
L-proline	ME934650	0.93	0.86	1.66	0.22	1.67	1.66	1.06	0.44	0.80	0.84
Adenosine	ME934658	1.33	1.63	0.43	0.10	1.50	1.07	0.34	0.29	1.92	0.76
Spermidine	ME934694	1.33	1.39	0.58	0.11	1.35	1.57	0.41	0.32	1.26	1.30
Acetylcholine	ME934725	2.19	1.37	0.52	0.15	0.79	0.51	0.89	0.66	1.39	1.16
Guanidinoacetate	ME934704	2.09	1.13	0.77	0.05	1.23	0.94	1.02	0.21	1.49	0.94
L-Palmitoylcarnitine (acyl-C16)	ME934733	2.18	1.18	0.61	0.32	1.25	0.86	0.80	0.66	1.15	0.81
5-Hydroxyindoleacetate	ME934710	0.73	1.15	1.00	0.26	1.71	0.82	0.87	0.71	1.47	1.17
Adenine	ME934659	1.25	1.06	0.97	0.36	1.49	0.93	0.81	0.71	1.40	0.98
L-Homocysteine	ME934683	1.46	0.66	0.33	NA	1.90	0.87	0.74	0.17	1.37	1.06
L-arginine	ME934639	1.79	0.93	0.45	0.16	2.14	1.27	0.44	0.55	1.23	1.11
AMP	ME934656	2.07	0.97	0.71	0.12	1.87	1.07	0.60	0.58	1.26	0.77
acyl-C5-OH (hydroxyisovalerylcarnitine)	ME934729	1.90	1.02	0.94	0.21	1.44	1.18	0.64	0.39	1.38	0.88
Cys-Gly	ME934677	1.78	0.91	0.80	0.14	1.79	1.25	0.57	0.47	1.45	0.94
2-Aminomuconate	ME934721	1.49	1.41	0.53	0.22	1.74	1.07	0.60	0.59	0.78	0.87
Indole-3-acetate	ME934714	1.55	1.36	0.51	0.31	1.75	0.97	0.69	0.72	0.85	0.92
CMP	ME934662	1.39	1.39	1.02	0.08	1.43	1.36	0.81	0.47	0.75	0.89
Glutathione	ME934673	1.55	1.01	1.06	0.18	1.56	1.36	0.75	0.60	1.10	0.81
5-Hydroxyisourate	ME934667	1.95	1.12	1.11	0.06	1.56	1.45	0.68	0.43	0.84	0.70
L-glutamine	ME934644	1.65	1.04	0.98	0.24	1.50	1.73	0.62	0.46	0.85	0.88
L-Adrenaline	ME934722	1.67	1.18	1.04	0.19	1.19	1.06	1.07	0.66	1.16	0.60
4-Acetamidobutanoate	ME934701	1.45	1.04	0.85	0.68	1.07	1.17	0.86	0.77	1.09	0.97
Hypotaurine	ME934708	1.44	1.06	1.17	0.45	1.20	1.29	0.91	0.79	0.90	0.73
Pantetheine	ME934706	1.22	0.97	0.17	NA	1.37	0.53	NA	NA	1.45	0.55
gamma-L-Glutamylputrescine	ME934681	1.98	0.96	0.01	0.01	1.47	0.76	0.02	0.04	2.11	0.94
Cystathionine	ME934684	1.94	0.74	0.33	0.09	1.41	0.96	0.09	0.10	2.54	1.39
N-formyl kynurenine	ME934717	2.19	0.82	0.14	0.04	1.54	1.22	0.14	0.12	2.55	1.42
Pantetheine 4--phosphate	ME934707	1.68	0.86	0.28	0.05	1.65	1.10	0.36	0.26	1.98	1.43
(5-L-Glutamyl)-L-glutamine	ME934682	1.96	0.78	0.74	0.21	1.70	1.15	0.47	0.35	1.76	1.12
gamma-L-Glutamyl-D-alanine	ME934679	1.92	0.74	0.46	0.13	1.90	1.41	0.29	0.24	2.02	1.16
Carnosine	ME934696	1.75	0.71	0.12	NA	2.12	1.44	0.21	0.13	1.54	0.87
gamma-Glutamyl-gamma-aminobutyrate	ME934680	2.40	0.62	0.07	0.01	2.14	1.26	0.12	0.06	2.02	1.19
N-Acetyl-L-citrulline	ME934702	1.98	1.09	0.03	0.04	2.10	1.32	0.04	0.07	2.25	0.99
N-Acetylornithine	ME934703	2.07	0.82	0.32	0.08	2.32	1.14	0.13	0.08	2.22	0.98
Dimethylglycine	ME934685	0.33	0.38	0.51	0.12	1.90	1.26	0.32	0.28	2.35	3.18
kynurenine	ME934716	1.13	0.95	0.87	0.47	0.94	1.15	0.36	0.51	2.74	0.95
2^,3^-Cyclic CMP	ME934668	0.53	0.59	0.82	0.34	1.25	1.44	0.45	0.75	2.09	1.31
dAMP	ME934657	0.42	0.39	0.81	0.10	1.44	1.29	0.90	0.74	2.44	2.07
Tryptophan 13C11	ME934748	0.69	0.68	0.77	0.80	0.84	0.77	1.06	0.79	1.61	2.31
Arginine 13C6	ME934738	NA	NA	0.30	0.20	0.32	0.29	1.49	0.80	1.04	2.07
Lysine 13C6	ME934744	NA	NA	0.74	0.09	0.56	0.62	1.48	0.62	1.15	1.99
Leucine/isoleucine 13C6	ME934743	NA	NA	0.85	0.05	0.69	0.44	1.22	0.39	2.14	2.21
Methionine 13C5	ME934745	0.11	0.07	0.76	0.06	1.33	0.96	1.52	0.44	1.67	1.71
5-Guanidino-2-oxopentanoate	ME934697	0.06	0.08	4.93	0.44	0.52	0.24	2.03	1.90	0.45	0.28
Cadaverine	ME934692	0.02	0.02	3.30	0.94	0.89	0.78	1.31	1.03	0.34	0.38
Phosphocreatine	ME934698	0.95	0.50	4.28	0.30	1.19	1.12	0.18	0.24	1.41	0.33
S-Glutathionyl-L-cysteine	ME934676	0.69	1.02	3.59	0.40	1.16	1.02	0.79	0.48	0.38	0.45
Indole-3-acetaldehyde	ME934713	1.13	0.45	3.21	0.13	1.70	1.53	0.61	0.27	1.03	0.50
gamma-Glutamyl-Se-methylselenocysteine	ME934678	0.26	0.40	3.23	0.75	1.62	1.99	0.87	0.38	0.40	0.69
L-Citrulline	ME934690	0.64	0.40	4.00	0.24	1.39	1.55	0.82	0.46	0.60	0.48
Serotonin	ME934724	0.63	0.38	4.12	0.25	1.38	1.63	0.75	0.53	0.56	0.40
Creatine	ME934699	0.71	0.45	3.44	0.42	2.06	1.56	0.44	0.47	0.63	0.35
Allantoate	ME934666	0.36	0.44	3.74	0.62	1.77	1.27	0.81	0.40	0.45	0.70
Ornithine	ME934689	0.37	0.41	3.67	0.45	1.89	1.66	0.75	0.35	0.44	0.59
S-Adenosyl-L-methionine 13C15	ME934752	0.67	0.22	2.35	0.04	2.78	2.70	0.44	0.21	0.55	0.35
5-6-Dihydrothymine	ME934669	0.77	0.56	2.44	0.51	2.39	1.23	0.65	0.53	0.86	0.49
Putrescine	ME934693	0.47	0.33	1.71	0.30	2.08	1.34	1.23	1.01	1.30	0.90

Factors:

F1	time (h):0 \| Dead E coli treatment:no \| inhibitor:none \| \| genotype:RagA GTP mutant
F2	time (h):0 \| Dead E coli treatment:no \| inhibitor:none \| \| genotype:WT
F3	time (h):18 \| Dead E coli treatment:yes \| inhibitor:150 nM concanamycin A \| \| genotype:WT
F4	time (h):18 \| Dead E coli treatment:yes \| inhibitor:50 nM bafilomycin A1 \| \| genotype:WT
F5	time (h):18 \| Dead E coli treatment:yes \| inhibitor:none \| \| genotype:RagA GTP mutant
F6	time (h):18 \| Dead E coli treatment:yes \| inhibitor:none \| \| genotype:WT
F7	time (h):6 \| Dead E coli treatment:yes \| inhibitor:150 nM concanamycin A \| \| genotype:WT
F8	time (h):6 \| Dead E coli treatment:yes \| inhibitor:50 nM bafilomycin A1 \| \| genotype:WT
F9	time (h):6 \| Dead E coli treatment:yes \| inhibitor:none \| \| genotype:RagA GTP mutant
F10	time (h):6 \| Dead E coli treatment:yes \| inhibitor:none \| \| genotype:WT

Data matrix