Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST004495)

(Analysis AN007537)

Metabolite	Structure	F1	F2	F3	F4
L-Anserine	ME1260343	0.35	0.43	2.81	0.41
3-Isopropylmalic acid	ME1260311	0.15	0.15	3.55	0.15
Genistein	ME1260356	0.22	0.04	3.52	0.21
L-Glutathione (reduced)	ME1260375	0.33	0.02	3.51	0.14
N-Acetyl-D-galactosamine 4-sulfate	ME1260370	0.22	1.93	0.02	1.84
Deoxycholic Acid	ME1260389	2.74	0.44	0.04	0.78
Dodecanedioic acid	ME1260342	2.31	0.94	0.28	0.47
Adenosine 5^-monophosphate	ME1260386	1.76	1.19	0.39	0.66
2-Furoic acid	ME1260247	1.75	1.15	0.28	0.81
Orotidine	ME1260365	1.77	1.08	0.26	0.89
3,4-Dihydroxybenzenesulfonic acid	ME1260324	1.93	0.91	0.08	1.08
Uridine monophosphate (UMP)	ME1260378	2.03	0.94	0.24	0.79
(2R)-2,3-Dihydroxypropanoic acid	ME1260244	1.39	1.04	0.31	1.26
Isobutyric acid	ME1260233	1.73	0.74	0.40	1.13
Cholic acid	ME1260391	1.41	0.55	1.67	0.38
Glyoxylic acid	ME1260229	1.21	0.16	1.80	0.83
L-Threonic acid-1,4-lactone	ME1260255	1.25	0.47	1.47	0.81
5-Hydroxyindole-3-acetic acid	ME1260325	0.50	0.83	1.01	1.66
N-Acetylglycine	ME1260251	1.11	0.93	0.66	1.30
Ribose 5-phosphate	ME1260340	0.79	1.12	0.63	1.46
Myristyl sulfate	ME1260368	1.40	0.53	1.13	0.95
Citric acid	ME1260327	1.45	0.66	0.77	1.12
L-Cysteinesulfinic acid	ME1260291	1.48	0.65	0.84	1.03
Dodecyl sulfate	ME1260354	1.18	0.44	1.05	1.33
Salicylic acid	ME1260277	1.40	0.32	0.79	1.48
Crotonic acid	ME1260231	0.68	0.63	1.59	1.11
N-Formylmethionine	ME1260312	0.73	0.65	1.61	1.02
Glycyl-L-leucine	ME1260323	0.83	1.06	1.41	0.70
Tridecylic acid	ME1260335	0.81	0.94	1.40	0.84
Decanoic acid	ME1260304	0.83	0.72	1.63	0.83
Acamprosate	ME1260316	0.70	0.93	1.69	0.68
Undecanoic acid	ME1260322	0.70	0.93	1.55	0.82
3-Hydroxy-3-methylbutanoic acid	ME1260256	1.29	1.00	1.11	0.60
Hypoxanthine	ME1260275	1.26	1.03	0.98	0.73
Monobutyl phthalate	ME1260338	1.21	0.98	0.92	0.88
Hydrocinnamic acid	ME1260287	0.87	1.07	1.18	0.87
4-tert-Amylphenol	ME1260298	0.83	1.03	1.13	1.01
Pentadecanoic acid	ME1260345	0.88	1.03	1.07	1.02
Vanillin	ME1260289	1.16	0.84	1.03	0.97
Caprylic acid	ME1260280	1.00	0.84	1.07	1.10
Stearic acid	ME1260363	1.07	0.75	1.09	1.09
Maleic acid	ME1260250	0.96	0.80	1.26	0.98
Palmitic Acid	ME1260351	1.03	0.83	1.14	0.99
Lauric acid	ME1260330	1.00	0.93	1.13	0.95
Nonanoic acid	ME1260293	0.97	0.89	1.17	0.97
Adipic acid	ME1260282	1.00	0.65	1.25	1.10
Heptanoic acid	ME1260264	0.85	0.62	1.23	1.30
Citraconic acid	ME1260262	1.07	0.71	0.96	1.26
4-Dodecylbenzenesulfonic acid	ME1260380	0.79	0.88	1.06	1.28
2-Naphthalenesulfonic acid	ME1260332	0.87	0.71	0.99	1.43
Uric acid	ME1260301	0.85	0.80	0.99	1.36
Phosphocreatine	ME1260333	0.67	1.79	0.33	1.22
L-Citrulline	ME1260309	0.53	1.73	0.33	1.42
Ornithine	ME1260270	0.55	1.75	0.31	1.39
PG(18:2(9Z,12Z)/0:0)	ME1260396	0.56	1.69	0.37	1.39
α-Linolenic acid	ME1260359	0.53	1.73	0.38	1.36
Linoleic acid	ME1260360	0.53	1.67	0.29	1.51
N-Glycolylneuraminic acid	ME1260379	0.57	1.56	0.35	1.52
Adenosine	ME1260355	1.05	1.39	0.26	1.29
N-α-Acetyl-L-asparagine	ME1260364	1.19	1.43	0.23	1.15
DL-Tryptophan	ME1260331	0.97	1.40	0.43	1.19
O-Phosphorylethanolamine	ME1260279	0.87	1.41	0.49	1.23
N-Acetyl-L-methionine	ME1260326	0.85	1.53	0.35	1.27
3-Indoxyl sulphate	ME1260334	0.86	1.59	0.21	1.34
5-Aminolevulinic acid	ME1260266	0.93	1.53	0.21	1.33
Cytidine	ME1260346	0.90	1.49	0.25	1.36
Fumaric acid	ME1260249	1.25	1.58	0.17	0.99
Perillic acid	ME1260300	1.27	1.64	0.27	0.82
N-Acetyl-α-D-glucosamine 1-phosphate	ME1260371	1.14	1.55	0.39	0.92
L-Aspartic acid	ME1260271	1.14	1.47	0.31	1.08
DL-3-Aminoisobutyric acid	ME1260238	1.09	1.54	0.35	1.02
L-Glutamic acid	ME1260284	1.10	1.53	0.36	1.02
D-Sedoheptulose 7-phosphate	ME1260366	1.10	1.39	0.44	1.08
2-Methylbenzoic acid	ME1260276	1.04	1.41	0.54	1.01
Fructose-6-phosphate	ME1260353	1.08	1.48	0.50	0.94
Thymidine	ME1260344	0.90	1.67	0.27	1.16
Xylulose 5-phosphate	ME1260341	0.79	1.66	0.43	1.12
2-Aminoadipic acid	ME1260294	0.89	1.60	0.39	1.12
Gluconic acid	ME1260329	0.88	1.59	0.37	1.16
L-Phenylalanine	ME1260299	0.84	1.77	0.39	0.99
Threonine	ME1260257	0.84	1.79	0.30	1.07
1,5-Anhydro-D-glucitol	ME1260297	0.99	1.58	0.44	0.99
3-Coumaric acid	ME1260296	0.99	1.66	0.39	0.97
L-Tyrosine	ME1260317	0.96	1.66	0.41	0.97
L-Serine	ME1260243	0.97	1.69	0.26	1.08
D-(-)-Lyxose	ME1260286	0.95	1.71	0.33	1.01
Glutamine	ME1260283	0.96	1.72	0.32	1.00
2-Acetamido-N-β-aspartyl-2-deoxyhexopyranosylamine	ME1260384	1.17	1.64	0.40	0.79
Glycerol 3-phosphate	ME1260303	1.10	1.67	0.35	0.88
Pseudouridine	ME1260347	1.02	1.72	0.37	0.89
Argininosuccinic acid	ME1260367	0.84	1.64	0.54	0.97
N-Acetylornithine	ME1260306	0.85	1.69	0.57	0.89
Glucose 6-phosphate	ME1260352	0.94	1.60	0.56	0.90
L-Glutathione oxidized	ME1260403	0.98	1.64	0.48	0.89
Methylmalonic acid	ME1260254	1.03	1.60	0.51	0.86
Glycerophospho-N-palmitoyl ethanolamine	ME1260394	0.85	2.00	0.53	0.62
Flavin adenine dinucleotide (FAD)	ME1260406	0.77	1.89	0.65	0.68
β-D-Glucopyranuronic acid	ME1260328	0.73	1.76	0.72	0.79
Asparagine	ME1260269	0.85	2.12	0.22	0.81
Succinic semialdehyde	ME1260236	0.77	2.06	0.29	0.87
4-Oxoproline	ME1260260	0.78	1.97	0.28	0.98
DL-Arginine	ME1260307	0.66	2.09	0.25	0.99
D-α-Hydroxyglutaric acid	ME1260285	0.72	1.91	0.47	0.90
Palmitoleic Acid	ME1260349	0.69	1.90	0.44	0.97
DL-4-Hydroxyphenyllactic acid	ME1260318	0.58	1.98	0.30	1.14
α-D-Glucose-1,6-bisphosphate	ME1260385	0.56	2.04	0.39	1.01
N-Acetylaspartic acid	ME1260308	0.82	1.97	0.06	1.15
cis-Aconitic acid	ME1260305	0.95	1.85	0.17	1.03
Glycine	ME1260230	0.82	1.88	0.22	1.08
1-Methylhistidine	ME1260302	1.15	1.91	0.17	0.76
Xylitol	ME1260290	1.02	1.82	0.30	0.85
5^-S-Methyl-5^-thioadenosine	ME1260369	1.02	1.89	0.24	0.85
Adenine	ME1260273	1.01	1.89	0.25	0.85
UDP-N-acetylglucosamine	ME1260402	0.90	1.97	0.36	0.77
5-Aminovaleric acid	ME1260252	0.86	1.95	0.33	0.86
DL-β-Leucine	ME1260268	0.90	1.90	0.33	0.88
Hypotaurine	ME1260245	1.70	1.33	0.48	0.49
Itaconic acid	ME1260261	1.51	1.45	0.59	0.44
Adenosine diphosphate ribose	ME1260398	1.31	1.29	0.59	0.80
Taurine	ME1260259	1.21	1.18	0.68	0.92
N-Ethylglycine	ME1260239	1.13	1.32	0.66	0.90
β-Alanine	ME1260234	1.08	1.33	0.68	0.91
Guanosine monophosphate (GMP)	ME1260388	1.47	1.42	0.47	0.64
N-Arachidonoyl taurine	ME1260392	1.38	1.44	0.46	0.73
D-(-)-Mannitol	ME1260319	1.35	1.19	0.44	1.02
2-Oxoglutaric acid	ME1260281	1.35	1.33	0.43	0.89
Pyrrole-2-carboxylic acid	ME1260246	1.42	1.34	0.35	0.90
Uridine	ME1260348	1.44	1.30	0.33	0.92
3-Hydroxy-3-methylglutaric acid	ME1260295	1.07	1.55	0.72	0.67
D-(-)-Fructose	ME1260315	1.07	1.56	0.71	0.66
Pantothenic acid	ME1260337	1.08	1.64	0.53	0.75
Uracil	ME1260248	1.13	1.59	0.56	0.73
Υ-Aminobutyric acid (GABA)	ME1260240	1.02	1.32	0.99	0.68
Eicosapentaenoic acid	ME1260372	0.99	1.49	0.89	0.63
Cyclic ADP-ribose	ME1260397	0.95	1.51	0.88	0.66
Nicotinamide adenine dinucleotide	ME1260404	0.97	1.49	0.88	0.66
L-Ascorbic acid 2-sulfate	ME1260350	1.17	1.39	0.90	0.53
Ascorbic acid	ME1260310	1.09	1.43	0.89	0.58
Inosine-5^-monophosphate (IMP)	ME1260387	1.09	1.50	0.85	0.56
cis-4-Hydroxy-D-proline	ME1260265	0.65	1.18	1.24	0.93
Mesaconic acid	ME1260263	0.58	1.34	1.09	0.99
Xanthosine	ME1260362	0.72	1.38	1.08	0.82
2,4-Dinitrophenol	ME1260320	0.62	1.49	0.82	1.07
Lactic acid	ME1260235	0.95	1.34	0.70	1.00
(+/-)12(13)-DiHOME	ME1260377	0.83	1.46	0.74	0.98
Arachidonic acid	ME1260373	0.91	1.44	0.70	0.96
12-Hydroxydodecanoic acid	ME1260336	0.99	1.34	0.84	0.83
δ-Gluconic acid δ-lactone	ME1260313	0.88	1.33	0.92	0.87
Myristic acid	ME1260339	0.95	1.11	0.96	0.98
4-Hydroxybenzaldehyde	ME1260258	0.96	1.17	0.96	0.90
Xanthine	ME1260288	0.93	1.18	0.95	0.94
16-Hydroxyhexadecanoic acid	ME1260357	1.06	1.14	0.96	0.84
Creatine	ME1260267	1.05	1.21	0.87	0.86
Valeric acid	ME1260237	0.99	1.13	0.83	1.05
Pyruvic acid	ME1260232	0.96	1.23	0.74	1.08
11(E)-Eicosenoic Acid	ME1260376	0.96	1.16	0.73	1.16
Guanosine	ME1260361	0.94	1.16	0.77	1.13
4-Nitrophenol	ME1260278	0.79	1.12	0.86	1.23
Adenosine 3^5^-cyclic monophosphate	ME1260382	0.73	1.26	0.81	1.20
Adenosine triphosphate (ATP)	ME1260395	0.24	3.06	0.31	0.39
DL-Malic acid	ME1260272	1.21	2.36	0.02	0.41
3-Hydroxybutyric acid	ME1260242	0.79	2.36	0.15	0.71
Guanosine 5^-diphospho-ß-L-fucose	ME1260400	0.96	2.13	0.44	0.47
Guanosine 5^-diphospho-D-mannose	ME1260401	0.91	2.25	0.39	0.45
L-Threonic acid	ME1260274	0.89	2.23	0.34	0.53
8Z,11Z,14Z-Eicosatrienoic acid	ME1260374	0.59	2.41	0.56	0.43
Nicotinamide adenine dinucleotide phosphate	ME1260405	0.64	2.44	0.44	0.47
Adenosine diphosphate (ADP)	ME1260393	0.74	2.23	0.40	0.64
Succinic acid	ME1260253	0.67	2.34	0.41	0.58
Uridine 5^-diphosphate (UDP)	ME1260390	0.54	2.39	0.46	0.60
Adrenic acid	ME1260383	0.58	2.29	0.45	0.68
Docosahexaenoic acid	ME1260381	0.57	2.24	0.43	0.76
3-Phosphoglyceric acid	ME1260321	0.45	2.50	0.06	0.99
6-Phosphogluconic acid	ME1260358	0.24	2.55	0.22	0.99
L-Histidine	ME1260292	0.48	2.79	0.02	0.71
Uridine 5^-diphosphoglucuronic acid	ME1260399	0.42	2.75	0.35	0.48
Hippuric acid	ME1260314	0.39	2.67	0.30	0.64
Malonic acid	ME1260241	0.46	2.60	0.25	0.69

Factors:

F1	Genotype:TIGAR-knockout \| Treatment:Control \| Sample source:colon
F2	Genotype:TIGAR-knockout \| Treatment:DSS \| Sample source:colon
F3	Genotype:Wild-type \| Treatment:Control \| Sample source:colon
F4	Genotype:Wild-type \| Treatment:DSS \| Sample source:colon

Data matrix