Clustering data with hclust algorithm for (Study ST004223)
(Analysis AN007026)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|---|
| LPE 22:4 | ME1140755 | 0.61 | 0.72 | 0.56 | 0.62 | 1.12 | 1.31 | 0.92 | 1.07 |
| PC 18:0/18:1 | ME1140712 | 0.59 | 0.74 | 0.55 | 0.75 | 1.03 | 1.20 | 0.98 | 1.19 |
| PC 18:0/18:2, 18:1/18:1 | ME1140711 | 0.60 | 0.73 | 0.56 | 0.69 | 1.00 | 1.20 | 1.03 | 1.19 |
| LPC 18:1 | ME1140736 | 0.52 | 0.47 | 0.57 | 0.62 | 1.08 | 1.20 | 1.15 | 1.09 |
| LPC 18:0 | ME1140737 | 0.63 | 0.65 | 0.65 | 0.62 | 1.03 | 1.15 | 1.14 | 1.08 |
| LPE 16:0 | ME1140743 | 0.63 | 0.53 | 0.65 | 0.57 | 1.08 | 1.03 | 1.23 | 1.11 |
| LPE 20:3 | ME1140750 | 0.50 | 0.63 | 0.53 | 0.51 | 1.24 | 1.20 | 1.05 | 1.01 |
| PC P-16:0/18:0, P-18:0/16:0, O-18:1/16:0, O-16:0/18:1 | ME1140701 | 0.55 | 0.54 | 0.42 | 0.49 | 1.14 | 1.17 | 1.05 | 1.19 |
| PC 18:0/22:4, 20:0/20:4, 20:2/20:2 | ME1140726 | 1.17 | 1.29 | 0.95 | 1.13 | 0.88 | 1.09 | 0.89 | 0.99 |
| PC O-16:0/18:0 | ME1140702 | 1.10 | 1.08 | 1.12 | 0.87 | 1.04 | 0.94 | 0.96 | 0.99 |
| SM 18:1;O2/18:0 | ME1140686 | 1.15 | 1.09 | 1.02 | 0.99 | 1.02 | 0.96 | 0.98 | 0.95 |
| PC 16:0/18:1 | ME1140704 | 0.80 | 0.86 | 0.79 | 0.84 | 1.04 | 1.08 | 1.01 | 1.07 |
| PC 18:0/22:5 | ME1140725 | 0.89 | 0.96 | 0.74 | 0.88 | 0.93 | 1.13 | 0.95 | 1.15 |
| PC P-18:1/20:1, P-16:1/22:1 | ME1140714 | 0.93 | 0.96 | 0.83 | 0.78 | 0.97 | 1.14 | 0.89 | 1.15 |
| PC 16:1/16:0, 14:1/18:0 | ME1140699 | 0.96 | 0.96 | 0.85 | 0.82 | 1.08 | 0.93 | 1.11 | 0.97 |
| PC 16:0/18:2 | ME1140703 | 0.88 | 0.83 | 0.84 | 0.78 | 0.98 | 1.01 | 1.19 | 0.99 |
| PC 16:0/22:6, 18:2/20:4 | ME1140716 | 0.87 | 0.84 | 0.89 | 0.89 | 1.04 | 1.00 | 1.11 | 0.99 |
| PC 18:1/18:2, 16:0/20:3 | ME1140710 | 1.04 | 0.98 | 0.91 | 0.94 | 0.94 | 0.99 | 1.13 | 0.96 |
| PC 18:0/20:3 | ME1140719 | 0.92 | 1.01 | 0.92 | 0.83 | 0.95 | 1.13 | 0.98 | 1.03 |
| LPE 20:4 | ME1140749 | 0.91 | 0.95 | 0.89 | 0.88 | 1.09 | 1.08 | 0.96 | 0.98 |
| PC 18:0/22:6 | ME1140724 | 0.93 | 0.99 | 0.92 | 1.01 | 1.02 | 1.02 | 1.00 | 1.01 |
| PC 18:1/22:6, 18:2/22:5 | ME1140723 | 0.92 | 0.95 | 0.91 | 0.97 | 1.01 | 1.02 | 1.05 | 0.99 |
| LPC 16:0 | ME1140735 | 0.78 | 0.71 | 0.88 | 0.75 | 1.05 | 1.05 | 1.18 | 0.96 |
| LPE 18:0 | ME1140748 | 0.81 | 0.66 | 0.87 | 0.69 | 0.99 | 0.91 | 1.27 | 1.08 |
| LPC 22:6 | ME1140740 | 0.81 | 0.66 | 1.07 | 0.93 | 1.04 | 1.06 | 1.16 | 0.90 |
| LPE 16:1 | ME1140742 | 0.88 | 0.67 | 0.94 | 0.98 | 1.07 | 0.84 | 1.18 | 1.05 |
| LPE P-18:0 | ME1140745 | NA | NA | NA | NA | 0.96 | 0.82 | 1.19 | 1.01 |
| PC 18:2/22:6 | ME1140722 | NA | NA | NA | NA | 0.82 | 0.89 | 1.34 | 0.92 |
| LPC 20:1 | ME1140739 | NA | NA | NA | NA | 0.84 | 1.20 | 0.89 | 1.10 |
| PC 18:0/22:2, 20:0/20:2 | ME1140727 | NA | NA | NA | NA | 0.81 | 1.19 | 0.82 | 1.24 |
| SM 18:1;O2/20:1 | ME1140687 | NA | NA | NA | NA | 1.08 | 1.04 | 0.73 | 1.15 |
| SM 18:1;O2/23:1 | ME1140692 | NA | NA | NA | NA | 1.06 | 0.99 | 0.99 | 0.96 |
| SM 18:1;O2/21:0 | ME1140689 | NA | NA | NA | NA | 1.04 | 0.96 | 1.10 | 0.89 |
| PC 22:6/22:6 | ME1140733 | NA | NA | NA | NA | 1.11 | 0.96 | 1.03 | 0.88 |
| LPE 18:2 | ME1140746 | NA | NA | NA | NA | 1.09 | 0.99 | 1.04 | 0.85 |
| PC P-21:1/22:6 | ME1140729 | NA | NA | NA | NA | 1.07 | 1.01 | 1.03 | 0.88 |
| SM 18:1;O2/24:2 | ME1140694 | NA | NA | NA | NA | 1.02 | 1.15 | 0.94 | 0.89 |
| LPE 20:2 | ME1140751 | NA | NA | NA | NA | 1.08 | 1.10 | 0.84 | 0.98 |
| LPE 22:5 | ME1140754 | NA | NA | NA | NA | 1.10 | 1.12 | 0.88 | 0.90 |
| SM 18:1;O2/21:1 | ME1140690 | NA | NA | NA | NA | 0.97 | 0.99 | 1.00 | 1.05 |
| PC P-18:0/18:1, P-18:1/18:0 | ME1140706 | NA | NA | NA | NA | 0.92 | 1.05 | 0.89 | 1.16 |
| PC 20:0/22:1 | ME1140732 | NA | NA | NA | NA | 1.00 | 1.10 | 0.89 | 1.03 |
| PC P-20:1/22:6 | ME1140728 | NA | NA | NA | NA | 0.97 | 1.10 | 0.88 | 1.07 |
| PC 20:0/22:2, 20:2/22:0 | ME1140731 | NA | NA | NA | NA | 0.91 | 1.12 | 0.91 | 1.08 |
| PC 18:0/18:0 | ME1140713 | NA | NA | NA | NA | 0.96 | 1.03 | 0.94 | 1.09 |
| PC P-21:1/22:5 | ME1140730 | NA | NA | NA | NA | 0.93 | 1.07 | 0.94 | 1.09 |
| LPE P-16:0 | ME1140741 | 0.39 | 0.29 | 0.36 | 0.34 | 1.14 | 0.96 | 1.41 | 1.21 |
| PC 18:0/20:1, P-18:1/22:6 | ME1140721 | 0.13 | 0.20 | 0.10 | 0.22 | 1.07 | 1.39 | 1.03 | 1.49 |
| PC 18:0/20:2, P-18:2/22:6 | ME1140720 | 0.22 | 0.39 | 0.23 | 0.38 | 1.00 | 1.38 | 1.01 | 1.44 |
| HexCer 18:1;O2/24:1 | ME1140677 | 0.17 | 0.25 | 0.16 | 0.26 | 1.10 | 1.39 | 1.19 | 1.22 |
| LPE 20:1 | ME1140752 | 0.14 | 0.27 | 0.14 | 0.23 | 1.13 | 1.43 | 1.12 | 1.23 |
| HexCer 18:1;O2/22:1 | ME1140670 | 0.20 | 0.30 | 0.17 | 0.35 | 1.05 | 1.39 | 1.16 | 1.26 |
| HexCer 18:1;O2/21:0;O | ME1140672 | 0.20 | 0.33 | 0.16 | 0.29 | 1.11 | 1.32 | 1.17 | 1.27 |
| HexCer 18:1;O2/24:0;O | ME1140682 | 0.22 | 0.31 | 0.23 | 0.27 | 1.08 | 1.36 | 1.15 | 1.25 |
| HexCer 18:1;O2/24:2 | ME1140676 | 0.23 | 0.36 | 0.23 | 0.42 | 1.06 | 1.42 | 1.21 | 1.09 |
| HexCer 18:1;O2/23:0, 18:1;O2/22:1;O | ME1140674 | 0.25 | 0.35 | 0.24 | 0.34 | 1.15 | 1.27 | 1.26 | 1.10 |
| LPE 18:1 | ME1140747 | 0.23 | 0.31 | 0.25 | 0.31 | 1.25 | 1.28 | 1.16 | 1.11 |
| PC O-18:0/18:1, P-18:0/18:0 | ME1140707 | 0.34 | 0.36 | 0.27 | 0.28 | 1.17 | 1.23 | 1.09 | 1.28 |
| HexCer 18:1;O2/18:0;O | ME1140667 | 0.34 | 0.43 | 0.30 | 0.36 | 1.22 | 1.23 | 1.09 | 1.17 |
| SM 18:1;O2/20:0 | ME1140688 | 0.36 | 0.38 | 0.39 | 0.37 | 1.24 | 1.18 | 1.09 | 1.20 |
| HexCer 18:1;O2/22:0;O | ME1140675 | 0.28 | 0.45 | 0.28 | 0.37 | 1.03 | 1.32 | 1.12 | 1.29 |
| HexCer 18:1;O2/23:0;O | ME1140679 | 0.35 | 0.50 | 0.34 | 0.43 | 1.10 | 1.24 | 1.16 | 1.17 |
| HexCer 18:1;O2/22:2;O | ME1140673 | 0.31 | 0.48 | 0.26 | 0.49 | 1.09 | 1.31 | 1.17 | 1.12 |
| HexCer 18:1;O2/25:1, 18:1;O2/24:2;O | ME1140680 | 0.33 | 0.51 | 0.35 | 0.55 | 1.04 | 1.29 | 1.15 | 1.17 |
| PC P-18:0/20:0, P-16:0/22:0 | ME1140715 | 0.42 | 0.48 | 0.39 | 0.39 | 1.05 | 1.26 | 1.10 | 1.25 |
| HexCer 18:1;O2/20:0;O | ME1140669 | 0.35 | 0.57 | 0.34 | 0.46 | 1.04 | 1.30 | 1.07 | 1.25 |
| HexCer 18:1;O2/24:1;O, 18:1;O2/25:0 | ME1140681 | 0.32 | 0.55 | 0.37 | 0.52 | 0.98 | 1.32 | 1.10 | 1.26 |
| SM 18:1;O2/16:0 | ME1140684 | 0.30 | 0.28 | 0.24 | 0.22 | 1.42 | 1.26 | 1.06 | 1.07 |
| HexCer 18:1;O2/20:0 | ME1140668 | 0.10 | 0.14 | 0.09 | 0.12 | 1.20 | 1.40 | 1.17 | 1.23 |
| HexCer 18:1;O2/22:0 | ME1140671 | 0.12 | 0.16 | 0.10 | 0.15 | 1.15 | 1.40 | 1.21 | 1.22 |
| HexCer 18:1;O2/24:0 | ME1140678 | 0.10 | 0.14 | 0.10 | 0.14 | 1.16 | 1.41 | 1.23 | 1.19 |
| SM 18:1;O2/24:1 | ME1140695 | 0.09 | 0.11 | 0.09 | 0.13 | 1.21 | 1.28 | 1.27 | 1.24 |
| SM 18:1;O2/22:0 | ME1140691 | 0.07 | 0.07 | 0.06 | 0.08 | 1.27 | 1.28 | 1.24 | 1.26 |
| SM 18:1;O2/24:0 | ME1140696 | 0.04 | 0.05 | 0.05 | 0.05 | 1.28 | 1.31 | 1.27 | 1.21 |
| LPE P-18:1 | ME1140744 | 0.19 | 0.18 | 0.19 | 0.25 | 1.20 | 1.10 | 1.33 | 1.25 |
| HexCer 18:1;O2/18:0 | ME1140666 | 0.14 | 0.16 | 0.11 | 0.13 | 1.32 | 1.25 | 1.27 | 1.10 |
| SM 18:1;O2/23:0 | ME1140693 | 0.16 | 0.15 | 0.15 | 0.12 | 1.36 | 1.14 | 1.28 | 1.15 |
| LPC 14:1 | ME1140734 | 0.93 | 0.80 | 1.08 | 1.27 | NA | NA | NA | NA |
| LPC 20:4 | ME1140738 | 1.07 | 0.86 | 1.12 | 0.98 | NA | NA | NA | NA |
| HexCer 18:1;O2/25:1;O, 18:1;O2/26:0 | ME1140683 | 0.67 | 1.16 | 0.85 | 1.39 | NA | NA | NA | NA |
| PC O-16:0/20:0 | ME1140708 | 1.03 | 1.19 | 0.80 | 0.88 | NA | NA | NA | NA |
| CAR 16:0 | ME1140758 | 0.80 | 1.40 | 0.70 | 1.03 | NA | NA | NA | NA |
| CAR 18:1 | ME1140759 | 0.73 | 1.47 | 0.73 | 1.03 | NA | NA | NA | NA |
| PC 14:0/16:0 | ME1140698 | 1.30 | 1.50 | 1.18 | 1.32 | 0.98 | 0.90 | 0.81 | 0.93 |
| PC 18:1/20:4, 16:0/22:5 | ME1140717 | 1.45 | 1.44 | 1.22 | 1.29 | 0.85 | 0.92 | 0.93 | 0.89 |
| PC P-14:0/16:0 | ME1140697 | 1.81 | 1.88 | 1.52 | 1.90 | 0.82 | 0.75 | 0.71 | 0.83 |
| SM 18:1;O2/18:1 | ME1140685 | 1.92 | 1.79 | 1.38 | 1.71 | 0.86 | 0.82 | 0.69 | 0.82 |
| PC 18:2/18:2, 16:0/20:4 | ME1140709 | 1.90 | 1.76 | 1.58 | 1.56 | 0.80 | 0.77 | 0.86 | 0.75 |
| PC 18:2/20:2, 18:0/20:4 | ME1140718 | 1.88 | 1.84 | 1.50 | 1.59 | 0.80 | 0.82 | 0.77 | 0.80 |
| PC 16:0/16:0 | ME1140700 | 1.67 | 1.74 | 1.77 | 1.58 | 0.83 | 0.79 | 0.75 | 0.88 |
| LPE 22:6 | ME1140753 | 1.53 | 1.44 | 1.71 | 1.37 | 0.93 | 0.88 | 0.82 | 0.80 |
| PC 16:0/18:0 | ME1140705 | 1.49 | 1.68 | 1.54 | 1.36 | 0.85 | 0.85 | 0.80 | 0.93 |
Factors:
| F1 | Sample source:mouse cerebrum | genotype:Cre+ |
| F2 | Sample source:mouse cerebrum | genotype:Cre- |
| F3 | Sample source:mouse cerebrum | genotype:Trem2 KO/Cre+ |
| F4 | Sample source:mouse cerebrum | genotype:Trem2 KO/Cre- |
| F5 | Sample source:mouse spinal cord | genotype:Cre+ |
| F6 | Sample source:mouse spinal cord | genotype:Cre- |
| F7 | Sample source:mouse spinal cord | genotype:Trem2 KO/Cre+ |
| F8 | Sample source:mouse spinal cord | genotype:Trem2 KO/Cre- |
