Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Sprague Dawley rats Nicotine alters brain oxidative metabolism (Study ST000235)

ESI negative ion mode (Analysis AN000354)

Metabolite	Structure	F1	F2	F3	F4
4-METHYLCATECHOL	ME699309	0.04	2.69	1.25	0.02
GLYCEROL 2-PHOSPHATE	ME699321	0.52	2.03	1.08	0.36
CYTIDINE	ME699295	1.22	0.56	0.72	1.51
HYPOTAURINE	ME699322	1.79	0.55	0.48	1.18
GLUTATHIONE	ME699318	1.05	1.50	0.90	0.55
BETA-ALANINE	ME699299	0.85	1.05	1.52	0.57
CITRULLINE	ME699298	0.71	1.11	1.48	0.71
N-ACETYL-L-ALANINE	ME699280	0.73	1.08	1.42	0.77
ALPHA-AMINOADIPATE	ME699300	0.86	1.05	1.02	1.08
D-RIBOSE 5-PHOSPHATE	ME699294	0.90	0.94	1.11	1.04
L-ASPARAGINE	ME699290	0.92	0.99	1.10	0.99
L-SERINE	ME699284	0.91	0.98	1.09	1.02
CMP	ME699297	0.93	1.05	1.07	0.95
NICOTINAMIDE	ME699277	0.91	1.05	1.09	0.94
D-XYLOSE	ME699316	0.90	1.04	1.03	1.03
URACIL	ME699275	0.92	1.03	1.04	1.01
N-ACETYL-DL-GLUTAMIC ACID	ME699281	0.87	1.04	1.09	0.99
N-ACETYL-D-MANNOSAMINE	ME699326	0.86	1.06	1.10	0.98
(R)-MALATE	ME699307	0.89	1.02	1.09	1.00
L-GLUTAMINE	ME699323	0.90	1.04	1.07	0.99
N-ACETYLNEURAMINATE	ME699278	0.90	1.02	1.07	1.00
DIHYDROXYACETONE PHOSPHATE	ME699313	0.87	1.10	1.03	1.00
L-THREONINE	ME699283	0.80	1.10	1.10	1.00
N-ACETYL-D-GALACTOSAMINE	ME699282	0.84	1.11	1.07	0.99
L-ASPARTATE	ME699289	0.84	1.11	1.13	0.93
L-VALINE	ME699324	0.86	1.03	1.15	0.96
L-ANSERINE	ME699292	0.82	1.26	1.06	0.86
SUBERIC ACID	ME699328	0.94	1.13	1.06	0.86
L-ARGININE	ME699291	0.76	1.18	1.29	0.78
L-LYSINE	ME699286	0.70	1.12	1.30	0.88
L-HISTIDINE	ME699287	0.81	1.10	1.26	0.83
LEUCINE	ME699288	0.81	1.08	1.21	0.90
L-METHIONINE	ME699285	0.79	1.10	1.24	0.88
5-AMINOLEVULINIC ACID	ME699303	0.87	0.96	1.27	0.90
MALONATE	ME699325	0.76	0.95	1.24	1.05
GLYCERATE	ME699320	0.85	1.02	0.90	1.23
URATE	ME699274	0.91	1.00	0.84	1.25
D-GLUCOSE-6-PHOSPHATE	ME699312	1.09	0.86	1.05	0.99
4-GUANIDINOBUTANOATE	ME699304	0.91	0.86	1.09	1.13
5-OXO-L-PROLINE	ME699302	0.95	0.91	1.03	1.12
3-SULFINO-L-ALANINE	ME699308	0.99	0.92	0.93	1.16
ETHANOLAMINE PHOSPHATE	ME699293	1.02	0.94	0.94	1.11
N-ACETYL-L-ASPARTIC ACID	ME699279	1.02	0.93	0.93	1.11
3-HYDROXY-3-METHYLGLUTARATE	ME699305	1.04	0.84	0.95	1.18
ADENOSINE 5^-MONOPHOSPHATE	ME699310	1.02	0.88	0.88	1.22
D-SORBITOL	ME699315	0.99	1.05	0.88	1.08
GLYCERALDEHYDE	ME699319	0.94	1.01	0.97	1.07
2-HYDROXYPHENYLACETIC ACID	ME699306	1.01	1.00	0.98	1.01
Creatine	ME699296	0.99	0.99	0.98	1.04
GLUCONIC ACID	ME699317	0.98	0.99	1.00	1.03
D-SACCHARIC ACID	ME699314	1.13	0.62	1.02	1.23
ADENINE	ME699301	1.07	0.77	0.84	1.33
ALPHA-KETOGLUTARIC ACID	ME699311	1.10	0.76	0.90	1.24
N-METHYL-D-ASPARTIC ACID	ME699327	1.11	0.87	0.86	1.15
TAURINE	ME699276	1.16	0.82	0.79	1.23

Factors:

F1	Treatment:Nicotine \| Dosage:6mg/kg
F2	Treatment:Nicotine + Oral contraceptives \| Dosage:6mg/kg Nicotine
F3	Treatment:Oral contraceptives \| Dosage:1 mL
F4	Treatment:Saline \| Dosage:2 mL

Data matrix