Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003981)

(Analysis AN006557)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8
L-Arginine_C13-label-1	ME1051113	0.73	5.97	0.49	7.14	0.03	0.02	0.11	0.07
L-Lysine_PARENT	ME1051152	1.16	6.90	0.64	7.05	0.02	0.02	0.02	0.02
L-Lactic_acid_C13-label-1	ME1051059	0.00	1.55	0.00	4.46	0.81	0.98	1.36	0.95
L-Lactic_acid_PARENT	ME1051058	0.78	1.16	0.57	2.99	0.97	0.65	1.34	0.68
L-Glutamic_acid_C13-label-1	ME1051134	2.97	2.31	1.09	2.05	0.03	0.03	0.02	0.03
L-Glutamic_acid_PARENT	ME1051133	2.90	2.94	0.88	2.63	0.04	0.04	0.04	0.04
L-Tyrosine_PARENT	ME1051202	1.49	2.16	1.13	2.20	0.00	NA	0.00	NA
L-Valine_PARENT	ME1051212	1.84	2.18	1.10	1.99	0.00	0.00	0.00	0.00
Hexose bisphosphate_PARENT	ME1051044	2.15	2.53	0.92	2.20	0.01	0.00	0.01	NA
L-Tryptophan_PARENT	ME1051190	2.32	2.84	1.39	2.24	0.07	0.06	0.06	0.06
L-Aspartic_acid_C13-label-1	ME1051125	2.12	3.49	1.42	2.68	0.03	0.03	0.01	0.04
L-Aspartic_acid_PARENT	ME1051124	1.99	3.31	1.38	2.67	0.11	0.12	0.10	0.12
3-Phosphoglyceric_acid_PARENT	ME1051025	2.38	1.79	1.39	3.12	0.06	0.04	0.05	0.06
L-Valine_C13-label-1	ME1051213	2.28	2.39	1.42	3.00	0.04	0.01	0.04	0.02
L-Phenylalanine_PARENT	ME1051165	2.04	2.65	1.58	3.09	0.02	0.02	0.02	0.02
L-Methionine_PARENT	ME1051159	2.15	2.53	1.64	2.64	0.01	0.00	0.00	0.00
Ile_Leu_C13-label-1	ME1051102	2.08	2.57	1.62	2.79	0.02	0.02	0.02	0.02
Ile_Leu_PARENT	ME1051101	2.10	2.56	1.64	2.82	0.00	0.00	0.00	0.00
L-Phenylalanine_C13-label-1	ME1051166	1.95	2.93	1.46	3.56	0.03	0.03	0.04	0.03
L-Phenylalanine_C13-label-2	ME1051167	1.81	2.67	1.23	3.38	0.06	0.12	0.05	NA
Coenzyme_A_C13-label-1	ME1051243	0.98	2.73	1.06	4.04	0.00	NA	0.00	NA
Acetyl-CoA_C13-label-1	ME1051219	0.57	2.45	0.80	4.24	0.00	NA	0.00	NA
Acetyl-CoA_PARENT	ME1051218	0.41	2.43	0.56	4.14	NA	NA	NA	NA
L-Alanine_C13-label-1	ME1051109	0.70	2.57	0.50	3.11	NA	NA	NA	NA
Coenzyme_A_C13-label-3	ME1051245	0.69	2.90	0.46	3.07	NA	NA	NA	NA
Hexose_C13-label-5	ME1051042	0.64	3.02	0.41	3.35	NA	NA	NA	NA
L-Asparagine_C13-label-1	ME1051120	0.93	2.54	0.49	2.29	NA	NA	NA	NA
L-Histidine_C13-label-1	ME1051146	0.85	2.71	0.41	2.81	NA	NA	NA	NA
L-Serine_C13-label-1	ME1051182	1.00	2.57	0.55	2.69	0.01	NA	NA	NA
L-Glutamine_C13-label-2	ME1051141	1.11	2.07	0.47	2.02	NA	0.05	NA	NA
Coenzyme_A_C13-label-2	ME1051244	0.64	1.95	0.71	2.94	NA	NA	NA	NA
Glycine_C13-label-1	ME1051099	0.89	1.60	0.40	2.62	NA	NA	NA	NA
Coenzyme_A_PARENT	ME1051242	1.36	3.67	1.45	5.61	0.01	0.00	0.00	0.00
L-Arginine_PARENT	ME1051112	1.27	5.72	0.96	6.35	0.00	0.00	0.00	0.01
L-Alanine_PARENT	ME1051108	1.51	4.65	1.07	5.85	0.01	0.01	0.01	0.01
L-Histidine_PARENT	ME1051145	1.65	5.17	0.93	5.31	0.03	0.03	0.02	0.03
L-Lysine_C13-label-1	ME1051153	0.60	4.29	0.24	4.12	NA	NA	NA	0.00
L-Glutamine_C13-label-1	ME1051140	2.31	4.33	0.98	3.34	0.02	0.02	0.01	0.01
L-Glutamine_PARENT	ME1051139	2.31	4.43	0.99	3.19	0.02	0.02	0.01	0.01
L-Threonine_C13-label-1	ME1051186	1.54	4.17	0.78	3.69	0.01	NA	0.01	NA
L-Tyrosine_C13-label-1	ME1051203	1.70	3.47	0.88	3.31	0.00	NA	0.00	0.00
L-Asparagine_PARENT	ME1051119	1.87	5.03	0.99	4.49	0.00	0.00	0.00	0.00
L-Threonine_PARENT	ME1051185	1.90	4.90	1.00	4.45	0.01	0.00	0.01	0.00
Dihydroxyacetone_phosphate_PARENT	ME1051033	2.46	3.86	0.80	4.14	0.01	0.03	0.01	0.02
Glycine_PARENT	ME1051098	1.70	3.96	1.12	4.25	0.12	0.11	0.13	0.13
L-Serine_PARENT	ME1051181	1.82	4.28	1.15	4.51	0.02	0.02	0.02	0.02
Fumaric_acid_PARENT	ME1051077	0.11	0.09	0.17	0.08	2.06	1.34	1.20	2.40
Hexose-phosphate_C13-label-4	ME1051055	1.13	0.01	1.21	NA	1.15	0.00	1.16	0.00
Oxoglutaric_acid_C13-label-5	ME1051092	1.47	0.00	3.14	0.00	0.04	0.00	0.05	0.00
L-Malic_acid_C13-label-4	ME1051086	1.36	0.00	3.30	0.00	0.01	0.00	0.01	0.00
Succinic_acid_C13-label-4	ME1051097	1.40	0.00	3.27	0.00	0.01	0.00	0.01	0.00
Citric_acid_C13-label-3	ME1051073	2.44	0.03	2.19	0.06	0.02	NA	0.02	0.00
Fumaric_acid_C13-label-3	ME1051080	1.41	0.00	2.47	NA	0.00	0.00	0.00	0.00
Succinic_acid_C13-label-2	ME1051095	2.18	0.00	2.45	NA	0.00	0.00	0.00	0.00
Citric_acid_C13-label-4	ME1051074	2.28	0.04	2.49	0.08	0.03	0.00	0.04	0.00
Citric_acid_C13-label-5	ME1051075	2.25	0.03	2.52	0.07	0.02	0.00	0.04	0.00
L-Glutamic_acid_C13-label-5	ME1051138	2.02	0.01	2.45	NA	0.08	0.01	0.06	0.03
L-Lactic_acid_C13-label-2	ME1051060	2.07	0.06	2.64	0.07	0.05	0.01	0.04	0.02
L-Lactic_acid_C13-label-3	ME1051061	2.10	0.03	2.68	0.03	0.02	0.00	0.01	0.01
L-Malic_acid_C13-label-2	ME1051084	2.05	0.02	2.69	0.02	0.03	0.02	0.03	0.02
Citric_acid_C13-label-6	ME1051076	1.83	0.03	2.67	0.07	0.02	NA	0.03	0.00
Oxoglutaric_acid_C13-label-4	ME1051091	1.62	NA	2.58	0.00	0.06	0.00	0.06	NA
Oxoglutaric_acid_C13-label-3	ME1051090	1.67	0.09	2.87	0.13	0.07	0.06	0.06	0.07
L-Malic_acid_C13-label-3	ME1051085	1.82	0.00	2.93	0.00	0.01	0.00	0.01	0.00
Succinic_acid_C13-label-3	ME1051096	1.84	0.00	2.91	0.00	0.01	0.00	0.01	0.00
Fumaric_acid_C13-label-4	ME1051081	0.74	0.00	2.01	0.00	0.00	NA	0.00	NA
Acetyl-CoA_C13-label-2	ME1051220	0.92	0.05	1.44	0.08	NA	NA	NA	NA
Acetyl-CoA_C13-label-3	ME1051221	0.94	0.01	1.45	0.02	NA	NA	NA	NA
Fumaric_acid_C13-label-2	ME1051079	1.31	0.00	1.75	NA	0.01	NA	0.00	0.00
Hexose-phosphate_C13-label-6	ME1051057	1.35	NA	1.91	0.02	0.01	NA	0.01	0.01
Pyruvic_acid_C13-label-2	ME1051068	1.94	0.01	1.99	0.03	0.48	0.00	0.46	0.00
Pyruvic_acid_C13-label-3	ME1051069	1.94	0.01	2.00	0.03	0.48	0.00	0.46	0.00
L-Glutamic_acid_C13-label-3	ME1051136	1.84	NA	1.72	NA	0.01	NA	0.00	NA
L-Glutamic_acid_C13-label-4	ME1051137	2.13	NA	1.88	NA	0.01	NA	0.00	NA
L-Aspartic_acid_C13-label-4	ME1051128	1.80	NA	1.33	NA	0.02	NA	0.03	0.02
Oxoglutaric_acid_C13-label-2	ME1051089	2.25	NA	1.20	0.00	0.00	0.00	0.00	0.00
3-Phosphoglyceric_acid_C13-label-3	ME1051028	2.12	NA	0.49	0.03	0.04	NA	NA	NA
Citric_acid_C13-label-2	ME1051072	3.73	0.05	1.35	0.09	0.02	0.00	0.02	0.01
L-Alanine_C13-label-3	ME1051111	2.78	NA	1.35	NA	0.02	NA	0.01	NA
L-Aspartic_acid_C13-label-3	ME1051127	3.20	0.07	0.95	0.05	0.07	NA	0.03	0.03
L-Glutamic_acid_C13-label-2	ME1051135	3.21	0.01	1.22	0.01	0.01	NA	0.00	NA
Hexose-phosphate_PARENT	ME1051051	1.18	0.93	2.72	2.67	0.01	0.01	0.01	0.01
Hexose_C13-label-1	ME1051038	0.75	0.54	2.24	3.12	0.02	0.01	0.03	0.02
Hexose_PARENT	ME1051037	0.80	0.60	1.92	2.57	0.01	NA	0.01	0.00
Hexose-phosphate_C13-label-1	ME1051052	0.80	0.73	2.29	2.50	0.35	0.00	0.34	NA
Pyruvic_acid_C13-label-1	ME1051067	0.74	1.38	0.74	1.35	1.10	1.38	1.10	1.35
Pyruvic_acid_PARENT	ME1051066	0.60	1.51	0.58	1.50	1.18	1.53	1.18	1.52
Fumaric_acid_C13-label-1	ME1051078	0.91	0.54	1.15	0.90	1.11	1.11	0.93	0.97
L-Malic_acid_PARENT	ME1051082	1.53	1.20	1.08	1.07	0.75	0.72	0.74	0.76
Oxoglutaric_acid_C13-label-1	ME1051088	1.37	0.92	1.16	1.07	0.80	0.73	0.78	0.90
Oxoglutaric_acid_PARENT	ME1051087	1.27	0.96	1.03	1.07	0.86	0.82	0.89	1.03
Ile_Leu_C13-label-2	ME1051103	1.17	1.44	0.85	1.60	NA	NA	0.00	NA
L-Methionine_C13-label-1	ME1051160	1.19	1.52	0.86	1.41	NA	NA	0.02	NA
3-Phosphoglyceric_acid_C13-label-1	ME1051026	1.70	0.83	0.67	1.99	0.03	NA	NA	NA
Phosphoenolpyruvic_acid_PARENT	ME1051062	1.49	1.12	0.83	1.68	0.04	NA	0.00	NA
L-Malic_acid_C13-label-1	ME1051083	1.65	0.83	1.58	0.75	0.55	0.53	0.54	0.51
Succinic_acid_C13-label-1	ME1051094	2.09	0.62	1.81	0.62	0.31	0.28	0.30	0.28
Succinic_acid_PARENT	ME1051093	2.05	1.19	1.16	1.19	0.50	0.50	0.52	0.49
Citric_acid_C13-label-1	ME1051071	2.68	1.28	1.29	0.87	0.24	0.22	0.26	0.21
Citric_acid_PARENT	ME1051070	2.48	1.58	1.19	1.02	0.32	0.30	0.34	0.30

Factors:

F1	Sample source:Liver mitochondria \| Treatment condition:CLP \| Tracer condition:13C pyruvate
F2	Sample source:Liver mitochondria \| Treatment condition:CLP \| Tracer condition:Buffer
F3	Sample source:Liver mitochondria \| Treatment condition:Sham \| Tracer condition:13C pyruvate
F4	Sample source:Liver mitochondria \| Treatment condition:Sham \| Tracer condition:Buffer
F5	Sample source:mitochondria supernatant \| Treatment condition:CLP \| Tracer condition:13C pyruvate
F6	Sample source:mitochondria supernatant \| Treatment condition:CLP \| Tracer condition:Buffer
F7	Sample source:mitochondria supernatant \| Treatment condition:Sham \| Tracer condition:13C pyruvate
F8	Sample source:mitochondria supernatant \| Treatment condition:Sham \| Tracer condition:Buffer

Data matrix