Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Murine gastrointestinal bile acid profiles before and after antibiotics (Study ST000196)

ESI negative ion mode (Analysis AN000298)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12	F13	F14	F15	F16	F17	F18	F19	F20	F21	F22	F23	F24	F25	F26
Taurodeoxycholic acid	ME697853	0.04	0.22	0.66	0.01	10.00	1.90	0.00	0.01	5.48	0.55	0.00	0.00	0.00	0.15	0.00	0.00	0.00	0.00	0.18	0.03	0.01	0.00	0.21	1.48	0.89	0.81
Glycolithocholic acid	ME697843	0.55	0.88	0.81	1.28	4.31	1.20	0.21	0.26	1.18	2.96	0.20	0.20	0.48	0.83	0.22	0.33	0.49	0.16	1.61	0.84	0.54	0.27	1.72	0.34	1.63	0.82
Ursodeoxycholic acid	ME697856	0.79	0.48	0.87	0.47	8.09	2.79	0.00	0.00	1.41	2.47	0.01	0.00	0.00	0.17	0.12	0.13	1.43	0.07	0.51	0.02	0.13	0.01	0.81	0.65	2.05	0.52
Isolithocholic acid	ME697847	0.09	0.18	1.12	0.73	7.02	1.68	0.04	0.08	0.96	1.44	0.20	0.09	0.72	0.83	0.14	0.17	0.47	0.14	2.51	0.42	0.41	1.28	0.62	0.61	1.10	0.90
Lithocholic acid	ME697848	0.27	0.14	2.01	0.59	7.55	1.79	0.02	0.03	1.46	2.18	0.07	0.02	1.01	0.62	0.11	0.09	0.18	0.03	1.28	1.50	0.17	1.30	0.61	0.40	1.44	0.85
Deoxycholic acid	ME697837	0.48	0.37	2.05	0.48	7.96	1.44	0.00	0.00	1.31	1.76	0.00	0.00	0.03	0.44	0.04	0.00	0.02	0.00	2.35	0.02	0.18	0.00	0.66	0.61	3.41	0.83
Glycodeoxycholic acid	ME697840	0.38	0.40	1.34	0.28	6.71	1.22	0.01	0.02	1.83	1.22	0.02	0.00	0.03	0.21	0.03	0.01	0.01	0.02	0.72	0.05	0.09	0.06	0.42	1.87	2.33	0.70
Taurolithocolic acid	ME697855	0.98	0.21	2.30	0.25	1.97	1.59	0.09	0.83	3.09	0.31	0.17	0.16	0.21	0.55	0.05	0.34	0.10	0.09	0.31	1.84	0.19	0.88	0.43	0.78	6.14	0.66
Glychocholic acid	ME697838	1.99	0.40	0.89	0.18	1.86	1.66	0.07	0.22	1.14	0.63	0.03	0.02	0.07	0.30	0.20	0.05	4.12	0.06	0.81	0.26	0.13	0.01	2.62	3.50	2.07	0.61
Glycoursodeoxycholic acid	ME697844	1.16	0.36	0.74	0.18	2.01	0.65	0.61	0.11	1.05	0.81	0.19	0.18	0.18	0.17	0.21	0.07	6.82	0.13	0.69	0.34	0.11	0.09	1.31	2.77	1.63	0.65
g-Muricholic acid (hyocholic acid)	ME697845	1.14	1.53	1.43	3.79	0.35	1.29	0.01	0.00	2.48	0.26	0.01	0.00	0.00	0.55	0.58	0.09	2.75	0.22	0.80	0.04	0.05	0.03	1.01	3.53	3.11	0.58
Chenodeoxycholic acid	ME697836	0.93	1.20	2.17	0.98	0.54	2.01	0.03	0.09	2.12	0.25	0.04	0.02	0.01	0.25	0.14	0.35	1.05	0.45	0.96	0.34	0.47	0.13	1.60	2.23	4.31	2.39
?a-Muricholic acid	ME697833	1.79	1.03	2.09	2.33	1.39	1.63	0.00	0.02	1.36	0.66	0.01	0.00	0.00	0.33	0.14	0.29	2.50	0.18	1.82	0.18	0.82	0.05	2.63	1.31	2.65	1.46
b-Muricholic acid	ME697834	1.81	1.19	1.88	1.56	0.72	1.51	0.00	0.01	2.12	0.85	0.01	0.01	0.00	0.43	0.28	0.57	2.59	0.43	1.65	0.13	0.70	0.03	2.46	1.69	2.28	1.25
Cholic acid	ME697835	1.50	0.96	1.89	1.36	0.97	1.89	0.15	0.07	1.73	0.73	0.19	0.02	0.03	0.31	0.29	0.73	2.24	0.61	1.62	0.36	0.57	0.08	2.29	1.60	2.33	1.02
Hyodeoxycholic acid	ME697846	1.24	1.66	1.70	3.11	1.53	2.19	0.01	0.01	1.49	0.96	0.01	0.00	0.01	0.56	0.16	0.15	0.75	0.12	1.97	0.05	1.66	0.09	1.53	1.79	2.43	2.32
w-Muricholic acid	ME697857	1.77	1.08	1.22	2.57	1.74	2.27	0.01	0.01	1.88	1.47	0.01	0.01	0.01	0.88	0.48	0.29	1.04	0.22	2.60	0.01	1.57	0.07	1.90	1.16	1.94	1.41
Taurochenodeoxycholic acid	ME697852	0.04	0.48	1.13	0.02	5.20	2.55	1.24	0.49	3.15	0.28	1.26	0.12	0.38	0.43	0.01	0.26	0.11	0.82	0.16	0.33	0.01	0.03	0.40	2.37	0.91	1.13
3a,7a,12a-trihydroxycholestanoic acid	ME697854	0.03	0.73	0.21	0.62	1.04	1.96	1.60	0.30	1.34	0.76	1.69	0.63	1.49	2.60	0.11	0.63	1.94	1.69	0.06	0.57	0.34	0.18	0.13	1.18	0.64	2.10
Glycohyocholic acid	ME697841	1.03	1.34	0.56	0.97	1.25	0.93	2.72	0.40	0.36	0.28	1.32	1.24	0.57	0.39	0.12	0.72	1.40	0.65	0.86	0.75	0.55	0.19	1.07	2.54	2.00	0.73
Tauro-alpha-muricholic acid	ME697849	0.46	0.89	1.32	1.40	2.10	1.78	1.06	0.50	0.96	0.49	1.98	0.17	0.70	0.54	0.08	0.35	2.02	2.32	0.48	0.50	0.70	0.07	0.74	1.43	0.83	1.30
Taurocholic acid	ME697851	0.39	0.57	0.57	0.12	3.75	1.53	1.35	0.72	1.37	1.02	1.48	0.78	0.88	0.80	0.07	0.78	0.80	2.13	0.30	0.75	0.08	0.12	0.82	0.90	1.30	1.01
Tauro-beta-muricholic acid	ME697850	0.44	1.14	0.97	0.81	3.06	1.42	1.03	0.53	1.17	0.71	0.92	0.61	0.54	0.60	0.13	0.81	1.73	1.07	0.55	0.70	0.35	0.13	0.97	1.38	1.79	1.14
TAUROHYODEOXYCHOLIC ACID	ME697858	0.20	1.01	1.19	0.25	3.95	1.90	0.51	0.58	0.93	0.62	1.04	0.42	0.61	0.40	0.04	0.55	1.86	1.22	0.65	0.63	0.12	0.09	0.66	1.48	1.70	1.38
Glycochenodeoxycholic acid	ME697839	0.99	0.85	0.88	0.59	3.13	1.82	0.75	0.56	1.34	0.85	0.53	0.37	0.95	0.62	0.18	0.26	1.03	0.26	0.65	0.82	0.28	0.17	0.97	2.80	1.53	1.26
Glycohyodeoxycholic acid	ME697842	1.04	1.01	0.84	0.37	3.05	1.12	1.93	0.40	1.44	0.43	0.91	0.52	1.01	0.45	0.08	0.33	1.25	0.36	0.80	0.99	0.36	0.09	0.78	1.75	1.96	1.37

Factors:

F1	Recovery:five week recovery \| Gender:female \| Treatment:Cefoperazone treated
F2	Recovery:five week recovery \| Gender:male \| Treatment:Cefoperazone treated
F3	Recovery:four week recovery \| Gender:female \| Treatment:Cefoperazone treated
F4	Recovery:four week recovery \| Gender:male \| Treatment:Cefoperazone treated
F5	Recovery:na \| Gender:female \| Treatment:No antibiotics
F6	Recovery:na \| Gender:male \| Treatment:No antibiotics
F7	Recovery:no recovery \| Gender:female \| Treatment:Cefoperazone treated
F8	Recovery:no recovery \| Gender:female \| Treatment:IP clindamycin
F9	Recovery:no recovery \| Gender:female \| Treatment:Kanamycin treated
F10	Recovery:no recovery \| Gender:female \| Treatment:Metronidazole treated
F11	Recovery:no recovery \| Gender:female \| Treatment:Vancomycin treated
F12	Recovery:no recovery \| Gender:male \| Treatment:Cefoperazone treated
F13	Recovery:no recovery \| Gender:male \| Treatment:IP clindamycin
F14	Recovery:no recovery \| Gender:male \| Treatment:Kanamycin treated
F15	Recovery:no recovery \| Gender:male \| Treatment:Metronidazole treated
F16	Recovery:no recovery \| Gender:male \| Treatment:Vancomycin treated
F17	Recovery:one week recovery \| Gender:female \| Treatment:Cefoperazone treated
F18	Recovery:one week recovery \| Gender:male \| Treatment:Cefoperazone treated
F19	Recovery:six week recovery \| Gender:female \| Treatment:Cefoperazone treated
F20	Recovery:six week recovery \| Gender:female \| Treatment:Cefoperazone treated IP clindamycin
F21	Recovery:six week recovery \| Gender:male \| Treatment:Cefoperazone treated
F22	Recovery:six week recovery \| Gender:male \| Treatment:Cefoperazone treated IP clindamycin
F23	Recovery:three week recovery \| Gender:female \| Treatment:Cefoperazone treated
F24	Recovery:three week recovery \| Gender:male \| Treatment:Cefoperazone treated
F25	Recovery:two week recovery \| Gender:female \| Treatment:Cefoperazone treated
F26	Recovery:two week recovery \| Gender:male \| Treatment:Cefoperazone treated

Data matrix