Clustering data with hclust algorithm for (Study ST004385)
(Analysis AN007326)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 |
|---|---|---|---|---|---|---|---|---|---|---|
| LacCer(d18:1/16:0) | ME1215385 | 1.00 | 0.92 | 0.79 | 0.88 | 1.12 | 1.72 | 0.88 | 0.82 | 0.78 |
| LPC(26:0) | ME1215400 | 0.99 | 0.80 | 0.60 | 0.75 | 1.25 | 1.81 | 0.99 | 0.85 | 0.94 |
| LPC(26:1) | ME1215401 | 1.00 | 0.86 | 0.69 | 0.74 | 1.32 | 1.66 | 0.94 | 0.91 | 0.83 |
| LPC(24:0) | ME1215398 | 0.93 | 0.86 | 0.71 | 0.77 | 1.21 | 1.72 | 0.98 | 0.94 | 0.79 |
| LPC(24:1) | ME1215399 | 0.99 | 0.83 | 0.68 | 0.74 | 1.20 | 1.70 | 1.03 | 0.96 | 0.78 |
| CE(18:1(d7)) | ME1215343 | 1.12 | 1.06 | 0.99 | 1.04 | 1.12 | 0.90 | 1.12 | 1.12 | 0.20 |
| TG(20:4_36:0) | ME1215465 | 0.99 | 1.14 | 1.14 | 1.10 | 1.02 | 0.95 | 1.08 | 1.09 | 0.14 |
| TG(20:4_36:2) | ME1215466 | 1.26 | 1.10 | 1.23 | 1.09 | 0.91 | 0.83 | 0.98 | 1.07 | 0.23 |
| TG(20:4_34:2) | ME1215463 | 1.18 | 1.04 | 1.12 | 1.05 | 1.02 | 1.11 | 0.93 | 0.95 | 0.34 |
| TG(20:4_36:3) | ME1215467 | 1.22 | 1.07 | 1.16 | 0.99 | 1.01 | 0.99 | 0.94 | 1.02 | 0.31 |
| TG(22:6_38:1) | ME1215469 | 0.92 | 0.95 | 0.85 | 0.90 | 1.30 | 1.33 | 1.25 | 0.99 | 0.18 |
| TG(20:4_32:1) | ME1215462 | 1.07 | 1.00 | 1.06 | 0.99 | 0.91 | 1.47 | 0.97 | 0.93 | 0.34 |
| TG(20:4_34:3) | ME1215464 | 1.07 | 0.96 | 1.14 | 0.99 | 0.93 | 1.39 | 0.90 | 0.95 | 0.43 |
| TG(15:0/18:1(d7)/15:0) | ME1215458 | 1.00 | 1.01 | 1.02 | 0.97 | 0.95 | 1.45 | 1.06 | 1.03 | 0.20 |
| TG(18:0_36:2) | ME1215459 | 1.12 | 1.05 | 0.95 | 0.95 | 1.02 | 1.29 | 1.12 | 1.03 | 0.13 |
| TG(22:6_36:2) | ME1215468 | 0.99 | 1.03 | 0.95 | 0.99 | 1.00 | 1.32 | 1.09 | 1.10 | 0.24 |
| TG(22:6_38:2) | ME1215470 | 1.01 | 0.99 | 0.94 | 0.91 | 1.10 | 1.31 | 1.13 | 1.08 | 0.20 |
| TG(18:1_34:2) | ME1215460 | 1.09 | 0.99 | 0.91 | 0.88 | 0.77 | 1.83 | 0.93 | 1.04 | 0.25 |
| TG(18:1_34:3) | ME1215461 | 1.23 | 0.97 | 1.01 | 0.83 | 0.58 | 1.31 | 1.05 | 1.41 | 0.34 |
| 7-keto-Cholesterol | ME1215336 | 1.16 | 1.03 | 1.26 | 1.13 | 0.76 | 0.55 | 1.02 | 1.01 | 1.13 |
| MG(20:4) | ME1215410 | 0.94 | 0.81 | 1.38 | 1.04 | 0.82 | 0.92 | 1.28 | 0.93 | 0.81 |
| LPC(16:1) | ME1215392 | 1.20 | 0.93 | 1.08 | 1.12 | 0.82 | 0.78 | 1.20 | 1.11 | 0.60 |
| LPC(20:4) | ME1215396 | 1.19 | 0.98 | 1.16 | 1.14 | 0.81 | 0.69 | 1.13 | 1.12 | 0.65 |
| PC(O-16:0/0:0) | ME1215428 | 1.14 | 0.87 | 0.94 | 1.11 | 1.01 | 0.91 | 1.11 | 1.12 | 0.64 |
| LPC(22:6) | ME1215397 | 1.16 | 0.93 | 1.03 | 1.11 | 0.93 | 0.81 | 1.17 | 1.08 | 0.65 |
| LPC(18:1) | ME1215395 | 1.11 | 0.98 | 1.03 | 1.08 | 0.94 | 0.85 | 1.11 | 1.06 | 0.72 |
| PC(O-16:0/2:0) | ME1215429 | 1.14 | 0.98 | 1.04 | 1.09 | 0.93 | 0.82 | 1.13 | 1.07 | 0.68 |
| Coenzyme Q10 | ME1215361 | 0.97 | 1.00 | 1.03 | 1.10 | 1.12 | 0.93 | 1.10 | 1.04 | 0.52 |
| GB3(d18:1/18:0(d3)) | ME1215371 | 1.04 | 1.06 | 1.05 | 1.05 | 1.03 | 1.13 | 0.94 | 0.94 | 0.60 |
| N-Oleoylethanolamine | ME1215411 | 1.19 | 1.00 | 0.99 | 1.09 | 0.99 | 0.79 | 1.01 | 0.95 | 1.01 |
| MG(18:1) | ME1215409 | 1.05 | 1.14 | 0.77 | 1.03 | 1.05 | 1.10 | 0.92 | 1.05 | 0.83 |
| MG(16:0) | ME1215405 | 1.09 | 1.03 | 0.83 | 1.00 | 1.10 | 1.05 | 0.85 | 1.01 | 1.06 |
| MG(18:0) | ME1215407 | 1.06 | 1.03 | 0.84 | 1.01 | 1.08 | 1.10 | 0.91 | 1.01 | 0.94 |
| DG(18:0_20:4) | ME1215366 | 0.95 | 0.86 | 1.13 | 0.97 | 0.94 | 1.09 | 1.13 | 0.97 | 0.91 |
| 4-beta-Hydroxycholesterol | ME1215335 | 1.05 | 1.06 | 1.02 | 1.05 | 0.83 | 0.90 | 1.05 | 1.07 | 0.94 |
| PE(40:4) | ME1215441 | 0.99 | 1.03 | 1.12 | 1.04 | 0.91 | 0.89 | 1.03 | 1.04 | 0.88 |
| Sphinganine | ME1215451 | 1.06 | 1.08 | 1.07 | 1.08 | 0.95 | 0.81 | 1.04 | 1.01 | 0.86 |
| Sphingosine | ME1215453 | 1.00 | 1.10 | 1.02 | 0.98 | 1.03 | 1.03 | 0.96 | 1.00 | 0.81 |
| Glucosylsphingosine(d5) | ME1215378 | 1.02 | 0.99 | 1.03 | 1.07 | 0.93 | 1.10 | 1.03 | 0.99 | 0.73 |
| Sphingosine(d17:1) | ME1215457 | 1.02 | 0.96 | 1.05 | 1.00 | 0.97 | 1.02 | 1.08 | 1.00 | 0.83 |
| PC(O-18:0/2:0) | ME1215430 | 1.11 | 1.03 | 1.00 | 1.02 | 0.96 | 0.96 | 1.03 | 1.05 | 0.73 |
| LPC(16:0) | ME1215391 | 1.06 | 0.99 | 1.03 | 1.04 | 0.96 | 0.95 | 1.06 | 1.03 | 0.83 |
| LPC(18:0) | ME1215393 | 1.07 | 1.03 | 1.00 | 1.01 | 0.98 | 0.98 | 1.01 | 1.03 | 0.80 |
| HexCer(d18:1/24:1) | ME1215383 | 0.97 | 0.99 | 0.92 | 0.94 | 1.11 | 1.14 | 1.10 | 0.98 | 0.78 |
| DG(18:0_18:1) | ME1215365 | 1.02 | 1.01 | 0.87 | 0.98 | 1.11 | 1.05 | 1.13 | 0.93 | 0.83 |
| Sphinganine 1-phosphate | ME1215452 | 1.02 | 0.97 | 0.95 | 0.96 | 1.09 | 1.05 | 1.08 | 0.95 | 0.90 |
| DG(18:0_22:6) | ME1215367 | 1.00 | 0.85 | 0.95 | 0.96 | 1.07 | 1.15 | 1.12 | 0.93 | 0.96 |
| Sitosteryl hexoside | ME1215445 | 0.97 | 0.85 | 0.98 | 1.01 | 0.99 | 1.19 | 1.01 | 1.05 | 0.92 |
| Cer(d18:1/16:0(d7)) | ME1215353 | 0.98 | 0.98 | 0.93 | 0.95 | 1.01 | 1.17 | 1.04 | 0.97 | 0.95 |
| GlcCer(d18:1(d5)/18:0) | ME1215375 | 0.98 | 0.97 | 0.99 | 1.02 | 1.01 | 1.14 | 1.01 | 0.95 | 0.88 |
| PE(15:0/18:1(d7)) | ME1215431 | 1.00 | 0.99 | 0.98 | 0.99 | 1.00 | 1.10 | 1.03 | 1.00 | 0.87 |
| DG(18:1/18:1) | ME1215368 | 1.05 | 0.99 | 0.91 | 0.98 | 1.09 | 1.01 | 0.99 | 0.91 | 1.10 |
| Palmitoylethanolamine | ME1215413 | 1.16 | 0.93 | 0.90 | 0.96 | 1.12 | 1.00 | 1.01 | 0.89 | 1.05 |
| DG(18:1_20:4) | ME1215369 | 0.99 | 0.87 | 1.07 | 1.01 | 1.00 | 1.00 | 1.06 | 0.95 | 1.06 |
| Cholesterol | ME1215358 | 1.02 | 0.95 | 0.92 | 0.99 | 1.00 | 1.13 | 0.96 | 1.01 | 1.03 |
| DG(15:0/18:1(d7)) | ME1215362 | 0.97 | 1.00 | 0.98 | 0.97 | 1.02 | 1.08 | 0.96 | 0.95 | 1.10 |
| Cer(d18:1/18:0) | ME1215355 | 0.99 | 1.01 | 1.09 | 1.01 | 0.96 | 0.99 | 0.92 | 1.06 | 0.95 |
| MG(18:1(d7)) | ME1215408 | 1.02 | 1.06 | 1.00 | 0.98 | 1.04 | 0.97 | 1.03 | 0.94 | 0.93 |
| PE(36:1) | ME1215435 | 0.99 | 1.02 | 0.99 | 1.01 | 1.03 | 0.99 | 1.05 | 0.99 | 0.86 |
| 24-Hydroxycholesterol | ME1215332 | 1.01 | 1.04 | 1.06 | 0.99 | 0.98 | 0.88 | 1.00 | 1.03 | 1.00 |
| PC(38:4) | ME1215424 | 1.00 | 1.01 | 1.04 | 1.01 | 0.98 | 0.95 | 0.98 | 1.00 | 1.04 |
| PE(38:4) | ME1215438 | 1.00 | 1.02 | 1.05 | 1.02 | 0.97 | 0.95 | 1.00 | 1.01 | 0.97 |
| SM(d18:1(d9)/18:1) | ME1215446 | 1.02 | 0.98 | 0.95 | 0.98 | 1.05 | 1.06 | 0.99 | 0.98 | 0.97 |
| SM(d18:1/24:1) | ME1215450 | 0.99 | 1.00 | 0.95 | 0.98 | 1.05 | 1.06 | 1.02 | 0.99 | 0.94 |
| PE(34:1) | ME1215434 | 0.98 | 0.99 | 0.97 | 1.00 | 1.01 | 1.06 | 1.03 | 1.00 | 0.93 |
| PE(40:6) | ME1215443 | 0.99 | 0.99 | 0.97 | 1.00 | 1.04 | 1.03 | 1.03 | 0.99 | 0.93 |
| Sphingosine 1-phosphate-d7 | ME1215455 | 1.03 | 0.95 | 1.03 | 0.99 | 1.05 | 0.97 | 1.01 | 0.96 | 1.01 |
| PC(36:2) | ME1215422 | 0.99 | 0.99 | 0.97 | 1.01 | 1.05 | 0.99 | 1.00 | 0.99 | 1.02 |
| PE(40:7) | ME1215444 | 1.00 | 1.00 | 0.95 | 1.01 | 1.04 | 0.98 | 1.01 | 1.00 | 1.00 |
| PE(36:2) | ME1215436 | 1.00 | 0.99 | 0.94 | 1.00 | 1.07 | 0.99 | 1.02 | 1.00 | 0.97 |
| PE(38:6) | ME1215440 | 1.00 | 1.00 | 0.96 | 0.99 | 1.04 | 1.02 | 1.01 | 1.00 | 0.97 |
| PE(36:4) | ME1215437 | 0.99 | 1.02 | 1.03 | 1.01 | 0.99 | 1.01 | 0.97 | 0.99 | 0.98 |
| PC(15:0/18:1(d7)) | ME1215414 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.02 | 0.99 | 0.97 | 1.03 |
| PE(38:5) | ME1215439 | 1.01 | 1.01 | 1.00 | 1.02 | 1.02 | 0.99 | 0.99 | 0.98 | 0.98 |
| PC(36:4) | ME1215423 | 1.00 | 1.01 | 1.01 | 1.00 | 0.99 | 0.98 | 1.00 | 1.00 | 1.02 |
| SM(d18:1/18:0) | ME1215448 | 1.00 | 1.01 | 1.02 | 1.00 | 0.98 | 0.99 | 0.99 | 1.00 | 1.02 |
| PC(40:5) | ME1215426 | 0.99 | 1.01 | 1.00 | 1.00 | 1.02 | 0.97 | 1.02 | 0.99 | 1.01 |
| LPC(18:1(d7)) | ME1215394 | 1.00 | 0.99 | 0.99 | 1.00 | 1.01 | 0.99 | 1.02 | 1.00 | 0.99 |
| PC(38:6) | ME1215425 | 1.00 | 1.00 | 0.99 | 1.00 | 1.01 | 1.01 | 1.00 | 1.00 | 1.00 |
| PC(40:6) | ME1215427 | 1.00 | 1.00 | 0.99 | 1.00 | 1.01 | 1.00 | 1.00 | 0.99 | 1.01 |
| PC(34:1) | ME1215420 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.99 | 1.00 | 1.00 | 1.01 |
| PC(36:1) | ME1215421 | 1.00 | 1.01 | 1.00 | 1.00 | 1.00 | 0.98 | 1.01 | 1.00 | 1.00 |
| LacCer(d18:1/18:0) | ME1215387 | 1.04 | 0.93 | 0.96 | 0.99 | 1.09 | 1.26 | 0.96 | 0.92 | 0.76 |
| Sphingosine 1-phosphate | ME1215454 | 1.03 | 0.95 | 0.82 | 0.86 | 1.22 | 1.31 | 1.01 | 0.86 | 0.90 |
| Cholesteryl hexoside | ME1215360 | 0.99 | 0.97 | 0.88 | 0.93 | 1.10 | 1.26 | 1.00 | 0.98 | 0.84 |
| HexCer(d18:1/16:0) | ME1215379 | 0.97 | 0.95 | 0.87 | 0.89 | 1.19 | 1.36 | 0.96 | 0.89 | 0.86 |
| HexCer(d18:1/18:0) | ME1215380 | 0.96 | 0.99 | 0.89 | 0.89 | 1.13 | 1.34 | 0.99 | 0.92 | 0.82 |
| DG(16:0_20:4) | ME1215364 | 0.94 | 0.85 | 1.01 | 0.93 | 1.03 | 1.31 | 1.05 | 0.89 | 0.99 |
| Cer(d18:1/16:0) | ME1215354 | 0.96 | 0.94 | 0.94 | 0.91 | 1.02 | 1.40 | 0.91 | 0.95 | 0.95 |
| DG(16:0_18:1) | ME1215363 | 1.00 | 1.01 | 0.91 | 0.94 | 1.03 | 1.27 | 0.96 | 0.89 | 0.99 |
| SM(d18:1/16:0) | ME1215447 | 0.99 | 0.98 | 0.95 | 0.93 | 1.02 | 1.26 | 0.92 | 0.97 | 0.96 |
| HexCer(d18:1/24:0) | ME1215382 | 0.97 | 0.93 | 0.84 | 0.88 | 1.15 | 1.39 | 1.14 | 0.99 | 0.50 |
| HexCer(d18:1/22:0) | ME1215381 | 0.96 | 0.96 | 0.90 | 0.89 | 1.15 | 1.34 | 1.09 | 0.95 | 0.60 |
| LacCer(d18:1/24:1) | ME1215389 | 1.00 | 0.98 | 0.93 | 0.93 | 1.10 | 1.31 | 1.04 | 0.93 | 0.65 |
| Cer(d18:1/24:1) | ME1215357 | 0.96 | 0.98 | 0.89 | 0.89 | 1.07 | 1.45 | 0.98 | 0.97 | 0.67 |
| SM(d18:1/24:0) | ME1215449 | 0.93 | 0.97 | 0.94 | 0.95 | 0.99 | 1.35 | 1.05 | 1.01 | 0.68 |
| Cer(d18:1/24:0) | ME1215356 | 0.96 | 0.91 | 1.01 | 0.90 | 1.01 | 1.48 | 0.89 | 1.02 | 0.67 |
| LacCer(d18:1/24:0) | ME1215388 | 1.01 | 0.98 | 0.93 | 0.84 | 1.15 | 1.48 | 0.92 | 1.01 | 0.47 |
| PC(16:0/9:0(CHO)) | ME1215416 | 0.95 | 0.75 | 0.89 | 0.90 | 0.83 | 0.69 | 0.95 | 0.86 | 2.97 |
| PC(16:0/5:0(CHO)) | ME1215415 | 1.02 | 0.82 | 0.97 | 0.95 | 0.94 | 0.77 | 0.92 | 0.89 | 2.18 |
| PC(16:0/9:0(COOH)) | ME1215417 | 1.02 | 0.86 | 0.91 | 0.93 | 0.90 | 0.75 | 1.05 | 0.94 | 2.06 |
| CE(20:5) | ME1215347 | 0.15 | 0.14 | 0.05 | 0.03 | 0.35 | 7.55 | 0.05 | 0.04 | 0.39 |
| CE(16:1) | ME1215342 | 0.27 | 0.30 | 0.12 | 0.09 | 0.58 | 6.85 | 0.12 | 0.11 | 0.28 |
| CE(18:2) | ME1215345 | 0.23 | 0.19 | 0.16 | 0.11 | 0.47 | 7.06 | 0.14 | 0.11 | 0.21 |
| CE(22:6) | ME1215348 | 0.44 | 0.40 | 0.16 | 0.09 | 0.98 | 6.00 | 0.14 | 0.12 | 0.48 |
| CE(18:1) | ME1215344 | 0.59 | 0.58 | 0.35 | 0.30 | 0.98 | 5.00 | 0.36 | 0.34 | 0.17 |
| CE(20:4) | ME1215346 | 0.51 | 0.53 | 0.40 | 0.33 | 0.60 | 5.37 | 0.33 | 0.36 | 0.28 |
Factors:
| F1 | Sample source:Brain | SEX:Female | Genotype:PS19 | Treatment:OIL |
| F2 | Sample source:Brain | SEX:Female | Genotype:PS19 | Treatment:TAMOXIFEN |
| F3 | Sample source:Brain | SEX:Female | Genotype:WT | Treatment:OIL |
| F4 | Sample source:Brain | SEX:Female | Genotype:WT | Treatment:TAMOXIFEN |
| F5 | Sample source:Brain | SEX:Male | Genotype:PS19 | Treatment:OIL |
| F6 | Sample source:Brain | SEX:Male | Genotype:PS19 | Treatment:TAMOXIFEN |
| F7 | Sample source:Brain | SEX:Male | Genotype:WT | Treatment:OIL |
| F8 | Sample source:Brain | SEX:Male | Genotype:WT | Treatment:TAMOXIFEN |
| F9 | Sample source:Brain | SEX:NA | Genotype:NA | Treatment:NA |
