Clustering data with hclust algorithm for Timecourse of Amino Acid Metabolites in LNCaP Cell pellets (Study ST000505)
Reversed phase POSITIVE ION MODE (Analysis AN000774)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|---|
| Phosphoethanolamine | ME156264 | NA | 1.07 | NA | 0.54 | 0.36 | 0.71 | 0.54 | 2.32 |
| alpha-Amino-N-butyric-acid | ME156276 | 1.00 | 1.00 | 1.00 | NA | NA | NA | NA | 1.00 |
| 1-Methylhistidine | ME156262 | 0.83 | 1.03 | 1.42 | 0.77 | 0.26 | 0.66 | 0.59 | 1.57 |
| Tryptophan | ME156301 | 1.18 | 0.26 | 1.17 | NA | 1.27 | 0.05 | 1.44 | 1.29 |
| Taurine | ME156284 | 1.17 | 0.46 | 1.17 | 0.63 | 1.43 | 0.42 | 1.59 | 1.05 |
| Methionine | ME156279 | 1.22 | 0.66 | 1.20 | 0.52 | 1.25 | 0.58 | 1.28 | 1.21 |
| Arginine | ME156283 | 1.30 | 0.55 | 1.34 | 0.53 | 1.43 | 0.66 | 1.35 | 0.88 |
| Serine | ME156285 | 1.38 | 0.52 | 1.36 | 0.38 | 1.38 | 0.47 | 1.40 | 1.03 |
| Homocystine | ME156281 | 1.26 | 0.99 | 1.16 | 0.87 | 1.24 | 0.84 | 1.01 | 0.67 |
| 3-Methylhistidine | ME156263 | 1.08 | 0.70 | 1.10 | 0.96 | 0.96 | 1.08 | 1.01 | 1.14 |
| Cystine | ME156295 | 1.13 | 0.78 | 1.22 | 0.76 | 1.22 | 0.77 | 1.19 | 0.93 |
| Proline | ME156292 | 0.99 | 1.02 | 0.95 | 0.93 | 0.99 | 0.91 | 1.04 | 1.13 |
| Hydroxyproline | ME156261 | 0.98 | 0.96 | 1.00 | 0.98 | 1.09 | 1.03 | 1.02 | 1.00 |
| Asparagine | ME156282 | 1.06 | 0.94 | 1.02 | 0.92 | 0.98 | 0.93 | 1.06 | 1.04 |
| Aspartic Acid | ME156268 | 1.01 | 0.95 | 1.07 | 0.95 | 1.03 | 0.95 | 1.02 | 1.01 |
| Histidine | ME156260 | 1.06 | 0.93 | 0.97 | 0.82 | 1.15 | 0.74 | 1.20 | 1.08 |
| Leucine | ME156299 | 1.10 | 0.88 | 1.10 | 0.81 | 1.11 | 0.82 | 1.11 | 1.04 |
| Isoleucine | ME156298 | 1.05 | 0.93 | 1.06 | 0.89 | 1.08 | 0.88 | 1.07 | 1.02 |
| Tyrosine | ME156296 | 1.03 | 0.91 | 1.09 | 0.84 | 1.11 | 0.85 | 1.08 | 1.06 |
| Lysine | ME156294 | 1.08 | 0.85 | 1.06 | 0.81 | 1.03 | 0.85 | 1.17 | 1.09 |
| Valine | ME156297 | 1.11 | 0.82 | 1.12 | 0.75 | 1.13 | 0.73 | 1.15 | 1.13 |
| Phenylalanine | ME156300 | 1.07 | 0.85 | 1.07 | 0.77 | 1.10 | 0.78 | 1.15 | 1.16 |
| Threonine | ME156290 | 1.06 | 0.88 | 1.07 | 0.79 | 1.08 | 0.79 | 1.13 | 1.13 |
| Sarcosine | ME156269 | NA | 0.82 | NA | 1.65 | NA | 1.24 | NA | 0.41 |
| Glutamic Acid | ME156289 | 0.74 | 1.37 | 0.73 | 1.35 | 0.76 | 1.20 | 0.77 | 1.06 |
| Alanine | ME156291 | 0.65 | 1.38 | 0.63 | 1.19 | 0.62 | 1.20 | 0.67 | 1.57 |
| Glycine | ME156287 | 0.70 | 1.30 | 0.71 | 1.28 | 0.71 | 1.20 | 0.69 | 1.36 |
| alpha-Aminoadipic-acid | ME156272 | 0.39 | 1.18 | 0.39 | 1.77 | 0.39 | 1.18 | 0.39 | 1.77 |
| Glutamine | ME156286 | 0.49 | 1.17 | 0.47 | 1.79 | 0.53 | 1.88 | 0.50 | 1.37 |
| Cystathionine 1 | ME156277 | 0.37 | 1.72 | 0.38 | 1.77 | 0.36 | 1.86 | 0.37 | 1.29 |
| Ornithine | ME156293 | 0.37 | 1.87 | 0.36 | 1.90 | 0.34 | 1.53 | 0.31 | 1.24 |
Factors:
| F1 | Treatment Factor:treated-100 pM R1881 | 13C media incubation time:24 hours |
| F2 | Treatment Factor:treated-100 pM R1881 | 13C media incubation time:72 hours |
| F3 | Treatment Factor:treated-10 nM R1881 | 13C media incubation time:24 hours |
| F4 | Treatment Factor:treated-10 nM R1881 | 13C media incubation time:72 hours |
| F5 | Treatment Factor:treated-1 nM R1881 | 13C media incubation time:24 hours |
| F6 | Treatment Factor:treated-1 nM R1881 | 13C media incubation time:72 hours |
| F7 | Treatment Factor:treated-vehicle (ethanol) | 13C media incubation time:24 hours |
| F8 | Treatment Factor:treated-vehicle (ethanol) | 13C media incubation time:72 hours |
