Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003983)

HILIC NEGATIVE ION MODE (Analysis AN006559)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12	F13	F14	F15	F16	F17	F18	F19	F20
L-Malic acid_PARENT	ME1051355	1.33	2.44	1.00	1.16	2.07	0.84	1.07	0.02	0.02	NA	0.00	NA	NA	NA	NA	NA	0.03	0.04	0.01	NA
Succinic acid_PARENT	ME1051366	2.14	2.88	2.24	1.69	2.03	2.30	2.56	2.62	0.22	0.13	0.20	0.18	0.18	0.16	0.16	0.15	0.12	0.10	0.11	0.08
L-Alanine_PARENT	ME1051376	2.26	2.50	2.25	2.73	1.95	1.94	1.19	1.89	0.37	0.39	0.33	0.51	0.04	0.01	0.02	0.03	0.76	0.69	0.55	0.71
L-Lactic acid_PARENT	ME1051331	2.42	2.25	1.81	2.05	1.42	1.55	1.38	1.67	0.52	0.45	0.43	0.60	0.21	0.14	0.22	0.23	0.73	0.80	0.74	0.84
L-Aspartic acid_PARENT	ME1051397	0.27	0.70	0.73	0.46	1.36	3.22	1.72	2.94	0.40	0.75	0.70	0.99	0.03	0.01	0.02	0.02	1.26	2.35	2.55	3.37
L-Glutamic acid_PARENT	ME1051385	0.49	0.75	1.67	1.23	2.11	2.94	2.44	3.39	0.30	0.41	0.37	0.49	0.03	0.02	0.02	0.02	0.74	1.49	1.37	1.52
L-Asparagine_C13-label-1	ME1051381	1.66	1.45	1.17	1.25	2.88	3.83	1.16	2.36	0.35	0.49	0.32	0.45	0.04	0.04	0.02	0.05	1.25	1.27	0.70	1.04
L-Asparagine_PARENT	ME1051380	1.28	1.50	1.04	1.33	3.10	4.14	1.21	2.64	0.31	0.55	0.27	0.51	0.05	0.03	0.04	0.05	1.30	1.43	0.73	1.16
Succinic acid_C13-label-1	ME1051367	2.73	0.93	1.92	0.59	3.55	0.74	2.42	0.94	0.27	0.04	0.11	0.06	0.11	0.05	0.06	0.05	0.09	0.03	0.05	0.02
Succinic acid_C13-label-2	ME1051368	2.54	0.04	1.64	0.05	4.31	0.01	2.81	0.11	0.34	0.00	0.07	0.00	0.12	0.00	0.02	0.00	0.10	0.00	0.02	0.00
Succinic acid_C13-label-3	ME1051369	1.68	0.00	0.66	NA	4.69	0.01	2.87	0.01	0.25	NA	0.03	NA	0.11	NA	0.01	NA	0.09	NA	0.01	NA
L-Alanine_C13-label-1	ME1051377	2.50	1.42	2.14	1.59	2.30	1.05	1.23	1.04	0.63	0.20	0.37	0.29	0.07	0.01	0.02	0.02	0.92	0.37	0.53	0.40
L-Lactic acid_C13-label-1	ME1051332	1.90	0.93	1.32	0.88	2.53	0.64	1.36	0.73	0.86	0.19	0.43	0.26	0.40	0.06	0.24	0.11	1.33	0.33	0.72	0.37
L-Alanine_C13-label-2	ME1051378	2.68	0.03	2.21	0.11	2.52	0.02	1.27	0.10	0.97	0.01	0.44	0.03	0.12	0.00	0.03	0.01	1.20	0.01	0.48	0.03
L-Alanine_C13-label-3	ME1051379	2.20	NA	1.91	0.03	2.28	NA	1.17	0.06	0.93	NA	0.39	0.02	0.11	NA	0.03	NA	1.27	NA	0.49	0.03
L-Lactic acid_C13-label-2	ME1051333	1.56	0.02	1.11	0.08	3.05	0.01	1.40	0.05	1.07	0.01	0.47	0.03	0.55	0.00	0.28	0.01	1.73	0.01	0.74	0.03
L-Lactic acid_C13-label-3	ME1051334	1.42	0.00	1.06	0.03	2.22	0.00	2.68	0.01	1.02	0.01	0.55	0.02	0.51	0.00	0.27	0.00	1.50	0.01	0.76	0.01
Citric acid_PARENT	ME1051343	0.84	0.60	0.87	1.05	2.25	1.41	2.59	1.48	0.59	0.45	0.61	0.45	0.14	0.07	0.15	0.08	1.34	1.41	1.03	1.03
L-Glutamic acid_C13-label-1	ME1051386	0.69	0.30	1.60	0.53	2.80	1.17	2.38	1.54	0.48	0.17	0.33	0.21	0.03	0.01	0.01	0.01	1.12	0.59	1.51	0.69
Citric acid_C13-label-1	ME1051344	0.93	0.40	0.66	0.51	3.28	1.15	2.32	0.98	0.73	0.34	0.51	0.30	0.11	0.05	0.10	0.05	1.52	0.76	0.82	0.55
Citric acid_C13-label-4	ME1051347	0.41	0.15	0.19	0.12	3.98	1.09	3.16	0.75	0.83	0.37	0.34	0.27	0.13	0.06	0.09	0.04	1.53	0.47	0.59	0.30
Citric acid_C13-label-2	ME1051345	0.78	0.23	0.47	0.17	3.84	1.01	2.41	0.71	0.85	0.31	0.42	0.22	0.10	0.04	0.08	0.04	1.75	0.46	0.61	0.29
Citric acid_C13-label-3	ME1051346	0.54	0.17	0.23	0.12	4.30	1.13	2.62	0.75	0.86	0.33	0.36	0.23	0.11	0.05	0.08	0.04	1.65	0.46	0.54	0.28
L-Glutamic acid_C13-label-2	ME1051387	0.72	0.01	1.46	0.04	3.80	0.02	2.32	0.21	0.63	0.01	0.21	0.02	0.03	0.00	0.01	0.00	1.75	0.02	0.99	0.06
L-Glutamic acid_C13-label-3	ME1051388	0.48	NA	0.51	0.00	4.36	NA	2.66	0.08	0.64	NA	0.13	0.00	0.03	NA	0.01	0.00	1.48	NA	0.67	0.00
L-Glutamic acid_C13-label-4	ME1051389	0.37	NA	0.32	NA	3.61	NA	3.05	NA	0.51	NA	0.08	NA	0.03	NA	0.02	NA	1.52	NA	0.49	NA
L-Aspartic acid_C13-label-1	ME1051398	0.37	0.24	0.66	0.16	1.92	1.13	1.62	1.12	0.60	0.26	0.60	0.38	0.02	0.00	0.01	0.01	1.92	0.83	3.18	1.43
L-Aspartic acid_C13-label-3	ME1051400	0.22	NA	0.22	NA	2.45	NA	1.56	0.01	0.86	NA	0.43	NA	0.03	NA	0.01	0.00	3.11	NA	1.51	NA
L-Aspartic acid_C13-label-2	ME1051399	0.37	0.01	0.60	0.02	2.19	0.04	1.49	0.12	0.82	0.01	0.42	0.04	0.02	NA	0.01	0.00	3.14	0.03	2.65	0.18
L-Aspartic acid_C13-label-4	ME1051401	0.12	NA	0.02	NA	2.23	NA	1.18	NA	0.94	NA	0.31	NA	0.03	NA	0.01	NA	2.40	NA	2.37	NA
Fumaric acid_C13-label-1	ME1051351	2.15	0.66	1.23	0.37	1.73	0.39	0.76	0.12	1.70	0.49	0.63	0.35	0.02	0.00	0.01	0.00	1.89	0.56	1.19	0.49
Fumaric acid_C13-label-4	ME1051354	0.48	NA	0.04	NA	1.18	NA	1.28	NA	2.43	0.04	0.30	0.02	0.05	NA	0.02	NA	2.24	NA	0.63	0.02
Fumaric acid_C13-label-2	ME1051352	1.44	NA	0.62	NA	1.36	NA	0.38	NA	1.87	0.05	0.31	0.01	NA	NA	NA	NA	2.15	0.10	0.62	0.06
Fumaric acid_C13-label-3	ME1051353	1.23	NA	0.30	NA	1.86	0.01	1.04	NA	2.30	0.14	0.37	0.02	0.02	NA	0.00	NA	2.84	0.10	0.58	0.01
Pyruvic acid_C13-label-3	ME1051342	0.07	NA	0.01	NA	0.14	NA	6.21	NA	0.70	NA	0.18	0.00	0.53	NA	1.04	0.02	1.43	NA	0.28	0.00
Citric acid_C13-label-5	ME1051348	0.29	0.06	0.12	0.03	3.71	1.12	4.34	0.80	0.67	0.30	0.30	0.21	0.07	0.01	0.03	0.00	1.21	0.41	0.63	0.26
Citric acid_C13-label-6	ME1051349	0.11	0.01	0.03	0.00	3.07	1.02	5.03	0.69	0.42	0.07	0.06	0.03	0.01	0.00	0.00	0.00	0.87	0.10	0.62	0.02
L-Glutamic acid_C13-label-5	ME1051390	0.24	NA	0.22	NA	3.28	NA	4.60	0.01	0.35	NA	0.03	NA	0.01	NA	0.01	NA	0.69	NA	0.56	NA
Succinic acid_C13-label-4	ME1051370	0.61	NA	0.09	NA	2.96	0.00	5.74	NA	0.19	NA	0.02	NA	0.12	NA	0.02	0.00	0.05	NA	0.01	NA
Fumaric acid_PARENT	ME1051350	1.79	2.22	1.57	1.27	1.10	1.34	0.89	0.39	1.08	1.44	0.82	1.07	0.03	0.01	0.02	0.01	1.25	1.79	1.27	1.44
D-Glyceraldehyde 3-phosphate_C13-label-1	ME1051336	0.80	1.16	0.26	0.77	0.04	0.05	NA	NA	1.94	2.13	1.29	2.04	1.01	0.02	0.11	0.03	1.79	1.56	1.47	1.64
D-Glyceraldehyde 3-phosphate_PARENT	ME1051335	1.29	1.78	0.51	1.27	0.17	0.24	0.14	0.23	1.74	2.92	1.45	3.02	0.28	0.10	0.11	0.13	1.70	2.31	1.71	2.47
Oxoglutaric acid_C13-label-1	ME1051361	0.01	NA	0.01	NA	0.00	NA	3.93	NA	3.52	0.59	0.79	0.44	0.83	0.49	0.74	0.17	0.89	0.15	0.27	0.08
Pyruvic acid_C13-label-1	ME1051340	0.21	0.12	0.16	0.20	0.07	0.03	0.62	0.02	1.80	0.57	0.80	0.71	1.24	1.15	2.57	0.96	2.67	0.54	0.90	0.53
Pyruvic acid_C13-label-2	ME1051341	0.06	NA	0.03	NA	0.02	NA	1.60	NA	1.54	0.00	0.45	0.03	1.44	0.01	2.58	0.11	2.77	NA	0.60	0.01
Oxoglutaric acid_PARENT	ME1051360	0.03	0.01	0.03	0.03	0.02	0.01	1.65	0.03	2.84	2.21	1.27	1.54	1.32	1.66	1.49	0.55	1.02	1.33	0.67	0.87
Pyruvic acid_PARENT	ME1051339	0.34	0.27	0.24	0.46	0.11	0.12	0.77	0.07	1.48	1.31	1.01	1.55	0.63	2.50	2.08	1.93	2.09	1.26	1.12	1.17
L-Glutamine_PARENT	ME1051391	3.98	5.55	2.30	3.86	0.93	1.01	0.54	1.01	0.24	0.50	0.32	0.48	0.04	0.07	0.04	0.07	0.46	0.68	0.41	0.52
L-Glutamine_C13-label-1	ME1051392	5.54	2.38	2.17	1.84	0.99	0.43	0.47	0.47	0.38	0.21	0.30	0.22	0.04	0.03	0.03	0.03	0.50	0.29	0.35	0.24
L-Glutamine_C13-label-4	ME1051395	6.80	NA	2.03	0.00	0.40	NA	0.16	NA	0.25	NA	0.11	NA	0.03	NA	0.02	NA	0.26	NA	0.13	NA
L-Glutamine_C13-label-2	ME1051393	7.28	0.04	1.90	0.21	0.91	0.01	0.30	0.04	0.49	0.01	0.21	0.02	0.04	0.00	0.02	0.00	0.55	0.01	0.22	0.02
L-Glutamine_C13-label-3	ME1051394	7.01	NA	1.85	0.06	0.71	NA	0.22	0.00	0.41	NA	0.15	0.01	0.04	NA	0.02	0.00	0.42	NA	0.16	0.00
L-Asparagine_C13-label-2	ME1051382	5.44	0.45	3.40	0.21	0.35	0.18	0.47	0.08	0.19	0.02	0.16	0.01	0.01	NA	0.01	NA	0.25	0.07	0.11	0.07
L-Glutamine_C13-label-5	ME1051396	5.93	NA	2.72	NA	0.33	NA	0.20	NA	0.21	NA	0.14	NA	0.04	NA	0.04	NA	0.22	NA	0.17	NA

Factors:

F1	Sample source:Heart \| Treatment condition:CLP \| Tracer condition:13C pyruvate
F2	Sample source:Heart \| Treatment condition:CLP \| Tracer condition:PBS
F3	Sample source:Heart \| Treatment condition:Sham \| Tracer condition:13C pyruvate
F4	Sample source:Heart \| Treatment condition:Sham \| Tracer condition:PBS
F5	Sample source:Kidney \| Treatment condition:CLP \| Tracer condition:13C pyruvate
F6	Sample source:Kidney \| Treatment condition:CLP \| Tracer condition:PBS
F7	Sample source:Kidney \| Treatment condition:Sham \| Tracer condition:13C pyruvate
F8	Sample source:Kidney \| Treatment condition:Sham \| Tracer condition:PBS
F9	Sample source:Lung \| Treatment condition:CLP \| Tracer condition:13C pyruvate
F10	Sample source:Lung \| Treatment condition:CLP \| Tracer condition:PBS
F11	Sample source:Lung \| Treatment condition:Sham \| Tracer condition:13C pyruvate
F12	Sample source:Lung \| Treatment condition:Sham \| Tracer condition:PBS
F13	Sample source:Red blood cells \| Treatment condition:CLP \| Tracer condition:13C pyruvate
F14	Sample source:Red blood cells \| Treatment condition:CLP \| Tracer condition:PBS
F15	Sample source:Red blood cells \| Treatment condition:Sham \| Tracer condition:13C pyruvate
F16	Sample source:Red blood cells \| Treatment condition:Sham \| Tracer condition:PBS
F17	Sample source:Spleen \| Treatment condition:CLP \| Tracer condition:13C pyruvate
F18	Sample source:Spleen \| Treatment condition:CLP \| Tracer condition:PBS
F19	Sample source:Spleen \| Treatment condition:Sham \| Tracer condition:13C pyruvate
F20	Sample source:Spleen \| Treatment condition:Sham \| Tracer condition:PBS

Data matrix