Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003830)

(Analysis AN006291)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9
DEOXYADENOSINE	ME1013197	1.19	0.90	0.51	0.78	0.74	1.98	0.91	0.66	2.41
N.acetylmethionine	ME1013163	1.20	1.36	1.14	0.31	0.45	0.98	0.74	0.39	1.33
TRIGONELLINE	ME1013179	0.47	0.70	0.57	1.49	1.32	1.67	1.30	1.49	1.71
dCytidine	ME1013142	0.33	0.59	0.51	1.56	1.72	1.65	1.70	1.49	1.59
DEOXYCYTIDINE	ME1013199	0.35	0.59	0.61	1.57	1.56	1.56	1.54	1.55	1.60
DEOXYURIDINE	ME1013090	0.45	0.79	1.17	1.82	2.13	0.79	0.54	1.58	0.05
formyl_methionine	ME1013143	0.96	1.07	1.28	1.39	0.99	0.59	0.72	0.96	0.35
thymidine	ME1013226	0.98	0.84	1.24	1.67	1.14	0.73	0.80	1.25	0.18
Glycerophosphocholine.2	ME1013203	0.87	0.77	1.26	1.42	1.51	0.93	0.93	0.93	0.38
amidoadipate	ME1013102	0.65	0.84	0.98	1.89	1.67	0.82	0.85	1.33	0.49
GALACTOSAMINE	ME1013200	0.78	0.86	0.95	1.67	1.57	0.94	0.91	1.25	0.55
N.METHYLGLUTAMATE	ME1013215	0.75	0.87	1.06	1.61	1.52	0.79	0.93	1.18	0.54
ADENOSINE.DIPHOSPHATE.RIBOSE	ME1013137	1.21	0.82	0.62	0.50	1.12	1.82	1.51	0.94	1.46
palmitate	ME1013167	0.67	0.83	1.36	0.41	1.05	1.06	0.83	1.10	1.51
D.MANNOSAMINE	ME1013089	1.25	0.72	0.72	1.28	1.09	1.10	1.63	1.14	1.07
amidoadipate.1	ME1013190	0.94	0.83	0.96	1.35	1.23	1.13	0.76	1.36	0.88
Riboflavin	ME1013097	0.98	0.92	0.74	1.00	1.00	1.18	1.45	0.92	1.50
2.hydroxyglutarate	ME1013131	0.99	0.93	0.74	0.94	0.90	1.31	1.27	0.96	1.59
IMP	ME1013154	0.94	0.92	0.69	1.00	0.84	1.27	1.45	0.97	1.71
glutamate.1	ME1013202	0.96	0.86	0.81	1.15	0.87	1.41	1.19	0.91	1.53
INDOXYL.SULFATE	ME1013156	0.97	0.96	0.85	0.92	0.98	1.17	1.23	0.95	1.38
O.SUCCINYL.HOMOSERINE	ME1013216	0.96	0.87	0.85	1.03	0.99	1.32	1.05	1.07	1.43
3.METHYLHISTAMINE	ME1013186	0.87	0.83	0.85	1.26	0.75	1.20	1.38	1.29	1.29
3.DEHYDROSHIKIMATE	ME1013133	0.81	0.83	1.06	1.20	1.25	0.80	1.27	1.05	1.03
ascorbate	ME1013140	0.91	0.91	0.99	1.19	1.27	0.88	1.13	0.90	1.07
N.METHYLASPARTATE	ME1013214	0.77	0.85	0.89	1.34	1.29	0.91	1.41	1.34	0.84
Itaconic.Acid	ME1013157	1.00	0.82	0.98	1.17	1.09	1.04	1.29	1.21	0.77
OXALATE	ME1013166	0.83	0.85	1.03	1.36	1.30	0.97	1.03	1.21	0.73
4.PYRIDOXATE	ME1013100	0.85	0.88	0.91	1.23	1.29	1.02	1.07	1.23	1.00
quinolinic_acid	ME1013172	0.88	0.83	0.97	1.21	1.28	1.07	1.07	1.19	0.95
anthranilic_acid	ME1013139	0.89	0.76	0.96	1.14	1.41	1.13	0.90	1.31	1.11
GLUCONATE	ME1013148	0.73	0.82	0.88	1.06	1.44	1.27	1.06	1.26	1.23
glycine	ME1013119	1.08	0.94	1.00	1.14	0.95	0.99	1.02	1.12	0.84
beta.alanine	ME1013191	1.01	1.02	1.06	0.90	0.99	0.99	0.84	1.02	0.98
hypoxanthine	ME1013153	1.14	0.96	0.94	0.96	0.99	1.02	1.06	1.02	1.04
asymmetric.dimethylarginine..ADMA.	ME1013108	1.00	1.00	0.98	0.99	1.07	0.98	1.04	0.96	1.01
kynurenine	ME1013210	0.94	0.98	1.01	1.07	1.10	0.91	1.04	1.03	0.98
trans.urocanate	ME1013227	1.01	0.81	0.76	1.10	1.24	1.30	1.37	1.20	1.07
4.ACETAMIDOBUTANOATE	ME1013136	0.95	0.92	0.91	1.15	1.14	1.15	0.84	1.16	1.15
creatinine	ME1013141	1.01	0.92	0.90	1.08	1.03	1.13	1.07	1.12	1.12
THREITOL.ERYTHRITOL	ME1013178	1.02	0.93	0.87	1.12	1.05	1.14	0.99	1.16	1.11
ornithine	ME1013165	1.08	0.90	0.96	1.08	0.97	1.13	0.96	1.19	0.98
proline	ME1013170	1.02	0.92	0.94	1.18	0.99	1.12	0.92	1.15	1.04
valine	ME1013183	1.03	0.88	0.90	1.21	1.00	1.16	0.99	1.18	1.07
uracil	ME1013180	0.70	0.98	0.94	1.11	1.09	1.12	1.12	1.13	1.11
Kynurenic.Acid	ME1013158	0.91	0.91	0.91	1.12	1.17	1.13	1.22	0.88	1.18
glycerate	ME1013150	0.94	0.83	0.79	1.12	1.10	1.26	1.25	1.15	1.34
STACHYOSE	ME1013225	0.96	0.84	0.84	1.03	1.08	1.23	1.31	1.03	1.31
Alpha.Ketoglutarate	ME1013138	0.93	0.91	0.86	1.19	1.06	1.22	1.00	1.04	1.27
N.ACETYLGALACTOSAMINE	ME1013213	0.97	0.94	0.80	1.12	1.25	1.22	0.99	1.07	1.17
glucose	ME1013149	0.94	0.80	0.83	1.27	1.14	1.21	1.12	1.27	1.19
myo.inositol	ME1013162	0.95	0.86	0.88	1.27	1.09	1.15	1.11	1.19	1.08
OXOPROLINE	ME1013217	0.86	0.88	0.77	1.14	1.26	1.19	1.18	1.16	1.35
3.hydroxy.iso.butyric_acid	ME1013134	0.84	0.87	0.75	1.21	1.27	1.28	1.30	1.19	1.14
Methionine.sulfoxide	ME1013093	0.84	0.81	0.82	1.19	1.29	1.17	1.25	1.24	1.20
Pyridoxine	ME1013096	0.86	0.83	0.82	1.14	1.22	1.23	1.26	1.17	1.24
serine	ME1013125	0.90	0.81	0.79	1.19	1.21	1.23	1.23	1.22	1.26
2.oxobutyric_acid	ME1013132	0.94	0.85	0.79	1.22	1.18	1.27	1.24	1.17	1.11
succinate	ME1013176	0.89	0.86	0.82	1.18	1.16	1.21	1.19	1.16	1.22
Butyrylcarnitine	ME1013193	0.92	0.85	0.84	1.18	1.20	1.19	1.19	1.16	1.14
carnitine	ME1013195	0.92	0.85	0.87	1.16	1.17	1.15	1.20	1.16	1.13
biotin	ME1013109	1.02	0.87	0.84	1.06	1.31	1.12	1.17	1.05	1.15
propionylcarnitine	ME1013222	0.85	0.98	0.98	1.04	1.07	1.09	1.09	1.04	1.03
2.hydroxybutyric_acid	ME1013130	0.98	0.94	0.91	1.08	1.09	1.04	1.11	1.12	1.06
homocitrulline	ME1013207	0.91	0.96	0.93	1.05	1.10	1.08	1.11	1.07	1.06
acetylcarnitine	ME1013101	0.97	0.91	0.94	1.05	1.12	1.06	1.09	1.07	1.10
N.acetyllysine	ME1013094	0.97	0.93	0.95	1.05	1.07	1.06	1.11	1.04	1.10
4.GUANIDINOBUTANOATE	ME1013187	0.86	0.87	0.93	1.08	1.18	1.12	1.17	1.09	1.18
fumarate	ME1013145	0.86	0.89	0.89	1.14	1.11	1.17	1.19	1.06	1.20
leucine	ME1013159	0.98	0.88	0.86	1.13	1.09	1.14	1.13	1.19	1.13
mannose.tagatose	ME1013161	0.94	0.89	0.86	1.12	1.03	1.19	1.13	1.17	1.20
biotin.1	ME1013192	0.92	0.92	0.90	1.01	1.13	1.16	1.06	1.11	1.19
hydroxyproline_gammaALA	ME1013209	0.95	0.88	0.89	1.04	1.14	1.14	1.11	1.09	1.23
isoleucine	ME1013120	0.96	0.87	0.90	1.06	1.13	1.17	1.09	1.14	1.17
threonine	ME1013126	0.95	0.87	0.91	1.09	1.09	1.14	1.12	1.13	1.19
phenylalanine	ME1013124	0.95	0.90	0.90	1.07	1.11	1.14	1.12	1.10	1.14
methionine	ME1013122	0.95	0.89	0.90	1.05	1.09	1.15	1.12	1.10	1.17
tryptophan	ME1013127	0.95	0.90	0.89	1.06	1.10	1.13	1.13	1.11	1.17
lysine	ME1013121	0.96	0.89	0.89	1.10	1.10	1.13	1.10	1.13	1.14
sorbitol	ME1013175	0.96	0.90	0.88	1.09	1.10	1.12	1.15	1.12	1.14
asparagine	ME1013106	0.93	0.93	0.91	1.06	1.10	1.09	1.09	1.12	1.14
GALACTARATE	ME1013146	0.98	0.93	0.88	1.03	1.10	1.11	1.12	1.09	1.14
histidine	ME1013152	0.96	0.93	0.89	1.03	1.11	1.07	1.13	1.10	1.18
cystathionine	ME1013196	0.93	0.91	0.86	1.08	1.13	1.20	1.15	1.15	1.10
3.METHYL.L.HISTIDINE	ME1013098	0.93	0.87	0.85	1.11	1.11	1.17	1.23	1.15	1.18
carnosine	ME1013110	0.92	0.92	0.85	1.03	1.16	1.15	1.15	1.15	1.17
sarcosine_unc	ME1013224	0.93	0.87	0.87	1.11	1.15	1.19	1.15	1.11	1.16
LEUCINE	ME1013211	0.92	0.86	0.88	1.11	1.16	1.17	1.17	1.14	1.16
PANTOTHENATE	ME1013218	0.93	0.85	0.89	1.11	1.19	1.16	1.17	1.12	1.15
arginine	ME1013104	0.91	0.89	0.91	1.08	1.14	1.11	1.14	1.10	1.17
Pipecolate	ME1013221	0.91	0.89	0.90	1.06	1.16	1.14	1.15	1.12	1.15
Pantothenate	ME1013168	0.93	0.90	0.86	1.10	1.12	1.12	1.18	1.15	1.14
folic_acid	ME1013116	0.96	0.88	0.87	1.10	1.15	1.12	1.16	1.10	1.19
hydroxyproline.aminolevulinate	ME1013208	0.94	0.89	0.86	1.09	1.14	1.15	1.18	1.13	1.18
tyrosine	ME1013128	0.94	0.88	0.88	1.09	1.12	1.13	1.16	1.13	1.18
creatine	ME1013112	0.89	0.92	0.92	1.08	1.05	1.07	1.16	1.13	1.16
1.METHYL.L.HISTIDINE	ME1013129	0.92	0.93	0.92	1.13	1.07	1.11	1.11	1.11	1.04
DEOXYCARNITINE	ME1013198	0.94	0.87	0.90	1.14	1.12	1.12	1.18	1.13	1.10
indolelactate	ME1013155	0.93	0.93	0.89	1.08	1.15	1.08	1.14	1.12	1.09
aspartate	ME1013107	0.88	0.88	0.94	1.12	1.13	1.10	1.11	1.14	1.11
C5.Carnitines	ME1013194	0.89	0.91	0.90	1.11	1.12	1.12	1.13	1.14	1.09
anserine	ME1013103	0.91	0.89	0.81	1.06	1.15	1.29	1.23	1.10	1.21
cystine	ME1013113	0.93	0.85	0.83	1.10	1.17	1.19	1.16	1.13	1.31
citrulline	ME1013111	0.94	0.85	0.83	1.07	1.20	1.16	1.22	1.15	1.25
GUANIDINOSUCCINATE	ME1013205	0.90	0.88	0.86	1.06	1.18	1.15	1.15	1.15	1.22
glutamine	ME1013118	0.94	0.85	0.87	1.09	1.16	1.17	1.15	1.15	1.23
guanidinoacetate	ME1013204	0.94	0.87	0.84	1.10	1.15	1.18	1.18	1.13	1.23
niacinamide	ME1013123	0.92	0.89	0.88	1.00	1.10	1.16	1.19	1.07	1.27
TARTRATE	ME1013177	0.93	0.88	0.82	1.09	1.13	1.15	1.26	1.08	1.31
Glycerol.3.Phosphate	ME1013151	1.43	1.20	1.32	0.62	0.60	0.65	0.66	0.64	0.63
Ribose.1.phosphate	ME1013173	1.45	0.90	0.85	0.98	0.92	1.04	1.03	1.04	1.06
uridine	ME1013182	1.33	0.99	1.01	0.98	0.90	0.92	0.86	0.95	0.88
GLUCOSAMINE.6.PHOSPHATE	ME1013201	0.96	1.17	1.14	0.81	1.08	0.82	0.86	0.91	0.64
cytidine	ME1013114	1.09	1.14	1.15	0.76	0.84	0.85	0.86	0.81	0.86
cytosine_unc	ME1013115	1.06	1.13	1.14	0.79	0.87	0.86	0.88	0.82	0.90
malate	ME1013160	1.11	1.17	1.20	0.82	0.83	0.75	0.82	0.78	0.72
xanthine	ME1013184	1.09	1.16	1.25	0.74	0.78	0.76	0.76	0.81	0.78
N.acetylphenylalanine	ME1013164	0.95	1.08	1.06	0.95	0.95	0.89	1.00	0.95	0.91
uric.acid	ME1013181	1.03	1.06	1.06	0.90	0.88	0.91	1.05	0.87	0.99
gamma.aminobutyric_acid	ME1013147	0.88	1.18	1.21	0.84	0.84	0.81	0.83	0.85	0.86
alanine	ME1013189	0.91	1.08	1.15	0.88	0.90	0.92	0.91	0.90	0.93
glutamate	ME1013117	0.92	1.15	1.11	0.80	0.88	0.90	0.91	0.87	0.98
3.phosphoglycerate	ME1013099	3.12	1.36	1.51	0.04	0.04	0.04	0.04	0.04	0.03
phosphoenolpyruvate	ME1013169	3.05	1.38	1.52	0.04	0.04	0.04	0.04	0.04	0.03
acetylaspartate	ME1013188	0.37	1.83	2.12	0.12	0.08	0.20	0.15	0.15	0.38
Pyridoxal	ME1013095	1.83	1.56	1.44	0.26	0.23	0.29	0.31	0.31	0.33
S.Adenosyl.L.methionine	ME1013223	2.03	1.34	1.47	0.31	0.35	0.34	0.33	0.34	0.34
Glycerophosphocholine	ME1013092	0.94	1.51	1.49	0.48	0.51	0.51	0.55	0.49	0.54
1.METHYLADENOSINE	ME1013185	1.16	1.57	1.59	0.37	0.38	0.39	0.39	0.37	0.37
argininosuccinate	ME1013105	1.22	1.68	1.62	0.27	0.30	0.28	0.30	0.30	0.30
3.methyl.2.oxopentanoic_acid	ME1013135	1.23	1.90	1.82	0.08	0.07	0.08	0.08	0.08	0.09
CMP	ME1013088	1.04	2.01	1.86	0.05	0.05	0.06	0.06	0.05	0.07
Glucose.6.phosphate	ME1013091	1.13	1.99	1.91	0.02	0.02	0.02	0.02	0.02	0.02
pyruvate	ME1013171	0.88	1.95	1.87	0.18	0.16	0.10	0.11	0.14	0.05
phosphocholine	ME1013219	1.12	1.85	1.71	0.15	0.18	0.16	0.18	0.33	0.17
CDP	ME1013087	1.09	1.87	1.82	0.13	0.12	0.14	0.14	0.13	0.14
phosphocholine.tail	ME1013220	1.11	1.91	1.73	0.14	0.15	0.12	0.19	0.20	0.11
guanine	ME1013206	1.52	1.90	1.82	0.01	0.01	0.01	0.01	0.01	0.01
methylthioadenosine	ME1013212	1.47	1.71	1.80	0.09	0.10	0.12	0.14	0.12	0.18
FRUCTOSE.6.PHOSPHATE.glucose.1.phosphate	ME1013144	1.76	1.70	1.66	0.17	0.11	0.10	0.13	0.15	0.10
Sedoheptulose.7.phosphate	ME1013174	1.69	1.79	1.74	0.06	0.06	0.07	0.06	0.06	0.07

Factors:

F1	Sample source:human CAR-T cell media \| Stimulation:CART acute
F2	Sample source:human CAR-T cell media \| Stimulation:CART chronic
F3	Sample source:human CAR-T cell media \| Stimulation:CART chronic +78c
F4	Sample source:RPMI control media \| Stimulation:RPMI
F5	Sample source:RPMI control media \| Stimulation:RPMI+78c
F6	Sample source:RPMI control media \| Stimulation:RPMI+aFAS
F7	Sample source:RPMI control media \| Stimulation:RPMI+CD3/CD38
F8	Sample source:RPMI control media \| Stimulation:RPMI+DMSO
F9	Sample source:RPMI control media \| Stimulation:RPMI+IL-2

Data matrix