Clustering data with hclust algorithm for (Study ST004401)
(Analysis AN007357)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pyridoxamine | ME1227839 | NA | -54.57 | -49.34 | -42.68 | NA | -51.26 | -85.11 | -74.71 | NA | NA | NA | NA |
| S-Carboxymethyl-cysteine | ME1227847 | 25.29 | 2.24 | 7.83 | 12.54 | 19.50 | 21.96 | NA | NA | NA | NA | NA | 17.29 |
| 4-Acetamidobutanoic acid | ME1227698 | 8.34 | 26.13 | NA | 5.54 | 12.56 | 3.20 | NA | NA | NA | 29.58 | NA | 5.91 |
| Caffeine | ME1227727 | NA | 6.29 | 3.14 | NA | 7.68 | 6.41 | 0.69 | NA | NA | 25.51 | 4.56 | NA |
| Glucosamine 6-sulfate | ME1227761 | NA | -10.42 | -7.27 | NA | -2.50 | -4.14 | -13.36 | -8.66 | NA | -5.21 | NA | NA |
| 3-Hydroxyanthranilic acid | ME1227691 | NA | -3.83 | NA | NA | -3.25 | -4.23 | -1.26 | -5.14 | NA | NA | -9.89 | NA |
| 2-Aminophenol | ME1227683 | 7.39 | 6.34 | 0.68 | 1.16 | 3.92 | NA | NA | 11.14 | NA | NA | 0.83 | NA |
| Lipoamide | ME1227788 | NA | -4.16 | NA | -6.58 | -0.00 | NA | -4.24 | NA | NA | -3.05 | NA | -0.83 |
| N-Acetyl-tryptophan | ME1227810 | 3.36 | NA | NA | NA | 1.45 | NA | 1.43 | 0.99 | NA | 9.22 | NA | 6.14 |
| Purine | ME1227837 | 6.67 | NA | NA | 3.97 | NA | NA | NA | 0.14 | NA | 6.66 | 3.27 | 9.04 |
| Theophylline | ME1227854 | 0.37 | 2.79 | 0.05 | 4.47 | NA | 3.42 | 2.63 | NA | NA | 2.13 | 1.19 | NA |
| Paraxanthine | ME1227831 | 2.87 | 4.32 | NA | 6.93 | NA | 5.29 | 4.07 | NA | NA | NA | 1.84 | NA |
| Theobromine | ME1227853 | 2.87 | 4.32 | NA | 6.93 | NA | 5.29 | 4.07 | NA | NA | NA | 1.84 | NA |
| 5-Methylcytosine | ME1227705 | NA | 3.53 | 0.28 | NA | NA | 2.05 | NA | 0.21 | 6.96 | NA | 3.30 | NA |
| 5-Hydroxylysine | ME1227703 | 0.97 | NA | NA | NA | 4.87 | 0.50 | NA | 5.93 | 0.98 | 0.46 | 1.01 | NA |
| 5-Hydroxy-tryptophan | ME1227704 | 3.11 | 0.24 | 1.41 | 0.33 | NA | 2.21 | 0.01 | 8.39 | NA | NA | 0.38 | NA |
| Diethanolamine | ME1227753 | 2.03 | 2.47 | 2.42 | NA | 2.82 | NA | 3.30 | 2.94 | NA | NA | NA | 3.46 |
| Nicotinic acid | ME1227818 | 1.91 | 5.01 | 1.32 | 0.54 | 3.58 | NA | 4.62 | 7.17 | NA | NA | NA | 5.18 |
| Agmatine | ME1227713 | NA | NA | NA | 0.58 | NA | 0.58 | 1.49 | 0.23 | NA | 2.81 | 2.42 | 7.95 |
| Pyridoxal | ME1227838 | 1.43 | NA | 1.27 | 0.86 | 1.05 | 0.17 | 1.05 | 0.97 | NA | NA | 1.05 | 7.00 |
| alpha-Aminoadipic acid | ME1227716 | NA | 0.66 | NA | 0.33 | 1.09 | NA | 0.92 | 0.65 | 0.68 | 1.05 | 3.29 | 3.52 |
| Cinnamaldehyde | ME1227738 | 1.19 | 1.34 | NA | NA | 1.86 | NA | 1.08 | NA | NA | 1.30 | 6.25 | 3.22 |
| 2-Hydroxypyridine | ME1227685 | 0.86 | 0.01 | 2.11 | NA | NA | 2.11 | 0.79 | 2.61 | NA | 1.90 | 4.13 | NA |
| 4a-Carbinolamine tetrahydrobiopterin | ME1227697 | 1.45 | 1.87 | 3.95 | NA | 0.48 | 0.93 | NA | NA | 0.05 | NA | 3.45 | NA |
| Creatinine | ME1227743 | 0.71 | 0.74 | 0.13 | 3.01 | 3.11 | 2.69 | NA | 0.40 | NA | 1.67 | 0.14 | NA |
| Dethiobiotin | ME1227752 | 0.23 | 0.07 | 0.32 | 1.27 | 1.27 | 0.80 | 1.06 | 1.02 | 3.84 | 0.52 | 1.19 | 0.41 |
| D-Alanine | ME1227751 | NA | NA | NA | NA | NA | NA | 1.95 | 1.87 | 2.15 | 1.87 | 2.08 | 2.12 |
| Homoserine | ME1227775 | NA | NA | NA | NA | NA | NA | 1.00 | 0.93 | 1.07 | 1.02 | 1.00 | 0.98 |
| Glucosaminic acid | ME1227762 | 0.55 | 0.90 | 2.14 | NA | 0.74 | 0.23 | 0.96 | 0.47 | NA | NA | 0.63 | 2.40 |
| N-Methylalanine | ME1227820 | 1.41 | 1.06 | 1.51 | 0.86 | 0.84 | 1.89 | NA | 0.45 | 0.49 | 1.32 | 1.14 | 1.83 |
| 3-Dehydroxycarnitine | ME1227689 | 1.02 | 0.68 | 0.71 | 1.16 | 0.94 | 0.76 | 1.04 | 1.90 | 0.67 | 1.21 | 1.54 | 0.39 |
| 6-Hydroxydopamine | ME1227707 | 1.18 | 0.71 | 0.93 | 1.14 | 1.11 | 0.82 | NA | 1.52 | 1.48 | NA | 1.88 | 1.49 |
| Kynurenine | ME1227784 | 0.30 | 0.34 | 0.56 | 0.77 | 0.66 | 0.75 | 1.58 | 0.71 | 1.37 | 1.09 | 2.20 | 1.66 |
| CAR 2:0 | ME1227730 | 0.96 | 0.78 | 0.77 | 1.19 | 1.15 | 1.08 | 0.95 | 0.80 | 0.75 | 0.82 | 1.43 | 1.31 |
| Cystine | ME1227747 | 1.11 | 0.47 | 1.05 | 1.22 | 1.08 | 0.93 | 0.90 | 1.05 | 1.00 | 1.13 | 0.93 | 1.13 |
| Glutamine | ME1227763 | 0.91 | 0.73 | 0.91 | 1.02 | 1.01 | 1.01 | 1.04 | 1.02 | 1.11 | 0.98 | 1.12 | 1.15 |
| Alanine | ME1227714 | 0.78 | 0.68 | 0.81 | 0.94 | 0.88 | 0.84 | 1.14 | 1.10 | 1.26 | 1.10 | 1.22 | 1.25 |
| Sarcosine | ME1227846 | 0.78 | 0.68 | 0.81 | 0.94 | 0.88 | 0.84 | 1.14 | 1.09 | 1.27 | 1.10 | 1.22 | 1.25 |
| N-Acetyl-mannosamine | ME1227807 | 0.96 | 0.29 | 0.53 | 0.91 | 1.23 | 1.06 | 0.74 | 0.46 | 1.11 | 0.80 | 1.96 | 1.95 |
| Cytidine | ME1227748 | 1.01 | 0.62 | 0.47 | 1.48 | 1.13 | 1.38 | 0.51 | 0.56 | 1.01 | 0.48 | 2.13 | 1.21 |
| Guanine | ME1227769 | 1.08 | 0.68 | 0.99 | 1.46 | 1.21 | 1.28 | 0.69 | 0.64 | 0.93 | NA | 1.41 | 1.64 |
| Hypoxanthine | ME1227779 | 0.93 | 0.64 | 0.98 | 1.58 | 1.10 | 1.15 | 0.65 | 0.57 | 0.79 | 0.62 | 1.36 | 1.62 |
| Thymine | ME1227858 | 1.10 | 0.33 | 1.86 | 2.15 | 0.19 | 1.86 | 0.26 | 0.90 | NA | 0.89 | 0.44 | NA |
| Creatine | ME1227742 | 1.38 | 1.07 | 1.15 | 1.88 | 2.08 | 2.05 | 0.58 | 0.42 | 0.39 | 0.29 | 0.34 | 0.37 |
| Cytosine | ME1227750 | 1.50 | 1.21 | 1.39 | 1.53 | 2.06 | 2.25 | 0.25 | 0.22 | 0.66 | 0.13 | 0.44 | 0.37 |
| 5-Aminopentanoic acid | ME1227702 | 1.02 | 0.99 | 0.72 | 1.58 | 0.80 | NA | 4.84 | NA | 1.84 | NA | 1.02 | 1.65 |
| N6-Isopentenyladenine | ME1227800 | 0.79 | 2.00 | 0.37 | NA | 2.56 | 0.39 | 3.06 | 1.11 | 0.87 | 0.37 | NA | 1.27 |
| Methylguanidine | ME1227797 | NA | 2.08 | NA | 1.23 | 1.96 | NA | 2.17 | NA | NA | 4.93 | 0.75 | 3.29 |
| Tyramine | ME1227865 | 0.47 | NA | 2.77 | 3.67 | NA | 0.13 | 3.15 | NA | NA | 2.56 | 1.26 | 3.71 |
Factors:
| F1 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:FXS_w1_1 |
| F2 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:FXS_w1_2 |
| F3 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:FXS_w1_3 |
| F4 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:FXS_w1_4 |
| F5 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:FXS_w1_5 |
| F6 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:FXS_w1_6 |
| F7 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:iControl_w1_1 |
| F8 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:iControl_w1_2 |
| F9 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:iControl_w1_3 |
| F10 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:iControl_w1_4 |
| F11 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:iControl_w1_5 |
| F12 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:iControl_w1_6 |
