Clustering data with hclust algorithm for (Study ST004164)
(Analysis AN006912)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 | F19 | F20 | F21 | F22 | F23 | F24 | F25 | F26 | F27 | F28 | F29 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Guanine | ME1115110 | 0.61 | 1.54 | 1.38 | 1.45 | 1.58 | 0.47 | 0.47 | 0.50 | 0.50 | 1.35 | 1.31 | 1.74 | 0.61 | 0.49 | 0.63 | 1.28 | 3.18 | 2.76 | 0.63 | 0.54 | 0.79 | 0.51 | 0.43 | 0.29 | 0.52 | 1.74 | 1.49 | 1.16 | 0.89 |
| Adenosine | ME1115095 | 0.95 | 1.16 | 1.59 | 0.81 | 0.87 | 0.54 | 0.58 | 0.47 | 0.41 | 1.53 | 0.76 | 1.60 | 0.92 | 0.80 | 1.02 | 1.88 | 1.94 | 1.63 | 0.75 | 0.89 | 0.88 | 0.71 | 0.80 | 0.53 | 0.53 | 1.95 | 1.01 | 0.83 | 1.07 |
| Adenine | ME1115094 | 1.10 | 1.37 | 1.32 | 1.18 | 1.28 | 0.60 | 0.56 | 0.51 | 0.71 | 0.82 | 0.89 | 0.99 | 0.83 | 0.72 | 0.87 | 1.14 | 1.70 | 1.52 | 1.08 | 1.53 | 0.97 | 0.68 | 0.88 | 0.57 | 0.90 | 1.32 | 1.25 | 1.05 | 0.98 |
| Cytosine | ME1115103 | 0.94 | 1.52 | 1.65 | 1.48 | 1.28 | 0.67 | 0.70 | 0.70 | 0.49 | 1.01 | 1.11 | 1.45 | 0.83 | 0.54 | 0.75 | 1.18 | 2.21 | 2.21 | 0.70 | 1.20 | 0.88 | 0.46 | 0.37 | 0.52 | 0.70 | 1.22 | 1.27 | 1.04 | 0.94 |
| NAD+ | ME1115113 | 0.97 | 1.01 | 1.34 | 0.83 | 0.93 | 0.96 | 1.01 | 1.49 | 0.91 | 1.81 | 1.86 | 2.00 | 1.18 | 0.83 | 1.04 | 1.03 | 1.83 | 1.27 | 0.74 | 1.19 | 0.66 | 0.49 | 0.72 | 0.42 | 0.90 | 1.60 | 1.20 | 0.92 | 0.82 |
| NADP+ | ME1115115 | 0.85 | 0.90 | 0.99 | 0.68 | 0.82 | 0.73 | 0.81 | 1.24 | 0.60 | 1.27 | 1.43 | 1.42 | 0.98 | 0.82 | 1.06 | 1.10 | 1.74 | 1.28 | 0.64 | 1.24 | 0.98 | 0.94 | 0.87 | 0.70 | 1.05 | 1.16 | 1.12 | 1.07 | 0.94 |
| ADP | ME1115096 | 1.32 | 1.19 | 1.42 | 1.26 | 1.04 | 1.04 | 1.23 | 1.20 | 1.00 | 0.55 | 0.65 | 0.70 | 1.21 | 1.03 | 1.74 | 1.40 | 1.80 | 1.57 | 1.20 | 0.63 | 0.80 | 0.59 | 0.50 | 0.46 | 0.95 | 1.38 | 1.03 | 0.85 | 0.91 |
| AMP | ME1115097 | 1.15 | 0.88 | 1.06 | 0.96 | 1.01 | 0.88 | 0.94 | 1.15 | 1.37 | 0.75 | 0.75 | 0.87 | 1.28 | 1.30 | 1.50 | 1.18 | 1.55 | 1.13 | 1.08 | 0.80 | 0.86 | 0.83 | 0.72 | 0.65 | 0.92 | 0.99 | 0.75 | 0.67 | 1.15 |
| CMP | ME1115100 | 2.11 | 1.27 | 1.33 | 1.03 | 1.21 | 1.36 | 1.19 | 1.44 | 1.54 | 0.90 | 0.91 | 1.05 | 1.21 | 0.87 | 1.36 | 0.95 | 1.24 | 1.04 | 1.48 | 1.06 | 0.67 | 0.60 | 0.79 | 0.70 | 1.25 | 1.35 | 0.71 | 1.00 | 0.73 |
| CTP | ME1115101 | 1.40 | 1.42 | 1.60 | 1.46 | 1.18 | 1.35 | 1.02 | 1.13 | 0.97 | 1.22 | 1.38 | 1.50 | 0.79 | 0.64 | 0.72 | 0.83 | 0.91 | 0.87 | 1.32 | 1.51 | 0.71 | 0.80 | 1.10 | 0.80 | 1.16 | 1.48 | 1.42 | 1.20 | 0.65 |
| Fenclonine (IS) | ME1115092 | 1.05 | 0.78 | 0.88 | 0.84 | 0.79 | 1.06 | 1.08 | 1.02 | 0.98 | 0.75 | 0.76 | 0.82 | 1.09 | 1.05 | 1.04 | 0.85 | 0.76 | 0.88 | 0.99 | 0.75 | 1.08 | 1.24 | 1.14 | 0.99 | 1.27 | 0.99 | 1.04 | 0.97 | 1.10 |
| Total protein | ME1115091 | 0.96 | 1.28 | 0.94 | 0.83 | 0.69 | 1.26 | 0.89 | 0.96 | 0.98 | 1.10 | 1.14 | 0.94 | 0.83 | 1.10 | 0.98 | 0.80 | 1.44 | 0.92 | 1.10 | 0.98 | 1.00 | 1.05 | 0.96 | 0.96 | 0.89 | 0.96 | 1.05 | 1.62 | 0.90 |
| Adenosine diphosphate ribose | ME1115118 | 1.46 | 1.04 | 1.30 | 0.90 | 1.06 | 1.41 | 1.07 | 1.01 | 0.98 | 0.99 | 1.08 | 1.25 | 1.00 | 0.90 | 1.03 | 0.91 | 1.30 | 1.07 | 1.12 | 1.72 | 0.90 | 0.67 | 0.96 | 0.70 | 1.06 | 1.06 | 0.94 | 0.97 | 0.80 |
| GDP | ME1115104 | 1.12 | 1.08 | 1.18 | 1.09 | 1.10 | 1.05 | 0.96 | 1.03 | 1.00 | 0.83 | 0.87 | 1.01 | 1.02 | 0.94 | 1.14 | 1.04 | 1.28 | 1.23 | 1.10 | 0.75 | 0.91 | 0.92 | 0.78 | 0.76 | 0.97 | 1.28 | 1.11 | 1.03 | 0.99 |
| ATP | ME1115098 | 1.17 | 1.18 | 1.20 | 1.12 | 1.02 | 0.90 | 0.83 | 0.88 | 0.89 | 0.98 | 1.04 | 1.07 | 1.09 | 0.96 | 1.04 | 1.18 | 1.17 | 1.11 | 1.02 | 1.09 | 0.95 | 0.60 | 0.85 | 0.71 | 0.95 | 1.09 | 1.07 | 0.94 | 1.04 |
| GSSG | ME1115108 | 1.43 | 1.24 | 1.35 | 1.20 | 1.00 | 1.06 | 0.97 | 1.16 | 1.19 | 0.95 | 1.00 | 1.13 | 1.08 | 0.94 | 1.09 | 0.97 | 0.99 | 0.96 | 1.16 | 1.27 | 0.92 | 0.63 | 0.84 | 0.74 | 1.10 | 1.19 | 1.10 | 0.96 | 0.81 |
| GTP | ME1115109 | 1.33 | 1.23 | 1.31 | 1.16 | 0.96 | 1.03 | 0.84 | 0.96 | 0.94 | 1.02 | 1.13 | 1.12 | 1.09 | 0.89 | 0.97 | 1.06 | 1.07 | 1.00 | 1.17 | 1.26 | 0.90 | 0.67 | 1.02 | 0.74 | 1.10 | 1.15 | 1.08 | 1.02 | 0.89 |
Factors:
| F1 | Sample source:mouse primary astrocytes | Genotype:Ent10 knockout | treatment:TNF𝝰/IL-1𝝰 |
| F2 | Sample source:mouse primary astrocytes | Genotype:Ent11 knockout | treatment:TNF𝝰/IL-1𝝰 |
| F3 | Sample source:mouse primary astrocytes | Genotype:Ent12 knockout | treatment:TNF𝝰/IL-1𝝰 |
| F4 | Sample source:mouse primary astrocytes | Genotype:Ent13 knockout | treatment:TNF𝝰/IL-1𝝰 |
| F5 | Sample source:mouse primary astrocytes | Genotype:Ent14 knockout | treatment:TNF𝝰/IL-1𝝰 |
| F6 | Sample source:mouse primary astrocytes | Genotype:Ent15 knockout | treatment:TNF𝝰/IL-1𝝰/Forodesine |
| F7 | Sample source:mouse primary astrocytes | Genotype:Ent16 knockout | treatment:TNF𝝰/IL-2𝝰/Forodesine |
| F8 | Sample source:mouse primary astrocytes | Genotype:Ent17 knockout | treatment:TNF𝝰/IL-3𝝰/Forodesine |
| F9 | Sample source:mouse primary astrocytes | Genotype:Ent18 knockout | treatment:TNF𝝰/IL-4𝝰/Forodesine |
| F10 | Sample source:mouse primary astrocytes | Genotype:Ent19 knockout | treatment:TNF𝝰/IL-5𝝰/Forodesine |
| F11 | Sample source:mouse primary astrocytes | Genotype:Ent20 knockout | treatment:TNF𝝰/IL-6𝝰/Forodesine |
| F12 | Sample source:mouse primary astrocytes | Genotype:Ent21 knockout | treatment:TNF𝝰/IL-7𝝰/Forodesine |
| F13 | Sample source:mouse primary astrocytes | Genotype:Ent2 knockout | treatment:Vehicle |
| F14 | Sample source:mouse primary astrocytes | Genotype:Ent3 knockout | treatment:Vehicle |
| F15 | Sample source:mouse primary astrocytes | Genotype:Ent4 knockout | treatment:Vehicle |
| F16 | Sample source:mouse primary astrocytes | Genotype:Ent5 knockout | treatment:Vehicle |
| F17 | Sample source:mouse primary astrocytes | Genotype:Ent6 knockout | treatment:Vehicle |
| F18 | Sample source:mouse primary astrocytes | Genotype:Ent7 knockout | treatment:Vehicle |
| F19 | Sample source:mouse primary astrocytes | Genotype:Ent8 knockout | treatment:TNF𝝰/IL-1𝝰 |
| F20 | Sample source:mouse primary astrocytes | Genotype:Ent9 knockout | treatment:TNF𝝰/IL-1𝝰 |
| F21 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNF𝝰/IL-1𝝰 |
| F22 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNF𝝰/IL-1𝝰/Forodesine |
| F23 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNF𝝰/IL-2𝝰/Forodesine |
| F24 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNF𝝰/IL-3𝝰/Forodesine |
| F25 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNF𝝰/IL-4𝝰/Forodesine |
| F26 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNF𝝰/IL-5𝝰/Forodesine |
| F27 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNF𝝰/IL-6𝝰/Forodesine |
| F28 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:TNF𝝰/IL-7𝝰/Forodesine |
| F29 | Sample source:mouse primary astrocytes | Genotype:Wild-type | treatment:Vehicle |