Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST004240)

(Analysis AN007057)

Metabolite	Structure	F1	F2	F3	F4	F5
1-methylnicotinamide	ME1147962	0.10	0.19	0.19	0.15	3.51
C20:4 carnitine	ME1148012	0.13	0.21	0.18	0.11	3.53
C16 carnitine	ME1148007	0.34	0.46	0.50	0.43	3.28
C14 carnitine	ME1148004	0.37	0.50	0.52	0.42	3.20
C2 carnitine	ME1147990	0.31	0.51	0.57	0.41	3.20
carnitine	ME1147989	0.26	0.39	0.43	0.29	3.62
creatine	ME1148022	0.27	0.47	0.49	0.40	3.38
sarcosine	ME1148068	0.25	0.44	0.46	0.38	3.47
C18:1 carnitine	ME1148009	0.32	0.41	0.44	0.35	3.48
C4 carnitine	ME1147993	0.29	0.43	0.47	0.35	3.47
creatinine	ME1148023	0.02	0.02	0.03	0.02	4.91
C3 carnitine	ME1147991	0.16	0.31	0.33	0.23	3.97
trimethylamine-N-oxide	ME1148080	0.11	0.07	0.07	0.07	4.06
citrulline	ME1148017	0.11	0.22	0.22	0.19	4.27
C18:2 carnitine	ME1148010	0.08	0.10	0.11	0.09	4.46
taurine	ME1148072	0.09	0.14	0.15	0.13	4.48
C10 carnitine	ME1148000	0.23	0.25	0.28	NA	1.37
C14:1 carnitine	ME1148005	0.30	0.37	0.38	0.34	2.30
C26 carnitine	ME1148013	0.30	0.51	0.35	0.31	2.25
beta-alanine	ME1147986	0.40	0.38	0.44	0.40	1.88
C12 carnitine	ME1148002	0.35	0.31	0.34	0.30	1.78
C4-OH carnitine	ME1147994	0.57	0.84	0.94	0.66	1.99
alanine	ME1147974	0.66	0.80	0.79	0.75	2.00
glycine	ME1148036	0.63	0.78	0.76	0.75	2.10
isoleucine	ME1148040	0.46	0.79	0.81	0.79	2.16
tryptophan	ME1148081	0.54	0.74	0.78	0.74	2.20
acetylcholine	ME1147971	0.73	0.79	0.84	0.85	1.79
dimethylglycine	ME1148025	0.83	0.75	0.75	0.72	1.96
C5 carnitine	ME1147995	0.35	0.62	0.70	0.49	2.84
C5:1 carnitine	ME1147996	0.41	0.66	0.61	0.45	2.56
C20 carnitine	ME1148011	0.54	0.71	0.73	0.52	2.50
methionine	ME1148044	0.51	0.66	0.70	0.67	2.46
betaine	ME1147987	0.50	0.67	0.70	0.61	2.52
C3-DC-CH3 carnitine	ME1147992	0.51	0.69	0.73	0.61	2.46
1-methylhistamine	ME1147961	1.48	0.88	NA	NA	0.94
proline[13]C1[15]N1	ME1148063	0.18	1.52	1.35	2.06	0.38
pipecolic acid[15]N	ME1148058	0.32	1.24	1.26	1.10	0.12
pipecolic acid	ME1148057	0.35	1.60	1.58	1.44	0.03
proline	ME1148061	0.07	1.59	1.59	1.51	0.25
proline[15]N	ME1148062	0.06	1.59	1.59	1.53	0.24
xanthosine	ME1148084	1.13	0.62	1.37	0.94	NA
histamine	ME1148037	1.34	0.95	1.04	0.97	0.64
SDMA	ME1148069	1.40	1.03	1.09	0.98	0.50
histidine	ME1148038	1.18	1.07	1.15	1.14	0.45
methylthioadenosine	ME1148046	1.06	1.17	1.09	1.29	0.39
GABA	ME1148026	1.67	0.98	0.99	0.85	0.01
glutamate	ME1148028	1.70	1.12	1.11	1.01	0.06
s-adenosylmethionine	ME1148067	1.48	1.27	0.94	1.13	0.18
aspartate	ME1147985	1.28	1.24	1.18	1.11	0.19
spermidine	ME1148071	1.25	1.16	1.19	1.15	0.25
adenosine	ME1147972	1.28	1.13	1.31	1.04	0.23
lysine	ME1148043	1.33	1.26	1.22	0.99	0.21
putrescine	ME1148065	1.30	1.25	1.27	1.16	0.02
phosphocholine	ME1148055	1.51	1.15	1.17	1.16	0.01
NMMA	ME1148049	1.42	1.25	1.25	0.99	0.09
cytosine	ME1148024	1.49	1.24	1.22	1.03	0.01
thiamine	ME1148073	1.42	1.24	1.25	1.08	0.01
arginine[13]C1[15]N1	ME1147981	1.44	1.06	1.04	0.86	0.18
ADMA	ME1147973	1.48	1.17	1.16	1.06	0.13
arginine	ME1147979	1.51	1.14	1.12	1.01	0.21
arginine[15]N	ME1147980	1.50	1.14	1.16	1.01	0.20
carnosine	ME1148015	0.90	1.28	1.11	1.19	0.03
glutamate[15]N	ME1148029	1.42	0.79	0.82	0.76	NA
glutamate[13]C5	ME1148031	1.12	0.95	0.94	1.00	NA
cAMP	ME1148014	1.24	1.02	0.89	0.82	NA
phosphoethanolamine	ME1148056	1.19	1.07	0.94	0.80	NA
5-adenosylhomocysteine	ME1147968	0.99	1.10	0.99	0.92	NA
2-deoxycytidine	ME1147967	1.11	1.05	1.03	0.81	NA
homocysteine	ME1148039	1.04	1.03	1.08	0.81	NA
cotinine	ME1148021	0.72	0.65	1.45	1.36	0.82
C6 carnitine	ME1147997	0.82	0.90	1.37	0.67	1.31
ornithine	ME1148050	0.81	0.89	0.95	0.79	1.56
valine	ME1148083	0.75	1.01	0.99	0.98	1.27
C18 carnitine	ME1148008	0.78	0.93	1.01	0.84	1.44
phenylalanine	ME1148054	0.77	0.97	0.96	0.91	1.38
5-hydroxytryptophan	ME1147970	0.48	0.93	0.81	0.89	1.60
methionine sulfoxide	ME1148045	0.62	0.97	1.00	0.97	1.44
glutamine	ME1148032	0.61	0.95	1.03	0.94	1.47
pyroglutamic acid	ME1148066	0.57	0.95	1.04	0.94	1.49
glutamine[15]N	ME1148033	0.58	0.94	0.98	0.87	1.64
tyrosine	ME1148082	0.65	0.92	0.94	0.86	1.63
niacinamide	ME1148048	0.85	1.29	1.46	0.94	0.46
leucine	ME1148042	0.58	1.12	1.09	1.06	1.15
serine	ME1148070	0.83	1.07	1.03	0.97	1.10
threonine	ME1148074	0.77	1.09	1.07	1.03	1.05
alpha-glycerophosphocholine	ME1147976	1.11	1.13	1.09	0.95	0.72
choline	ME1148016	1.17	0.93	1.09	1.04	0.77
phenylalanine-d8	ME1147958	1.01	1.01	1.04	1.03	0.91
valine-d8	ME1147959	1.00	1.00	1.03	1.02	0.95
glutamate[13]C3[15]N1	ME1148030	0.98	1.20	1.03	0.95	0.87
trans-hydroxyproline[13]C1[15]N1	ME1148078	0.88	1.19	1.02	1.09	0.87
anthranilic acid	ME1147978	0.79	1.15	1.14	1.04	0.85
asparagine	ME1147984	0.91	1.12	1.12	1.06	0.79
trans-hydroxyproline[15]N	ME1148077	0.91	1.12	1.12	1.06	0.79

Factors:

F1	Sample source:infected RBC (iRBC) \| Parasite_type:PF Dd2 iRBC \| Parasite_line:Dd2
F2	Sample source:infected RBC (iRBC) \| Parasite_type:PF MFR-4 KO iRBC Clone 1 \| Parasite_line:Dd2ΔApiAT2 Clone 1
F3	Sample source:infected RBC (iRBC) \| Parasite_type:PF MFR-4 KO iRBC Clone 2 \| Parasite_line:Dd2ΔApiAT2 Clone 2
F4	Sample source:infected RBC (iRBC) \| Parasite_type:PF MFR-4 KO iRBC Clone 3 \| Parasite_line:Dd2ΔApiAT2 Clone 3
F5	Sample source:uninfected RBC (uRBC) \| Parasite_type:uRBC \| Parasite_line:Control RBCs

Data matrix